Asbestos exposure in lung carcinoma: a necropsy-based study of 414 cases.

Abstract:

BACKGROUND:The prerequisites necessary for attributing lung carcinoma to asbestos, represent a controversial issue. METHODS:Three parameters (occupational history, pleural plaques, and lung asbestos bodies) were investigated in 414 consecutive cases of lung carcinoma, examined at necropsy at the Hospital of Monfalcone, Italy. Occupational data were obtained from the patients' relatives by personal or telephone interviews. Pleural plaques were classified into three classes (small, moderate, large). Routine lung sections were examined for asbestos bodies in all cases; isolation and counting were performed in 408 cases. RESULTS:The series included 353 men, and 61 women, aged between 38 and 97 years. The male patients had worked in industries in 74% of cases (60% in shipbuilding). Men showed pleural plaques in 82% of cases (moderate or large plaques in 58.7%). Asbestos bodies were observed in routine lung sections in 34.8%, and in 31% exceeded the value of 5,000 bodies per gram of dried tissue. Among women the principal features were: history or domestic exposure to asbestos in 36% of the cases, prevalence of pleural plaques 34% (moderate or large plaques 15%), asbestos bodies in routine lung sections in 3.3% and there was no case with an asbestos body burden over 5,000/g. The fraction of asbestos-related carcinomas among male patients varied between 24.7 and 61%, depending on the criteria used for attribution. CONCLUSIONS:Different criteria indicated about 60% of the present lung carcinomas among men as plausibly attributable to asbestos.

journal_name

Am J Ind Med

authors

Bianchi C,Brollo A,Ramani L,Zuch C

doi

10.1002/(sici)1097-0274(199909)36:3<360::aid-ajim3

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

360-4

issue

3

eissn

0271-3586

issn

1097-0274

pii

10.1002/(SICI)1097-0274(199909)36:3<360::AID-AJIM3

journal_volume

36

pub_type

杂志文章
  • Longitudinal study of probable post-traumatic stress disorder in firefighters exposed to the World Trade Center disaster.

    abstract:BACKGROUND:Symptoms of post-traumatic stress disorder (PTSD) have been reported even years after the terrorist attacks of September 11, 2001 (9/11). METHODS:We used screening tools to assess the prevalence of probable PTSD in 9/11-exposed firefighters at two time points, within 6 months of 9/11 (baseline) and 3-4 year...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20894

    authors: Berninger A,Webber MP,Niles JK,Gustave J,Lee R,Cohen HW,Kelly K,Corrigan M,Prezant DJ

    更新日期:2010-12-01 00:00:00

  • A strategy to reduce healthy worker effect in a cross-sectional study of asthma and metalworking fluids.

    abstract::This report describes the reanalysis of a cross-sectional study of asthma in a large cohort of autoworkers with exposure to metalworking fluids (MWF). There is strong evidence from case reports, clinical studies, and medical surveillance data that exposure to MWF can cause asthma, yet no association was found in the o...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199706)31:6<671::aid-ajim1

    authors: Eisen EA,Holcroft CA,Greaves IA,Wegman DH,Woskie SR,Monson RR

    更新日期:1997-06-01 00:00:00

  • Occupational allergy and asthma among salt water fish processing workers.

    abstract:BACKGROUND:Fish processing is a common economic activity in Southern Africa. The aim of this study was to determine the prevalence and host determinants of allergic symptoms, allergic sensitization, bronchial hyper-responsiveness and asthma among workers processing saltwater fish. METHODS:A cross-sectional study was c...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20635

    authors: Jeebhay MF,Robins TG,Miller ME,Bateman E,Smuts M,Baatjies R,Lopata AL

    更新日期:2008-12-01 00:00:00

  • Reliability of an expert rating procedure for retrospective assessment of occupational exposures in community-based case-control studies.

    abstract::The most daunting problem in community-based studies of occupational cancer is retrospective exposure assessment. To avoid the error involved in using job title as the exposure variable or self-report of exposure, our team developed an approach based on expert judgment applied to job descriptions obtained by interview...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199703)31:3<280::aid-ajim3

    authors: Siemiatycki J,Fritschi L,Nadon L,Gérin M

    更新日期:1997-03-01 00:00:00

  • PCBs in blood of workers exposed to PCBs and their health status.

    abstract::Fact-finding surveys of workers occupationally exposed to polychlorinated biphenyls (PCBs) in the production of silk thread or of paint were carried out. Some of the workers showed higher PCB levels in the plasma than typical yusho patients. Gas chromatographic patterns of their PCBs were shown to match the pattern of...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:

    authors: Takamatsu M,Oki M,Maeda K,Inoue Y,Hirayama H,Yoshizuka K

    更新日期:1984-01-01 00:00:00

  • Attenuation of vagal recovery during sleep and reduction of cortisol/melatonin ratio in late afternoon associate with prolonged daytime sleepiness among media workers with irregular shift work.

    abstract:BACKGROUND:Media work is characterized by information flow, deadlines, and 24/7 alertness. Good recovery prevents stress-related disorders. METHODS:The standardized questionnaire included items about health, health habits, sleep, work conditions, and work stress. Recordings of 24-hr heart rate variability (HRV) and fo...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22042

    authors: Lindholm H,Sinisalo J,Ahlberg J,Hirvonen A,Hublin C,Partinen M,Savolainen A

    更新日期:2012-07-01 00:00:00

  • Lung cancer and diesel exhaust: a review.

    abstract::The evidence from animal studies indicates that organic extracts of diesel particulate are mutagenic and carcinogenic. Of four animal inhalation studies, two have been positive and two have been largely negative. The most recent data indicate that inhalation studies may be positive only with high doses of exhaust. Hum...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700100208

    authors: Steenland K

    更新日期:1986-01-01 00:00:00

  • Test-retest reliability of an icon/calendar-based questionnaire used to assess occupational history.

    abstract:BACKGROUND:Self-reported work histories can be critical for both epidemiologic and clinical purposes. However, the complexity of some work histories, such as those of migrant farm workers, can hamper recall, resulting in inaccurate reporting. Memory aids may reduce such error. This study assesses the reliability of wor...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.1119

    authors: Engel LS,Keifer MC,Thompson ML,Zahm SH

    更新日期:2001-11-01 00:00:00

  • Life-threatening heat-related illness with severe hyponatremia in an aluminum smelter worker.

    abstract::Heat stress is a recognized occupational hazard in aluminum smelter pot rooms. This is the report of an unusual and complex case of heat-related illness in an aluminum smelter worker. The 34-year-old male US worker developed life-threatening heat-related illness in August 2018, on his first day back at work after a 7-...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.23061

    authors: Wesdock JC,Donoghue AM

    更新日期:2019-12-01 00:00:00

  • Autoimmune antibodies and asbestos exposure: Evidence from Wittenoom, Western Australia.

    abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22863

    authors: Reid A,Franklin P,de Klerk N,Creaney J,Brims F,Musk B,Pfau J

    更新日期:2018-07-01 00:00:00

  • Dust content of lungs and its relationships to pathology, radiology and occupational exposure in Ontario hardrock miners.

    abstract:BACKGROUND:Autopsied lungs from 29 hard rock miners were investigated to determine the relationship of the dust content to pathology, radiology, and occupational exposure. METHODS:Each lung was divided horizontally into three sections. Pathological and radiological studies and chemical analyses were carried out on sam...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20589

    authors: Verma DK,Ritchie AC,Muir DC

    更新日期:2008-07-01 00:00:00

  • Artificial intelligence: Implications for the future of work.

    abstract::Artificial intelligence (AI) is a broad transdisciplinary field with roots in logic, statistics, cognitive psychology, decision theory, neuroscience, linguistics, cybernetics, and computer engineering. The modern field of AI began at a small summer workshop at Dartmouth College in 1956. Since then, AI applications mad...

    journal_title:American journal of industrial medicine

    pub_type: 历史文章,杂志文章,评审

    doi:10.1002/ajim.23037

    authors: Howard J

    更新日期:2019-11-01 00:00:00

  • Twenty-four-hour shift work, depressive symptoms, and job dissatisfaction among Japanese firefighters.

    abstract:BACKGROUND:The influence of a 24-hr shift-work burden on firefighters' mental health has not been fully investigated. The purpose of this study is to clarify the relationships between specific workload items among firefighters engaged in 24-hr shift work and job stress as estimated by the generic job-stress questionnai...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20571

    authors: Saijo Y,Ueno T,Hashimoto Y

    更新日期:2008-05-01 00:00:00

  • Humoral and cellular immune responses in asthmatic isocyanate workers: report of two cases.

    abstract::Two workers (23 and 28 years old) developed rhinitis and bronchial asthma after occupational contact with the isocyanate MDI. Positive skin prick test results for MDI-HSA and IgE antibodies to all isocyanate-HSA conjugates were obtained in both cases, and the inhalation challenge test with MDI produced immediate and l...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0274(199605)29:5<467::AID-AJIM5

    authors: Baur X,Seemann U,Marczynski B,Chen Z,Raulf-Heimsoth M

    更新日期:1996-05-01 00:00:00

  • Low back pain disability: relative costs by antecedent and industry group.

    abstract:BACKGROUND:Previous studies of workers' compensation claims for low back pain (LBP) have revealed that the preponderance of disability is borne by a fraction of cases. However, less is known regarding the influence of occupational factors on these extreme conditions. METHODS:Workers' compensation claims (n=107,867) fo...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(200005)37:5<558::aid-ajim1

    authors: Murphy PL,Courtney TK

    更新日期:2000-05-01 00:00:00

  • An epidemiological study of work with video screens and pregnancy outcome: II. A case-control study.

    abstract::A case-control study on work with video screen equipment during pregnancy has been made for three cohorts of women, identified with the aid of occupational codes in the census, linked to the Medical Birth Registry and a registry containing information on women hospitalized for spontaneous abortion. Five hundred and tw...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700090507

    authors: Ericson A,Källén B

    更新日期:1986-01-01 00:00:00

  • Dynamic thiol disulphide homeostasis in operating theater personnel exposed to anesthetic gases.

    abstract:BACKGROUND:The purpose of this study was to investigate the association between dynamic thiol/disulphide homeostasis and occupational exposure to volatile anesthetic gases in operating theater personnel. Decreased blood thiol levels and raised blood disulphide levels serve as biomarkers of oxidative stress. METHODS:We...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22764

    authors: Kozanhan B,Inanlı I,Deniz CD,Iyisoy MS,Neselioğlu S,Sahin O,Akin F,Tutar MS,Eren I,Erel O

    更新日期:2017-11-01 00:00:00

  • Cognitive effects of chronic exposure to lead and solvents.

    abstract:BACKGROUND:Occupational exposure to lead and solvents has declined steadily over the past 20 years, however, construction workers continue to be exposed to these neurotoxicants. The purpose of this study was to investigate the cognitive effects of chronic occupational exposure to lead and solvents. METHOD:Based on K-X...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.10287

    authors: Fiedler N,Weisel C,Lynch R,Kelly-McNeil K,Wedeen R,Jones K,Udasin I,Ohman-Strickland P,Gochfeld M

    更新日期:2003-10-01 00:00:00

  • Reported occupational respiratory diseases in three Spanish regions.

    abstract:BACKGROUND:In 2002, a voluntary registry of occupational respiratory diseases was initiated in the test phase in Asturias, Catalonia, and Navarre (Spain). Based on data from the fully implemented voluntary registry, we assessed the differences in the incidence and characteristics of the diseases reported in the three r...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20862

    authors: Orriols R,Isidro I,Abu-Shams K,Costa R,Boldu J,Rego G,Zock JP,other Members of the Enfermedades Respiratorias Ocupacionales y Medioambientales (EROM) Group.

    更新日期:2010-09-01 00:00:00

  • The Agricultural Health Study: factors affecting completion and return of self-administered questionnaires in a large prospective cohort study of pesticide applicators.

    abstract::Response rates were examined in a prospective epidemiologic study of individuals, mostly farmers, from Iowa and North Carolina seeking a pesticide applicator license during the period from 1994 through 1996. In the first year of enrollment 16,535 farmers (representing 77% of eligible farmer applicators) enrolled in th...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199702)31:2<233::aid-ajim1

    authors: Tarone RE,Alavanja MC,Zahm SH,Lubin JH,Sandler DP,McMaster SB,Rothman N,Blair A

    更新日期:1997-02-01 00:00:00

  • Risk factors for injury among construction workers at Denver International Airport.

    abstract:BACKGROUND:The Denver International Airport construction project provided a rare opportunity to identify risk factors for injury on a large construction project for which 769 contractors were hired to complete 2,843 construction contracts. Workers' compensation claims and payroll data for individual contracts were reco...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199808)34:2<113::aid-ajim3

    authors: Lowery JT,Borgerding JA,Zhen B,Glazner JE,Bondy J,Kreiss K

    更新日期:1998-08-01 00:00:00

  • Asbestos-associated cancers in the Ontario refinery and petrochemical sector.

    abstract::Asbestos has been widely used in the refinery and petrochemical sector. Mesothelioma has occurred among maintenance employees, and it was hypothesized that mesothelioma is a marker for exposures which might increase lung cancer risk. A death certificate-based case-control study of mesothelioma and lung cancer from 198...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0274(199611)30:5<610::AID-AJIM9

    authors: Finkelstein MM

    更新日期:1996-11-01 00:00:00

  • Acute traumatic injuries in underground bituminous coal miners.

    abstract::Using injury information from the 1986 Mine Safety and Health Administration database, and demographic information from a 1986 sample survey of the miner population, acute traumatic injury rates for male workers in underground bituminous coal mines were computed by age, current job experience, and total mine work expe...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700230304

    authors: Lee T,Anderson C,Kraus JF

    更新日期:1993-03-01 00:00:00

  • Contrasting associations of blood and semen lead concentrations with semen quality among lead smelter workers.

    abstract::While blood lead concentration has been inversely associated with indicators of reproductive health in occupationally exposed male workers, the utility of lead concentration in semen as an indicator of lead exposure to the male reproductive system has not been fully explored. Blood and semen lead concentrations from 8...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199811)34:4<464::aid-ajim2

    authors: Alexander BH,Checkoway H,Faustman EM,van Netten C,Muller CH,Ewers TG

    更新日期:1998-11-01 00:00:00

  • Asbestos-induced visceral pleural fibrosis reduces pulmonary compliance.

    abstract::To determine the nature of respiratory functional impairment caused by asbestos-induced visceral pleural fibrosis (VPF) and to discover which pulmonary physiological variable best reveals it, we examined 59 asbestos-exposed construction workers having asbestos-related changes on chest radiographs. Computed tomography ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700280306

    authors: Valkila EH,Nieminen MM,Moilanen AK,Kuusisto PA,Lahdensuo AH,Karvonen JI

    更新日期:1995-09-01 00:00:00

  • Issues in notification: reflections of a public health worker.

    abstract::The objectives of notification are to inform individuals of research results so that they can make informed choices regarding health care and risk reduction behaviors, and to inform workers and employers of results and recommendations in order to take actions to improve workplace health and safety. Many questions conf...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700230109

    authors: Rudolph L

    更新日期:1993-01-01 00:00:00

  • Severe lead poisoning in the plastics industry: a report of three cases.

    abstract:BACKGROUND:Lead stabilizers (e.g., lead sulfate, lead stearate) are common additives in plastics used in electrical devices. In 1997, three plastics compounders at one California company were severely lead-poisoned. METHODS:The poisonings were investigated by interviewing the workers, employer, and treating physician ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20123

    authors: Coyle P,Kosnett MJ,Hipkins K

    更新日期:2005-02-01 00:00:00

  • Zinc exposure in Chinese foundry workers.

    abstract:BACKGROUND:Inhalational exposure to zinc oxide fumes is associated with metal fume fever, a self-limited but very uncomfortable condition closely resembling influenza. Very little is known regarding the toxicokinetics of inhaled zinc, making the interpretation of zinc measurements in serum and urine problematic. METHO...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199906)35:6<574::aid-ajim4

    authors: Martin CJ,Le XC,Guidotti TL,Yalcin S,Chum E,Audette RJ,Liang C,Yuan B,Zhang X,Wu J

    更新日期:1999-06-01 00:00:00

  • Increased symptom reporting persists in 1990-1991 Gulf War veterans 20 years post deployment.

    abstract:BACKGROUND:Following the 1990-1991 Gulf War, Gulf War veterans (veterans) reported health symptoms more commonly than non-deployed groups. This article examines symptom persistence, incidence and prevalence 20 years on. METHODS:In 2000-2003 and 2011-2012, a 63-item symptom checklist was administered to 697 veterans an...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22490

    authors: Gwini SM,Forbes AB,Kelsall HL,Ikin JF,Sim MR

    更新日期:2015-12-01 00:00:00

  • Dupuytren's contracture and handwork: A case-control study.

    abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22736

    authors: Haines A,Levis C,Goldsmith CH,Kaur M,Duku E,Wells R,Walter SD,Rook C,Stock S,Liss G,Murphy J,Thoma A

    更新日期:2017-08-01 00:00:00