Abstract:
:Two workers (23 and 28 years old) developed rhinitis and bronchial asthma after occupational contact with the isocyanate MDI. Positive skin prick test results for MDI-HSA and IgE antibodies to all isocyanate-HSA conjugates were obtained in both cases, and the inhalation challenge test with MDI produced immediate and late asthmatic reactions. In the patch test and the stimulation assay of peripheral mononuclear blood cells, a specific sensitization to the diamine MDA (in both cases) and to further amines (in one case), as well as to hydrolysates of the respective diisocyanates, was seen, which appears to be independent of the IgE response to isocyanate-HSA conjugates. Our results offer evidence of IgE-mediated, as well as lymphocyte, responses induced by exposures to isocyanate products over several months or years.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Baur X,Seemann U,Marczynski B,Chen Z,Raulf-Heimsoth Mdoi
10.1002/(SICI)1097-0274(199605)29:5<467::AID-AJIM5subject
Has Abstractpub_date
1996-05-01 00:00:00pages
467-73issue
5eissn
0271-3586issn
1097-0274pii
10.1002/(SICI)1097-0274(199605)29:5<467::AID-AJIM5journal_volume
29pub_type
杂志文章abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22736
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Construction is a hazardous occupation, with Latino (Hispanic) workers at a greater risk for death than other ethnicities/races. Latinos accounted for over half of construction injuries involving days away from work in Nevada in 2006. METHODS:This study recruited 30 Latino construction workers from three So...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20735
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:To examine disparities between job control scores in Black and White subjects and attempt to discern whether self-rated low job control in Blacks may arise from structural segregation into different jobs, or represents individual responses to race-based discrimination in hiring or promotion. METHODS:Data fr...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22255
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Existing research suggests that workplace injuries can have significant economic and social consequences for workers; but there are no quantitative studies on complete populations. METHODS:The British Columbia Linked Health Database (BCLHD) was used to examine 1994 injured workers who lost work time due to ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20503
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:To compare the type, severity, cause, and cost of work-related injuries between Lebanese and non-Lebanese workers in insured workplaces in Lebanon. METHODS:A total of 4,186 claims and medical reports for 3,748 work-related injuries filed in 1998 at five major insurance companies were reviewed. RESULTS:Non-...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10246
更新日期:2003-08-01 00:00:00
abstract::Methods to collect epidemiologic data include, among other means, self-administered questionnaires and personal and telephone interviews. In some studies, these data collection methods are used simultaneously. However, little is known about the comparability of the data obtained, thus, the validity of pooling data. A ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199705)31:5<653::aid-ajim2
更新日期:1997-05-01 00:00:00
abstract::Following a work refusal at a plant manufacturing ice cream novelties in Ontario, we were asked to document cases of cumulative trauma disorders (CTDs) and carpal tunnel syndrome (CTS) in this workplace. There were 17 employees with possible hand and wrist problems identified from Workers Compensation Board (WCB) Form...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700220312
更新日期:1992-01-01 00:00:00
abstract::In a survey of chronic respiratory symptoms and airflow obstruction of a rural population aged 20-65 years, the effects of both farming and, in particular, the exposure to grain dust on the respiratory health of the people was examined. Of the 1,892 subjects (82% of the eligible population) studied, 924 were males and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700150103
更新日期:1989-01-01 00:00:00
abstract::Very sensitive and precise analytical methods for measuring total porphyrin excretion and the relative amounts of different porphyrins in urine are required in order to monitor the biological effects of porphyrinogenic substances in workers and the general population. Many analytical steps of a HPLC method for measuri...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040409
更新日期:1983-01-01 00:00:00
abstract::The objectives of notification are to inform individuals of research results so that they can make informed choices regarding health care and risk reduction behaviors, and to inform workers and employers of results and recommendations in order to take actions to improve workplace health and safety. Many questions conf...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230109
更新日期:1993-01-01 00:00:00
abstract::A series of 206 necropsies in Western Australia (WA) have had routine counts made of asbestos bodies in samples of lung tissue using conventional light microscopy. Thirty-two cases had worked in the asbestos industry at Wittenoom, WA and (log) counts of asbestos bodies in their lung tissue correlated well with estimat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280405
更新日期:1995-10-01 00:00:00
abstract::Skin symptoms of "yusho" and their change thereafter are described. In the early stage, skin eruptions were the most prominent and impressive features of yusho. Acneiform eruptions and pigmentation were most conspicuous. With the passage of time, there is some improvement and most patients now have few eruptions, exce...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Blood histamine levels were measured by the bioassay of histamine (on an isolated strip of guinea pig ileum) in workers exposed to cotton dust in a textile mill in Ahmedabad. Byssinotic subjects showed very high levels of blood histamine as compared to nonbyssinotic and control subjects. The blood histamine levels wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120409
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Death certificates contain a box labeled "Injury at Work" which is to be marked "Yes" for all fatal occupational injuries. The accuracy of this box in Michigan is not fully characterized. METHODS:The accuracy of the Injury at Work box on the Michigan death certificate was compared to deaths identified from ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23100
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:The aims of this study were to compare job demand-control (JDC) and effort-reward imbalance (ERI) models in examining the association of job stress with work-related musculoskeletal symptoms and to evaluate the utility of a combined model. METHODS:This study analyzed cross-sectional survey data obtained fro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22274
更新日期:2014-02-01 00:00:00
abstract::We conducted a comparative study of pulmonary dysfunction among workers who were exposed to silica, asbestos, or coalmine dust. The results showed that all three groups of dust-exposed workers, even those without radiographic signs of pneumoconiosis, had decreased spirometric parameters and diffusing capacity (DLco) i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199705)31:5<495::aid-ajim2
更新日期:1997-05-01 00:00:00
abstract::A 5-year prospective analysis tests the hypothesis that coal miners who have impaired respiratory health also experience greater numbers of disability days due to occupational injury. Occupational and respiratory health information collected for the period 1977 through 1981 by the National Institute for Occupational S...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070409
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Occupational exposures may be related to the development of brain cancer. The objective was to estimate occupational-specific risk of gliomas and meningiomas among Swedish men and women gainfully employed in 1970 over the period 1971-1989, and the influence of occupational exposure to chemical substances. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10107
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:A beryllium materials manufacturer is conducting a limited pilot program that offers testing for HLA-DP beta 1E69 with genetic counseling through a third party to applicants for employment. An important consideration in this regard is the prevalence of this marker in the general population, and its consequen...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10072
更新日期:2002-06-01 00:00:00
abstract::Attitudes of occupational health care professionals toward smoking and their activity to address smoking issues were investigated by a questionnaire survey. Data were also collected on employees' exposure to environmental tobacco smoke and on smoking policies that existed in workplaces. Questionnaires were mailed to a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199807)34:1<73::aid-ajim10
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:The Sheet Metal Occupational Health Institute Trust (SMOHIT) was formed in 1985 to examine the health hazards of the sheet metal industry in the U.S. and Canada through an asbestos disease screening program. A study of mortality patterns among screening program participants was undertaken. METHODS:A cohort ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20725
更新日期:2009-08-01 00:00:00
abstract::Epidemiological investigation involving historical cohorts requires reconstruction of individual cohort member exposures during the period of study. However, past approaches to exposure assessment by industrial hygienists were characterized by different professional expectations for air sampling, and different orienta...
journal_title:American journal of industrial medicine
pub_type: 历史文章,杂志文章
doi:10.1002/ajim.4700210114
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compile nationally representative statistics describing inpatient hospital care for patients with work-related injuries and illnesses covered under workers' compensation (WC) insurance in the United States. METHODS:Three years of data (1997-1999) from the Nationwide Inpatient Sa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10273
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Hotel room cleaners have physically demanding jobs that place them at high risk for shoulder pain. Psychosocial work factors may also play a role in shoulder pain, but their independent role has not been studied in this group. METHODS:Seventy-four percent (941 of 1,276) of hotel room cleaners from five Las ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20832
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group. METHODS:An elec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1125
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Self-reported work histories can be critical for both epidemiologic and clinical purposes. However, the complexity of some work histories, such as those of migrant farm workers, can hamper recall, resulting in inaccurate reporting. Memory aids may reduce such error. This study assesses the reliability of wor...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1119
更新日期:2001-11-01 00:00:00
abstract::In this article the material collected for a case-control study is analyzed in order to evaluate the existence of relationships between organic solvent exposure and the entitlement to disability benefits due to neuropsychiatric disorders. Questionnaires were used to collect information on 252 cases receiving compensat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700160610
更新日期:1989-01-01 00:00:00
abstract::Recent studies suggest that semiconductor workers have an increased incidence of work-related illness. Semiconductor manufacturing is a chemically intensive industry involving many potentially hazardous operations. As this industry moves into new geographic areas, health care professionals will be asked to evaluate me...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700110209
更新日期:1987-01-01 00:00:00
abstract::Limitations on the use of full halogenated chlorofluorocarbons (CFCs) may create occupational environmental problems. These are currently largely unknown, because the toxicology of most CFC substitutes is unknown. Therefore, toxicity testing of CFC substitutes is necessary, and this can best be done before their use c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700190615
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Few epidemiologic studies have addressed the exposure-response relationships between work activities and symptomatic knee osteoarthritis (OA). This analysis used data from a national survey and ergonomists' ratings to address this issue. METHODS:Interview and knee X-ray data were obtained from the Third Nat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20512
更新日期:2008-01-01 00:00:00