Asbestos-related pleural disease due to tremolite associated with progressive loss of lung function: serial observations in 123 miners, family members, and residents of Libby, Montana.

Abstract:

BACKGROUND:The community of Libby, Montana has recently been the focus of national attention secondary to widespread amphibole contamination associated with vermiculite mining and processing. METHODS:Patients who had occupational and non-occupational exposure to amphibole asbestos in Libby, Montana were evaluated for progressive loss of pulmonary function. RESULTS:Of the 123 patients evaluated, 94 demonstrated average age-corrected accelerated loss per year of vital capacity at 3.2%, total lung capacity (TLC) 2.3%, and DLCO 3.3%. All patients all had predominantly pleural changes with minimal to no interstitial disease. CONCLUSIONS:The study demonstrates a progressive loss of pulmonary function in patients exposed to tremolite asbestos.

journal_name

Am J Ind Med

authors

Whitehouse AC

doi

10.1002/ajim.20053

subject

Has Abstract

pub_date

2004-09-01 00:00:00

pages

219-25

issue

3

eissn

0271-3586

issn

1097-0274

journal_volume

46

pub_type

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