Abstract:
:To confirm the relationship between exposure to coal tar pitch volatiles and bladder cancer among primary aluminum production workers, we carried out a case-control study among blue-collar workers who had worked more than 1 year between 1950-1979 in a major plant using mostly the Soderberg process in the Province of Québec. Cases of bladder cancer (ICD code 188) diagnosed between 1970-1979 (n = 69) were mostly included in a previously reported study. To these were added cases diagnosed between 1980-1988 (n = 69). Each case was matched to three controls on date of birth, date of hiring, and length of service at the company. Smoking habits were assessed from the medical records at the company. Benzene-soluble matter (BSM) and benzo(a)pyrene (BaP) were used as indicators of environmental exposure to coal tar pitch volatiles in the workplace. The estimated risk for current smokers was 2.63 (95% C.I. 1.29-5.37). Estimates of risk by occupational exposure were adjusted for smoking. Men who had worked in the Soderberg potrooms were at higher risk of developing the disease, the risk increasing with the time spent in these departments. Similarly, a strong association between risk and cumulative exposure to BSM or to BaP was observed. The risks associated with cumulative exposure to BSM (mg/m3-years) and to BaP (microgram/m3-years) were described with mathematical models. Using a linear model (1 + bx) and lagging 10 years before the diagnosis, BaP cumulative exposure was a better indicator of risk than BSM cumulative exposure. The risk for each year of exposure to BaP at a concentration of 1 microgram/m3 increased by 1.7% (0.8%-3.2%). Using the same model for BSM, a worker exposed to the current threshold limit value of 0.2 mg/m3 for 40 years will sustain a risk of 2.22 (1.56-3.48). Comparison of risks according to different periods of diagnosis (1970-1979 vs. 1980-1988) did not reveal any significant temporal changes on risk estimates.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Tremblay C,Armstrong B,Thériault G,Brodeur Jdoi
10.1002/ajim.4700270303subject
Has Abstractpub_date
1995-03-01 00:00:00pages
335-48issue
3eissn
0271-3586issn
1097-0274journal_volume
27pub_type
杂志文章abstract::Basophilic stippling of red blood cells (BSC) has been noted in lead intoxication since 1899 and has been considered a classic laboratory sign of lead poisoning since that time. BSC are inclusions of aggregated ribosomes found only in the red blood cells and may be confused with siderotic (iron) granules. Heinz Bodies...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700050409
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Harvesting of blueberries is associated with musculoskeletal injury. This study assessed the effects of several alternative designs of the harvesting rake. METHODS:A community-based work team selected rake design for intervention and pilot tested potential design modifications to the blueberry harvesting ra...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20554
更新日期:2008-04-01 00:00:00
abstract::A joint study on effects of formaldehyde exposure in industrial populations by the National Cancer Institute and the Formaldehyde Institute, Inc. (Blair et al. [1986]: J Natl Cancer Inst 76: 1071-1084; Blair and Stewart [1989]: J Occup Med 31: 881, Blair et al. [1990]: Am J Ind Med 17:683-700) reported no significant ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250413
更新日期:1994-04-01 00:00:00
abstract::To elucidate the effect of low level lead (Pb) exposure on somatic and autonomic peripheral nerve functions in ceramic painters, 58 males and 70 females, aged 29-75 years (mean 53.3 years), with lead concentrations in blood (Pb-B) ranging from 2.1 to 69.5 micrograms/dl (geometric mean 13.3 micrograms/dl), were examine...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199605)29:5<547::AID-AJIM1
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:OSHA regulations require that workers receive medical clearance prior to respirator use, and recently, a detailed questionnaire has been provided to assist with this purpose. However, there are limited published data on the sensitivity and specificity of self-administered questionnaires for identifying indiv...
journal_title:American journal of industrial medicine
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0274(199904)35:4<395::aid-ajim1
更新日期:1999-04-01 00:00:00
abstract::Fertility among men working in semiconductor manufacturing during 1984-89 was assessed in a 1990-91 cross-sectional study of eight companies. Men working in wafer fabrication rooms (fabs) (n = 241, 165 births) were compared to men in nonfabrication (nonfab) jobs (n = 447, 300 births). Results showed that 17% of fab me...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280618
更新日期:1995-12-01 00:00:00
abstract::A case-control study on work with video screen equipment during pregnancy has been made for three cohorts of women, identified with the aid of occupational codes in the census, linked to the Medical Birth Registry and a registry containing information on women hospitalized for spontaneous abortion. Five hundred and tw...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700090507
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Children living or working on New York farms face unique hazards and experience on-farm injuries related to these. The New York Community Partners for Healthy Farming (CPHF) surveillance provided a unique source of information for analyses of risk factors-particularly age-for these events. METHODS:Agricultu...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10062
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Exposure to silica dust is considered to be one of etiological factors of antineutrophil cytoplasmic antibodies (ANCA) -associated vasculitis (AAV). METHODS:Subjects exposed to silica dust in Central Bohemia and followed in the Department of Occupational Medicine, Charles University, were selected for study...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20327
更新日期:2006-07-01 00:00:00
abstract::Injury is the leading cause of death in adolescence, with the highest rates for 15- to 19-year-olds, an age span also marked, for many, by entry into the workforce. Occupational injuries affecting youth occur in the context of the larger problem of injury affecting children and adolescents. An understanding of the bro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240307
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Acoustic neuroma is the intracranial tumor subtype showing the highest relative risk in relation to ionizing radiation but other environmental risk factors are largely unknown. This study was performed to investigate the effect of power frequency magnetic fields. METHOD:A total of 793 cases between 1987 and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20251
更新日期:2006-02-01 00:00:00
abstract::This Working Group was assembled to review and evaluate methods currently used to estimate work site exposures to biological agents and to present recommendations on suitable measurement strategies. The current state of exposure assessment was evaluated for environments with organic dust including agriculture, compost...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20066
更新日期:2004-10-01 00:00:00
abstract::In adults, lead toxicity is most commonly caused by occupation in a lead industry. Whereas lead toxicity has been described in workers who are involved in bridge rehabilitation, as of this date there has been no systematic evaluation published regarding the conditions responsible for lead toxicity in ironworkers. This...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199711)32:5<540::aid-ajim1
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1042
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Because of reported associations of psychosocial factors and computer related musculoskeletal symptoms, we investigated the effects of a workplace psychosocial factor, reward, in the presence of over-commitment, on trapezius muscle activity and shoulder, head, neck, and torso postures during computer use. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22192
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The roles of age, length of service and job in various work-related injury types are unknown and deserve investigations among female workers. This study assessed their roles in the occurrence of injury. METHODS:Three-year prospective study of all 22,952 permanently employed women at the French national rail...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22259
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:In the city of Petrópolis, Brazil, artisans carve souvenirs from a variety of silica-containing minerals. The finding of pulmonary massive fibrosis in one of the workers motivated an investigation of the prevalence of silicosis in this group. METHODS:Between January 2000 and June 2002, a cross-sectional stu...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10331
更新日期:2004-02-01 00:00:00
abstract::Several research projects on work-related respiratory diseases have been conducted in Finland. One of the largest, "Farmers' Occupational Health Programme," was conducted by the Social Insurance Institution of Finland during 1973-1983 in cooperation with Kuopio Regional Institute of Occupational Health and the Nationa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180305
更新日期:1990-01-01 00:00:00
abstract::The association between lead absorption and objective psychological performance tests in five groups with different levels of lead absorption was studied in the following groups: (1) a control, non-lead-exposed group; (2) cable splicers, (3) cable manufactures, and (4) secondary lead smelter workers. The following per...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700010320
更新日期:1980-01-01 00:00:00
abstract::We reviewed 8,502 deaths registered at the Salt River state mortuary, Cape Town (medical examiner records) for an 18-month period (1/1/90-6/30/91). When fatal occupational injuries located from this data source were matched with the records of the occupational safety inspectorate of the Department of Manpower, it was ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260409
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:The Limulus amebocyte lysate (LAL) assay may underestimate endotoxins because only soluble endotoxins are determined. The solubility of endotoxins was, therefore, studied in two species of Gram-negative bacteria. METHODS:Cultures were grown in serum broth, cells were harvested by centrifugation and washed i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20089
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:The amount of information about hazardous agents in the workplace exceeds the capacity of human memory. There is a need to accurately represent or map this scientific knowledge for digital storage and retrieval. METHODS:A relational database of hazardous chemicals and occupational diseases was constructed b...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20578
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Neck pain is a prevalent musculoskeletal condition among workers in the United States. This study explores a set of workplace psychosocial and organization-related factors for neck pain. METHODS:Data used for this study come from the 2010 National Health Interview Survey which provides a representative samp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22602
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Work-related mortality is a relatively new concept which aims to widen occupational health and safety; to take into account not only recognized fatal occupational accidents and diseases but also other work-related deaths. Few countries in the world have a register for work-related diseases. METHODS:Estimate...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20411
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tubercul...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23066
更新日期:2020-01-01 00:00:00
abstract::Since 1988, the National Institute for Occupational Safety and Health (NIOSH) has notified workers who were subjects in occupational epidemiology studies of the study findings ("worker notification"). This paper describes seven notifications and the worker's reactions to them. The chemicals of interest in the studies ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270403
更新日期:1995-04-01 00:00:00
abstract::Roll-over protective structures (ROPS) on farm tractors could significantly reduce the rate of fatal occupational injury on farms, but comparatively few tractors have them. Many of the policy discussions have focused on trying to identify the percentage of tractors that do not have ROPS, even though such a focus proba...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199610)30:4<447::AID-AJIM1
更新日期:1996-10-01 00:00:00
abstract::The objectives of this study were 1) to summarize in a clinically meaningful way information on occupational risk factors for carpal tunnel syndrome (CTS), and 2) to test a questionnaire on risk factors that could be used by physicians with their patients. For the two objectives, a systematic literature review was per...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0274(199803)33:3<224::aid-ajim3
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Engineering or administrative methods are often insufficient or impractical to control exposure to chemicals in anatomy laboratories. This study explored the feasibility of wearing one or a combination of respirators and goggles used as personal protective equipment (PPE) to control exposure in one such labo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10180
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Continuous increase in male incidence of malignant mesothelioma of the pleura (MMP) despite the drop of asbestos production since 1980 in Québec motivated this study aiming to assess when the rates of MMP will decline. METHODS:Age-standardized rates and trends were estimated over the 1984-2007 period by sex...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22442
更新日期:2015-05-01 00:00:00