Abstract:
:Parenteral administration of antigen induces in the earthworms Lumbricus terrestris and Eisenia foetida the formation of antigen-binding protein. Labelled antigen was efficiently digested in the coelomic fluids of both species since the total amount of radioactivity in the coelomic fluids decreased. Antigen internalized in the free coelomocytes of both species was present in a TCA-precipitable form, although the decline of total radioactivity was higher than in the coelomic fluid, indicating that the TCA-nonprecipitable fragments are rapidly released from coelomocytes into the coelomic fluid. Within the first 24 h after administration, labelled antigen was detected throughout all tissues except for the epidermis and cuticle, and after 4 days it was found in the chloragogenic tissue around the gut, dorsal vein and typhlosole.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Rejnek J,Tucková L,Síma P,Bilej Mdoi
10.1016/0165-2478(93)90044-3subject
Has Abstractpub_date
1993-05-01 00:00:00pages
131-5issue
2eissn
0165-2478issn
1879-0542pii
0165-2478(93)90044-3journal_volume
36pub_type
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