Folinic acid does not mobilize hemopoietic progenitors following repeated consolidation chemotherapy for acute leukemia.

abstract：:Modern techniques of mechanical hemapheresis have made it possible to selectively remove vast quantities of lymphocytes and plasma immunoglobulins, and the concentration of these substances in donor blood can fall below the normal range. It is feared that this may lead to immunosuppression; a condition associated in s...

journal_title：Journal of clinical apheresis

authors： Strauss RG

更新日期：1984-01-01 00:00:00

abstract：INTRODUCTION:Algorithms have been developed to predict the platelet yield after apheresis from the donor's data, as well as the effect on the blood cell count, to extract an acceptable platelet number without affecting the donor. However, the evaluation of these algorithms has not been widely reported. This study aimed...

journal_title：Journal of clinical apheresis

authors： Cienfuegos-Pecina E,Ayala-De la Cruz S,Leal-Nava ER,Pérez-Olvera JA,Llaca-Díaz JM,Avilés-Rodríguez LE,Pérez-Chávez F,Díaz-Chuc EA

更新日期：2020-10-05 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) can occur following exposure to heparin and is characterized by thrombocytopenia with increased risk for thrombosis. This condition is mediated by formation of immunoglobulin G antibodies against platelet factor 4/heparin complexes that can subsequently lead to platelet activatio...

journal_title：Journal of clinical apheresis

authors： Raval JS,Park YA,Perjar I,Mazepa MA,Vincent BG,Ma AD,Rollins-Raval MA

更新日期：2020-01-01 00:00:00

abstract：:Lipid-apheresis (LA) is thought to improve microcirculation. However, limited data are available on the effects on peripheral microcirculation. We investigated upper limb microcirculation of 22 patients undergoing regular LA on a weekly basis before and after LA. Using standardized semiquantitative scales, we analyzed...

journal_title：Journal of clinical apheresis

authors： Rossenbach J,Mueller GA,Lange K,Armstrong VW,Schmitto JD,Hintze E,Helfmann J,Konstantinides S,Koziolek MJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Autologous stem cell transplantation (auto-SCT) is a treatment approach in non-Hodgkin lymphoma (NHL) patients. The options for mobilization of CD34+ cells to support high-dose therapy are granulocyte-colony stimulating factors (G-CSFs) alone or after chemotherapy. Limited data exist on the efficacy of lipeg...

journal_title：Journal of clinical apheresis

authors： Partanen A,Turunen A,Valtola J,Vasala K,Ågren L,Penttilä K,Pyörälä M,Kuittinen T,Mäntymaa P,Pelkonen J,Jantunen E,Varmavuo V

更新日期：2020-08-01 00:00:00

abstract：:We describe the case of a 24 year old male with severe fistulating Crohn's disease who failed mutliple modalities of medical and surgical therapy. We present objective and subjective evidence of disease remission after induction and maintenance treatment with leukocyte apheresis. This is the first described case of su...

journal_title：Journal of clinical apheresis

authors： Tate D,Cairnes V,Valori R,Makins R

更新日期：2014-06-01 00:00:00

abstract：:Until recently, the collection of peripheral blood progenitor cells (PBPC) has been semi-automated by using the COBE Spectra, with the operator manually maintaining the position of the white cells being collected. The COBE Spectra Version 6.0 apheresis device offers the user an automated program for the collection of ...

journal_title：Journal of clinical apheresis

authors： Wilke R,Brettell M,Prince HM,Wolf M,McKenna R,Serpell E,Molloy M,Stevens H,Quinn M,Gates P,Chapple P

更新日期：1999-01-01 00:00:00

abstract：:Leukemic-dendritic cells (leukemic-DCs) have certain limitations, which include difficult generation in 30-40% of patients, and low levels of expression of several key molecules. Therefore, an alternative approach using monocyte-derived DCs pulsed with tumor antigens is required. We investigated the possibility of imm...

journal_title：Journal of clinical apheresis

authors： Lee JJ,Park MS,Park JS,Kang HK,Kim SK,Nguyen Pham TN,Zhu XW,Cho D,Nam JH,Kim YJ,Rhee JH,Chung IJ,Kim HJ

更新日期：2006-10-01 00:00:00

abstract：:The aim of this study was to analyze the impact of various donor and machine parameters on PLT yield in 127 PLT apheresis procedures, to optimize PLT yield achieving clinical and economic advantages. One hundred and twenty-seven apheresis procedures were analyzed. Age, gender, volume processed, Hb, and PLT precounts w...

journal_title：Journal of clinical apheresis

authors： Enein AA,Hussein EA,El Shafie S,Hallouda M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In organ transplantation, apheresis is frequently used for removal of anti-HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi-selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to reach post-treatment objectives is also unknown. ...

journal_title：Journal of clinical apheresis

authors： Jambon F,Merville P,Guidicelli G,Taton B,De Précigout V,Couzi L,Moreau K,Visentin J

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Hyperleukocytosis is commonly seen in acute and chronic leukemias. Therapeutic leukocytapheresis using an automatic cell separator can help to achieve prompt leukoreduction to reduce the rate of thrombotic events and early mortality as well as to prevent tumor lysis syndrome. AIM:In this study, we report a ...

journal_title：Journal of clinical apheresis

authors： Nguyen TH,Bach KQ,Vu HQ,Nguyen NQ,Duong TD,De Reys S,Wheeler J

更新日期：2020-04-01 00:00:00

abstract：:Mobilized stem cells in the peripheral blood (PB) must be efficiently harvested at the appropriate time before autologous PB stem cell (PBSC) transplantation. Enumeration of CD34+ cells in the PB before apheresis predicts the number of PBSCs that can be collected, but the cytometric techniques used are complex and exp...

journal_title：Journal of clinical apheresis

authors： Mitani N,Yujiri T,Tanaka Y,Tanaka M,Fujii Y,Hinoda Y,Tanizawa Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Perioperative therapeutic plasma exchange in patients with cardiovascular diseases poses several challenges, including alterations in intravascular volume, serum electrolytes, the coagulation cascade, and drug pharmacokinetics. METHODS:This review article summarizes different indications of plasma exchange ...

journal_title：Journal of clinical apheresis

authors： Kanellopoulou T,Kostelidou T

更新日期：2019-08-01 00:00:00

abstract：:The infusion of high-dose (275 mg/kg body weight) immune globulin intravenous (IGIV) after 466 plasma exchanges in 64 patients with autoimmune disease was studied. Side effects occurred during 15% of IGIV infusions. For the most part they were transient and mild, and could be controlled by slowing the infusion rate. T...

journal_title：Journal of clinical apheresis

authors： Dau PC

更新日期：1983-01-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease treated successfully with plasma exchange. Jehovah's Witnesses whose religious beliefs preclude them from accepting plasma exchange may require alternative forms of therapy. We report a case of one such patient who presented with TTP, whom we succ...

journal_title：Journal of clinical apheresis

authors： Dabak V,Kuriakose P,Raman S

更新日期：2007-01-01 00:00:00

abstract：:The practice of transfusing ABO-incompatible platelets, driven primarily by concerns about inventory management, has been considered generally safe because the accompanying plasma is usually diluted in the recipient's total blood volume. However, if the platelet product contains a large volume of plasma or a high conc...

journal_title：Journal of clinical apheresis

authors： Sapatnekar S,Sharma G,Downes KA,Wiersma S,McGrath C,Yomtovían R

更新日期：2005-12-01 00:00:00

abstract：:In-line leukocyte reduction filters (LRF) are available for use with an automated plateletpheresis (PPH) system. Initially, 62% of PPH units produced with such a filter (LRF6, N = 29) had postfiltration (POF) white blood cell (WBC) counts < 5 x 10(6), with a mean POF WBC of 42 x 10(6). In an attempt to decrease POF WB...

journal_title：Journal of clinical apheresis

authors： Drew MJ,Hodges J

更新日期：1995-01-01 00:00:00

abstract：:The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related co...

journal_title：Journal of clinical apheresis

authors： Kiprov DD,Lippert R,Sandstrom E,Jones FR,Cohen RJ,Abrams D,Busch DF

更新日期：1985-01-01 00:00:00

abstract：:For many years dextran sulfate adsorption (DSA) treatment of separated plasma has been an established technology for low-density lipoprotein (LDL)-elimination. Recently a system for the treatment of whole blood based on DSA was introduced into clinical practice. To further characterize DSA treatment of whole blood, th...

journal_title：Journal of clinical apheresis

authors： Julius U,Parhofer KG,Heibges A,Kurz S,Klingel R,Geiss HC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Autoimmune disorders and neurodegenerative disorders take a physical and emotional toll on patients that undergo therapeutic plasma exchange (TPE) treatments. Previous literature has shown that these patients may feel a greater sense of self-burden. Motivational Interviewing (MI) is a technique used in vario...

journal_title：Journal of clinical apheresis

authors： Dill R,Olson DM,Session-Augustine N,Mariani D,Stutzman SE

更新日期：2018-10-01 00:00:00

abstract：:Because the administration of hematopoietic growth factors and the use of stem cell support often fails to alleviate the neutropenic phase induced by cytotoxic drugs, several investigators have attempted to expand ex vivo hematopoietic progenitors for clinical use. These attempts have clearly shown that the cultured c...

journal_title：Journal of clinical apheresis

authors： Estrov Z,Huh YO,Ginsberg CF,Harris D,Van Q,Mirza NQ,Talpaz M,Korbling M

更新日期：2002-01-01 00:00:00

abstract：:Peripheral blood stem cells (PBSC) reinfusion appears to hasten hematologic reconstitution following myeloablative therapy. While procurement of PBSC adds apheresis procedures, rapid engraftment could decrease the demand for platelet transfusions. To determine the impact of PBSC collection on workload in our apheresis...

journal_title：Journal of clinical apheresis

authors： Ghalie R,McLeod B,Richman C,Valentino L,Manson S,Netols C,Kaizer H

更新日期：1992-01-01 00:00:00

abstract：INTRODUCTION:Limited data are available describing indications for and outcomes of therapeutic plasma exchange (TPE) in cardiac transplantation. METHODS:In a retrospective study of patients who underwent cardiac transplantation at Duke University Medical Center from 2010 to 2014, we reviewed 3 TPE treatment patterns: ...

journal_title：Journal of clinical apheresis

authors： Onwuemene OA,Grambow SC,Patel CB,Mentz RJ,Milano CA,Rogers JG,Metjian AD,Arepally GM,Ortel TL

更新日期：2018-08-01 00:00:00

abstract：:Sickle cell disease (SCD) patients are prone to develop complications that include stroke, acute chest syndrome, and other crises. Some of these complications require chronic transfusion therapy or red cell exchange (RCE), either for therapeutic or prophylactic reasons. Due to a discrepancy of red cell antigens betwee...

journal_title：Journal of clinical apheresis

authors： Sarode R,Altuntas F

更新日期：2006-12-01 00:00:00

abstract：:Extracorporeal photopheresis (ECP) has been shown to be clinically effective in the treatment of many T cell-mediated conditions. ECP's mechanism of action includes the induction of apoptosis and the release of pro-inflammatory cytokines. Recently, we have observed early lymphoid apoptosis, detectable immediately post...

journal_title：Journal of clinical apheresis

authors： Bladon J,Taylor P

更新日期：2002-01-01 00:00:00

abstract：:We have reviewed our initial experience with a program of concurrent collection of plasma (CCP) during plateletpheresis, which was instituted to increase the number of units of fresh frozen plasma produced by our hospital-based donor service. Sixty percent of eligible donors (1,006 of 1,682) participated in CCP, and 2...

journal_title：Journal of clinical apheresis

authors： Burger SR,Thomas BT,Grishaber JE

更新日期：1994-01-01 00:00:00

abstract：:Inadvertent hypothermia due to massive infusion of stored blood can be prevented by pretransfusion warming. One approach is the heating of individual packs by means of electromagnetic conduction, which is a method safely used over the last 25 years. The prototype instrument, which has now been re-engineered, can effec...

journal_title：Journal of clinical apheresis

authors： Harrison GG,Bird AR,Jacobs P,Coghlan P,Byrne MJ,Ozinsky J,Besseling JL

更新日期：1992-01-01 00:00:00

abstract：:Excess free iodide in the blood (ingested or injected) may cause thyrotoxicosis in patients at risk. Iodinated contrast solutions contain small amounts of free iodide and may be of significance for patients affected by Graves' disease, multinodular goiter or living in areas of iodine deficiency. Herein, we report a 57...

journal_title：Journal of clinical apheresis

authors： Pasimeni G,Caroli F,Spriano G,Antonini M,Baldelli R,Appetecchia M

更新日期：2008-01-01 00:00:00

abstract：:Thrombopoietin (c-Mpl ligand) is the hematopoietic growth factor that is responsible for regulating the production of platelets from bone marrow megakaryocytes. This approximately 90 kd protein has recently been isolated and is comprised of an erythropoietin domain that is approximately 50% homologous to erythropoieti...

journal_title：Journal of clinical apheresis

authors： Kuter DJ

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Wilson's disease is a rare autosomal recessive genetic disorder that results in accumulation of copper in the liver, brain, cornea and kidney. Therapeutic plasma exchange (TPE) has been used to remove copper and provide a bridge to liver transplantation. We report here the collective experiences through the ASF...

journal_title：Journal of clinical apheresis

authors： Pham HP,Schwartz J,Cooling L,Hofmann JC,Kim HC,Morgan S,Pagano MB,Schneiderman J,Winters JL,Yamada C,Wong EC,Wu Y

更新日期：2016-02-01 00:00:00