Comparison of COBE Spectra software version 4.7 PBSC and version 6.0 auto PBSC program.

abstract：:This study chronicles leukocyte- and erythrocyte-depleted platelet concentrate collection by a dual stage channel in which three variables: 1) donor peripheral blood platelet concentration, 2) total blood processed, and 3) collection volume were statistically correlated with platelet yield as determined by a multiple ...

journal_title：Journal of clinical apheresis

authors： Hester JP,Kellogg RM,Mulzet AP,Freireich EJ

更新日期：1985-01-01 00:00:00

abstract：:In-line leukocyte reduction filters (LRF) are available for use with an automated plateletpheresis (PPH) system. Initially, 62% of PPH units produced with such a filter (LRF6, N = 29) had postfiltration (POF) white blood cell (WBC) counts < 5 x 10(6), with a mean POF WBC of 42 x 10(6). In an attempt to decrease POF WB...

journal_title：Journal of clinical apheresis

authors： Drew MJ,Hodges J

更新日期：1995-01-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a recognized complication of malignant hypertension (HTN). Such patients have blood pressures > or = 200/140 mmHg but the condition is defined by the presence of papilledema and is frequently complicated by acute renal failure. Here we report two patients with severe HTN (systolic >...

journal_title：Journal of clinical apheresis

authors： Egan JA,Bandarenko N,Hay SN,Paradowski L,Goldberg R,Nickeleit V,Brecher ME

更新日期：2004-01-01 00:00:00

abstract：:We have reviewed our initial experience with a program of concurrent collection of plasma (CCP) during plateletpheresis, which was instituted to increase the number of units of fresh frozen plasma produced by our hospital-based donor service. Sixty percent of eligible donors (1,006 of 1,682) participated in CCP, and 2...

journal_title：Journal of clinical apheresis

authors： Burger SR,Thomas BT,Grishaber JE

更新日期：1994-01-01 00:00:00

abstract：:The removal of specific antibody in experimental animals has been reported to result in a subsequent increase in antibody to levels equal to (rebound) or exceeding those existing prior to removal (overshoot). Anecdotal reports suggest that rebound antibody synthesis after plasmapheresis may occur in humans with autoim...

journal_title：Journal of clinical apheresis

authors： Nasca TJ,Muder RR,Thomas DB,Schrecker JC,Ruben FL

更新日期：1990-01-01 00:00:00

abstract：:Mobilized stem cells in the peripheral blood (PB) must be efficiently harvested at the appropriate time before autologous PB stem cell (PBSC) transplantation. Enumeration of CD34+ cells in the PB before apheresis predicts the number of PBSCs that can be collected, but the cytometric techniques used are complex and exp...

journal_title：Journal of clinical apheresis

authors： Mitani N,Yujiri T,Tanaka Y,Tanaka M,Fujii Y,Hinoda Y,Tanizawa Y

更新日期：2011-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) recurs in 30% of renal allograft transplants with graft loss in half of the cases. A humoral factor may be implicated. We report on the use of therapeutic plasma exchange (TPE) in 11 patients with recurrent FSGS post transplantation. Medical records from 1989-2000 were reviewe...

journal_title：Journal of clinical apheresis

authors： Shariatmadar S,Noto TA

更新日期：2002-01-01 00:00:00

abstract：:One of the most serious problems in applying leukapheresis to human infants is the large extracorporeal blood volume (ECV), resulting in substantial loss of platelets and red blood cells (RBCs). In this study, we developed a safe and effective modified procedure to collect peripheral blood stem cells (PBSCs) from rhes...

journal_title：Journal of clinical apheresis

authors： Ageyama N,Kimikawa M,Eguchi K,Ono F,Shibata H,Yoshikawa Y,Terao K

更新日期：2003-01-01 00:00:00

abstract：:Therapeutic plasma exchange (TPE) is an increasingly utilized immunosuppressive adjunct for treatment of antibody-mediated rejection (AMR) following organ transplantation. TPE works through removal of donor-specific HLA antibodies (DSAs) in the recipient's plasma. However, there is no clear laboratory measure evaluati...

journal_title：Journal of clinical apheresis

authors： Jackups R Jr,Canter C,Sweet SC,Mohanakumar T,Morris GP

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Myeloid-derived leucocytes, a major source of inflammatory cytokines, play an important role in the exacerbation of ulcerative colitis (UC). Selective depletion of myeloid leucocytes by adsorptive granulomonocytapheresis (GMA) with an Adacolumn should alleviate inflammation and promote remission. However, th...

journal_title：Journal of clinical apheresis

authors： Li N,Mao J,Tang H,Zhu L,Tan X,Bi J,Wu H,Chen X,Wang Y

更新日期：2020-08-01 00:00:00

abstract：:Blood products are frequently required immediately prior to, during, or just after an apheresis procedure. Transfusion-related acute lung injury (TRALI) is now the leading cause of transfusion-related mortality, surpassing ABO-incompatible hemolytic reactions. The reported incidence of TRALI varies but is estimated at...

journal_title：Journal of clinical apheresis

authors： Cruz J,Skipworth E,Blue D,Waxman D,McCarthy L,Smith D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Transfusion of D+ red blood cells (RBCs) to D- recipients can be accidental or necessary due to D- RBC shortage. Alloimmunization can complicate future transfusions; implications for women of childbearing age are compounded by possible hemolytic disease of the fetus and newborn. Rh immunoprophylaxis is effec...

journal_title：Journal of clinical apheresis

authors： Werch JB

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Currently, low titer A plasma is used on a routine basis in bleeding trauma patients of unknown AB type. Three AB non-bleeding apheresis patients are presented here who safely received a combination of AB and low titer A plasma during therapeutic plasma exchange (TPE). One control AB patient received AB plas...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Sevcik J,Kiss JE

更新日期：2019-02-01 00:00:00

abstract：:Bone marrow (BM) damage after previous chemotherapy, such as that involving alkylating agents, and radiation therapy alone cannot explain poor hematopoietic progenitor cell mobilization. We examined the T lymphocytes of BM in 67 autologous peripheral blood stem cell transplant (auto-PBSCT) patients with non-Hodgkin ly...

journal_title：Journal of clinical apheresis

authors： Oka S,Nohgawa M

更新日期：2020-07-28 00:00:00

abstract：OBJECTIVE:Effects of therapeutic plasma exchange (TPE) on immune cells and their cytokine production in MS, are unknown. Since interleukine-6 and tumor growth factor-β have critical roles in MS immunopathogenesis, the impacts of TPE on the expression of these cytokines and their receptors on the surface of CD4+ T lymph...

journal_title：Journal of clinical apheresis

authors： Jamshidian A,Abd-Nikfarjam B,Khademi Z,Shaygannejad V,Salehi M

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Patients undergoing therapeutic plasma exchange (TPE) may present with risks for hemorrhage or thrombosis. Use of replacement fluids devoid of coagulation factors will decrease factor levels and platelet levels. There are no established guidelines for hemostasis management in these situations. MATERIALS AND...

journal_title：Journal of clinical apheresis

authors： Zantek ND,Boral LI,Li Y,Yamada C,Svensson AM,Crane JE,Smith RE,Pagano MB,Rollins-Raval MA,Schmidt AE,Wong ECC,Wu Y

更新日期：2018-10-01 00:00:00

abstract：:Folinic acid (FA) has been reported to expand the pool of peripheral blood stem cells (PBSC) after chemotherapy. We evaluated the efficacy of FA for harvesting PBSC following cytotoxic chemotherapy in 4 patients with acute leukemia. After achieving a complete remission (CR), 3 courses of chemotherapy for a consolidati...

journal_title：Journal of clinical apheresis

authors： Teshima T,Harada M,Takamatsu Y,Inaba S,Kondo S,Akashi K,Okamura T,Niho Y

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Specialized centers claim a need for blood component production independent from the general blood transfusion services. We performed a prospective change control analysis of the transfer of platelet (PLT) production for hematological patients at the University Hospital Basel from the Departme...

journal_title：Journal of clinical apheresis

authors： Sigle JP,Medinger M,Stern M,Infanti L,Heim D,Halter J,Gratwohl A,Buser A

更新日期：2012-01-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a condition caused by deficiency of ADAMTS13 resulting in accumulation of ultra large Von Willebrand factor multimers (ULVWF), leading to micro thrombi in multiple organs. The varying susceptibilities of blood group antigens to ADAMTS13 have been demonstrated. A and B antig...

journal_title：Journal of clinical apheresis

authors： Zuberi L,Yerasuri D,Kuriakose P

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Estimation of the total blood volume (TBV) is fundamental to the control of automated red cell exchange (RCE). Error in the TBV estimate can produce outcomes that deviate from the prescribed targets, and may endanger the patient. Both the Spectra Optia and the COBE Spectra use the Nadler formu...

journal_title：Journal of clinical apheresis

authors： Colavita D,Kim HC,Friedman DF

更新日期：2019-12-01 00:00:00

abstract：:Since the introduction of hematopoietic growth factors, the collection of mobilized stem cells via leukapheresis has widely replaced the harvest of bone marrow in both autologous and allogeneic transplantation settings. We investigated the frequency and the extent of anticoagulant-induced electrolyte changes and the c...

journal_title：Journal of clinical apheresis

authors： Schlenke P,Frohn C,Steinhardt MM,Kirchner H,Klüter H

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Hereditary thrombotic thrombocytopenic purpura, also called Upshaw-Schulman syndrome (USS), is a rare disease caused by genetic mutations in the ADAMTS13 gene, which severely decrease the activity of ADAMTS13, a metalloprotease that cleaves von Willebrand factor multimers (VWF). Genotypically identical patie...

journal_title：Journal of clinical apheresis

authors： Kovarova P,Hrdlickova R,Blahutova S,Cermakova Z

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF), also known as nephrogenic sclerosing dermopathy (NSD), is a rare progressive fibrosing disease associated with gadolinium based dyes in patients with renal disease. The exact pathophysiology is not well understood. Accepted treatments include corticosteroids, immune modul...

journal_title：Journal of clinical apheresis

authors： Poisson JL,Low A,Park YA

更新日期：2013-08-01 00:00:00

abstract：:Acute thrombotic thrombocytopenic purpura (TTP) occurred in three patients following abdominal surgeries. One patient underwent extensive lysis for intestinal adhesions with bowel resection, another cholecystectomy for acute cholecystitis, and the third right colectomy and partial intestinal resection for colon cancer...

journal_title：Journal of clinical apheresis

authors： Chang JC,El-Tarabily M,Gupta S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:High-volume plasma exchange (HVPE), defined as an exchange of 8 to 12 L per day per procedure or 15% of the ideal body weight with fresh frozen plasma, has shown promising results in improving the survival of patients with acute liver failure (ALF). However, clinical evidence is limited. The aim of this...

journal_title：Journal of clinical apheresis

authors： Kim JE,Chun S,Sinn DH,Kim NJ,Kim S,Kang W,Kim JM,Choi GS,Joh JW,Cho D

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:There are several regimens used in hematopoietic stem cell (HSC) mobilization in multiple myeloma (MM). Cyclophosphamide (Cy) is one of the most commonly used agents, although it does not always result in collecting adequate number of CD34+ cells. Recently, cytarabine (Ara-C) has been proposed as potentially...

journal_title：Journal of clinical apheresis

authors： Bogucka-Fedorczuk A,Czyz A,Kalicińska E,Sawicki M,Laszkowska-Lewko M,Wicherska-Pawłowska K,Rybka J,Szeremet A,Prajs I,Szymczak D,Wróbel T

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Plasma exchange (PE) and double filtration plasmapheresis (DFPP) are known as effective treatment options for hyperviscosity syndrome (HVS) caused by Waldenstrom macroglobulinemia. Nonetheless, few data are available for the relation between the prescribed dose of apheresis and the reduction rate of target m...

journal_title：Journal of clinical apheresis

authors： Miyamoto Y,Hamasaki Y,Matsumoto A,Doi K,Noiri E,Nangaku M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Perioperative therapeutic plasma exchange in patients with cardiovascular diseases poses several challenges, including alterations in intravascular volume, serum electrolytes, the coagulation cascade, and drug pharmacokinetics. METHODS:This review article summarizes different indications of plasma exchange ...

journal_title：Journal of clinical apheresis

authors： Kanellopoulou T,Kostelidou T

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Factors affecting progenitor cell mobilization in patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) are incompletely understood. The aim of this retrospective study was to determine which factors are crucial for effective mobilization and collection of autologous peripheral blood stem ce...

journal_title：Journal of clinical apheresis

authors： Han X,Ma L,Zhao L,He X,Liu P,Zhou S,Yang J,Qin Y,Yang S,Yao J,Shi Y

更新日期：2012-01-01 00:00:00