Research and development in the blood bank: efforts of a hospital donor center to improve efficiency of in-line leukocyte reduction filters for automated plateletpheresis.

abstract：INTRODUCTION:ABO- or HLA-incompatible kidney transplantation is possible thanks to pretransplant antibody-depletion achieved by extracorporeal-treatment modalities. These methods induce depletion of some plasma proteins and may also impact on proteins involved in hemostasis. METHODS:To determine the impact of one sess...

journal_title：Journal of clinical apheresis

authors： Marlu R,Bennani HN,Seyve L,Malvezzi P,Janbon B,Noble J,Christophe M,Motte L,Imerzoukene F,Chevallier E,Rostaing L,Jouve T

更新日期：2020-08-17 00:00:00

abstract：:A "snapshot" survey of physician coverage for evaluation and supervision of therapeutic apheresis procedures shows significant variation in current clinical practice between 39 blood center-and 41 non-blood center-based programs. Whereas 56% of blood center-based programs usually require physician's "in person" evalua...

journal_title：Journal of clinical apheresis

authors： Woll JE

更新日期：1995-01-01 00:00:00

abstract：:To compare donor demographics and motivations for donation, we surveyed 159 consecutive whole blood donors (WD) and 146 consecutive plateletpheresis donors. All donors had donation experiences of at least 2 gallons (i.e., 16 previous donations). Evaluation of answers to fixed-response and open-ended questions revealed...

journal_title：Journal of clinical apheresis

authors： Julius CJ,Sytsma SR

更新日期：1993-01-01 00:00:00

abstract：:Photopheresis has become a key component in the therapeutic armamentarium of cutaneous T-cell lymphoma, graft-versus-host disease following stem cell transplant, and allograft rejection of solid organs such as heart. Although it is considered a new treatment modality in its present form, the field of phototherapy date...

journal_title：Journal of clinical apheresis

authors： Marques MB,Tuncer HH

更新日期：2006-04-01 00:00:00

abstract：:Until recently, the collection of peripheral blood progenitor cells (PBPC) has been semi-automated by using the COBE Spectra, with the operator manually maintaining the position of the white cells being collected. The COBE Spectra Version 6.0 apheresis device offers the user an automated program for the collection of ...

journal_title：Journal of clinical apheresis

authors： Wilke R,Brettell M,Prince HM,Wolf M,McKenna R,Serpell E,Molloy M,Stevens H,Quinn M,Gates P,Chapple P

更新日期：1999-01-01 00:00:00

abstract：:Blood component donations by apheresis have become more common in modern blood transfusion practices. We compared three apheresis instruments (Fenwal Amicus, Fresenius COM.TEC, and Trima Accel) with regard to platelet (PLT) yield, collection efficiency (CE), and collection rate (CR). The single-needle or double-needle...

journal_title：Journal of clinical apheresis

authors： Keklik M,Eser B,Kaynar L,Sivgin S,Keklik E,Solmaz M,Ozturk A,Buyukoglan R,Yay M,Cetin M,Unal A

更新日期：2015-06-01 00:00:00

abstract：:We present clinical data on two boys with chronic relapsing polyneuropathy. Their recurrent episodes of weakness had produced marked disability which was unresponsive to continuous prednisone therapy. Plasmapheresis produced dramatic improvement in muscle strength and functional ability. The remissions induced have be...

journal_title：Journal of clinical apheresis

authors： Connor RK,Ziter FA,Anstall HB

更新日期：1982-01-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a condition caused by deficiency of ADAMTS13 resulting in accumulation of ultra large Von Willebrand factor multimers (ULVWF), leading to micro thrombi in multiple organs. The varying susceptibilities of blood group antigens to ADAMTS13 have been demonstrated. A and B antig...

journal_title：Journal of clinical apheresis

authors： Zuberi L,Yerasuri D,Kuriakose P

更新日期：2009-01-01 00:00:00

abstract：:This study chronicles leukocyte- and erythrocyte-depleted platelet concentrate collection by a dual stage channel in which three variables: 1) donor peripheral blood platelet concentration, 2) total blood processed, and 3) collection volume were statistically correlated with platelet yield as determined by a multiple ...

journal_title：Journal of clinical apheresis

authors： Hester JP,Kellogg RM,Mulzet AP,Freireich EJ

更新日期：1985-01-01 00:00:00

abstract：:Modern techniques of mechanical hemapheresis have made it possible to selectively remove vast quantities of lymphocytes and plasma immunoglobulins, and the concentration of these substances in donor blood can fall below the normal range. It is feared that this may lead to immunosuppression; a condition associated in s...

journal_title：Journal of clinical apheresis

authors： Strauss RG

更新日期：1984-01-01 00:00:00

abstract：:Peripheral blood stem cells (PBSC) reinfusion appears to hasten hematologic reconstitution following myeloablative therapy. While procurement of PBSC adds apheresis procedures, rapid engraftment could decrease the demand for platelet transfusions. To determine the impact of PBSC collection on workload in our apheresis...

journal_title：Journal of clinical apheresis

authors： Ghalie R,McLeod B,Richman C,Valentino L,Manson S,Netols C,Kaizer H

更新日期：1992-01-01 00:00:00

abstract：:This study was undertaken to evaluate the relationship between the time to recovery of peripheral blood counts and CD34+ cells in the peripheral blood (PB) and apheresis collections of patients undergoing intensive chemotherapy followed by rhG-CSF. Twenty-three patients with a median age of 42 years (range 17-64) with...

journal_title：Journal of clinical apheresis

authors： Williams O,Demirer T,Lilleby K,Buckner CD,Bensinger WI

更新日期：1998-01-01 00:00:00

abstract：:In the United States, therapeutic plasma exchange (TPE) is both performed and requested by a wide range of services, often on an empiric basis (before a diagnosis is established). Whether empiric therapy is beneficial has not been established. Patients were identified from an electronic procedure log that included tho...

journal_title：Journal of clinical apheresis

authors： Yeo FE,Bohen EM,Yuan CM,Sawyers ES,Abbott KC

更新日期：2005-12-01 00:00:00

abstract：:We have reviewed our initial experience with a program of concurrent collection of plasma (CCP) during plateletpheresis, which was instituted to increase the number of units of fresh frozen plasma produced by our hospital-based donor service. Sixty percent of eligible donors (1,006 of 1,682) participated in CCP, and 2...

journal_title：Journal of clinical apheresis

authors： Burger SR,Thomas BT,Grishaber JE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Autologous stem cell transplantation (auto-SCT) is a treatment approach in non-Hodgkin lymphoma (NHL) patients. The options for mobilization of CD34+ cells to support high-dose therapy are granulocyte-colony stimulating factors (G-CSFs) alone or after chemotherapy. Limited data exist on the efficacy of lipeg...

journal_title：Journal of clinical apheresis

authors： Partanen A,Turunen A,Valtola J,Vasala K,Ågren L,Penttilä K,Pyörälä M,Kuittinen T,Mäntymaa P,Pelkonen J,Jantunen E,Varmavuo V

更新日期：2020-08-01 00:00:00

abstract：:Acute thrombotic thrombocytopenic purpura (TTP) occurred in three patients following abdominal surgeries. One patient underwent extensive lysis for intestinal adhesions with bowel resection, another cholecystectomy for acute cholecystitis, and the third right colectomy and partial intestinal resection for colon cancer...

journal_title：Journal of clinical apheresis

authors： Chang JC,El-Tarabily M,Gupta S

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study was to analyze the impact of various donor and machine parameters on PLT yield in 127 PLT apheresis procedures, to optimize PLT yield achieving clinical and economic advantages. One hundred and twenty-seven apheresis procedures were analyzed. Age, gender, volume processed, Hb, and PLT precounts w...

journal_title：Journal of clinical apheresis

authors： Enein AA,Hussein EA,El Shafie S,Hallouda M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Transfusion of D+ red blood cells (RBCs) to D- recipients can be accidental or necessary due to D- RBC shortage. Alloimmunization can complicate future transfusions; implications for women of childbearing age are compounded by possible hemolytic disease of the fetus and newborn. Rh immunoprophylaxis is effec...

journal_title：Journal of clinical apheresis

authors： Werch JB

更新日期：2010-01-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a recognized complication of malignant hypertension (HTN). Such patients have blood pressures > or = 200/140 mmHg but the condition is defined by the presence of papilledema and is frequently complicated by acute renal failure. Here we report two patients with severe HTN (systolic >...

journal_title：Journal of clinical apheresis

authors： Egan JA,Bandarenko N,Hay SN,Paradowski L,Goldberg R,Nickeleit V,Brecher ME

更新日期：2004-01-01 00:00:00

abstract：:Targeted extracorporeal granulocyte and monocyte apheresis (GMA) has produced clinical efficacy together with down modulation of specific inflammatory cytokines in patients with ulcerative colitis (UC). This study was to investigate if preoperative GMA produces immunological effect on dysregulated immune activity afte...

journal_title：Journal of clinical apheresis

authors： Bamba T,Yamamoto T,Umegae S,Matsumoto K

更新日期：2014-04-01 00:00:00

abstract：:The recent introduction of low-density lipoprotein (LDL)/very low-density lipoprotein (VLDL) selective-removal systems offers an alternative to plasma exchange (PE). For the last 10 years, we have treated a male homozygous hypercholesterolemia type IIA patient with PE using 5% normal serum albumin (NSA) replacement, P...

journal_title：Journal of clinical apheresis

authors： Burgstaler EA,Pineda AA

更新日期：1992-01-01 00:00:00

abstract：:The cell separator MCS-3P is an apheresis system offering the flexibility to collect standardized red blood cells, plasma, and/or platelets from one donor. Two different programs were used for the red cell apheresis--RBCP (collection of one unit of red cells and two units of plasma) and RBCPS (one unit of red cells an...

journal_title：Journal of clinical apheresis

authors： Matthes G,Tofote U,Krause KP,Pawlow I,Kucera W,Lerche D

更新日期：1994-01-01 00:00:00

abstract：:The influence of 6 weeks of cyclosporin A (CYA), followed by a further 6 weeks of this agent in combination with plasma exchange (PE), was defined on panel reactivity and titre of preformed cytotoxic antibodies in stable patients on haemodialysis awaiting renal transplantation. Nine individuals with antibodies to 30% ...

journal_title：Journal of clinical apheresis

authors： Swanepoel CR,Cassidy MJ,May M,Oudshoorn M,du Toit E,Wood L,Jacobs P

更新日期：1991-01-01 00:00:00

abstract：:Antisynthetase syndrome (ASS) is a rare condition characterized by interstitial lung disease (ILD), inflammatory myositis, fever, Raynaud phenomenon, mechanic's hand, and inflammatory polyarthritis in the setting of antibodies to amino acyl-transfer RNA synthetases, with anti-Jo-1 antibody being the most common. Progn...

journal_title：Journal of clinical apheresis

authors： Omotoso BA,Ogden MI,Balogun RA

更新日期：2015-12-01 00:00:00

abstract：:"Leukocyte-depleted" platelet concentrates (LD-SDPC) were prepared by cotton-wool and by polyester filtration of "leukocyte-poor" PC collected by the elutriation technique. The storage characteristics of LD-SDPC were comparable to those of the filtered pools of multiple donor platelet concentrates (LD-MDPC). However, ...

journal_title：Journal of clinical apheresis

authors： Elias MK,de Wolf JT,Blom N,Rijskamp L,Halie RM,Smit Sibinga CT

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:In organ transplantation, apheresis is frequently used for removal of anti-HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi-selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to reach post-treatment objectives is also unknown. ...

journal_title：Journal of clinical apheresis

authors： Jambon F,Merville P,Guidicelli G,Taton B,De Précigout V,Couzi L,Moreau K,Visentin J

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

更新日期：2016-12-01 00:00:00

abstract：:During the course of heparin-induced extracorporeal lipoprotein apheresis, a patient with no prior known renal impairment or proteinuria demonstrated sustained improvement in estimated glomerular filtration rate, commensurate with reduction in serum lipids and creatine phosphokinase levels. Causes and implications of ...

journal_title：Journal of clinical apheresis

authors： Chandran PK

更新日期：2011-01-01 00:00:00

abstract：:One of the most serious problems in applying leukapheresis to human infants is the large extracorporeal blood volume (ECV), resulting in substantial loss of platelets and red blood cells (RBCs). In this study, we developed a safe and effective modified procedure to collect peripheral blood stem cells (PBSCs) from rhes...

journal_title：Journal of clinical apheresis

authors： Ageyama N,Kimikawa M,Eguchi K,Ono F,Shibata H,Yoshikawa Y,Terao K

更新日期：2003-01-01 00:00:00

abstract：:Plerixafor in combination with granulocyte-colony stimulating factor (G-CSF) is approved for autologous stem cell mobilization in poor mobilizing patients with multiple myeloma or malignant lymphoma. The purpose of this study was to evaluate efficacy and safety of plerixafor in an immediate rescue approach, administra...

journal_title：Journal of clinical apheresis

authors： Worel N,Fritsch G,Agis H,Böhm A,Engelich G,Leitner GC,Geissler K,Gleixner K,Kalhs P,Buxhofer-Ausch V,Keil F,Kopetzky G,Mayr V,Rabitsch W,Reisner R,Rosskopf K,Ruckser R,Zoghlami C,Zojer N,Greinix HT

更新日期：2017-08-01 00:00:00