Literature review of apheresis procedures performed perioperatively in cardiac surgery for ASFA category indications.


BACKGROUND:Perioperative therapeutic plasma exchange in patients with cardiovascular diseases poses several challenges, including alterations in intravascular volume, serum electrolytes, the coagulation cascade, and drug pharmacokinetics. METHODS:This review article summarizes different indications of plasma exchange for patients requiring cardiac surgery based on reported case reports and case series. RESULTS:The most common reported indication is plasma exchange for the management of allosensitized cardiac transplant candidate patients in combination with immunosuppressive regimens, which increases the likelihood of obtaining a cross-match-negative allograft, improving post-transplant clinical outcome. The second most common indication is for patients with a history of heparin-induced thrombocytopenia syndrome that permits the use of heparin in cardiopulmonary bypass in an urgent cardiac surgery. Less common indications are restoration of clotting factors for patients with congenital bleeding disorders or removal of cold agglutinins. No severe complications were described in reported cases. CONCLUSION:Therapeutic plasma exchange is an effective and safe procedure that could be performed preoperatively and intraoperatively in urgent cardiac surgery for the management of antibody-mediated disorders including allosensitized cardiac transplant candidate patients or patients with heparin-induced thrombocytopenia syndrome.


J Clin Apher


Kanellopoulou T,Kostelidou T




Has Abstract


2019-08-01 00:00:00












  • Effects of LDL-immunoapheresis on plasma concentrations of vitamin E and carotenoids in patients with familial hypercholesterolemia.

    abstract::Recently very potent extracorporeal cholesterol-lowering treatment options have become available for patients with hypercholesterolemia. LDL immunoapheresis treatment selectively removes LDL and lipoprotein(a) from the circulation. Since LDL is the major carrier of lipophilic antioxidants in plasma, the purpose of the...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Cauza E,Jansen M,Resch U,Dunky A,Derfler K,Winklhofer-Roob BM,Kostner K

    更新日期:2004-01-01 00:00:00

  • Therapeutic plasma exchange may adjust IL-6 and TGF-β signals in relapsed MS patients peripheral blood.

    abstract:OBJECTIVE:Effects of therapeutic plasma exchange (TPE) on immune cells and their cytokine production in MS, are unknown. Since interleukine-6 and tumor growth factor-β have critical roles in MS immunopathogenesis, the impacts of TPE on the expression of these cytokines and their receptors on the surface of CD4+ T lymph...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Jamshidian A,Abd-Nikfarjam B,Khademi Z,Shaygannejad V,Salehi M

    更新日期:2020-04-01 00:00:00

  • Management of systemic unfractionated heparin anticoagulation during therapeutic plasma exchange.

    abstract:BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

    更新日期:2016-12-01 00:00:00

  • Postdonation platelet counts are safe when collecting platelets with the Trima Accel using a postdonation platelet count target of > or =50,000 platelets/microL.

    abstract::In December 2007, the FDA issued a guidance document recommending that apheresis cell separators be configured with a postdonation platelet count target of > or =100,000 platelets/microL. Currently, our Trima Accel apheresis cell separators are configured with a postdonation platelet count target of > or =50,000 plate...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Alex J,Roberts B,Raife T

    更新日期:2009-01-01 00:00:00

  • Heparin-induced thrombocytopenia associated with collection of hematopoietic progenitor cells by apheresis.

    abstract::Heparin-induced thrombocytopenia (HIT) can occur following exposure to heparin and is characterized by thrombocytopenia with increased risk for thrombosis. This condition is mediated by formation of immunoglobulin G antibodies against platelet factor 4/heparin complexes that can subsequently lead to platelet activatio...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Raval JS,Park YA,Perjar I,Mazepa MA,Vincent BG,Ma AD,Rollins-Raval MA

    更新日期:2020-01-01 00:00:00

  • Report of the ASFA apheresis registry study on Wilson's disease.

    abstract:PURPOSE:Wilson's disease is a rare autosomal recessive genetic disorder that results in accumulation of copper in the liver, brain, cornea and kidney. Therapeutic plasma exchange (TPE) has been used to remove copper and provide a bridge to liver transplantation. We report here the collective experiences through the ASF...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,多中心研究


    authors: Pham HP,Schwartz J,Cooling L,Hofmann JC,Kim HC,Morgan S,Pagano MB,Schneiderman J,Winters JL,Yamada C,Wong EC,Wu Y

    更新日期:2016-02-01 00:00:00

  • Effects of preoperative leukocytapheresis on inflammatory cytokines following surgery for ulcerative colitis: a prospective randomized study.

    abstract::Targeted extracorporeal granulocyte and monocyte apheresis (GMA) has produced clinical efficacy together with down modulation of specific inflammatory cytokines in patients with ulcerative colitis (UC). This study was to investigate if preoperative GMA produces immunological effect on dysregulated immune activity afte...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,随机对照试验


    authors: Bamba T,Yamamoto T,Umegae S,Matsumoto K

    更新日期:2014-04-01 00:00:00

  • Assessment of software-derived predictive algorithms for platelet yield and blood cell count after apheresis.

    abstract:INTRODUCTION:Algorithms have been developed to predict the platelet yield after apheresis from the donor's data, as well as the effect on the blood cell count, to extract an acceptable platelet number without affecting the donor. However, the evaluation of these algorithms has not been widely reported. This study aimed...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Cienfuegos-Pecina E,Ayala-De la Cruz S,Leal-Nava ER,Pérez-Olvera JA,Llaca-Díaz JM,Avilés-Rodríguez LE,Pérez-Chávez F,Díaz-Chuc EA

    更新日期:2020-10-05 00:00:00

  • Autoimmunity in transfusion babesiosis: a spectrum of clinical presentations.

    abstract::Transfusion-acquired babesiosis can be an asymptomatic or self-limited febrile hemolytic illness in a healthy host. A persistent, relapsing, and/or fulminant course with the development of life-threatening complications may be seen in immunocompromised or splenectomized patients. As in malaria, erythrocyte parasitemia...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Herman JH,Ayache S,Olkowska D

    更新日期:2010-01-01 00:00:00

  • Blood bank issues associated with red cell exchanges in sickle cell disease.

    abstract::Sickle cell disease (SCD) patients are prone to develop complications that include stroke, acute chest syndrome, and other crises. Some of these complications require chronic transfusion therapy or red cell exchange (RCE), either for therapeutic or prophylactic reasons. Due to a discrepancy of red cell antigens betwee...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审


    authors: Sarode R,Altuntas F

    更新日期:2006-12-01 00:00:00

  • Efficacy of plasmapheresis and semi-selective immunoadsorption for removal of anti-HLA antibodies.

    abstract:BACKGROUND:In organ transplantation, apheresis is frequently used for removal of anti-HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi-selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to reach post-treatment objectives is also unknown. ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Jambon F,Merville P,Guidicelli G,Taton B,De Précigout V,Couzi L,Moreau K,Visentin J

    更新日期:2020-11-30 00:00:00

  • Convalescent plasma therapy in patients with COVID-19.

    abstract::There are currently no licensed vaccines or therapeutics for COVID-19. Anti-SARS CoV-2 antibody-containing plasmas, obtained from the recovered individuals who had confirmed COVID-19, have been started to be collected using apheresis devices and stored in blood banks in some countries in order to administer to the pat...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审


    authors: Yiğenoğlu TN,Hacıbekiroğlu T,Berber İ,Dal MS,Baştürk A,Namdaroğlu S,Korkmaz S,Ulas T,Dal T,Erkurt MA,Turgut B,Altuntaş F

    更新日期:2020-08-01 00:00:00

  • ECP as additional immunomodulation in idiopathic hyperammonemia and recurrent hypercapnic respiratory failure early post lung transplantation.

    abstract::Extra-corporeal photopheresis (ECP) is known as safe ultimate treatment option for chronic lung allograft dysfunction (CLAD). Here, we report the first case of ECP as "second-line" immunomodulatory therapy early post-transplant in an adult patient undergoing lung transplantation for severe chronic thromboembolic pulmo...

    journal_title:Journal of clinical apheresis



    authors: Steinack C,Robinson CA,Nägeli M,Inci I,Benden C

    更新日期:2020-08-24 00:00:00

  • Refractory thyrotoxicosis induced by iodinated contrast agents treated with therapeutic plasma exchange. A case report.

    abstract::Excess free iodide in the blood (ingested or injected) may cause thyrotoxicosis in patients at risk. Iodinated contrast solutions contain small amounts of free iodide and may be of significance for patients affected by Graves' disease, multinodular goiter or living in areas of iodine deficiency. Herein, we report a 57...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Pasimeni G,Caroli F,Spriano G,Antonini M,Baldelli R,Appetecchia M

    更新日期:2008-01-01 00:00:00

  • Antibody response to pneumococcal polysaccharide vaccine in myasthenia gravis: effect of therapeutic plasmapheresis.

    abstract::The removal of specific antibody in experimental animals has been reported to result in a subsequent increase in antibody to levels equal to (rebound) or exceeding those existing prior to removal (overshoot). Anecdotal reports suggest that rebound antibody synthesis after plasmapheresis may occur in humans with autoim...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Nasca TJ,Muder RR,Thomas DB,Schrecker JC,Ruben FL

    更新日期:1990-01-01 00:00:00

  • Research and development in the blood bank: efforts of a hospital donor center to improve efficiency of in-line leukocyte reduction filters for automated plateletpheresis.

    abstract::In-line leukocyte reduction filters (LRF) are available for use with an automated plateletpheresis (PPH) system. Initially, 62% of PPH units produced with such a filter (LRF6, N = 29) had postfiltration (POF) white blood cell (WBC) counts < 5 x 10(6), with a mean POF WBC of 42 x 10(6). In an attempt to decrease POF WB...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Drew MJ,Hodges J

    更新日期:1995-01-01 00:00:00

  • Initial experience with high-volume plasma exchange in patients with acute liver failure.

    abstract:BACKGROUND/AIMS:High-volume plasma exchange (HVPE), defined as an exchange of 8 to 12 L per day per procedure or 15% of the ideal body weight with fresh frozen plasma, has shown promising results in improving the survival of patients with acute liver failure (ALF). However, clinical evidence is limited. The aim of this...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Kim JE,Chun S,Sinn DH,Kim NJ,Kim S,Kang W,Kim JM,Choi GS,Joh JW,Cho D

    更新日期:2021-01-05 00:00:00

  • Continuous-flow techniques for platelet concentrate collection: a step toward standardization and yield predictability.

    abstract::This study chronicles leukocyte- and erythrocyte-depleted platelet concentrate collection by a dual stage channel in which three variables: 1) donor peripheral blood platelet concentration, 2) total blood processed, and 3) collection volume were statistically correlated with platelet yield as determined by a multiple ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Hester JP,Kellogg RM,Mulzet AP,Freireich EJ

    更新日期:1985-01-01 00:00:00

  • The impact of citrate concentration on adhesion of platelets and leukocytes to adsorbents in whole blood lipoprotein apheresis.

    abstract::Lipoprotein apheresis is applied to deplete low density lipoprotein and other apolipoprotein B containing lipoproteins in patients with severe familial hypercholesterolemia, hypertriglyceridemia associated pancreatitis, or lipoprotein (a)-hyperlipoproteinemia. Anticoagulation of the extracorporeal circuit may influenc...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Weiss R,Fischer MB,Weber V

    更新日期:2017-12-01 00:00:00

  • Comparison of plateletpheresis on the Fresenius AS.TEC 204 and Haemonetics MCS 3p.

    abstract::This is an attempt at comparing two cell separators for plateletpheresis, namely the Fresenius AS.TEC 204 and Haemonetics MCS 3p, at a tertiary care center in India. Donors who weighed between 55-75 kg, who had a hematocrit of 41-43%, and platelet counts of 250x10(3)-400x10(3)/microl were selected for the study. The c...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Ranganathan S

    更新日期:2007-02-01 00:00:00

  • Effect of heparin-induced extracorporeal lipoprotein apheresis on renal function.

    abstract::During the course of heparin-induced extracorporeal lipoprotein apheresis, a patient with no prior known renal impairment or proteinuria demonstrated sustained improvement in estimated glomerular filtration rate, commensurate with reduction in serum lipids and creatine phosphokinase levels. Causes and implications of ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Chandran PK

    更新日期:2011-01-01 00:00:00

  • Early response to caplacizumab and rituximab after anaphylaxis to Octaplas plasma in a patient with thrombotic thrombocytopenic purpura.

    abstract::Management of aTTP in patients who refuse or are intolerant to plasma remains challenging, but new drugs can be implemented with success. A 39-year-old woman presented to the Emergency department for bruises at the upper and lower limbs together with worsening anemia and thrombocytopenia; PLASMIC score was seven, indi...

    journal_title:Journal of clinical apheresis



    authors: Perrone S,Passucci M,Ortu La Barbera E,Capriata M,Ferretti A,Mecozzi A,Giovangrossi P,Equitani F,Cimino G

    更新日期:2021-01-18 00:00:00

  • Modification of the leukapheresis procedure for use in rhesus monkeys (Macaca mulata).

    abstract::One of the most serious problems in applying leukapheresis to human infants is the large extracorporeal blood volume (ECV), resulting in substantial loss of platelets and red blood cells (RBCs). In this study, we developed a safe and effective modified procedure to collect peripheral blood stem cells (PBSCs) from rhes...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Ageyama N,Kimikawa M,Eguchi K,Ono F,Shibata H,Yoshikawa Y,Terao K

    更新日期:2003-01-01 00:00:00

  • Plasma exchange for heparin-induced thrombocytopenia in patients on extracorporeal circuits: A challenging case and a survey of the field.

    abstract::Current management of heparin-induced thrombocytopenia (HIT) involves prompt discontinuation of all heparin products and concomitant initiation of a direct thrombin or anti-Xa inhibitor for anticoagulation. In the setting of HIT complicated by an urgent need for cardiopulmonary bypass (CPB), the safety and the efficac...

    journal_title:Journal of clinical apheresis



    authors: Cho JH,Parilla M,Treml A,Wool GD

    更新日期:2019-02-01 00:00:00

  • Computerization of plateletpheresis quality control records with a commercially available spreadsheet program.

    abstract::Many apheresis units lack the resources to acquire customized computer software for record keeping. We have adapted a commercially available "spreadsheet" program (Lotus 1-2-3) to aid in quality control activities for plateletpheresis. Data are entered in a grid pattern wherein each donation occupies one row and succe...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: McLeod BC,Viernes A,Reed S,Sassetti RJ

    更新日期:1990-01-01 00:00:00

  • Tempo of hematologic recovery correlates with peripheral blood CD34+ cell level in patients undergoing stem cell mobilization.

    abstract::This study was undertaken to evaluate the relationship between the time to recovery of peripheral blood counts and CD34+ cells in the peripheral blood (PB) and apheresis collections of patients undergoing intensive chemotherapy followed by rhG-CSF. Twenty-three patients with a median age of 42 years (range 17-64) with...

    journal_title:Journal of clinical apheresis

    pub_type: 临床试验,杂志文章


    authors: Williams O,Demirer T,Lilleby K,Buckner CD,Bensinger WI

    更新日期:1998-01-01 00:00:00

  • Effects of extracorporeal hemapheresis therapy on blood rheology.

    abstract::The blood flow property is one of the factors determining blood perfusion and oxygen supply. The viscosity of the blood is primarily related to the hematocrit, but also to the amount of fibrinogen and other macromolecules present in the blood. Patients with ischemic heart disease have shown a rapid and safe improvemen...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Fadul JE,Linde T,Sandhagen B,Wikström B,Danielson BG

    更新日期:1997-01-01 00:00:00

  • Surviving peer review.

    abstract::The process of publishing original work in a peer review journal is not complete at the point where the manuscript is first submitted. The journal editors will submit the manuscript to peer review whereby outside experts are asked to vet the manuscript for scientific merit, originality and quality. Reviewers' comments...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审


    authors: Weinstein R

    更新日期:2020-08-07 00:00:00

  • Formatting an experiential learning education module to encourage dysphagia assessment in apheresis patients.

    abstract:BACKGROUND:Dysphagia screening is oftentimes a focus of hospitalized patients, but dysphagia can also occur in outpatient settings. Dysphagia can be overlooked by nurses and clinicians, and it is therefore important to educate nurses on the importance of dysphagia screenings. METHODS:This was a randomized prospective ...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,随机对照试验


    authors: West J,Stutzman SE,Atem F,Olson DM

    更新日期:2018-02-01 00:00:00

  • Lipid-apheresis improves microcirculation of the upper limbs.

    abstract::Lipid-apheresis (LA) is thought to improve microcirculation. However, limited data are available on the effects on peripheral microcirculation. We investigated upper limb microcirculation of 22 patients undergoing regular LA on a weekly basis before and after LA. Using standardized semiquantitative scales, we analyzed...

    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章


    authors: Rossenbach J,Mueller GA,Lange K,Armstrong VW,Schmitto JD,Hintze E,Helfmann J,Konstantinides S,Koziolek MJ

    更新日期:2011-01-01 00:00:00