Acquired immunodeficiency syndrome (AIDS)--apheresis and operative risks.

Abstract:

:The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related conditions with presumed autoimmune basis. Perfusion of plasma over immobilized protein A columns is being evaluated as a possible immunomodulatory and antitumor therapy in patients with AIDS related Kaposi's sarcoma. Although apheresis procedures as a therapeutic modality in AIDS related conditions are still at the experimental stage, preliminary results are encouraging. The possible transmission of the disease by blood products presents a health hazard to health workers involved in the field of apheresis. Since the mode of transmission of the disease appears to be similar to hepatitis B, strict hepatitis B precautions should be enforced in every case in which AIDS suspected blood is being processed.

journal_name

J Clin Apher

authors

Kiprov DD,Lippert R,Sandstrom E,Jones FR,Cohen RJ,Abrams D,Busch DF

doi

10.1002/jca.2920020436

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

427-40

issue

4

eissn

0733-2459

issn

1098-1101

journal_volume

2

pub_type

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