Assessment of software-derived predictive algorithms for platelet yield and blood cell count after apheresis.

abstract：:Since the introduction of hematopoietic growth factors, the collection of mobilized stem cells via leukapheresis has widely replaced the harvest of bone marrow in both autologous and allogeneic transplantation settings. We investigated the frequency and the extent of anticoagulant-induced electrolyte changes and the c...

journal_title：Journal of clinical apheresis

authors： Schlenke P,Frohn C,Steinhardt MM,Kirchner H,Klüter H

更新日期：2000-01-01 00:00:00

abstract：:Lipid-apheresis (LA) is thought to improve microcirculation. However, limited data are available on the effects on peripheral microcirculation. We investigated upper limb microcirculation of 22 patients undergoing regular LA on a weekly basis before and after LA. Using standardized semiquantitative scales, we analyzed...

journal_title：Journal of clinical apheresis

authors： Rossenbach J,Mueller GA,Lange K,Armstrong VW,Schmitto JD,Hintze E,Helfmann J,Konstantinides S,Koziolek MJ

更新日期：2011-01-01 00:00:00

abstract：:One of the most serious problems in applying leukapheresis to human infants is the large extracorporeal blood volume (ECV), resulting in substantial loss of platelets and red blood cells (RBCs). In this study, we developed a safe and effective modified procedure to collect peripheral blood stem cells (PBSCs) from rhes...

journal_title：Journal of clinical apheresis

authors： Ageyama N,Kimikawa M,Eguchi K,Ono F,Shibata H,Yoshikawa Y,Terao K

更新日期：2003-01-01 00:00:00

abstract：:The purpose of this study is to determine whether immunoadsorption treatment using a dextran sulfate (DS) column can remove high-avidity anti-double-stranded DNA (anti-dsDNA) antibody from the blood of patients with systemic lupus erythematosus (SLE). Before and after each immunoadsorption therapy routine, titers of t...

journal_title：Journal of clinical apheresis

authors： Matsuki Y,Suzuki K,Kawakami M,Ishizuka T,Kawaguchi Y,Hidaka T,Nakamura H

更新日期：1996-01-01 00:00:00

abstract：:Management of aTTP in patients who refuse or are intolerant to plasma remains challenging, but new drugs can be implemented with success. A 39-year-old woman presented to the Emergency department for bruises at the upper and lower limbs together with worsening anemia and thrombocytopenia; PLASMIC score was seven, indi...

journal_title：Journal of clinical apheresis

authors： Perrone S,Passucci M,Ortu La Barbera E,Capriata M,Ferretti A,Mecozzi A,Giovangrossi P,Equitani F,Cimino G

更新日期：2021-01-18 00:00:00

abstract：:Therapeutic plasma exchange (TPE) is an increasingly utilized immunosuppressive adjunct for treatment of antibody-mediated rejection (AMR) following organ transplantation. TPE works through removal of donor-specific HLA antibodies (DSAs) in the recipient's plasma. However, there is no clear laboratory measure evaluati...

journal_title：Journal of clinical apheresis

authors： Jackups R Jr,Canter C,Sweet SC,Mohanakumar T,Morris GP

更新日期：2013-08-01 00:00:00

abstract：:Prestorage leukocyte reduction of platelet concentrates may reduce adverse effects of transfusion while affording better quality control. Platelets and leukocytes may undergo activation during storage, which could affect the performance of leukocyte reduction filters. The purpose of this study was to evaluate the effi...

journal_title：Journal of clinical apheresis

authors： Jin YS,Mintz PD

更新日期：1997-01-01 00:00:00

abstract：:The blood flow property is one of the factors determining blood perfusion and oxygen supply. The viscosity of the blood is primarily related to the hematocrit, but also to the amount of fibrinogen and other macromolecules present in the blood. Patients with ischemic heart disease have shown a rapid and safe improvemen...

journal_title：Journal of clinical apheresis

authors： Fadul JE,Linde T,Sandhagen B,Wikström B,Danielson BG

更新日期：1997-01-01 00:00:00

abstract：:Thrombopoietin (TPO) serum levels in 14 patients (9 male and 5 female, mean age 36 years, range 16 to 55 years) with breast cancer (n = 5), testicular cancer (n = 7), or lymphoma (n = 2), undergoing high dose chemotherapy with peripheral blood stem cell (PBSC) transplantation, were evaluated at the first day of the mo...

journal_title：Journal of clinical apheresis

authors： Bojko P,Nowak N,Moritz T,Flasshove M,Harstrick A,Seeber S

更新日期：1999-01-01 00:00:00

abstract：:Thrombopoietin (c-Mpl ligand) is the hematopoietic growth factor that is responsible for regulating the production of platelets from bone marrow megakaryocytes. This approximately 90 kd protein has recently been isolated and is comprised of an erythropoietin domain that is approximately 50% homologous to erythropoieti...

journal_title：Journal of clinical apheresis

authors： Kuter DJ

更新日期：1996-01-01 00:00:00

abstract：:During the course of heparin-induced extracorporeal lipoprotein apheresis, a patient with no prior known renal impairment or proteinuria demonstrated sustained improvement in estimated glomerular filtration rate, commensurate with reduction in serum lipids and creatine phosphokinase levels. Causes and implications of ...

journal_title：Journal of clinical apheresis

authors： Chandran PK

更新日期：2011-01-01 00:00:00

abstract：:Blood component donations by apheresis have become more common in modern blood transfusion practices. We compared three apheresis instruments (Fenwal Amicus, Fresenius COM.TEC, and Trima Accel) with regard to platelet (PLT) yield, collection efficiency (CE), and collection rate (CR). The single-needle or double-needle...

journal_title：Journal of clinical apheresis

authors： Keklik M,Eser B,Kaynar L,Sivgin S,Keklik E,Solmaz M,Ozturk A,Buyukoglan R,Yay M,Cetin M,Unal A

更新日期：2015-06-01 00:00:00

abstract：:Recently very potent extracorporeal cholesterol-lowering treatment options have become available for patients with hypercholesterolemia. LDL immunoapheresis treatment selectively removes LDL and lipoprotein(a) from the circulation. Since LDL is the major carrier of lipophilic antioxidants in plasma, the purpose of the...

journal_title：Journal of clinical apheresis

authors： Cauza E,Jansen M,Resch U,Dunky A,Derfler K,Winklhofer-Roob BM,Kostner K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Hereditary thrombotic thrombocytopenic purpura, also called Upshaw-Schulman syndrome (USS), is a rare disease caused by genetic mutations in the ADAMTS13 gene, which severely decrease the activity of ADAMTS13, a metalloprotease that cleaves von Willebrand factor multimers (VWF). Genotypically identical patie...

journal_title：Journal of clinical apheresis

authors： Kovarova P,Hrdlickova R,Blahutova S,Cermakova Z

更新日期：2019-02-01 00:00:00

abstract：:Many practitioners believe in the phenomenon of being labeled either a "black cloud" or "white cloud" while on-call. A "white-cloud" physician is usually defined as one who sees fewer cases while a "black-cloud" is one who often receives more cases. To evaluate these phenomena, a 35-month prospective study was designe...

journal_title：Journal of clinical apheresis

authors： Staley EM,Raju D,Williams LA 3rd,Kim CH,Jiang N,Pham HP

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:ABO- or HLA-incompatible kidney transplantation is possible thanks to pretransplant antibody-depletion achieved by extracorporeal-treatment modalities. These methods induce depletion of some plasma proteins and may also impact on proteins involved in hemostasis. METHODS:To determine the impact of one sess...

journal_title：Journal of clinical apheresis

authors： Marlu R,Bennani HN,Seyve L,Malvezzi P,Janbon B,Noble J,Christophe M,Motte L,Imerzoukene F,Chevallier E,Rostaing L,Jouve T

更新日期：2020-08-17 00:00:00

abstract：:The literature on the use of therapeutic apheresis is often criticized for the preponderance of low to very low quality evidence. Shehata et al. examined the apheresis literature published between 1976 and 1999 and found a lack of randomized controlled trials with those identified demonstrating significant limitations...

journal_title：Journal of clinical apheresis

authors： Winters JL

更新日期：2013-02-01 00:00:00

abstract：:The influence of 6 weeks of cyclosporin A (CYA), followed by a further 6 weeks of this agent in combination with plasma exchange (PE), was defined on panel reactivity and titre of preformed cytotoxic antibodies in stable patients on haemodialysis awaiting renal transplantation. Nine individuals with antibodies to 30% ...

journal_title：Journal of clinical apheresis

authors： Swanepoel CR,Cassidy MJ,May M,Oudshoorn M,du Toit E,Wood L,Jacobs P

更新日期：1991-01-01 00:00:00

abstract：:We have reviewed our initial experience with a program of concurrent collection of plasma (CCP) during plateletpheresis, which was instituted to increase the number of units of fresh frozen plasma produced by our hospital-based donor service. Sixty percent of eligible donors (1,006 of 1,682) participated in CCP, and 2...

journal_title：Journal of clinical apheresis

authors： Burger SR,Thomas BT,Grishaber JE

更新日期：1994-01-01 00:00:00

abstract：:The cell separator MCS-3P is an apheresis system offering the flexibility to collect standardized red blood cells, plasma, and/or platelets from one donor. Two different programs were used for the red cell apheresis--RBCP (collection of one unit of red cells and two units of plasma) and RBCPS (one unit of red cells an...

journal_title：Journal of clinical apheresis

authors： Matthes G,Tofote U,Krause KP,Pawlow I,Kucera W,Lerche D

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Factors affecting progenitor cell mobilization in patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) are incompletely understood. The aim of this retrospective study was to determine which factors are crucial for effective mobilization and collection of autologous peripheral blood stem ce...

journal_title：Journal of clinical apheresis

authors： Han X,Ma L,Zhao L,He X,Liu P,Zhou S,Yang J,Qin Y,Yang S,Yao J,Shi Y

更新日期：2012-01-01 00:00:00

abstract：:Bone marrow (BM) damage after previous chemotherapy, such as that involving alkylating agents, and radiation therapy alone cannot explain poor hematopoietic progenitor cell mobilization. We examined the T lymphocytes of BM in 67 autologous peripheral blood stem cell transplant (auto-PBSCT) patients with non-Hodgkin ly...

journal_title：Journal of clinical apheresis

authors： Oka S,Nohgawa M

更新日期：2020-07-28 00:00:00

abstract：:Mobilization regimens for CD34+ cells have generally been judged successful based on the number of cells collected without evaluating mobilization separately from collection. Using retrospective data for patients who collected CD34+ cells on Total Therapy protocols 3a/3b (VTD-PACE) and Total Therapy 4/5 using a novel ...

journal_title：Journal of clinical apheresis

authors： Abuabdou A,Rosenbaum ER,Usmani SZ,Barlogie B,Cottler-Fox M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Plasma exchange (PE) and double filtration plasmapheresis (DFPP) are known as effective treatment options for hyperviscosity syndrome (HVS) caused by Waldenstrom macroglobulinemia. Nonetheless, few data are available for the relation between the prescribed dose of apheresis and the reduction rate of target m...

journal_title：Journal of clinical apheresis

authors： Miyamoto Y,Hamasaki Y,Matsumoto A,Doi K,Noiri E,Nangaku M

更新日期：2018-10-01 00:00:00

abstract：:Staphylococcal protein A efficiently binds immunoglobulins and circulating immune complexes (CIC) and provides an effective medium to remove immunoglobulins and CICs from plasma while sparing albumin and most coagulation proteins. Although it activates the complement system its clinical use abrogates the need for plas...

journal_title：Journal of clinical apheresis

authors： Howe RB,Christie DJ

更新日期：1994-01-01 00:00:00

abstract：:The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related co...

journal_title：Journal of clinical apheresis

authors： Kiprov DD,Lippert R,Sandstrom E,Jones FR,Cohen RJ,Abrams D,Busch DF

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:There are several regimens used in hematopoietic stem cell (HSC) mobilization in multiple myeloma (MM). Cyclophosphamide (Cy) is one of the most commonly used agents, although it does not always result in collecting adequate number of CD34+ cells. Recently, cytarabine (Ara-C) has been proposed as potentially...

journal_title：Journal of clinical apheresis

authors： Bogucka-Fedorczuk A,Czyz A,Kalicińska E,Sawicki M,Laszkowska-Lewko M,Wicherska-Pawłowska K,Rybka J,Szeremet A,Prajs I,Szymczak D,Wróbel T

更新日期：2020-08-01 00:00:00

abstract：:Current management of heparin-induced thrombocytopenia (HIT) involves prompt discontinuation of all heparin products and concomitant initiation of a direct thrombin or anti-Xa inhibitor for anticoagulation. In the setting of HIT complicated by an urgent need for cardiopulmonary bypass (CPB), the safety and the efficac...

journal_title：Journal of clinical apheresis

authors： Cho JH,Parilla M,Treml A,Wool GD

更新日期：2019-02-01 00:00:00

abstract：:Antisynthetase syndrome (ASS) is a rare condition characterized by interstitial lung disease (ILD), inflammatory myositis, fever, Raynaud phenomenon, mechanic's hand, and inflammatory polyarthritis in the setting of antibodies to amino acyl-transfer RNA synthetases, with anti-Jo-1 antibody being the most common. Progn...

journal_title：Journal of clinical apheresis

authors： Omotoso BA,Ogden MI,Balogun RA

更新日期：2015-12-01 00:00:00

abstract：:A "snapshot" survey of physician coverage for evaluation and supervision of therapeutic apheresis procedures shows significant variation in current clinical practice between 39 blood center-and 41 non-blood center-based programs. Whereas 56% of blood center-based programs usually require physician's "in person" evalua...

journal_title：Journal of clinical apheresis

authors： Woll JE

更新日期：1995-01-01 00:00:00