Improved red cell quality after erythroplasmapheresis with MCS-3P.

abstract：:Plerixafor in combination with granulocyte-colony stimulating factor (G-CSF) is approved for autologous stem cell mobilization in poor mobilizing patients with multiple myeloma or malignant lymphoma. The purpose of this study was to evaluate efficacy and safety of plerixafor in an immediate rescue approach, administra...

journal_title：Journal of clinical apheresis

authors： Worel N,Fritsch G,Agis H,Böhm A,Engelich G,Leitner GC,Geissler K,Gleixner K,Kalhs P,Buxhofer-Ausch V,Keil F,Kopetzky G,Mayr V,Rabitsch W,Reisner R,Rosskopf K,Ruckser R,Zoghlami C,Zojer N,Greinix HT

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:There are several regimens used in hematopoietic stem cell (HSC) mobilization in multiple myeloma (MM). Cyclophosphamide (Cy) is one of the most commonly used agents, although it does not always result in collecting adequate number of CD34+ cells. Recently, cytarabine (Ara-C) has been proposed as potentially...

journal_title：Journal of clinical apheresis

authors： Bogucka-Fedorczuk A,Czyz A,Kalicińska E,Sawicki M,Laszkowska-Lewko M,Wicherska-Pawłowska K,Rybka J,Szeremet A,Prajs I,Szymczak D,Wróbel T

更新日期：2020-08-01 00:00:00

abstract：:Photopheresis has become a key component in the therapeutic armamentarium of cutaneous T-cell lymphoma, graft-versus-host disease following stem cell transplant, and allograft rejection of solid organs such as heart. Although it is considered a new treatment modality in its present form, the field of phototherapy date...

journal_title：Journal of clinical apheresis

authors： Marques MB,Tuncer HH

更新日期：2006-04-01 00:00:00

abstract：:Granulocyte-colony stimulating factor (G-CSF) mobilizes and increases the amount of hematopoietic stem cells in peripheral blood, enabling its harvest by few apheresis procedures. The pegylated G-CSF has longer half-life and is given once only, which is more comfortable for patients, whereas the non-pegylated requires...

journal_title：Journal of clinical apheresis

authors： Kuan JW,Su AT,Leong CF

更新日期：2017-12-01 00:00:00

abstract：:Extracorporeal photopheresis (ECP) has been shown to be clinically effective in the treatment of many T cell-mediated conditions. ECP's mechanism of action includes the induction of apoptosis and the release of pro-inflammatory cytokines. Recently, we have observed early lymphoid apoptosis, detectable immediately post...

journal_title：Journal of clinical apheresis

authors： Bladon J,Taylor P

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Myeloid-derived leucocytes, a major source of inflammatory cytokines, play an important role in the exacerbation of ulcerative colitis (UC). Selective depletion of myeloid leucocytes by adsorptive granulomonocytapheresis (GMA) with an Adacolumn should alleviate inflammation and promote remission. However, th...

journal_title：Journal of clinical apheresis

authors： Li N,Mao J,Tang H,Zhu L,Tan X,Bi J,Wu H,Chen X,Wang Y

更新日期：2020-08-01 00:00:00

abstract：:The supply of deceased donor kidneys is inadequate to meet demand. To expand the pool of potential donors, ABO-incompatible transplants from living donors have been performed. We present the Mayo Clinic experience with such transplants. Enrollment was open to patients when the only available potential living kidney do...

journal_title：Journal of clinical apheresis

authors： Winters JL,Gloor JM,Pineda AA,Stegall MD,Moore SB

更新日期：2004-01-01 00:00:00

abstract：:Modern techniques of mechanical hemapheresis have made it possible to selectively remove vast quantities of lymphocytes and plasma immunoglobulins, and the concentration of these substances in donor blood can fall below the normal range. It is feared that this may lead to immunosuppression; a condition associated in s...

journal_title：Journal of clinical apheresis

authors： Strauss RG

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

更新日期：2016-12-01 00:00:00

abstract：:For therapeutic plasma exchange (TPE), continuous flow separators are known to be efficient as exemplified by Fresenius AS104 and COBE Spectra. The AS104 uses an interface monitoring system in the centrifuge during TPE, whereas Spectra uses computer algorithms to establish the plasma-cell interface. To determine the p...

journal_title：Journal of clinical apheresis

authors： Burgstaler EA,Pineda AA

更新日期：2001-01-01 00:00:00

abstract：:Two patients suffering from allergic bronchial asthma who showed no improvement despite six and four weeks, respectively, of drug therapy were successfully treated with therapeutic plasma exchange. The first patient had no attacks over a period of five months, and the other patient had none for over one year. Although...

journal_title：Journal of clinical apheresis

authors： Bambauer R,Jutzler GA,Micka K,Austgen M,Schlimmer P,Trendelenburg F

更新日期：1984-01-01 00:00:00

abstract：:This study was undertaken to evaluate the relationship between the time to recovery of peripheral blood counts and CD34+ cells in the peripheral blood (PB) and apheresis collections of patients undergoing intensive chemotherapy followed by rhG-CSF. Twenty-three patients with a median age of 42 years (range 17-64) with...

journal_title：Journal of clinical apheresis

authors： Williams O,Demirer T,Lilleby K,Buckner CD,Bensinger WI

更新日期：1998-01-01 00:00:00

abstract：:Extracorporeal photopheresis (ECP) in young pediatric patients has a risk for procedural hypotension and anemia due to extracorporeal fluid shifts. A standard mitigation policy in these patients is to prime the device with packed red blood cells (RBC) or whole blood. We now report multiple episodes of hemolysis while ...

journal_title：Journal of clinical apheresis

authors： Cooling L,Thompson T,Downs T,Abusin G,Yanik G

更新日期：2019-12-01 00:00:00

abstract：:This study examined the incidence and predictors of peripheral blood stem cell (PBSC) mobilization failure in patients with multiple myeloma (MM). Retrospective data for 104 patients who received granulocyte colony-stimulating factor (G-CSF) alone or with cyclophosphamide as mobilization regimens were analyzed. The ra...

journal_title：Journal of clinical apheresis

authors： Jung SH,Yang DH,Ahn JS,Kim YK,Kim HJ,Lee JJ

更新日期：2014-12-01 00:00:00

abstract：:Idiopathic inflammatory demyelinating diseases (IIDDs) of the central nervous system, of which multiple sclerosis is the prototype, represent a family of monophasic, recurrent or progressive diseases with overlapping clinical and pathological manifestations. While most patients recover spontaneously or following a bri...

journal_title：Journal of clinical apheresis

authors： Weinshenker BG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Hereditary thrombotic thrombocytopenic purpura, also called Upshaw-Schulman syndrome (USS), is a rare disease caused by genetic mutations in the ADAMTS13 gene, which severely decrease the activity of ADAMTS13, a metalloprotease that cleaves von Willebrand factor multimers (VWF). Genotypically identical patie...

journal_title：Journal of clinical apheresis

authors： Kovarova P,Hrdlickova R,Blahutova S,Cermakova Z

更新日期：2019-02-01 00:00:00

abstract：:Mobilized PBSC are the main source for allogeneic HSCT. We aimed to evaluate factors that affect CD34+ cell yield including the donor's age, gender, BSA, processed blood volume and the method of G-CSF dose calculation. Data from 170 healthy donors were analyzed. The concentration of CD34+ cells in the peripheral blood...

journal_title：Journal of clinical apheresis

authors： Machaczka M,Hägglund H,Staver E,Joks M,Hassan M,Wahlin BE,Axdorph Nygell U

更新日期：2017-12-01 00:00:00

abstract：:In December 2007, the FDA issued a guidance document recommending that apheresis cell separators be configured with a postdonation platelet count target of > or =100,000 platelets/microL. Currently, our Trima Accel apheresis cell separators are configured with a postdonation platelet count target of > or =50,000 plate...

journal_title：Journal of clinical apheresis

authors： Alex J,Roberts B,Raife T

更新日期：2009-01-01 00:00:00

abstract：:Targeted extracorporeal granulocyte and monocyte apheresis (GMA) has produced clinical efficacy together with down modulation of specific inflammatory cytokines in patients with ulcerative colitis (UC). This study was to investigate if preoperative GMA produces immunological effect on dysregulated immune activity afte...

journal_title：Journal of clinical apheresis

authors： Bamba T,Yamamoto T,Umegae S,Matsumoto K

更新日期：2014-04-01 00:00:00

abstract：:Although rituximab (RTX) is a promising therapeutic agent for treating steroid-resistant nephrotic syndrome (SRNS) resistant to various immunosuppressive agents, some patients have shown resistance to RTX. We report the case of a patient with RTX-resistant nephrotic syndrome and SRNS who was successfully treated with ...

journal_title：Journal of clinical apheresis

authors： Takakura M,Shimizu M,Mizuta M,Inoue N,Tasaki Y,Ohta K,Furuichi K,Wada T,Yachie A

更新日期：2018-06-01 00:00:00

abstract：:The infusion of high-dose (275 mg/kg body weight) immune globulin intravenous (IGIV) after 466 plasma exchanges in 64 patients with autoimmune disease was studied. Side effects occurred during 15% of IGIV infusions. For the most part they were transient and mild, and could be controlled by slowing the infusion rate. T...

journal_title：Journal of clinical apheresis

authors： Dau PC

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:In organ transplantation, apheresis is frequently used for removal of anti-HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi-selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to reach post-treatment objectives is also unknown. ...

journal_title：Journal of clinical apheresis

authors： Jambon F,Merville P,Guidicelli G,Taton B,De Précigout V,Couzi L,Moreau K,Visentin J

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Factors affecting progenitor cell mobilization in patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) are incompletely understood. The aim of this retrospective study was to determine which factors are crucial for effective mobilization and collection of autologous peripheral blood stem ce...

journal_title：Journal of clinical apheresis

authors： Han X,Ma L,Zhao L,He X,Liu P,Zhou S,Yang J,Qin Y,Yang S,Yao J,Shi Y

更新日期：2012-01-01 00:00:00

abstract：:The literature on the use of therapeutic apheresis is often criticized for the preponderance of low to very low quality evidence. Shehata et al. examined the apheresis literature published between 1976 and 1999 and found a lack of randomized controlled trials with those identified demonstrating significant limitations...

journal_title：Journal of clinical apheresis

authors： Winters JL

更新日期：2013-02-01 00:00:00

abstract：:Staphylococcal protein A efficiently binds immunoglobulins and circulating immune complexes (CIC) and provides an effective medium to remove immunoglobulins and CICs from plasma while sparing albumin and most coagulation proteins. Although it activates the complement system its clinical use abrogates the need for plas...

journal_title：Journal of clinical apheresis

authors： Howe RB,Christie DJ

更新日期：1994-01-01 00:00:00

abstract：:In-line leukocyte reduction filters (LRF) are available for use with an automated plateletpheresis (PPH) system. Initially, 62% of PPH units produced with such a filter (LRF6, N = 29) had postfiltration (POF) white blood cell (WBC) counts < 5 x 10(6), with a mean POF WBC of 42 x 10(6). In an attempt to decrease POF WB...

journal_title：Journal of clinical apheresis

authors： Drew MJ,Hodges J

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The ability to cryopreserve a portion of the cells treated during extracorporeal photopheresis (ECP) would improve therapy logistics, particularly for pediatric patients, by allowing multiple therapeutic doses to be collected from a single apheresis session. However, the effect of cryopreservation on ECP-tre...

journal_title：Journal of clinical apheresis

authors： Radwanski K,Heber C,Min K

更新日期：2015-06-01 00:00:00

abstract：:Bone marrow (BM) damage after previous chemotherapy, such as that involving alkylating agents, and radiation therapy alone cannot explain poor hematopoietic progenitor cell mobilization. We examined the T lymphocytes of BM in 67 autologous peripheral blood stem cell transplant (auto-PBSCT) patients with non-Hodgkin ly...

journal_title：Journal of clinical apheresis

authors： Oka S,Nohgawa M

更新日期：2020-07-28 00:00:00

abstract：BACKGROUND:Autologous stem cell transplantation (auto-SCT) is a treatment approach in non-Hodgkin lymphoma (NHL) patients. The options for mobilization of CD34+ cells to support high-dose therapy are granulocyte-colony stimulating factors (G-CSFs) alone or after chemotherapy. Limited data exist on the efficacy of lipeg...

journal_title：Journal of clinical apheresis

authors： Partanen A,Turunen A,Valtola J,Vasala K,Ågren L,Penttilä K,Pyörälä M,Kuittinen T,Mäntymaa P,Pelkonen J,Jantunen E,Varmavuo V

更新日期：2020-08-01 00:00:00

abstract：:Folinic acid (FA) has been reported to expand the pool of peripheral blood stem cells (PBSC) after chemotherapy. We evaluated the efficacy of FA for harvesting PBSC following cytotoxic chemotherapy in 4 patients with acute leukemia. After achieving a complete remission (CR), 3 courses of chemotherapy for a consolidati...

journal_title：Journal of clinical apheresis

authors： Teshima T,Harada M,Takamatsu Y,Inaba S,Kondo S,Akashi K,Okamura T,Niho Y

更新日期：1992-01-01 00:00:00