Method for the safe and rapid pretransfusion warming of stored blood: an in vitro and in vivo evaluation of a radiofrequency (RF) instrument.

Abstract:

:Inadvertent hypothermia due to massive infusion of stored blood can be prevented by pretransfusion warming. One approach is the heating of individual packs by means of electromagnetic conduction, which is a method safely used over the last 25 years. The prototype instrument, which has now been re-engineered, can effectively raise the temperature of a unit of blood to approximately 33 degrees C in less than 3 minutes. Using this new model, we found, in vitro, a modest increase in free plasma haemoglobin, but this was not accompanied by any change in potassium or lactic dehydrogenase levels and the mean red cell fragility was unaltered. In vivo, the survival of autologous red cells that had been stored for 33 days and then infused as a concentrate, having a mean haematocrit of 0.60, was measured at 24 hours and 21 days. Each donor acted as his own control. In paired studies, pretransfusion radiofrequency heating was shown to have no deleterious effect when compared to measurements using the unwarmed blood pack. It is concluded that this method can be recommended as safe.

journal_name

J Clin Apher

authors

Harrison GG,Bird AR,Jacobs P,Coghlan P,Byrne MJ,Ozinsky J,Besseling JL

doi

10.1002/jca.2920070105

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

12-7

issue

1

eissn

0733-2459

issn

1098-1101

journal_volume

7

pub_type

临床试验,杂志文章,随机对照试验
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    authors: Nguyen TH,Bach KQ,Vu HQ,Nguyen NQ,Duong TD,De Reys S,Wheeler J

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  • Therapeutic plasma exchange in recurrent focal segmental glomerulosclerosis following transplantation.

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  • Protein A immunoadsorption treatment in hematology: an overview.

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  • Peripheral blood stem cell transplantation: impact on procedure load and workload in an apheresis unit.

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  • Thrombopoietin serum levels at the start of mobilization, collection, and transfusion of autologous peripheral blood stem cells.

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    更新日期:1999-01-01 00:00:00

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    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章

    doi:10.1002/jca.21757

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    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1098-1101(1996)11:3<149::AID-JCA6>3.

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    更新日期:1996-01-01 00:00:00

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    journal_title:Journal of clinical apheresis

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    doi:10.1002/jca.21441

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  • Surviving peer review.

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    authors: Weinstein R

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    journal_title:Journal of clinical apheresis

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    更新日期:2017-12-01 00:00:00

  • Plasma exchange for renal disease: evidence and use 2011.

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    journal_title:Journal of clinical apheresis

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    doi:10.1002/jca.21221

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    更新日期:2012-01-01 00:00:00

  • Clinically relevant hypokalaemia, hypocalcaemia, and loss of hemoglobin and platelets during stem cell apheresis.

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    journal_title:Journal of clinical apheresis

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    authors: Schlenke P,Frohn C,Steinhardt MM,Kirchner H,Klüter H

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    journal_title:Journal of clinical apheresis

    pub_type: 杂志文章,评审

    doi:10.1002/jca.2920070307

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  • Successful management of a Jehovah's Witness with thrombotic thrombocytopenic purpura unwilling to be treated with therapeutic plasma exchange.

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    pub_type: 杂志文章

    doi:10.1002/jca.20150

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  • Debunking superstition: Analyzing the cloud phenomenon in apheresis-Results of a 35-month study.

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    pub_type: 历史文章,杂志文章,评审

    doi:10.1002/jca.20089

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