Successful management of a Jehovah's Witness with thrombotic thrombocytopenic purpura unwilling to be treated with therapeutic plasma exchange.

abstract：:Blood component donations by apheresis have become more common in modern blood transfusion practices. We compared three apheresis instruments (Fenwal Amicus, Fresenius COM.TEC, and Trima Accel) with regard to platelet (PLT) yield, collection efficiency (CE), and collection rate (CR). The single-needle or double-needle...

journal_title：Journal of clinical apheresis

authors： Keklik M,Eser B,Kaynar L,Sivgin S,Keklik E,Solmaz M,Ozturk A,Buyukoglan R,Yay M,Cetin M,Unal A

更新日期：2015-06-01 00:00:00

abstract：:Either bone marrow or peripheral blood may be harvested to provide hematopoietic stem cells (HSC) for autologous transplantation. Both, however, comprise heterogeneous cell populations. The HSC necessary for successful engraftment constitute a very small fraction of the cells harvested. After collection, the harvested...

journal_title：Journal of clinical apheresis

authors： Rowley SD

更新日期：1992-01-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a recognized complication of malignant hypertension (HTN). Such patients have blood pressures > or = 200/140 mmHg but the condition is defined by the presence of papilledema and is frequently complicated by acute renal failure. Here we report two patients with severe HTN (systolic >...

journal_title：Journal of clinical apheresis

authors： Egan JA,Bandarenko N,Hay SN,Paradowski L,Goldberg R,Nickeleit V,Brecher ME

更新日期：2004-01-01 00:00:00

abstract：:Extra-corporeal photopheresis (ECP) is known as safe ultimate treatment option for chronic lung allograft dysfunction (CLAD). Here, we report the first case of ECP as "second-line" immunomodulatory therapy early post-transplant in an adult patient undergoing lung transplantation for severe chronic thromboembolic pulmo...

journal_title：Journal of clinical apheresis

authors： Steinack C,Robinson CA,Nägeli M,Inci I,Benden C

更新日期：2020-08-24 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a rare but severe disorder characterized by hemolytic anemia, thrombocytopenia, fever, renal failure, and neurologic manifestations. Plasma exchange is the most effective treatment for this condition reducing mortality from 90% in untreated patients to 10%. However, infecti...

journal_title：Journal of clinical apheresis

authors： Illoh OC

更新日期：2007-01-01 00:00:00

abstract：:Current management of heparin-induced thrombocytopenia (HIT) involves prompt discontinuation of all heparin products and concomitant initiation of a direct thrombin or anti-Xa inhibitor for anticoagulation. In the setting of HIT complicated by an urgent need for cardiopulmonary bypass (CPB), the safety and the efficac...

journal_title：Journal of clinical apheresis

authors： Cho JH,Parilla M,Treml A,Wool GD

更新日期：2019-02-01 00:00:00

abstract：:Plerixafor in combination with granulocyte-colony stimulating factor (G-CSF) is approved for autologous stem cell mobilization in poor mobilizing patients with multiple myeloma or malignant lymphoma. The purpose of this study was to evaluate efficacy and safety of plerixafor in an immediate rescue approach, administra...

journal_title：Journal of clinical apheresis

authors： Worel N,Fritsch G,Agis H,Böhm A,Engelich G,Leitner GC,Geissler K,Gleixner K,Kalhs P,Buxhofer-Ausch V,Keil F,Kopetzky G,Mayr V,Rabitsch W,Reisner R,Rosskopf K,Ruckser R,Zoghlami C,Zojer N,Greinix HT

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:In organ transplantation, apheresis is frequently used for removal of anti-HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi-selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to reach post-treatment objectives is also unknown. ...

journal_title：Journal of clinical apheresis

authors： Jambon F,Merville P,Guidicelli G,Taton B,De Précigout V,Couzi L,Moreau K,Visentin J

更新日期：2020-11-30 00:00:00

abstract：:Excess free iodide in the blood (ingested or injected) may cause thyrotoxicosis in patients at risk. Iodinated contrast solutions contain small amounts of free iodide and may be of significance for patients affected by Graves' disease, multinodular goiter or living in areas of iodine deficiency. Herein, we report a 57...

journal_title：Journal of clinical apheresis

authors： Pasimeni G,Caroli F,Spriano G,Antonini M,Baldelli R,Appetecchia M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The ability to cryopreserve a portion of the cells treated during extracorporeal photopheresis (ECP) would improve therapy logistics, particularly for pediatric patients, by allowing multiple therapeutic doses to be collected from a single apheresis session. However, the effect of cryopreservation on ECP-tre...

journal_title：Journal of clinical apheresis

authors： Radwanski K,Heber C,Min K

更新日期：2015-06-01 00:00:00

abstract：:Peripheral blood stem cells (PBSC) reinfusion appears to hasten hematologic reconstitution following myeloablative therapy. While procurement of PBSC adds apheresis procedures, rapid engraftment could decrease the demand for platelet transfusions. To determine the impact of PBSC collection on workload in our apheresis...

journal_title：Journal of clinical apheresis

authors： Ghalie R,McLeod B,Richman C,Valentino L,Manson S,Netols C,Kaizer H

更新日期：1992-01-01 00:00:00

abstract：:The issues of providing quality blood products and maintaining donor safety are primary aims of blood transfusion services. A comprehensive quality system should be in place to fulfill these aims, which can be attained through strict adherence to the established standard operating procedures (SOPs). The Drugs and Cosm...

journal_title：Journal of clinical apheresis

authors： Chaudhary R,Sekhar Das S,Agarwal P,Shanker Shukla J

更新日期：2005-07-01 00:00:00

abstract：INTRODUCTION:Nanoscale particle-based drug delivery systems like long circulating liposomal doxorubicin show unique pharmacokinetic properties and improved toxicity profiles. Liposomal doxorubicin accumulates in tumor tissue due to the enhanced permeation and retention effect, but only a small fraction of a total dose ...

journal_title：Journal of clinical apheresis

authors： Pütz G,Schmah O,Eckes J,Hug MJ,Winkler K

更新日期：2010-01-01 00:00:00

abstract：:The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related co...

journal_title：Journal of clinical apheresis

authors： Kiprov DD,Lippert R,Sandstrom E,Jones FR,Cohen RJ,Abrams D,Busch DF

更新日期：1985-01-01 00:00:00

abstract：:Acute thrombotic thrombocytopenic purpura (TTP) occurred in three patients following abdominal surgeries. One patient underwent extensive lysis for intestinal adhesions with bowel resection, another cholecystectomy for acute cholecystitis, and the third right colectomy and partial intestinal resection for colon cancer...

journal_title：Journal of clinical apheresis

authors： Chang JC,El-Tarabily M,Gupta S

更新日期：2000-01-01 00:00:00

abstract：:In-line leukocyte reduction filters (LRF) are available for use with an automated plateletpheresis (PPH) system. Initially, 62% of PPH units produced with such a filter (LRF6, N = 29) had postfiltration (POF) white blood cell (WBC) counts < 5 x 10(6), with a mean POF WBC of 42 x 10(6). In an attempt to decrease POF WB...

journal_title：Journal of clinical apheresis

authors： Drew MJ,Hodges J

更新日期：1995-01-01 00:00:00

abstract：:"Leukocyte-depleted" platelet concentrates (LD-SDPC) were prepared by cotton-wool and by polyester filtration of "leukocyte-poor" PC collected by the elutriation technique. The storage characteristics of LD-SDPC were comparable to those of the filtered pools of multiple donor platelet concentrates (LD-MDPC). However, ...

journal_title：Journal of clinical apheresis

authors： Elias MK,de Wolf JT,Blom N,Rijskamp L,Halie RM,Smit Sibinga CT

更新日期：1991-01-01 00:00:00

abstract：:Because the administration of hematopoietic growth factors and the use of stem cell support often fails to alleviate the neutropenic phase induced by cytotoxic drugs, several investigators have attempted to expand ex vivo hematopoietic progenitors for clinical use. These attempts have clearly shown that the cultured c...

journal_title：Journal of clinical apheresis

authors： Estrov Z,Huh YO,Ginsberg CF,Harris D,Van Q,Mirza NQ,Talpaz M,Korbling M

更新日期：2002-01-01 00:00:00

abstract：:Extracorporeal photopheresis (ECP) in young pediatric patients has a risk for procedural hypotension and anemia due to extracorporeal fluid shifts. A standard mitigation policy in these patients is to prime the device with packed red blood cells (RBC) or whole blood. We now report multiple episodes of hemolysis while ...

journal_title：Journal of clinical apheresis

authors： Cooling L,Thompson T,Downs T,Abusin G,Yanik G

更新日期：2019-12-01 00:00:00

abstract：:Management of aTTP in patients who refuse or are intolerant to plasma remains challenging, but new drugs can be implemented with success. A 39-year-old woman presented to the Emergency department for bruises at the upper and lower limbs together with worsening anemia and thrombocytopenia; PLASMIC score was seven, indi...

journal_title：Journal of clinical apheresis

authors： Perrone S,Passucci M,Ortu La Barbera E,Capriata M,Ferretti A,Mecozzi A,Giovangrossi P,Equitani F,Cimino G

更新日期：2021-01-18 00:00:00

abstract：:Thrombopoietin (TPO) serum levels in 14 patients (9 male and 5 female, mean age 36 years, range 16 to 55 years) with breast cancer (n = 5), testicular cancer (n = 7), or lymphoma (n = 2), undergoing high dose chemotherapy with peripheral blood stem cell (PBSC) transplantation, were evaluated at the first day of the mo...

journal_title：Journal of clinical apheresis

authors： Bojko P,Nowak N,Moritz T,Flasshove M,Harstrick A,Seeber S

更新日期：1999-01-01 00:00:00

abstract：:The purpose of this study is to determine whether immunoadsorption treatment using a dextran sulfate (DS) column can remove high-avidity anti-double-stranded DNA (anti-dsDNA) antibody from the blood of patients with systemic lupus erythematosus (SLE). Before and after each immunoadsorption therapy routine, titers of t...

journal_title：Journal of clinical apheresis

authors： Matsuki Y,Suzuki K,Kawakami M,Ishizuka T,Kawaguchi Y,Hidaka T,Nakamura H

更新日期：1996-01-01 00:00:00

abstract：:Complement-derived anaphylatoxin may be one of the causes of vascular injury and an indicator of activity in systemic lupus erythematosus (SLE). The present study examines the effectiveness of dextran sulfate (DS) column immunoadsorption treatment to remove anaphylatoxins (C3a, C4a, and C5a) from the blood of patients...

journal_title：Journal of clinical apheresis

authors： Matsuki Y,Suzuki K,Kawakami M,Ishizuka T,Hidaka T,Nakamura H

更新日期：1998-01-01 00:00:00

abstract：:Mobilized PBSC are the main source for allogeneic HSCT. We aimed to evaluate factors that affect CD34+ cell yield including the donor's age, gender, BSA, processed blood volume and the method of G-CSF dose calculation. Data from 170 healthy donors were analyzed. The concentration of CD34+ cells in the peripheral blood...

journal_title：Journal of clinical apheresis

authors： Machaczka M,Hägglund H,Staver E,Joks M,Hassan M,Wahlin BE,Axdorph Nygell U

更新日期：2017-12-01 00:00:00

abstract：:Targeted extracorporeal granulocyte and monocyte apheresis (GMA) has produced clinical efficacy together with down modulation of specific inflammatory cytokines in patients with ulcerative colitis (UC). This study was to investigate if preoperative GMA produces immunological effect on dysregulated immune activity afte...

journal_title：Journal of clinical apheresis

authors： Bamba T,Yamamoto T,Umegae S,Matsumoto K

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Therapeutic plasma exchange (TPE) may remove medications from the patient's plasma. Data is limited on the effect of TPE on unfractionated heparin (UFH). STUDY DESIGN AND METHODS:A retrospective review was performed of patients receiving TPE and continuous IV infusion UFH from 1/1/2008 to 6/30/2010. TPE wit...

journal_title：Journal of clinical apheresis

authors： Kaplan A,Raut P,Totoe G,Morgan S,Zantek ND

更新日期：2016-12-01 00:00:00

abstract：:Mobilization regimens for CD34+ cells have generally been judged successful based on the number of cells collected without evaluating mobilization separately from collection. Using retrospective data for patients who collected CD34+ cells on Total Therapy protocols 3a/3b (VTD-PACE) and Total Therapy 4/5 using a novel ...

journal_title：Journal of clinical apheresis

authors： Abuabdou A,Rosenbaum ER,Usmani SZ,Barlogie B,Cottler-Fox M

更新日期：2014-10-01 00:00:00

abstract：:Granulocyte-colony stimulating factor (G-CSF) mobilizes and increases the amount of hematopoietic stem cells in peripheral blood, enabling its harvest by few apheresis procedures. The pegylated G-CSF has longer half-life and is given once only, which is more comfortable for patients, whereas the non-pegylated requires...

journal_title：Journal of clinical apheresis

authors： Kuan JW,Su AT,Leong CF

更新日期：2017-12-01 00:00:00

abstract：:This study was undertaken to evaluate the relationship between the time to recovery of peripheral blood counts and CD34+ cells in the peripheral blood (PB) and apheresis collections of patients undergoing intensive chemotherapy followed by rhG-CSF. Twenty-three patients with a median age of 42 years (range 17-64) with...

journal_title：Journal of clinical apheresis

authors： Williams O,Demirer T,Lilleby K,Buckner CD,Bensinger WI

更新日期：1998-01-01 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) recurs in 30% of renal allograft transplants with graft loss in half of the cases. A humoral factor may be implicated. We report on the use of therapeutic plasma exchange (TPE) in 11 patients with recurrent FSGS post transplantation. Medical records from 1989-2000 were reviewe...

journal_title：Journal of clinical apheresis

authors： Shariatmadar S,Noto TA

更新日期：2002-01-01 00:00:00