Mechanisms of protective immunity against asexual blood stages of Plasmodium falciparum in the experimental host Saimiri.

abstract：:Ascorbate peroxidases (APX) are class I heme-containing enzymes that convert hydrogen peroxide into water molecules. The gene encoding APX has been characterized in 11 strains of Trypanosoma cruzi that are sensitive or resistant to benznidazole (BZ). Bioinformatic analysis revealed the presence of two complete copies ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nogueira FB,Rodrigues JF,Correa MM,Ruiz JC,Romanha AJ,Murta SM

更新日期：2012-06-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well as discussing ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Senger MR,Evangelista TCS,Dantas RF,Santana MVDS,Gonçalves LCS,de Souza Neto LR,Ferreira SB,Silva-Junior FP

更新日期：2020-10-02 00:00:00

abstract：:There is a general consensus that during chronic Trypanosoma cruzi infection, the host immune system induces complex processes to ensure the control of parasite growth while preserving the potential to mount and maintain a life-long controlled humoral and cellular immune response against the invading pathogen. This re...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sathler-Avelar R,Vitelli-Avelar DM,Teixeira-Carvalho A,Martins-Filho OA

更新日期：2009-07-01 00:00:00

abstract：:Two essential oils of Lippia alba (Mill.) N.E. Brown (Verbenacea), the carvone and citral chemotypes and 15 of their compounds were evaluated to determine cytotoxicity and antifungal activity. Cytotoxicity assays for both the citral and carvone chemotypes were carried out with tetrazolium-dye, which showed a dose-depe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mesa-Arango AC,Montiel-Ramos J,Zapata B,Durán C,Betancur-Galvis L,Stashenko E

更新日期：2009-09-01 00:00:00

abstract：:Triatoma brasiliensis is composed of at least four geographic populations (brasiliensis, melanica, macromelasoma, and juazeiro) that have distinct chromatic, morphologic, biologic and ecologic patterns, and genetic composition. Reciprocal crosses between all pairwise combinations were carried out in order to evaluate ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Costa J,Almeida CE,Dujardin JP,Beard CB

更新日期：2003-07-01 00:00:00

abstract：:Early Cretaceous flagellates with characters typical of trypanosomatids were found in the gut of sand fly larvae, as well as in surrounding debris, in Burmese amber. This discovery supports a hypothesis in which free-living trypanosomatids could have been acquired by sand fly larvae in their feeding environment and th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Poinar G Jr

更新日期：2007-08-01 00:00:00

abstract：:The Americas are presently experiencing the most serious known outbreak of Zika virus (ZIKV). Here, we present a novel set of analyses using environmental characteristics, vector mosquito distributions, and socioeconomic risk factors to develop the first map to detail global ZIKV transmission risk in multiple dimensio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Samy AM,Thomas SM,Wahed AA,Cohoon KP,Peterson AT

更新日期：2016-09-01 00:00:00

abstract：:In laboratory trials an aqueous solution of Piquerol A from Piqueria trinervia, collected in several regions of Mexico, showed a molluscicide action on the adults of eight different pulmonates snails species: Fossaria (Fossaria) humilis, F. (Bakerilymnaea) sp., Pseudosuccinea columella and Stagnicola attenuata from Me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cruz-Reyes A,Chavarin C,Campos Arias MP,Taboada J,Jimenez M

更新日期：1989-01-01 00:00:00

abstract：:This article presents an overview of the currently available drugs nifurtimox (NFX) and benznidazole (BZN) used against Trypanosoma cruzi, the aetiological agent of Chagas disease; herein we discuss their limitations along with potential alternatives with a focus on ergosterol biosynthesis inhibitors (EBI). These comp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Urbina JA

更新日期：2009-07-01 00:00:00

abstract：:A study was undertaken to search for DNA recombinant Schistosoma mansoni proteins responsible for eliciting an antibody response from the host at a very early phase after infection. A S. mansoni adult worm cDNA expression library was screened using pooled sera from baboons with four weeks of infection. Based on their ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kanamura HY,Hancock K,Rodrigues V,Damian RT

更新日期：2002-07-01 00:00:00

abstract：:Facilitated and improved by advances in molecular biology, techniques for the immunodiagnosis of schistosomiasis, including assays based on the detection of antigens circulating in the serum and/or excreted in the urine, have now reached the stage of multi-centre trials. There is a need to complement parasitological t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bergquist NR

更新日期：1992-01-01 00:00:00

abstract：:We report the first two cases of Trichosporon mycotoxinivorans infections in Latin America. We also conducted a literature review and a microbiological investigation, including that of clinical and environmental isolates. A 30-year-old man with chronic renal failure had disseminated infection after dialysis and a 15-y...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Almeida JN Jr,Francisco EC,Barberino MGMA,Silva LVRFD Filho,Brandão OM,Colombo AL,Padovan ACB

更新日期：2017-10-01 00:00:00

abstract：:BACKGROUND Fluctuations in climate have been associated with variations in mosquito abundance. OBJECTIVES To analyse the influence of precipitation, temperature, solar radiation, wind speed and humidity on the oviposition dynamics of Aedes aegypti in three distinct environmental areas (Brasília Teimosa, Morro da Conce...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos ICDS,Braga C,de Souza WV,de Oliveira ALS,Regis LN

更新日期：2020-01-01 00:00:00

abstract：:BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods that facilitat...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nunes AR,Alves BEB,Pereira HW,Nascimento YM,Morais IC,Fernandes JV,Araújo JM,Lanza DC

更新日期：2018-01-01 00:00:00

abstract：:Bacillus sphaericus produces at least two toxins which are highly toxic to mosquito larvae. The binary toxin, which is comprised of proteins of 51.4 and 41.9 kDa, is present in all highly insecticidal strains. The 100 kDa SSII-1 toxin is present in most highly insecticidal as well as the weakly insecticidal strains. T...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Davidson EW

更新日期：1995-01-01 00:00:00

abstract：:The present paper reports acuarioid nematodes recovered from avian hosts. A new species of the genus Schistorophus Railliet, 1916 is proposed based mainly on findings referring to ptilina, spicules and vagina. Ancyracanthopsis coronata (Molin, 1860) Chabaud & Petter, 1959 is referred again in Brazil since its proposit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pinto RM,Vicente JJ,Muniz-Pereira LC,Noronha D

更新日期：1999-11-01 00:00:00

abstract：:BACKGROUND The main strategy to control human malaria still relies on specific drug treatment, limited now by Plasmodium falciparum-resistant parasites, including that against artemisinin derivatives. Despite the large number of active compounds described in the literature, few of them reached full development against...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Penna-Coutinho J,Aguiar AC,Krettli\/ AU

更新日期：2018-12-06 00:00:00

abstract：:Neisseria meningitidis retains its ability to cause endemic and hiperendemic disease in human population living in any environment, as well as localized outbreaks and massive epidemics in civilians and military personnel. In Rio de Janeiro it has been reported in the 1990s as prolonged outbreak of serogroup B and at l...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barroso DE,Rebelo MC

更新日期：2007-09-01 00:00:00

abstract：:The alpha-glycerophosphate dehydrogenase (alpha-GPDH) activity in flight muscles of Panstrongylus megistus and Triatoma sordida, vectors of Chagas disease in Brazil, was studied. Both species showed higher enzymatic activities in fliers than in non-fliers insects. T. sordida exhibited a higher proportion of flier inse...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Soares RP,Santoro MM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) generally presents with a single or several localised cutaneous ulcers without involvement of mucous membranes. Ulcerated lesions are susceptible to secondary contamination that may slow the healing process. OBJECTIVE:This study verified the influence of non-parasitic wound infe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Antonio LF,Lyra MR,Saheki MN,Schubach AO,Miranda LFC,Madeira MF,Lourenço MCDS,Fagundes A,Ribeiro ÉADS,Barreto L,Pimentel MIF

更新日期：2017-09-01 00:00:00

abstract：:We analyzed prospectively 326 laboratory-confirmed, uncomplicated malarial infections (46.3% due to Plasmodium vivax, 35.3% due to P. falciparum, and 18.4% mixed-species infections) diagnosed in 162 rural Amazonians aged 5-73 years. Thirteen symptoms (fever, chills, sweating, headache, myalgia, arthralgia, abdominal p...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva-Nunes M,Ferreira MU

更新日期：2007-06-01 00:00:00

abstract：:There is no clear understanding of the outcome of reinfection in New World cutaneous leishmaniasis, and its role in the relationship to the development of protection or secondary disease. For this reason, reinfection experiments with homologous (Leishmania panamensis-L. panamensis) and heterologous (L. major-L. paname...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Osorio Y,Gonzalez SJ,Gama VL,Travi BL

更新日期：1998-05-01 00:00:00

abstract：:Analysis of zymograms with SDS-polyacrilamide gel electrophoresis containing gelatin as substrate, and performed on samples of haemolymph or fat body taken from Rhodnius prolixus inoculated or not with Enterobacter cloacae, demonstrated distinct patterns of protease activities: (i) in the haemolymph two proteases were...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feder D,Salles JM,Garcia ES,Azambuja P

更新日期：1998-11-01 00:00:00

abstract：:In 2008, we have celebrated the centenary of the discovery of Toxoplasma gondii.Although this ubiquitous protozoan can generate devastating damage in foetuses and newborns, its treatment is the only field in which we have made little progress, despite a huge body of research, and has not yet been validated. Pregnant w...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Peyron F

更新日期：2009-03-01 00:00:00

abstract：:There is no effective chemotherapy against diseases caused by Phytomonas sp., a plant trypanosomatid responsible for economic losses in major crops. We tested three triazolo-pyrimidine complexes [two with Pt(II), and another with Ru(III)] against promastigotes of Phytomonas sp. isolated from Euphorbia characias. The i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Magán R,Marín C,Salas JM,Barrera-Pérez M,Rosales MJ,Sánchez-Moreno M

更新日期：2004-10-01 00:00:00

abstract：:Dipteran polytene chromosomes provide an excellent model for understanding in species complexes, as well as for structural and functional cytogenetics. The status of species in the Culex pipiens complex is controversial and the use of polytene chromosomes for cytogenetic analysis in the subfamily Culicinae has been di...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Campos J,Andrade CF,Recco-Pimentel SM

更新日期：2003-04-01 00:00:00

abstract：:A simple and rapid method for differentiating the sibling species Biomphalaria tenagophila and Biomphalaria occidentalis by agarose gel electrophoresis (AGE) is described. Snail hemolymph is used as the test sample and the red coloration of the hemoglobin fraction permits visualization of the migration patterns withou...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bailey JB,Michelson EH,Paraense WL

更新日期：1986-07-01 00:00:00

abstract：:The sample consists of 226 skulls from the Atacameño cemetery of Coyo Oriente (639-910 AD), associated with the Tiwanaku period. The authors analyzed signs of acute trauma typically associated with violence, and the results were 12% of men and 9.9% of women displaying any type of lesion related to violence. In males, ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lessa A,de Souza SM

更新日期：2006-12-05 00:00:00

abstract：:Scientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the problem empirically....

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Neves K,Carneiro CF,Wasilewska-Sampaio AP,Abreu M,Valério-Gomes B,Tan PB,Amaral OB

更新日期：2020-10-23 00:00:00

abstract：:This paper presents a list of 131 Mallophaga type specimens deposited in the Werneck Collection of Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. It includes 69 holotypes, 62 allotypes, 683 paratypes, 1 syntype and 2 neoparatypes, distributed among 6 families and 35 genera. The types are listed with their respect...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardozo-de-Almeida M,Linardi PM,Costa J

更新日期：2003-03-01 00:00:00