Innate immunity and regulatory T-cells in human Chagas disease: what must be understood?

abstract：:Trypanosoma rangeli, a parasite generally considered non-pathogenic for man, is the second species of human trypanosome to be reported from the New World. The geographical distribution of T. rangeli often overlaps with that of T. cruzi, the same vertebrate and invertebrate hosts being infected. Their differentiation t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guhl F,Vallejo GA

更新日期：2003-06-01 00:00:00

abstract：:Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients with severe leptospir...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos CS,Azevedo EC,Soares LM,Carvalho MO,dos Santos AC,das Chagas AD Jr,da Silva CL,Chagas UM,dos Reis MG,Athanazio DA

更新日期：2013-06-01 00:00:00

abstract：:Brazilian studies involving entomological succession patterns in carcasses have been used to describe the necrophagous entomofauna of a determined municipality or region with forensic objectives. Following the same objectives, an ecological study with 10 calyptrate dipterans was carried out during the winter of 2007 a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa RR,Mello-Patiu CA,Ururahy-Rodrigues A,Barbosa CG,Queiroz MM

更新日期：2010-03-01 00:00:00

abstract：:Calomys callosus, Rengger 1830 (Rodentia, Cricetidae), a wild rodent found in Central Brazil, was studied to investigate its susceptibility to Toxoplasma gondii experimental infection and its humoral immune response against this protozoa. The electrophoretic profile of the serum proteins of C. callosus showed that IgG...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Favoreto-Júnior S,Ferro EA,Clemente D,Silva DA,Mineo JR

更新日期：1998-01-01 00:00:00

abstract：:Although human T-lymphotropic virus type I (HTLV-I) exhibits high genetic stability, as compared to other RNA viruses and particularly to human immunodeficiency virus (HIV), genotypic subtypes of this human retrovirus have been characterized in isolates from diverse geographical areas. These are currently believed not...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Segurado AA,Biasutti C,Zeigler R,Rodrigues C,Damas CD,Jorge ML,Marchiori PE

更新日期：2002-04-01 00:00:00

abstract：:Lymphatic filariasis caused by nematode parasites Wuchereria bancrofti or Brugia malayi is a spectral disease and produces wide range of immune responses and varying levels of microfilaraemia in infected individuals. The relationship between the immune response of host and the developmental stage of the parasite as we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Athisaya Mary K,Hoti S,Paily K

更新日期：2006-05-01 00:00:00

abstract：:Several genes related to the ubiquitin (Ub)-proteasome pathway, including those coding for proteasome subunits and conjugation enzymes, are differentially expressed during the Schistosoma mansoni life cycle. Although deubiquitinating enzymes have been reported to be negative regulators of protein ubiquitination and sh...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pereira RV,Vieira HG,Oliveira VF,Gomes Mde S,Passos LK,Borges Wde C,Guerra-Sá R

更新日期：2014-02-01 00:00:00

abstract：:Rhodnius ecuadoriensis is the second most important vector of Chagas Disease (CD) in Ecuador. The objective of this study was to describe (and compare) the life cycle, the feeding and defecation patterns under laboratory conditions of two populations of this specie [from the provinces of Manabí (Coastal region) and Lo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Villacís AG,Arcos-Terán L,Grijalva MJ

更新日期：2008-11-01 00:00:00

abstract：:Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading causes of morbidity and death in Latin America. Although the pathogenesis of Chagas cardiomyopathy is incompletely understood, it may involve several mechanisms, including parasite-dependent my...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rassi A Jr,Marin JA Neto,Rassi A

更新日期：2017-03-01 00:00:00

abstract：:There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cruz ILR,Figueiredo-Carvalho MHG,Zancopé-Oliveira RM,Almeida-Paes R

更新日期：2018-01-01 00:00:00

abstract：:The great difficulties in treating people and animals suffering from cryptosporidiosis have prompted the development of in vitro experimental models. Due to the models of in vitro culture, new extracellular stages of Cryptosporidium have been demonstrated. The development of these extracellular phases depends on the t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Perez Cordón G,Marin C,Romero D,Rosales C,Sánchez Moreno M,Rosales MJ

更新日期：2007-08-01 00:00:00

abstract：:From May to August 1999, we evaluated 401 patients from a pediatric hospital of Havana City. One group was composed of 113 patients with diarrhea admitted to the Gastroenterology ward and a second consisted of 288 patients without diarrhea, admitted for other reasons, and hospitalized within the same time period. Thre...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Núñez FA,González OM,González I,Escobedo AA,Cordoví RA

更新日期：2003-06-01 00:00:00

abstract：:As pyrethroids are presently the favored group of insecticides to control triatomines, we performed a series of bioassays to determine the intrinsic activity of some of the main compounds used in the control campaigns, against five of the main species of triatomines to be controlled. Comparing the insecticides it can ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira Filho AM

更新日期：1999-01-01 00:00:00

abstract：:Results of studies on a larvicidal cyanobacterium that expresses a Bti cryIVD gene fusion are reported. Genetically altered Agmenellum quadruplicatum PR-6 is shown to be toxic to larvae of three major genera of disease-bearing mosquitos. Factors affecting expression of Bti genes in cyanobacteria are discussed. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Murphy RC,Stevens SE Jr

更新日期：1995-01-01 00:00:00

abstract：:A ribosome association factor (AF) was isolated from the yeast Sacchharomyces cerevisiae. Partial amino acid sequence of AF was determined from its fragment of 25 kDa isolated by treating AF with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-Bromoindolenine (BNPS-skatole). This sequence has a 86% identity to the product of th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Correia H,Medina R,Hernández A,Bustamante E,Chakraburtty K,Herrera F

更新日期：2004-11-01 00:00:00

abstract：:A study of the phlebotomine sand fly fauna was carried out in an endemic area of American visceral leishmaniasis (AVL) in the municipality of Porteirinha, in the Brazilian state of Minas Gerais. Captures were performed with CDC light traps in 7 districts, 5 days per month, during 2 consecutive years (January 2000 to D...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barata RA,Silva JC,Costa RT,Fortes-Dias CL,Silva JC,Paula EV,Prata A,Monteiro EM,Dias ES

更新日期：2004-08-01 00:00:00

abstract：:Several studies conducted all over the world have reported that the influenza virus is associated with great morbidity and mortality rates. In this study, we analyzed the incidence of the influenza virus between 2000 and 2003 in Curitiba. We studied 1621 samples obtained from outpatients and hospitalized patients of b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vidal LR,Siqueira MM,Nogueira MB,Raboni SM,Pereira LA,Takahashi GR,Rotta I,Debur Mdo C,Dalla-Costa LM

更新日期：2008-03-01 00:00:00

abstract：:This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients. Immunological evaluation was performed by measurement of secreted cytokines (interleukin IL-5, IL-10, IL-13, interferon-gamm...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Magalhães A,Miranda DG,Miranda RG,Araújo MI,Jesus AA,Silva A,Santana LB,Pearce E,Carvalho EM,Jesus AR

更新日期：2004-01-01 00:00:00

abstract：:Dissection of Lutzomyia longipalpis, captured in the São Luis focus of visceral Leishmaniasis revealed a 1.8% promastigote infection rate. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ryan L,Brazil RP

更新日期：1984-07-01 00:00:00

abstract：:A cross-sectional study for schistosomiasis was carried out in the localities of Aliança, Alegre and Coroatá (districts of Cururupu, São Bento and São João Batista, respectively) in the lowland of the state of Maranhão, after respectively 13, 11 and 4 mass treatments with oxamniquine in the period of ten years (1977-1...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cutrim RN,Coura JR

更新日期：1992-10-01 00:00:00

abstract：:An important point in paleoparasitology is the correct diagnosis of the origin of coprolites found in archaeological sites. The identification of human and animal coprolites, through the study of the shape, size, characteristics after rehydration, alimentary contents, and the presence of parasites, has proved to be ac...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira LF,Araújo A,Confalonieri U,Chame M

更新日期：1989-04-01 00:00:00

abstract：:[This corrects the article doi: 10.1590/0074-02760180073]. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors：

更新日期：2018-01-01 00:00:00

abstract：:The aim of the current paper was to study in the state of Sergipe the population distribution and interactions between two species of Biomphalaria, the snail vectors of Schistosoma mansoni in the northeastern Brazil. Data collected in 1969 showed that B. straminea, with only one exception, was limited to the semi-dry ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Figueiredo CC

更新日期：1989-07-01 00:00:00

abstract：:In Brazil, carbapenem-resistant Pseudomonas aeruginosa isolates are closely related to the São Paulo metallo-β-lactamase (SPM) Brazilian clone. In this study, imipenem-resistant isolates were divided in two sets, 2002/2003 and 2008/2009, analysed by pulsed field gel electrophoresis and tested for the Ambler class B me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cavalcanti FL,Almeida AC,Vilela MA,Morais MM,Morais Junior MA

更新日期：2012-05-01 00:00:00

abstract：:Clinical and laboratory evidence is reviewed which shows that there is a great deal of variation in the susceptibility of Schistosoma mansoni to oxamniquine. This variation occurs both among endemic regions and within endemic regions in Brazil and Kenya. It is genetically controlled. It is suggested that the parasite ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kinoti GK

更新日期：1987-01-01 00:00:00

abstract：:Ketoconazole, an azole antifungic drug which is already in the market has also been demonstrated to be active against Trypanosoma cruzi experimental infections. In this paper we confirmed the drug effect and investigated its range of activity against different T. cruzi strains naturally resistant or susceptible to bot...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brener Z,Cançado JR,Galvão LM,da Luz ZM,Filardi Lde S,Pereira ME,Santos LM,Cançado CB

更新日期：1993-01-01 00:00:00

abstract：:Trypanosoma cruzi acute infections often go unperceived, but one third of chronically infected individuals die of Chagas disease, showing diverse manifestations affecting the heart, intestines, and nervous systems. A common denominator of pathology in Chagas disease is the minimal rejection unit, whereby parasite-free...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira AR,Nascimento RJ,Sturm NR

更新日期：2006-08-01 00:00:00

abstract：:Studies based on shell or reproductive organ morphology and genetic considerations suggest extensive intraspecific variation in Biomphalaria snails. The high variability at the morphological and genetic levels, as well as the small size of some specimens and similarities between species complicate the correct identifi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vidigal TH,Dias Neto E,Spatz L,Nunes DN,Pires ER,Simpson AJ,Carvalho OS

更新日期：1998-01-01 00:00:00

abstract：:New alternative insecticides are necessary for the chemical control of head lice. In this study the fumigant knockdown time 50% (KT50) and repellency index (RI) of three aliphatic lactones was compared with two essential oils and DDVP, against permethrin-resistance Pediculus humanus capitis from Argentina. In the fumi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Toloza AC,Zygadlo J,Mougabure-Cueto G,Zerba E,Faillaci S,Picollo MI

更新日期：2006-02-01 00:00:00

abstract：:Epstein-Barr virus (EBV) plays a major role in liver pathology. Similar to other members of the herpesvirus family, EBV establishes a persistent infection in more than 90% of adults. The aim of this study was to evaluate the impact of EBV and chronic hepatitis C co-infection (HCV) on biochemical and immunological resp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Shoman S,Nabil M,Tabl A,Ghanem H,Kafrawy SE

更新日期：2014-09-01 00:00:00