Abstract：
:Iontophoresis of baclofen produced hyperpolarization and a decrease in input resistance in 32 neurons and no effect in 24 neurons of the ventral respiratory group in cats. Iontophoresed phaclofen antagonized the effect of baclofen, but had negligible effects on periodic fluctuations in membrane potential and spike activity in these neurons. The hyperpolarizing effect of baclofen persisted after iontophoresis of tetrodotoxin, suggesting that baclofen acted directly at the postsynaptic gamma-aminobutyric acid (GABA)B receptors.
journal_name
Brain Resjournal_title
Brain researchauthors
Haji A,Takeda Rdoi
10.1016/0006-8993(93)90832-8subject
Has Abstractpub_date
1993-09-17 00:00:00pages
294-8issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(93)90832-8journal_volume
622pub_type
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