Taste-potentiated odor aversion learning in rats with lesions of the insular cortex.

abstract：:The accessibility of macromolecules to the postnatal mammalian central nervous system is a subject of controversy and importance. One of the biologically important macromolecules in neural development, nerve growth factor (NGF), is thought to be unable to cross the blood-brain barrier in postnatal mammals. In this stu...

journal_title：Brain research

authors： Fabian RH,Hulsebosch CE

更新日期：1993-05-14 00:00:00

abstract：:A pair of neurons exhibiting postinhibitory rebound, if connected through reciprocally inhibitory chemical synapses, will exhibit a stable pattern of alternating bursts. If two such oscillating pairs, of similar but not identical properties are connected by means of an electrical synapse and an inhibitory chemical syn...

journal_title：Brain research

authors： Mulloney B,Perkel DH,Budelli RW

更新日期：1981-12-14 00:00:00

abstract：:The effects on fusimotor discharge rate of algesic agents (bradykinin, potassium chloride, histamine, 5-hydroxytryptamine) and lactic acid, applied by close arterial injection into triceps surae muscles, were investigated in decerebrate cats. Fusimotor discharge was recorded from filaments dissected free from otherwis...

journal_title：Brain research

authors： Jovanović K,Anastasijević R,Vuco J

更新日期：1990-06-25 00:00:00

abstract：:Responses to rotation in many vertical and horizontal planes were studied in electrically identified secondary vestibular neurons of alert cats. This report concerns secondary neurons that gave responses which could not be explained as due to a summation of semicircular canal inputs. These cells responded to sinusoida...

journal_title：Brain research

authors： Baker J,Goldberg J,Hermann G,Peterson B

更新日期：1984-02-27 00:00:00

abstract：:The non-cholinergic slow excitatory postsynaptic potential (EPSP) in the guinea pig inferior mesenteric ganglion (IMG) is believed to be mediated by substance P (SP). Yet, in ganglia of guinea pigs treated with capsaicin (50, 100, or 350 mg/kg, s.c.), a compound that depletes SP from sensory neurons, slow EPSPs were o...

journal_title：Brain research

authors： Peters S,Kreulen DL

更新日期：1984-06-11 00:00:00

abstract：:Caspases, a family of cysteine proteases, are widely activated in neurons and glia in the injured brain, a response thought to induce apoptosis. However, caspase activation in astrocytes following injury is not strongly associated with apoptosis. The present study investigates the potential role of caspase activation ...

journal_title：Brain research

authors： Aras R,Barron AM,Pike CJ

更新日期：2012-04-23 00:00:00

abstract：:Opioid receptor subtype antagonists differentially alter food intake under deprivation (24 h), glucoprivic (2-deoxy-D-glucose, 500 mg/kg, i.p.) or palatable (10% sucrose) conditions with mu (beta-funaltrexamine) and kappa (nor-binaltorphamine), but not delta1 ([D-Ala2,Leu5,Cys6]enkephalin) opioid antagonists reducing ...

journal_title：Brain research

authors： Ragnauth A,Ruegg H,Bodnar RJ

更新日期：1997-08-29 00:00:00

abstract：:In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive (disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic neurons. Here, we examined whether silencing of the hyperactive STN by chronic bilateral deep brain stimulation (DBS) increased the survival of midbrain do...

journal_title：Brain research

authors： Temel Y,Visser-Vandewalle V,Kaplan S,Kozan R,Daemen MA,Blokland A,Schmitz C,Steinbusch HW

更新日期：2006-11-20 00:00:00

abstract：:The postnatal development of acetylcholinesterase (AChE, EC 3.1.1.7) and NADH-diaphorase was examined in the caudate-putamen nucleus and substantia nigra of rats ranging from 3 to 90 days in age. From 3 to 15 days post partum islands of AChE and NADH-diaphorase activity were observed in the caudate-putamen nucleus. In...

journal_title：Brain research

authors： Butcher LL,Hodge GK

更新日期：1976-04-23 00:00:00

abstract：:The retrorubral field (RRF) contains numerous dopaminergic neurons and projects to the parvicellular reticular formation (RFp) of the medullary and pontomedullary brainstem, where many premotor neurons project to the orofacial motor nuclei. To know how the amygdala affects the RRF-RFp pathway in the rat, we first exam...

journal_title：Brain research

authors： Tsumori T,Qin Y,Yokota S,Niu JG,Yasui Y

更新日期：2010-01-08 00:00:00

abstract：:A site-specific antibody against the principal gap junctional protein in heart (connexin 43) was used to determine immunohistochemically the cellular localization of this protein in rat brain. Structures labelled with the antibody included gap junctional membranes between glial, ependymal, pial and arachnoid cells as ...

journal_title：Brain research

authors： Yamamoto T,Ochalski A,Hertzberg EL,Nagy JI

更新日期：1990-02-05 00:00:00

abstract：:Within the framework of the dual process model of recognition memory, prior work with event-related potentials (ERPs) has suggested that an early component, the FN400, is a correlate of familiarity while a later component, the Late Positive Complex (LPC), is a correlate of recollection. However, other work has questio...

journal_title：Brain research

authors： Wolk DA,Schacter DL,Lygizos M,Sen NM,Holcomb PJ,Daffner KR,Budson AE

更新日期：2006-06-22 00:00:00

abstract：:Developmental differences (9- to 15-year-olds) in effective connectivity in left hemisphere regions were examined using dynamic causal modeling (DCM) of functional magnetic resonance imaging (fMRI) data. Children completed spelling tasks in the visual and auditory modalities in which they were asked to determine if tw...

journal_title：Brain research

authors： Booth JR,Mehdiratta N,Burman DD,Bitan T

更新日期：2008-01-16 00:00:00

abstract：:The light green cells (LGCs) in the central nervous system of the pond snail Lymnaea stagnalis form a homogeneous group of neuroendocrine cells that are involved in the control of growth and metabolism. These cells are inhibited by dopamine and the neuropeptides APGWamide, FMRFamide and GGSLFRFamide. Thus, the LGCs fo...

journal_title：Brain research

authors： van Tol-Steye H,Lodder JC,Planta RJ,van Heerikhuizen H,Kits KS

更新日期：1997-11-28 00:00:00

abstract：:In a whole mount preparation of the hooded rat retina, stained with methylene blue, the ganglion cell density was counted over the retina. The density ranged from 6200-6500/sq.mm to 1000-1500/sq.mm. The area with a density higher than 6000/sq.mm was called the central area and was centered at about 1 mm (20 degrees) a...

journal_title：Brain research

authors： Fukuda Y

更新日期：1977-01-07 00:00:00

abstract：:Spatial learning and memory in rodents represent close equivalents of human episodic declarative memory, which is especially sensitive to cerebral aging, neurodegeneration, and various neuropsychiatric disorders. Many tests and protocols are available for use in laboratory rodents, but Morris water maze and radial-arm...

journal_title：Brain research

authors： Pooters T,Van der Jeugd A,Callaerts-Vegh Z,D'Hooge R

更新日期：2015-09-24 00:00:00

abstract：:Previous immunocytochemical studies have shown immunological differences between neurofilaments in axons and those in dendrites and perikarya of many mature neuron types: it is now known that non-phosphorylated epitopes are normally seen in cell bodies and dendrites of mature neurons, whereas phosphorylated epitopes a...

journal_title：Brain research

authors： Shaw G,Winialski D,Reier P

更新日期：1988-09-20 00:00:00

abstract：:Medial basal hypothalamic (MBH) 5 alpha-reductase activity was significantly blocked with a known inhibitor, Proscar (Finasteride), in pregnant rats while their open-field behavior was quantified during the last week of pregnancy. In control animals, open-field behavior significantly decreased (in a stair-step fashion...

journal_title：Brain research

authors： Lephart ED,Ladle DR,Jacobson NA,Rhees RW

更新日期：1996-11-11 00:00:00

abstract：:The ontogenic development of neurophysin has not been investigated so far. To study this problem, electron microscopic immunohistochemistry was performed on ultrathin sections of the posterior pituitary of foetal and newborn rats. A concomitant appearance of secretory granules and neurophysin was first noted in the po...

journal_title：Brain research

authors： Leclerc R,Pelletier G

更新日期：1977-07-01 00:00:00

abstract：:Synaptic plasma membrane preparations from brain tissue have endogenous Ca2+-dependent phospholipase A2 activity. Characterization of this activity revealed that it was maximally active at 10(-7)-10(-5) M Ca2+ and pH 7.0. The enzyme had a Km of 62.0 microM and a Vmax of 98.0 nmol/mg/h. Calmodulin and prostaglandin F2 ...

journal_title：Brain research

authors： Moskowitz N,Schook W,Puszkin S

更新日期：1984-01-09 00:00:00

abstract：:Ginseng is one of most extensively used traditional oriental medicines worldwide with beneficial efficacy on cognitive function disorders. Pharmacological researches on its active ingredient--ginsenoside Rg1 revealed that it can improve learning and memory potentially via modulating neurotransmission in the central ne...

journal_title：Brain research

authors： Liu ZJ,Zhao M,Zhang Y,Xue JF,Chen NH

更新日期：2010-05-28 00:00:00

abstract：:The main purpose of the present study was to determine whether specific lymphokines may be neurotrophic, by testing their effects on the survival of hippocampal neuronal cultures. Previous studies have shown that a variety of interleukins may be neurotrophic or neurotoxic, depending upon the culture conditions, as wel...

journal_title：Brain research

authors： Araujo DM,Cotman CW

更新日期：1993-01-08 00:00:00

abstract：:Both the somatosensory cerebral cortex and anterior pretectal nucleus (APT) have been shown to produce descending modulation of trigeminal (V) and spinal somatosensory neurone and reflex activities. Since the APT receives a direct projection from the somatosensory cortex, experiments were performed to compare the effe...

journal_title：Brain research

authors： Chiang CY,Dostrovsky JO,Sessle BJ

更新日期：1990-05-07 00:00:00

abstract：:Fetal exposure to dexamethasone (DEX) alters brain plasticity and cognitive functions during adulthood in a sex-dependent manner. The mechanisms underlying such long-lasting sex-dependent change of prenatal DEX is not well understood. The p73 gene plays an important role in brain development. It encodes for two protei...

journal_title：Brain research

authors： Abul M,Al-Bader MD,Mouihate A

更新日期：2019-03-15 00:00:00

abstract：:The structure of the plasma membrane of two neuronal cell types was quantitatively assessed in freeze-fracture replicas of rat cerebellar cortex from 2 to 73 postnatal days. The measurement of the number and size of intramembrane particles (IMP) in different regions of the Purkinje cells and of the granule cell showed...

journal_title：Brain research

authors： Garcia-Segura LM,Perrelet A

更新日期：1981-03-09 00:00:00

abstract：:Aspartame (L-aspartyl-L-phenylalanine methyl ester), an artificial low-calorie sweetener, was shown to dose-dependently inhibit L-[3H]glutamate binding to its N-methyl-D-aspartate-specific receptors. L-Aspartic acid, a major endogenous metabolite of aspartame, inhibited the binding more stronger than aspartame, while ...

journal_title：Brain research

authors： Pan-Hou H,Suda Y,Ohe Y,Sumi M,Yoshioka M

更新日期：1990-06-18 00:00:00

abstract：:Elevation of [K+]o for 30 s from 4 to 120 mM produced a fast and reversible depolarization and transient increase in [Ca2+]i in fura-2 loaded Retzius cells of the leech. The protein phosphatase inhibitor, okadaic acid, significantly slowed the return of [Ca2+]i toward baseline without affecting the amplitude of depola...

journal_title：Brain research

authors： Kleinhaus AL,Zeman RJ

更新日期：1994-07-11 00:00:00

abstract：:Three priming injections with the D1/D2 dopamine agonist apomorphine permits a challenge with the D2 agonist quinpirole to elicit robust contralateral rotation and ipsilateral striatal Fos expression in 6-hydroxydopamine lesioned rats. Pretreatment with NMDA glutamate antagonists MK-801 or CPP dose-dependently attenua...

journal_title：Brain research

authors： Pollack AE,Haisley EC

更新日期：2001-04-06 00:00:00

abstract：:The stimulatory effect of insulin-like growth factor I (IGF-I) on myelin basic protein (MBP) expression, a parameter for oligodendrocyte development, is mediated by the MAPK and PI3K signaling pathways. We have previously shown that the second messenger cAMP inhibits IGF-I-induced MAPK activation as well as MBP expres...

journal_title：Brain research

authors： Palacios N,Sánchez-Franco F,Fernández M,Sánchez I,Villuendas G,Cacicedo L

更新日期：2007-10-31 00:00:00

abstract：:Retrogradely labeled vestibulo-ocular neurons (VOR) that also stain with antibodies for the excitatory amino acid neurotransmitters glutamate (GLU-LI) or aspartate (ASP-LI) were studied. VOR neurons that contained GLU-LI or ASP-LI label were identified in the medial (MVN) and superior (SVN) vestibular nuclei, and cell...

journal_title：Brain research

authors： Kevetter GA,Hoffman RD

更新日期：1991-07-19 00:00:00