Abstract：
:Developmental differences (9- to 15-year-olds) in effective connectivity in left hemisphere regions were examined using dynamic causal modeling (DCM) of functional magnetic resonance imaging (fMRI) data. Children completed spelling tasks in the visual and auditory modalities in which they were asked to determine if two words were spelled the same from the first vowel onwards. Intrinsic (anatomical) connections were strongest from primary cortical regions to unimodal association areas - from Heschl's gyrus to superior temporal gyrus for the auditory spelling task and from calcarine to fusiform gyrus for the visual spelling task. The modulatory (experimental) effect for the visual spelling task from calcarine to superior temporal gyrus was stronger than all other effects from calcarine and this effect showed a developmental increase, suggesting automatic activation of phonology that increased with age. The modulatory effect from Heschl's gyrus to dorsal inferior frontal gyrus also showed a developmental increase, suggesting age-related increases in phonological segmentation in verbal working memory. All together, these results suggest that there are developmental increases in automatic access into brain regions involved in phonological processing in tasks that require orthographic processing.
journal_name
Brain Resjournal_title
Brain researchauthors
Booth JR,Mehdiratta N,Burman DD,Bitan Tdoi
10.1016/j.brainres.2007.10.080subject
Has Abstractpub_date
2008-01-16 00:00:00pages
78-89eissn
0006-8993issn
1872-6240pii
S0006-8993(07)02613-3journal_volume
1189pub_type
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