Contamination dose from photoneutron processes in bodily tissues during therapeutic radiation delivery.

Abstract:

:Dose to the total body from induced radiation resulting from primary exposure to radiotherapeutic beams is not detailed in routine treatment planning though this information is potentially important for better estimates of health risks including secondary cancers. This information can also allow better management of patient treatment logistics, suggesting better timing, sequencing, and conduct of treatment. Monte Carlo simulations capable of taking into account all interactions contributing to the dose to the total body, including neutron scattering and induced radioactivity, provide the most versatile and accurate tool for investigating these effects. MCNPX code version 2.2.6 with full IAEA library of photoneutron cross sections is particularly suited to trace not only photoneutrons but also protons and heavy ion particles that result from photoneutron interactions. Specifically, the MCNPX code is applied here to the problem of dose calculations in traditional (non-IMRT) photon beam therapy. Points of calculation are located in the head, where the primary irradiation has been directed, but also in the superior portion of the torso of the ORNL Mathematical Human Phantom. We calculated dose contributions from neutrons, protons, deutrons, tritons and He-3 that are produced at the time of photoneutron interactions in the body and that would not have been accounted for by conventional radiation oncology dosimetry.

journal_name

Med Phys

journal_title

Medical physics

authors

Difilippo F,Papiez L,Moskvin V,Peplow D,DesRosiers C,Johnson J,Timmerman R,Randall M,Lillie R

doi

10.1118/1.1612947

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

2849-54

issue

10

eissn

0094-2405

issn

2473-4209

journal_volume

30

pub_type

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