Abstract：
:Isatin is an endogenous indole present in mammalian tissues and fluids. This study was designed to test the effect of both acute stress (AS) and gender on isatin's levels in rat serum, heart and brain, using a HPLC-UV detection method. Basal brain isatin levels were higher in females than in males. AS resulted in increased isatin levels in male serum, heart and brain, and in female serum and heart, but not in the brain. The percentage increases were greater in males than in females in all three sources. After stress, there were significant correlations between isatin levels in the serum and the heart. However, there were no correlations between brain levels and those in the other sources. These results consolidate previous evidence that isatin levels are altered by stress and suggest that brain isatin is under separate control from that in the periphery.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Igosheva N,Matta S,Glover Vdoi
10.1016/j.physbeh.2003.11.005subject
Has Abstractpub_date
2004-02-01 00:00:00pages
665-8issue
5eissn
0031-9384issn
1873-507Xpii
S0031938403003366journal_volume
80pub_type
杂志文章abstract：:Guinea pig pups vocalized more and were more active during a 60-min period of isolation in a novel environment when injected SC with 50 micrograms of the corticotropin-releasing factor (CRF) antagonist, [D-Phe]CRF12-41, than when injected with saline vehicle only. More pups exhibited eye closing and extensive piloerec...
journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
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更新日期：2003-04-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1996-04-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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更新日期：2010-08-04 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1988-01-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章,评审
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更新日期：2006-08-30 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1991-05-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1996-09-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00092-1
更新日期：2003-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00233-u
更新日期：1995-03-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.07.034
更新日期：2005-01-31 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：2009-12-07 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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更新日期：2002-02-01 00:00:00
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更新日期：1985-04-01 00:00:00
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journal_title：Physiology & behavior
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更新日期：2015-07-01 00:00:00
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更新日期：2009-03-23 00:00:00
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pub_type： 杂志文章
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更新日期：2003-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：1997-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-10-24 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章,评审
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更新日期：2002-12-01 00:00:00
