Peripheral administration of a corticotropin-releasing factor antagonist increases the vocalizing and locomotor activity of isolated guinea pig pups.

Abstract:

:Guinea pig pups vocalized more and were more active during a 60-min period of isolation in a novel environment when injected SC with 50 micrograms of the corticotropin-releasing factor (CRF) antagonist, [D-Phe]CRF12-41, than when injected with saline vehicle only. More pups exhibited eye closing and extensive piloerection when injected with saline than when injected with the antagonist. Plasma levels of cortisol following testing were not affected by the injections. These results support the hypothesis that endogenous CRF contributes to the normal decline in vocalizing and locomotor activity that guinea pig pups show with continued isolation. The results also suggest that endogenous CRF plays a role in the eye closing and piloerection of isolated pups. The finding that the dose of the antagonist used altered behavior, yet was not sufficient to lower plasma cortisol levels, supports earlier evidence that the observed effects of CRF are not due to the actions of ACTH or glucocorticoids.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

McInturf SM,Hennessy MB

doi

10.1016/0031-9384(96)00091-1

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

707-10

issue

3

eissn

0031-9384

issn

1873-507X

pii

0031-9384(96)00091-1

journal_volume

60

pub_type

杂志文章
  • Olfactory and vomeronasal mediation of ultrasonic vocalizations in male mice.

    abstract::The effects of deafferentation of the vomeronasal, olfactory or both systems of male mice on ultrasonic vocalizations in response to a male or female stimulus were analyzed. Regardless of the technique used, disruption of the vomeronasal system led to consistent reductions in ultrasonic vocalizations. Each animal rece...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90097-x

    authors: Bean NJ

    更新日期:1982-01-01 00:00:00

  • Anaerobic training in hypoxia: A new approach to stimulate the rating of effort perception.

    abstract::This study compared subjective effort perception with objective physiological measures during high-intensive intermittent exercise performed in normoxia, moderate hypoxia (FiO2: 16.5%) and severe hypoxia (FiO2: 13.5%). Sixteen physically active subjects performed an equal training session on three different days. Trai...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.04.035

    authors: Álvarez-Herms J,Julià-Sánchez S,Gatterer H,Blank C,Corbi F,Pagès T,Burtscher M,Viscor G

    更新日期:2016-09-01 00:00:00

  • Genetic differences in female house mice in aggressive response to sex steroid hormone treatment.

    abstract::Male mice, genetically selected for aggression, characterized by short attack latency (SAL) or long attack latency (LAL), differ on several testosterone (T)-related parameters during ontogeny and adult age. The variation in aggressive behavior at adult age may be due to differences in degree of androgenization prenata...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90299-u

    authors: Compaan JC,van Wattum G,de Ruiter AJ,van Oortmerssen GA,Koolhaas JM,Bohus B

    更新日期:1993-11-01 00:00:00

  • Stress enhances the response to reward reduction but not food-motivated responding.

    abstract::The effect of a single exposure to foot shock stress on runway responding for food reinforcement was assessed in animals trained and tested with the same or changed reinforcement magnitude. Foot shock (30 1-s shocks, 1.0 mA) exerted no impact on runway responding in animals trained and tested with the same level of re...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00129-8

    authors: Bowers WJ,Attiast E,Amit Z

    更新日期:1999-11-01 00:00:00

  • Metabolic inter-organ relations by exercise of fed rat: carbohydrates, ketone body, and nitrogen compounds in splanchnic vessels.

    abstract::Fed rats were exercised until exhaustion by almost 65% VO2max on a treadmill. In 2.5 min after the exercise, blood was collected from various vessels of the splanchnic bed. Metabolites, glucose, lactate, ketone body, and nitrogencompounds in the plasma, were measured. Glucose excretion from the liver was increased by ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)00293-e

    authors: Hirai T,Minatogawa Y,Hassan AM,Kido R

    更新日期:1995-03-01 00:00:00

  • Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals.

    abstract:INTRODUCTION/PURPOSE:MicroRNAs (miRNAs), a class of non-coding RNAs, are involved in the regulation of gene expression and numerous biological processes, including inflammation and metabolism in obese populations. Emerging research indicates that physical activity provides health-related benefits in obesity-associated ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2018.09.011

    authors: Bao F,Slusher AL,Whitehurst M,Huang CJ

    更新日期:2018-12-01 00:00:00

  • The effects of isolation-rearing on sucrose consumption in rats.

    abstract::Three experiments examined the hypothesis that social isolation of weanling rats potentiates hedonic processes by examining the consumption of sucrose solutions. In the first experiment no differences in consumption were found between socially reared rats and isolation-reared rats allowed to consume sucrose in a famil...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00116-9

    authors: Hall FS,Humby T,Wilkinson LS,Robbins TW

    更新日期:1997-08-01 00:00:00

  • When a new technological product launching fails: A multi-method approach of facial recognition and E-WOM sentiment analysis.

    abstract::The dual aim of this research is, firstly, to analyze the physiological and unconscious emotional response of consumers to a new technological product and, secondly, link this emotional response to consumer conscious verbal reports of positive and negative product perceptions. In order to do this, biometrics and self-...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2018.04.023

    authors: Hernández-Fernández DA,Mora E,Vizcaíno Hernández MI

    更新日期:2019-03-01 00:00:00

  • Olfactory discrimination and incentive value of non copulating and sexually sluggish male rats.

    abstract::Some apparently healthy male rats fail to copulate despite being tested on repeated occasions with receptive females and are called non copulating (NC) rats. NC rats sniff and lick the female genitals, and show normal erectile and ejaculatory functions and hormonal levels. Sexually sluggish (S) male rats take a long t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.11.027

    authors: De Gasperín-Estrada GP,Camacho FJ,Paredes RG

    更新日期:2008-03-18 00:00:00

  • Dietary aspartame with protein on plasma and brain amino acids, brain monoamines and behavior in rats.

    abstract::Aspartame (APM; L-aspartyl-L-phenylalanine methyl ester), was investigated for its ability to alter levels of the large neutral amino acids and monoamines in overnight fasted rats allowed to consume meals with or without protein for two hours. Additionally, the possible long term behavioral consequences of APM in 25% ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90366-5

    authors: Torii K,Mimura T,Takasaki Y,Ichimura M

    更新日期:1986-01-01 00:00:00

  • Plasma lactate levels during baseline and blood pressure conditioning in the baboon.

    abstract::Lactic acid in arterial blood, systolic and diastolic blood pressures, and heart rates of baboons were examined for three naive subjects, and for five experimental subjects during baseline conditions and during training to elevate diastolic blood pressure through operant conditioning methodology. Lactic acid and cardi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90235-9

    authors: Harris AH,Turkkan JS

    更新日期:1982-10-01 00:00:00

  • Noise exposure during early development influences the acoustic startle reflex in adult rats.

    abstract::Noise exposure during the critical period of postnatal development in rats results in anomalous processing of acoustic stimuli in the adult auditory system. In the present study, the behavioral consequences of an acute acoustic trauma in the critical period are assessed in adult rats using the acoustic startle reflex ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2010.12.010

    authors: Rybalko N,Bureš Z,Burianová J,Popelář J,Grécová J,Syka J

    更新日期:2011-03-28 00:00:00

  • Effectiveness of an applied high intensity interval training as a specific operative training.

    abstract::The psychophysiological response due to stress of soldiers in actual combat operations have been determined by recent researchers, but there is a lack of knowledge about the most effective training methodologies to prepare these population for these new psychophysiological and tactical requirements. The aim of this st...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.01.009

    authors: Curiel-Regueros A,Fernández-Lucas J,Clemente-Suárez VJ

    更新日期:2019-03-15 00:00:00

  • Assessment of behavioral determinants influencing success of supervised exercise therapy in patients with intermittent claudication: A cross sectional survey.

    abstract:BACKGROUND:Supervised exercise therapy is the first step in treatment of intermittent claudication. However, adherence to supervised exercise therapy is low. Limited access and reimbursement issues are known reasons, though lack of motivation is often leading. Behavioral determinants influencing motivation and thus adh...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112732

    authors: Bolt LJJ,Jacobs MLYE,Sigterman TA,Krasznai AG,Sikkink CJJM,Schurink GWH,Bouwman LH

    更新日期:2020-03-01 00:00:00

  • Depression of rat feeding in familiar and novel environment by sulfated and nonsulfated cholecystokinin octapeptide.

    abstract::The effects of cholecystokinin octapeptide sulfate ester (CCK-8-SE) and nonsulfated cholecystokinin octapeptide (CCK-8-NS) were tested on feeding by rats in familiar and novel environment. In a familiar environment only intraperitoneally (IP) administered CCK-8-SE (0.8-24 nmole/kg) could inhibit 30 min food intake of ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90202-1

    authors: Kádár T,Penke B,Kovács K,Telegdy G

    更新日期:1985-03-01 00:00:00

  • The effect of cocaine on rotarod performance in male C57BL/6J mice.

    abstract::There is surprisingly little research examining the effect of cocaine on motor learning. Given that changes in motor activity can confound behavioral assays of learning and memory a direct assessment of cocaine on motor learning seems warranted. The present study was conducted to examine the effect of cocaine on motor...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.05.027

    authors: Heyser CJ,Vishnevetsky D,Berten S

    更新日期:2013-06-13 00:00:00

  • Scheduled feeding caused activation of dopamine metabolism in the striatum of rats.

    abstract::The effects of a time-restricted feeding schedule on dopamine (DA) release and its metabolites output in the striatum of freely moving rats were studied. Rats had access to food for only 2 h daily for 7 successive days. On the 1st or 7th day, the extracellular concentrations of DA, 3,4-dihydroxyphenylacetic acid (DOPA...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90028-e

    authors: Inoue K,Kiriike N,Okuno M,Ito H,Fujisaki Y,Matsui T,Kawakita Y

    更新日期:1993-01-01 00:00:00

  • Decreased dominance in a limited access test but normal maternal behavior in micrencephalic rats.

    abstract::Micrencephalic offspring produced by gestational treatment with the antimitotic compound/methylazoxymethanol acetate (MAM) are remarkable for substantial preservation of function concurrent with severe neural stunting. Altered behaviors in these micrencephalics, including light shyness and response perseveration, are ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)00154-b

    authors: Ferguson SA,Arrowood JW,Schultetus RS,Holson RR

    更新日期:1995-11-01 00:00:00

  • Selective hepatic vagotomy blocks pancreatic glucagon's satiety effect.

    abstract::To test the hypothesis that hepatic vagal afferents mediate the satiety effect of pancreatic glucagon, we tested the effects of selective surgical and pharmacological lesions of the abdominal vagus on glucagon's potency to inhibit feeding. Surgical disconnection of only the hepatic branch of the abdominal vagus blocke...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(83)90207-x

    authors: Geary N,Smith GP

    更新日期:1983-09-01 00:00:00

  • Chronic administration of phosphatidylserine during ontogeny enhances subject-environment interactions and radial maze performance in C57BL/6 mice.

    abstract::A longitudinal behavioral study was performed in mice exposed to the bovine brain phospholipid phosphatidylserine (BC-PS) from birth until sixty days. Examination of treated and control pups revealed no effect of the treatment on body weight nor on sensorimotor reflexes. At one and two months of age, when placed in an...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90090-q

    authors: Ammassari-Teule M,Fagioli S,Maritati M,Populin R,Pavone F

    更新日期:1990-04-01 00:00:00

  • Naloxone reversal of stress-induced suppression of LH release in the common marmoset.

    abstract::There is considerable evidence suggesting that endogenous opioid peptides (EOP) might play a role in the defensive response to stressful stimuli. The stress associated with receipt of aggression from a female conspecific and physical restraint for collection of serial blood samples (at 10-min intervals) resulted in a ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90241-2

    authors: O'Byrne KT,Lunn SF,Dixson AF

    更新日期:1989-05-01 00:00:00

  • Cadmium-induced sexual dysfunction does not involve increased hepatic metabolism of testosterone nor increased circulating levels of corticosterone.

    abstract::Sexually experienced male rats were injected IP with 0, 0.3, 1.5, 3.0, or 6.0 mg/kg cadmium chloride. The highest dose was fatal within 48 h of injection. A dose-related deficit in erectile function was observed in ex copula tests 48 h after injection. Copulatory dysfunction was evident in mating tests 72 h after inje...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90332-8

    authors: Clark JT,Jimenez B,Evans SL,Barrow R,Winfree M,Mrotek JJ

    更新日期:1994-11-01 00:00:00

  • The role of the lateral septum in anxiolysis.

    abstract::Behavior of rats in the water-lick conflict test was examined during stimulation, and after lesions of the lateral septal nucleus. Continuous low-current stimulation resulted in an anxiolytic effect, an increase in the number of licks, and hence in the number of shocks, during a signaled, punished period. This effect ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90362-j

    authors: Yadin E,Thomas E,Grishkat HL,Strickland CE

    更新日期:1993-06-01 00:00:00

  • The effect of alloxan-induced diabetes on triamine lesions in the ventromedial hypothalamus.

    abstract::It has been demonstrated that the ventromedial hypothalamus (VMH) of alloxan-induced diabetic mice is protected from subsequent gold thioglucose (GTG)-induced lesions. Another compound, 3,3'-methyliminobis-(N-methylpropylamine) (MIMPA), a triamine structurally unrelated to GTG, has been shown to cause similar VMH lesi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90227-f

    authors: Brown DF,McGuirk JP,Larsen SP,Minter SD

    更新日期:1991-01-01 00:00:00

  • Aging effects on elevated plus maze behavior in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley male and female rats.

    abstract::Male and female spontaneously hypertensive (SHR), Wistar-Kyoto (WKY), and Sprague-Dawley (SD) rats were assessed at one of two ages (postnatal day 74 or 346) for open field locomotor activity and anxiety-related behavior in the elevated plus maze (EPM). In general, the SHR displayed the least anxiety-related behavior,...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.06.009

    authors: Ferguson SA,Gray EP

    更新日期:2005-08-07 00:00:00

  • Heart rate response of the rat fetus and neonate to a chemosensory stimulus.

    abstract::Resting heart rate (HR) and HR responses of fetal and neonatal rats are described before and after intraoral infusion of isotonic saline or lemon solution. Stable measurements of resting HR were obtained for fetuses over the last three days of gestation (E19, E20, E21) and pups on the day of birth (P0) and four subseq...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90496-b

    authors: Smotherman WP,Robinson SR,Ronca AE,Alberts JR,Hepper PG

    更新日期:1991-07-01 00:00:00

  • Numerical modeling of human mastication, a simplistic view to design foods adapted to mastication abilities.

    abstract::The human diet contains a large variety of aromas, tastes and textures. The latter is particularly important since it determines whether foods are difficult to process orally and thus can be one source of food avoidance. It has also been reported in recent literature that food texture was a main driver for satiation p...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:

    authors: Le Révérend B,Hartmann C

    更新日期:2014-01-30 00:00:00

  • The effects of glucocorticoids on feeding behavior in rats.

    abstract::Glucocorticoids have major effects on food intake, however, the underlying mechanisms are poorly understood. This article highlights data on the changes that occur when glucocorticoids are removed by adrenalectomy, and the effects of central and systemic administered glucocorticoids on feeding behavior in rats. Next, ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2006.01.028

    authors: la Fleur SE

    更新日期:2006-08-30 00:00:00

  • Effects of distribution of the drug unconditioned stimulus on taste-aversion learning.

    abstract::Rats injected with lithium chloride after exposure to a taste or olfactory stimulus learn stronger aversions to these cues if the drug is administered in two small injections 35 min apart than if all of the drug is given in a single injection. This facilitation of conditioning produced by distribution of the drug unco...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(79)90203-8

    authors: Domjan M,Foster K,Gillan DJ

    更新日期:1979-11-01 00:00:00

  • The effects of long-term honey, sucrose or sugar-free diets on memory and anxiety in rats.

    abstract::Sucrose is considered by many to be detrimental to health, giving rise to deterioration of the body associated with ageing. This study was undertaken to determine whether replacing sucrose in the diet long-term with honey that has a high antioxidant content could decrease deterioration in brain function during ageing....

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.03.001

    authors: Chepulis LM,Starkey NJ,Waas JR,Molan PC

    更新日期:2009-06-22 00:00:00