Fever and the control of gram-negative bacteria.


:Although it seems obvious that fever has some important general adaptive value, it is still not clear by what means this function is manifested. One postulate is that febrile conditions result in the sequestration of soluble iron, effectively starving some pathogens of that essential nutrient. On the basis of our recent experiments, we propose a new mechanism for how fever serves to restrict a wide range of Gram-negative bacteria. The elevated temperature prevents the bacteria from synthesizing their protective LPS, thereby enabling serum complement to perforate and kill the invading pathogens even prior to the production of host antibodies.


Res Microbiol


Research in microbiology


Green MH,Vermeulen CW




Has Abstract


1994-05-01 00:00:00














  • The trehalose operon of Pseudomonas fluorescens ATCC 17400.

    abstract::The trehalose operon of Pseudomonas fluorescens ATCC 17400 consists of treP, treA and treR. The gene treP codes for a putative enzyme II subunit of the phosphotransferase system that catalyzes the phosphorylation of trehalose together with its translocation across the cell membrane and treA encodes a putative phosphot...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Matthijs S,Koedam N,Cornelis P,De Greve H

    更新日期:2000-12-01 00:00:00

  • Genetic organisation of the lipopolysaccharide O-antigen biosynthesis region of brucella melitensis 16M (wbk).

    abstract::Brucella spp. are Gram-negative, facultative intracellular bacteria that cause a zoonotic world-wide disease. As in other Gram-negative bacteria, its S-LPS (smooth lipopolysaccharide) is a major determinant of virulence. The Brucella melitensis 16M LPS O-antigen is a homopolymer of 4-formamido-4,6, dideoxymannose. In ...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Godfroid F,Cloeckaert A,Taminiau B,Danese I,Tibor A,de Bolle X,Mertens P,Letesson JJ

    更新日期:2000-10-01 00:00:00

  • Extraction, partial purification and characterization of a bacteriocin (fragicilin) produced by a strain of Bacteroides fragilis isolated from Callithrix penicillata.

    abstract::A strain of Bacteroides fragilis, isolated from the marmoset Callithrix penicillata, produced protein(s) with bacteriocin activity (fragicilin). Two active fractions (36 and 150 kDa) were isolated by chromatography. The bacteriocin exhibited iso- and heteroantagonism. It remained stable between pH 3 and 10 and at 60 d...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Farias LM,Totola AH,Miranda CM,Carvalho MA,Damasceno CA,Tavares CA,Cisalpino EO,Vieira EC

    更新日期:1994-01-01 00:00:00

  • Heavy metal resistance of some thermophiles: potential use of alpha-amylase from Anoxybacillus amylolyticus as a microbial enzymatic bioassay.

    abstract::Six thermophilic extremophiles, Anoxybacillus amylolyticus, Geobacillus thermoleovorans, Geobacillus thermoleovorans subspecies stromboliensis, Geobacillus toebii subspecies decanicus, Bacillus thermantarcticus and Thermus oshimai, isolated from different environmental sites, were studied for their heavy metal resista...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Poli A,Salerno A,Laezza G,di Donato P,Dumontet S,Nicolaus B

    更新日期:2009-03-01 00:00:00

  • Limited selection of sodium channel blocking toxin-producing bacteria from paralytic shellfish toxin-contaminated mussels (Aulacomya ater).

    abstract::Paralytic shellfish toxins (PSTs) are sodium channel blocking (SCB) toxins, produced by cyanobacteria, as well as by marine dinoflagellates and their associated bacteria, and cause serious health and economic concern worldwide. In a previous study, approximately 70% of the bacteria enriched from PST-contaminated shell...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Vásquez M,Grüttner C,Möeller B,Moore ER

    更新日期:2002-07-01 00:00:00

  • Structure/function relationships in the Escherichia coli mannitol permease: identification of regions important for membrane insertion, substrate binding and oligomerization.

    abstract::The Escherichia coli mannitol permease (EIIMtl) of the phosphoenolpyruvate-dependent phosphotransferase system is a 68-kDa membrane protein that carries out the concomitant transport and phosphorylation of D-mannitol. Previous studies indicated that there are ca. 6 membrane-spanning helices within the N-terminal half ...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Briggs CE,Khandekar SS,Jacobson GR

    更新日期:1992-02-01 00:00:00

  • The Tol-Pal proteins of the Escherichia coli cell envelope: an energized system required for outer membrane integrity?

    abstract::The outer membrane of gram-negative bacteria acts as a barrier against harmful lipophilic compounds and larger molecules unable to diffuse freely through the porins. However, outer membrane proteins together with the Tol-Pal and TonB systems have been exploited for the entry of macromolecules such as bacteriocins and ...

    journal_title:Research in microbiology

    pub_type: 杂志文章,评审


    authors: Lloubès R,Cascales E,Walburger A,Bouveret E,Lazdunski C,Bernadac A,Journet L

    更新日期:2001-07-01 00:00:00

  • Biodiversity characterization of cellulolytic bacteria present on native Chaco soil by comparison of ribosomal RNA genes.

    abstract::Sequence analysis of the 16S ribosomal RNA gene was used to study bacterial diversity of a pristine forest soil and of two cultures of the same soil enriched with cellulolytic bacteria. Our analysis revealed high bacterial diversity in the native soil sample, evidencing at least 10 phyla, in which Actinobacteria, Prot...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Talia P,Sede SM,Campos E,Rorig M,Principi D,Tosto D,Hopp HE,Grasso D,Cataldi A

    更新日期:2012-04-01 00:00:00

  • Identification of Listeria species by a semi-nested polymerase chain reaction.

    abstract::Three primers derived from the lap gene were used to distinguish Listeria monocytogenes from L.innocua and other Listeria species. L. monocytogenes and L. innocua yielded a PCR product of 600 and 300 bp, respectively, whereas a typical pattern of three amplimers was observed with L. ivanovii, L. seeligeri and L. welsh...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Manzano M,Cocolin L,Ferroni P,Gasparini V,Narduzzi D,Cantoni C,Comi G

    更新日期:1996-10-01 00:00:00

  • Fluorescence enlightens RND pump activity and the intrabacterial concentration of antibiotics.

    abstract::To understand antibiotic resistance in Gram-negative bacteria, a key point is to investigate antibiotic accumulation, which is defined by influx and efflux. Several methods exist to evaluate membrane permeability and efflux pump activity, but they present disadvantages and limitations. An optimized spectrofluorimetric...

    journal_title:Research in microbiology

    pub_type: 杂志文章,评审


    authors: Masi M,Dumont E,Vergalli J,Pajovic J,Réfrégiers M,Pagès JM

    更新日期:2018-01-01 00:00:00

  • A triclosan-ciprofloxacin cross-resistant mutant strain of Staphylococcus aureus displays an alteration in the expression of several cell membrane structural and functional genes.

    abstract::Triclosan is an antimicrobial agent found in many consumer products. Triclosan inhibits the bacterial fatty acid biosynthetic enzyme, enoyl-ACP reductase (FabI). Decreased susceptibility to triclosan correlates with ciprofloxacin resistance in several bacteria. In these bacteria, resistance to both drugs maps to genes...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Tkachenko O,Shepard J,Aris VM,Joy A,Bello A,Londono I,Marku J,Soteropoulos P,Peteroy-Kelly MA

    更新日期:2007-10-01 00:00:00

  • Biosensor for screening bacterial mercury methylation: example within the Desulfobulbaceae.

    abstract::Mercury methylation and demethylation processes govern the fate of methylmercury in aquatic ecosystems. Under anoxic conditions, methylation activity is mainly of biological origin and is often the result of sulfate-reducing bacteria. In this study, the use of a luminescent biosensor for screening methylmercury produc...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Colin Y,Gury J,Monperrus M,Gentes S,Ayala Borda P,Goni-Urriza M,Guyoneaud R

    更新日期:2018-01-01 00:00:00

  • Bacterial and H2O2 stress-induced apoptosis-like events in Cryptococcus neoformans.

    abstract::Cell death induced by adherence of Staphylococcus aureus was observed in Cryptococcus neoformans. To investigate this death mechanism, we examined three factors: actin dynamics using rhodamine-phalloidin staining, accumulation of reactive oxygen species (ROS) via conversion of 2',7'-dichlorofluorescein diacetate to 2'...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Ikeda R,Sawamura K

    更新日期:2008-11-01 00:00:00

  • Hybridization of transposon Tn501 for detection of mercury resistance sequences in a marine environment.

    abstract::Total genomic DNA isolated by concentrating seawater and mercury-resistant bacteria were hybridized with a mer probe to detect the presence of homologous DNA sequences in marine coastal waters of the Bay of Bengal, India. Coastal water extracts induced with mercury hybridized with the mer operon of transposon Tn501. M...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Prabu SK,Mahadevan A

    更新日期:1992-03-01 00:00:00

  • Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR.

    abstract::Multidrug transporters and their transcriptional regulators are key components of bacterial multidrug resistance (MDR). How these multidrug binding proteins can recognize such chemically disparate compounds represents a fascinating question from a structural standpoint and an important question in future drug developm...

    journal_title:Research in microbiology

    pub_type: 杂志文章,评审


    authors: Schumacher MA,Brennan RG

    更新日期:2003-03-01 00:00:00

  • Use of flow cytometry for analysis of phage-mediated killing of Enterobacter aerogenes.

    abstract::In this study, the use of flow cytometry to analyze phage-mediated killing of Enterobacter aerogenes under varying conditions of temperature and nutrient availability was assessed. Bacteriophage UZ1, specific for an E. aerogenes strain, was applied at a multiplicity of infection (MOI) of 1 and 1000 to a Teflon surface...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Verthé K,Verstraete W

    更新日期:2006-09-01 00:00:00

  • Phenotypic characterization of human and animal biotypes within the species Porphyromonas gingivalis.

    abstract::Ninety-nine strains of Gram-negative black-pigmented anaerobic rods, grown on Todd-Hewitt blood agar plates, were identified and characterized according to a typing scheme including UV fluorescence, catalase, trypsin-like and haemagglutinating activities, biochemical tests with the ATB 32A kit, and gas-liquid chromato...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Fournier D,Mouton C

    更新日期:1993-07-01 00:00:00

  • Regulator DegU is required for multicellular behavior in Lysinibacillus sphaericus.

    abstract::DegS and DegU make up a two component system belonging to a class of signal transduction systems that play important roles in a broad range of bacterial responses to the environment. However, little study has been done to explore the physiological functions of DegS-DegU in mosquitocidal Lysinibacillus sphaericus. In t...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Hu Y,Cai Q,Tian S,Ge Y,Yuan Z,Hu X

    更新日期:2018-04-01 00:00:00

  • Real-time PCR for characterizing the stress response of Oenococcus oeni in a wine-like medium.

    abstract::The tolerance of the lactic acid bacterium Oenococcus oeni to hostile wine conditions is essential for the success of malolactic fermentation (MLF). In this study, reverse transcription quantitative PCR (RT-qPCR) was used to quantify the transcript level of 13 genes that could play a role in adaptation of O. oeni in w...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Beltramo C,Desroche N,Tourdot-Maréchal R,Grandvalet C,Guzzo J

    更新日期:2006-04-01 00:00:00

  • Breaking free: "protein antibiotics" and phage lysis.

    abstract::Bacteriophages must destroy the bacterial cell wall to lyse their host and release their progeny into the environment. There are at least two distinct mechanisms by which phages destroy the cell wall. Bacteriophages with large genomes use a holin-endolysin system, while bacteriophages with small genomes encode a singl...

    journal_title:Research in microbiology

    pub_type: 杂志文章,评审


    authors: Bernhardt TG,Wang IN,Struck DK,Young R

    更新日期:2002-10-01 00:00:00

  • Production and consumption of methane in freshwater lake ecosystems.

    abstract::The atmospheric concentration of methane (CH(4)), a major greenhouse gas, is mainly controlled by the activities of methane-producing (methanogens) and methane-consuming (methanotrophs) microorganisms. Freshwater lakes are identified as one of the main CH(4) sources, as it was estimated that they contribute to 6-16% o...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Borrel G,Jézéquel D,Biderre-Petit C,Morel-Desrosiers N,Morel JP,Peyret P,Fonty G,Lehours AC

    更新日期:2011-11-01 00:00:00

  • Cra and the control of carbon flux via metabolic pathways.

    abstract::The catabolite repressor-activator (Cra) protein controls the direction of carbon flux through metabolic pathways in enteric bacteria. Cra binds to the control regions of target genes and exerts a negative effect on the expression of genes encoding glycolytic and Entner-Doudoroff enzymes, while exerting a positive eff...

    journal_title:Research in microbiology

    pub_type: 杂志文章,评审


    authors: Ramseier TM

    更新日期:1996-07-01 00:00:00

  • Eubacterial diversity of activated biomass from a common effluent treatment plant.

    abstract::A common effluent treatment plant (CETP) is a biological wastewater treatment facility that receives wastewater from different industries. The activated biomass in the CETP survives on a wide range of chemicals with no fixed wastewater characteristics. We carried out a diversity analysis of this activated biomass usin...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Kapley A,De Baere T,Purohit HJ

    更新日期:2007-07-01 00:00:00

  • CreA modulates the XlnR-induced expression on xylose of Aspergillus niger genes involved in xylan degradation.

    abstract::The expression of the feruloyl esterase gene faeA, the alpha-glucuronidase gene aguA, the endoxylanase gene xlnB, and the beta-xylosidase gene xlnD from Aspergillus niger on xylose was studied in a wild-type strain and in a CreA mutant. A decrease in expression of all four genes was observed with increasing xylose con...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: de Vries RP,Visser J,de Graaff LH

    更新日期:1999-05-01 00:00:00

  • Relationship of chemical structures of textile dyes on the pre-adaptation medium and the potentialities of their biodegradation by Phanerochaete chrysosporium.

    abstract::Azo dye derivatives of azobenzene constitute the largest group of dyes used in the textile industry and possess recalcitrant chemical groups, such as those of azo and sulphonic acid. Some microorganisms are able to degrade these aromatic compounds. In the present work, decolourisation of culture media containing azo d...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Martins MA,Queiroz MJ,Silvestre AJ,Lima N

    更新日期:2002-07-01 00:00:00

  • Bacterial leaf symbiosis in Ardisia (Myrsinoideae, Primulaceae): molecular evidence for host specificity.

    abstract::The association between bacteria and leaves in Ardisia has been described as a cyclic and obligate symbiosis in which bacteria are maintained throughout all stages of the plant's life cycle to guarantee normal growth and survival of the host. This intimate interaction suggests that both partners have co-diversified to...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Lemaire B,Smets E,Dessein S

    更新日期:2011-06-01 00:00:00

  • Characterization and phylogenetic identification of a species of spherical multicellular magnetotactic prokaryotes that produces both magnetite and greigite crystals.

    abstract::Magnetotactic bacteria (MTB) are a group of Gram-negative bacteria synthesizing magnetic crystals that allow them aligning along magnetic field lines. They have diverse morphologies including cocci, rods, vibrio, spirilla, and multicellular magnetotactic prokaryotes (MMPs). MMPs are composed of 10-57 cells with peritr...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Zhang R,Chen YR,Du HJ,Zhang WY,Pan HM,Xiao T,Wu LF

    更新日期:2014-09-01 00:00:00

  • Methionine biosynthesis in Agrobacterium tumefaciens: study of the first enzyme.

    abstract::Here we characterize the first step in methionine biosynthesis in Agrobacterium tumefaciens, an α-proteobacterium. We explored the metA gene and its products and found several unique properties. Although the gene was annotated as a homoserine transsuccinylase, based upon sequence similarity to characterized homologs i...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Rotem O,Biran D,Ron EZ

    更新日期:2013-01-01 00:00:00

  • Surface migration of Staphylococcus xylosus on low-agar media.

    abstract::Staphylococcus xylosus is a commensal species commonly found on the skin of mammals, but also currently used as starter culture for meat fermentation. Most strains of this species colonize by forming a biofilm on abiotic surfaces. We show here that the majority of S. xylosus strains also exhibit extensive colony sprea...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Dordet-Frisoni E,Gaillard-Martinie B,Talon R,Leroy S

    更新日期:2008-05-01 00:00:00

  • Evolution of mollicutes: down a bumpy road with twists and turns.

    abstract::Mollicute evolution has been marked by significant changes in genome structure and use of their genetic information. These include a reduction in their genome G+C content and the use by most mollicutes of the UGA universal stop codon as tryptophan. More striking is the size reduction in their genome which, for some sp...

    journal_title:Research in microbiology

    pub_type: 杂志文章


    authors: Sirand-Pugnet P,Citti C,Barré A,Blanchard A

    更新日期:2007-12-01 00:00:00