ECF-type ABC transporters for uptake of vitamins and transition metal ions into prokaryotic cells.

Abstract:

:Energy-coupling factor (ECF) transporters mediate the uptake of micronutrients in prokaryotes. They consist of two ATP-binding-cassette family ATPases, a transmembrane coupling protein (T component) and a substrate-binding membrane protein (S component). ECF transporters for Co2+ and Ni2+ ions have one or two additional proteins with extracytoplasmic regions but poorly understood function. Homologs of T components with a predicted localization in plastids are widespread in plants but their physiological role is unclear. S components in eukaryotes are very rare and restricted to biotin-specific variants. Apart from a potential contribution to the export of flavins to serve the assembly of extracytoplasmic electron transfer chains, ECF transporters function as importers.

journal_name

Res Microbiol

journal_title

Research in microbiology

authors

Finkenwirth F,Eitinger T

doi

10.1016/j.resmic.2019.06.007

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

358-365

issue

8

eissn

0923-2508

issn

1769-7123

pii

S0923-2508(19)30064-6

journal_volume

170

pub_type

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