Abstract:
:The authors retrospectively reviewed the efficacy of mycophenolate mofetil (MMF; mean dose, 2 g/day given for an average of 14 months) in 21 patients with immune demyelinating polyneuropathy. There were no significant differences in the median strength, sensory, or Rankin scores before and after treatment. In patients with immunoglobulin (Ig) M neuropathy, the M-protein decreased by 22%. Three patients with chronic inflammatory demyelinating polyneuropathy (30%) and one patient with IgM neuropathy (13%) improved. The authors found that MMF induced a modest benefit in ~20% of their patients and stabilized patient condition, allowing reduction of steroid or IVIg therapy.
journal_name
Neurologyjournal_title
Neurologyauthors
Gorson KC,Amato AA,Ropper AHdoi
10.1212/01.wnl.0000134676.05850.c0subject
Has Abstractpub_date
2004-08-24 00:00:00pages
715-7issue
4eissn
0028-3878issn
1526-632Xpii
63/4/715journal_volume
63pub_type
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