Abstract:
BACKGROUND:Most cavernous sinus dural arteriovenous malformations (CSdAVM) have a benign clinical course. Those CSdAVM that drain into cortical veins have an increased risk for neurologic complications. OBJECTIVE:To find whether a specific clinical sign predicts cortical venous drainage (CVD) in CSdAVM. METHODS:The records of 118 patients with CSdAVM were evaluated for the clinical features of the disorder and tested for predictive value of CVD demonstrated angiographically or suggested by MRI using logistic regression and odds ratio (OR) analysis. RESULTS:Clinical signs that predicted the presence of CVD included bilateral orbital signs (p = 0.004, OR = 23.84) and presence of a postauricular bruit (p = 0.035, OR = 23.8). No other clinical sign predicted the presence of CVD, including extraocular muscle dysfunction, abducens or oculomotor dysfunction, increased intraocular pressure, venous stasis retinopathy, choroidal effusion, optic neuropathy, subjective bruit, and objective orbital bruit. CONCLUSION:Patients who present with or develop bilateral orbital congestion should be recognized as being at increased risk for CVD.
journal_name
Neurologyjournal_title
Neurologyauthors
Stiebel-Kalish H,Setton A,Berenstein A,Kalish Y,Nimii Y,Kupersmith MJdoi
10.1212/wnl.58.10.1521subject
Has Abstractpub_date
2002-05-28 00:00:00pages
1521-4issue
10eissn
0028-3878issn
1526-632Xjournal_volume
58pub_type
杂志文章,评审相关文献
NEUROLOGY文献大全abstract:BACKGROUND:Neutralizing antibodies (NAB) to interferon beta (IFNbeta) occur in about one-third of MS patients treated with IFNbeta-1b and there is an association with a loss of clinical and MRI efficacy. However, there are no data regarding the bioavailability of IFNbeta-1b in patients with and without NAB. METHODS:Th...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.52.6.1239
更新日期:1999-04-12 00:00:00
abstract::About one-third of patients with acoustic tumor (AT) initially seek medical attention for nonaudiologic complaints. The nonspecific early symptoms of AT require the inclusion of AT in many neurologic differential diagnoses. Advances in electrophysiologic and radiographic tests have allowed earlier diagnosis of AT at a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.33.2.211
更新日期:1983-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the predictive utility of self-reported and informant-reported functional deficits in patients with mild cognitive impairment (MCI) for the follow-up diagnosis of probable AD. METHODS:The Pfeffer Functional Activities Questionnaire (FAQ) and Lawton Instrumental Activities of Daily Living (IADL) S...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.58.5.758
更新日期:2002-03-12 00:00:00
abstract::A patient who abused multiple drugs developed a rapidly progressive mononeuropathy multiplex, which appeared to respond to corticosteroid therapy with partial resolution. Intravenous methamphetamine had been used almost exclusively from the fourth month prior to the onset of symptoms. Biopsy material revealed a necrot...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.25.6.570
更新日期:1975-06-01 00:00:00
abstract::Using transcranial Doppler (TCD) ultrasonography in patients with high-grade (> or = 70%) internal carotid artery (ICA) stenosis, we examined the relation between the rate of TCD-detected silent microembolism of the ipsilateral middle cerebral artery and a history of recent (< 121 days) ischemic symptoms attributable ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.4.615
更新日期:1994-04-01 00:00:00
abstract::We prospectively evaluated 84 consecutive adult patients with chronic liver disease before and after liver transplantation to define the type and frequency of post-transplant neurologic complications, and to assess possible pretransplant and operative variables associated with in-hospital CNS complications. There were...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.7.1226
更新日期:1994-07-01 00:00:00
abstract::We studied five patients with nonhemorrhagic thalamic infarction with neuropsychological tests, CT, and somatosensory evoked responses (SERs). The three patients with left thalamic lesions had abnormalities of language, memory, visuospatial processing, intellect, and personality-changes compatible with dementia. The t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.34.1.14
更新日期:1984-01-01 00:00:00
abstract::The effects of lysine vasopressin on memory and cognitive deficits in Alzheimer disease was investigated. In a double-blind study, seven patients were given 16 units of lysine vasopressin per day for 10 days and were compared with seven different patients receiving placebo. No significant difference in performance bet...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.32.6.674
更新日期:1982-06-01 00:00:00
abstract:OBJECTIVE:To investigate the added value of hippocampal atrophy rates over whole brain volume measurements on MRI in patients with Alzheimer disease (AD), patients with mild cognitive impairment (MCI), and controls. METHODS:We included 64 patients with AD (67 +/- 9 years; F/M 38/26), 44 patients with MCI (71 +/- 6 yea...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000344568.09360.31
更新日期:2009-03-17 00:00:00
abstract::We identified seven patients with refractory partial epilepsy and sleep apnea. Treatment of the sleep apnea with nasal continuous positive airway pressure (CPAP), protriptyline, trazodone, acetazolamide, or tracheostomy reduced seizure frequency and severity in six patients. Success with CPAP depended largely on compl...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.11.2060
更新日期:1994-11-01 00:00:00
abstract::Placebo, or sham surgery, as a control condition in surgical clinical trials in Parkinson disease (PD) remains controversial. The authors reviewed the adverse effects reported in double blind, placebo surgery controlled trials for PD. Placebo surgeries were generally safe and well tolerated but the number of subjects ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000171957.90640.b5
更新日期:2005-10-11 00:00:00
abstract::Juvenile myoclonic epilepsy (JME) is a distinct subform of idiopathic generalized epilepsy of adolescence. Linkage studies with Bf and serologic HLA markers in families of JME patients have shown a tight linkage on chromosome 6. We present a linkage analysis with HLA-DQ restriction fragment length polymorphisms on mor...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.41.10.1651
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:To determine the prognostic role of late auditory (N100) and cognitive evoked potentials (MMN) for awakening in a cohort of comatose patients categorized by etiology. METHODS:The authors prospectively studied a series of 346 comatose patients. Coma was caused by stroke (n = 125), trauma (n = 96), anoxia (n ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000134670.10384.e2
更新日期:2004-08-24 00:00:00
abstract:OBJECTIVE:To investigate possible correlations between tumor location and genetic alterations in a series of oligodendrogliomas. METHODS:A series of 158 consecutive oligodendrogliomas were retrospectively reviewed. In each case, the radiologic picture and the chromosome 1p (chr 1p) status of the tumor detected by the ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000148642.26985.68
更新日期:2004-12-28 00:00:00
abstract:OBJECTIVE:There is controversy about the clinical consequences of intermediate alleles (IAs) in Huntington disease (HD). The main objective of this study was to establish the clinical manifestations of IA carriers for a prospective, international, European HD registry. METHODS:We assessed a cohort of participants at r...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002944
更新日期:2016-08-09 00:00:00
abstract:OBJECTIVE:To develop evidence-based recommendations for complementary and alternative medicine (CAM) in multiple sclerosis (MS). METHODS:We searched the literature (1970-March 2011; March 2011-September 2013 MEDLINE search), classified articles, and linked recommendations to evidence. RESULTS AND RECOMMENDATIONS:Clin...
journal_title:Neurology
pub_type: 杂志文章,meta分析
doi:10.1212/WNL.0000000000000250
更新日期:2014-03-25 00:00:00
abstract:OBJECTIVE:To analyze the associations between cardiovascular fitness at age 18 years and future risk of epilepsy. METHODS:Population-based cohort study of Swedish male conscripts (n = 1,173,079) born in 1950-1987, who were followed for up to 40 years. Data on cardiovascular fitness were collected during conscription e...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3182a4a4c0
更新日期:2013-09-17 00:00:00
abstract:BACKGROUND:Although the APOE epsilon 4 allele increases the risk of developing AD, the effects of the epsilon 4 allele on brain atrophy in clinical AD patients are controversial. OBJECTIVE:To investigate a possible relationship between the genetic variants of APOE and brain atrophy in patients with AD. METHODS:Using ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.8.1461
更新日期:2001-10-23 00:00:00
abstract::An 18-year-old man had noticed increasing difficulty in walking for 4 years. Examination disclosed spastic paraparesis and posterior column signs suggestive of subacute combined degeneration of the spinal cord. Urinalysis, urinary thin-layer chromatography, and intestinal biopsy disclosed typical cystinuria. Perniciou...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.25.10.994
更新日期:1975-10-01 00:00:00
abstract:OBJECTIVES:While plasma biomarkers have been proposed to aid in the clinical diagnosis of Alzheimer disease (AD), few biomarkers have been validated in independent patient cohorts. Here we aim to determine plasma biomarkers associated with AD in 2 independent cohorts and validate the findings in the multicenter Alzheim...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0b013e318266fa70
更新日期:2012-08-28 00:00:00
abstract:OBJECTIVE:To assess pathologic changes in prospectively characterized subjects with essential tremor (ET). METHODS:Subjects enrolled in the Sun Health Research Institute Brain and Body Donation Program were examined annually by a movement disorders neurologist, and semiannually by a behavioral neurologist and neuropsy...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000310425.76205.02
更新日期:2008-04-15 00:00:00
abstract::Human cytomegalovirus and herpes simplex virus DNA probes were labeled in vitro and hybridized to the DNA extracted from brains of patients with multiple sclerosis (MS) to detect the presence of genetic information related to these viruses. We were unable to detect any virus-related genetic information complementary t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.5.530
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To determine whether blood-based biomarkers can differentiate older veterans with and without traumatic brain injury (TBI) and cognitive impairment (CogI). METHODS:We enrolled 155 veterans from 2 veterans' retirement homes: 90 without TBI and 65 with TBI history. Participants were further separated into CogI...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000010087
更新日期:2020-09-01 00:00:00
abstract::Eighteen patients with congenital nystagmus were studied with the techniques of electronystagmography and computer analysis. We found several complex wave forms of congenital nystagmus in the primary position of gaze above those of jerk and pendular nystagmus as defined clinically. An etiologic classification of motor...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.4.326
更新日期:1976-04-01 00:00:00
abstract:OBJECTIVE:To assess the medial plantar nerve action potential (NAP) and skin biopsy in the evaluation of suspected distal sensory neuropathies (SN) with normal routine nerve conduction studies (NCS). METHODS:A total of 110 consecutive patients with suspected distal SN and normal routine NCS underwent medial plantar NA...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000137036.26601.84
更新日期:2004-09-14 00:00:00
abstract::Symptoms in patients with demyelinating disorders are associated with 3 important conduction abnormalities: complete conduction block, rate-dependent conduction block, and slowed impulse conduction. The recent observation that the electrogenic Na/K pump causes the nerve membrane hyperpolarization responsible for rate-...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.39.10.1364
更新日期:1989-10-01 00:00:00
abstract::Four patients with disabling action tremor in the setting of MS were treated with isoniazid (800 to 1200 mg per day). All patients showed significant improvement of the tremor, allowing more functional use of their extremities. To the best of our knowledge, this is the only medical treatment for this type of tremor. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.32.8.912
更新日期:1982-08-01 00:00:00
abstract:OBJECTIVE:To study the presenting features and value of routine diagnostic procedures in patients with leptomeningeal metastases (LMM) related to the primary malignancy to improve diagnostic assessment. METHODS:The authors studied the presenting features and value of routine diagnostic procedures in relation to the hi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.2.382
更新日期:1999-07-22 00:00:00
abstract:OBJECTIVE:We aimed to perform an observational study of age at loss of independent ambulation (LoA) and side-effect profiles associated with different glucocorticoid corticosteroid (GC) regimens in Duchenne muscular dystrophy (DMD). METHODS:We studied 340 participants in the Cooperative International Neuromuscular Res...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001950
更新日期:2015-09-22 00:00:00
abstract:BACKGROUND:Recent studies demonstrated an excess of winter births in children with brain tumors and in adults with various neurologic or psychiatric diseases relative to the general population. OBJECTIVE:To investigate a possible association between month of birth and risk of brain tumors in adults using data from a l...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/01.wnl.0000129984.01327.9d
更新日期:2004-07-27 00:00:00