Treatment of action tremor in multiple sclerosis with isoniazid.

Abstract:

:Four patients with disabling action tremor in the setting of MS were treated with isoniazid (800 to 1200 mg per day). All patients showed significant improvement of the tremor, allowing more functional use of their extremities. To the best of our knowledge, this is the only medical treatment for this type of tremor.

journal_name

Neurology

journal_title

Neurology

authors

Sabra AF,Hallett M,Sudarsky L,Mullally W

doi

10.1212/wnl.32.8.912

subject

Has Abstract

pub_date

1982-08-01 00:00:00

pages

912-3

issue

8

eissn

0028-3878

issn

1526-632X

journal_volume

32

pub_type

杂志文章
  • Melioidosis and bilateral third-nerve palsies.

    abstract::Central nervous system involvement in melioidosis is unusual. We describe a 34-year-old man who developed a Pseudomonas pseudomallei meningitis, manifested as bilateral third-nerve palsies, 13 years after having been in southeast Asia. Diagnosis was established by a fourfold rise in the serum antibody titer for the ba...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.1.105

    authors: Beck RW,Janssen RS,Smiley ML,Schatz NJ,Savino PJ,Rubin DH

    更新日期:1984-01-01 00:00:00

  • Effect of rebleeding on the course and incidence of vasospasm after subarachnoid hemorrhage.

    abstract:OBJECTIVE:Rebleeding of an aneurysm is a leading cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Whereas numerous studies have demonstrated the risk factors associated with rebleeding, few data on complications of rebleeding, including its effect on the development of delayed cerebral ischemia (DC...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31823ed0a4

    authors: Lord AS,Fernandez L,Schmidt JM,Mayer SA,Claassen J,Lee K,Connolly ES,Badjatia N

    更新日期:2012-01-03 00:00:00

  • Normal pressure hydrocephalus, parkinsonism, and primary empty sella--coincidence or cause-effect?

    abstract::The triad of normal-pressure hydrocephalus, parkinsonism, and primary empty sella appeared in a 70-year-old woman. There was dramatic resolution of the extrapyramidal signs and symptoms on treatment with levodopa-carbidopa and ventriculojugular shunt. The syndrome may be the result of several mechanisms, but an altera...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.11.1191

    authors: Spagna VA,Maeder MC,Johnson JC,Mazzaferri EL

    更新日期:1978-11-01 00:00:00

  • Leukoencephalopathy induced by levamisole alone for the treatment of recurrent aphthous ulcers.

    abstract::We report imaging and clinical findings of leukoencephalopathy occurring after levamisole. The lesions were hypoattenuating on CT and appeared as multifocal oval or elliptical foci in the white matter or along the subependymal veins on MRI. Most lesions resolve after prompt withdrawal of levamisole. Detailed history t...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000237344.06122.79

    authors: Liu HM,Hsieh WJ,Yang CC,Wu VC,Wu KD

    更新日期:2006-09-26 00:00:00

  • Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society.

    abstract:OBJECTIVE:To provide updated evidence-based recommendations for migraine prevention using pharmacologic treatment with or without cognitive behavioral therapy in the pediatric population. METHODS:The authors systematically reviewed literature from January 2003 to August 2017 and developed practice recommendations usin...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/WNL.0000000000008105

    authors: Oskoui M,Pringsheim T,Billinghurst L,Potrebic S,Gersz EM,Gloss D,Holler-Managan Y,Leininger E,Licking N,Mack K,Powers SW,Sowell M,Victorio MC,Yonker M,Zanitsch H,Hershey AD

    更新日期:2019-09-10 00:00:00

  • The clinical-DWI mismatch: a new diagnostic approach to the brain tissue at risk of infarction.

    abstract:OBJECTIVE:To evaluate the usefulness of a mismatch between the severity of acute clinical manifestations and the diffusion-weighted imaging (DWI) lesion in predicting early stroke outcome and infarct volume. METHODS:One hundred sixty-six patients with a hemispheric ischemic stroke of <12 hours' duration were studied. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000130570.41127.ea

    authors: Dávalos A,Blanco M,Pedraza S,Leira R,Castellanos M,Pumar JM,Silva Y,Serena J,Castillo J

    更新日期:2004-06-22 00:00:00

  • Prevalence of headaches in a Chinese elderly population in Kinmen: age and gender effect and cross-cultural comparisons.

    abstract:OBJECTIVE:To investigate the prevalence of headaches in a Chinese elderly population. BACKGROUND:There are few headache surveys in the elderly. Previous studies have shown a low headache prevalence in Chinese. METHODS: TARGET POPULATION:eligible registered residents > or = 65 years old (N = 2,003) in two townships o...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.49.1.195

    authors: Wang SJ,Liu HC,Fuh JL,Liu CY,Lin KP,Chen HM,Lin CH,Wang PN,Hsu LC,Wang HC,Lin KN

    更新日期:1997-07-01 00:00:00

  • Absence of cystatin C mutation in sporadic cerebral amyloid angiopathy-related hemorrhage.

    abstract::In Icelandic pedigrees a cystatin C mutation, glutamine 68 (L68Q), causes autosomal dominant cerebral amyloid angiopathy-related hemorrhage (CAAH). We examined 33 patients with sporadic CAAH for this mutation. None carried L68Q and, including this report, only one of 52 published cases of sporadic CAAH has had the cys...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.1.242

    authors: McCarron MO,Nicoll JA,Stewart J,Ironside JW,Mann DM,Love S,Graham DI,Grubb A

    更新日期:2000-01-11 00:00:00

  • Association of APOE polymorphisms with disease severity in MS is limited to women.

    abstract::The authors studied the association of an exon 4 (E4*epsilon2/3/4) and three promoter polymorphisms of APOE with disease course and severity stratified by gender in 221 patients with multiple sclerosis from two overlapping population-based prevalence cohorts. Women carriers of the E4*epsilon2 allele took longer to att...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000113721.83287.83

    authors: Kantarci OH,Hebrink DD,Achenbach SJ,Pittock SJ,Altintas A,Schaefer-Klein JL,Atkinson EJ,De Andrade M,McMurray CT,Rodriguez M,Weinshenker BG

    更新日期:2004-03-09 00:00:00

  • Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies.

    abstract:OBJECTIVE:To assess the importance of MAPT variant p.A152T in the risk of synucleinopathies. METHODS:In this case-control study, we screened a large global series of patients and controls, and assessed associations between p.A152T and disease risk. We included 3,229 patients with clinical Parkinson disease (PD), 442 w...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000001946

    authors: Labbé C,Ogaki K,Lorenzo-Betancor O,Soto-Ortolaza AI,Walton RL,Rayaprolu S,Fujioka S,Murray ME,Heckman MG,Puschmann A,McCarthy A,Lynch T,Siuda J,Opala G,Rudzinska M,Krygowska-Wajs A,Barcikowska M,Czyzewski K,Sanotsky Y

    更新日期:2015-11-10 00:00:00

  • Clinical characteristics of transient ischemic attacks in black patients.

    abstract::We analyzed the clinical, CT, and angiographic findings in 50 black patients with carotid transient ischemic attacks (TIAs). Thirty-two percent had TIAs lasting less than 1 hour, 26% had TIAs lasting 1 to 6 hours, and 42% had TIAs lasting 6 to 24 hours. Fifty-two percent of TIA patients had CT evidence of cerebral inf...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.9.1410

    authors: Weisberg LA

    更新日期:1991-09-01 00:00:00

  • A randomized controlled study of pergolide in patients with restless legs syndrome.

    abstract:BACKGROUND:Open clinical trials indicate that low doses of pergolide, a long-acting D1 and D2 dopamine agonist, lead to a reduction in the symptoms of restless legs syndrome (RLS) with subjective improvement in sleep quality. OBJECTIVE:To assess the therapeutic efficacy of pergolide in improving sleep and subjective m...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1212/wnl.52.5.944

    authors: Wetter TC,Stiasny K,Winkelmann J,Buhlinger A,Brandenburg U,Penzel T,Medori R,Rubin M,Oertel WH,Trenkwalder C

    更新日期:1999-03-23 00:00:00

  • Long-term interferon beta-1b therapy for MS: is routine thyroid assessment always useful?

    abstract:BACKGROUND:The authors previously reported on the development of thyroid dysfunction and autoimmunity during 1-year treatment of patients with MS with interferon-beta 1b (IFN beta-1b). OBJECTIVE:To evaluate the evolution of incident thyroid disease and the possible development of more thyroid disease during longer ter...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章

    doi:10.1212/wnl.55.4.549

    authors: Monzani F,Caraccio N,Casolaro A,Lombardo F,Moscato G,Murri L,Ferrannini E,Meucci G

    更新日期:2000-08-22 00:00:00

  • Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment.

    abstract:OBJECTIVE:Recent studies have suggested modifications of serotonin cerebral metabolism and of 5-HT(1A) receptors density in Alzheimer disease (AD). This study aims at exploring hippocampus 5-HT(1A) receptor density in patients at the amnesic mild cognitive impairment (aMCI) and mild AD dementia stages. METHODS:With us...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000271377.52421.4a

    authors: Truchot L,Costes SN,Zimmer L,Laurent B,Le Bars D,Thomas-Antérion C,Croisile B,Mercier B,Hermier M,Vighetto A,Krolak-Salmon P

    更新日期:2007-09-04 00:00:00

  • Current treatment pathways in ALS: a European perspective.

    abstract::This article presents the findings relating to the European subgroup of 91 patients in an international survey of the current diagnosis and treatment of patients with amyotrophic lateral sclerosis (ALS). The mean time between first symptoms and first consultation with a physician was 4.9 months, and mean delay in seei...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:

    authors: Dengler R

    更新日期:1999-01-01 00:00:00

  • Early hormonal changes during valproate or carbamazepine treatment: a 3-month study.

    abstract:BACKGROUND:Long-term treatment with valproate (VPA) or carbamazepine (CBZ) may induce reproductive endocrine disorders in patients with epilepsy. METHODS:Serum concentrations of reproductive hormones were studied in 17 women and 22 men with recently diagnosed epilepsy before they started either VPA or CBZ medication, ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.3.440

    authors: Rättyä J,Pakarinen AJ,Knip M,Repo-Outakoski M,Myllylä VV,Isojärvi JI

    更新日期:2001-08-14 00:00:00

  • False localizing sign of cervico-thoracic CSF leak in spontaneous intracranial hypotension.

    abstract:OBJECTIVE:Spontaneous spinal CSF leaks are an important cause of new-onset headaches. Such leaks are reported to be particularly common at the cervico-thoracic junction. The authors undertook a study to determine the significance of these cervico-thoracic CSF leaks. METHODS:The patient population consisted of a consec...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000001697

    authors: Schievink WI,Maya MM,Chu RM,Moser FG

    更新日期:2015-06-16 00:00:00

  • Spinal muscular atrophy is not the result of mutations at the beta-hexosaminidase or GM2-activator locus.

    abstract::The disease locus for the clinically heterogeneous childhood spinal muscular atrophies (SMA) maps to the chromosome 5 subregion, 5q11.2-13.3. The beta-subunit of beta-D-N-acetylhexosaminidase (hexosaminidase) (EC 3.2.1.52) (Hex B) maps to the same region, and the protein required for substrate recognition by this enzy...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.9.1418

    authors: Kleyn PW,Brzustowicz LM,Wilhelmsen KC,Freimer NB,Miller JM,Munsat TL,Gilliam TC

    更新日期:1991-09-01 00:00:00

  • Multiple sclerosis and age at exposure to childhood diseases and animals: cases and their friends.

    abstract::Eighty-eight multiple sclerosis case-friend pairs were interviewed by telephone to elicit information about early-life exposures. Available mothers were also interviewed. Risk factors included childhood diseases, exposures to animals, and residence. We found a positive association between MS and having measles at a la...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.9.1144

    authors: Sullivan CB,Visscher BR,Detels R

    更新日期:1984-09-01 00:00:00

  • Cardiac injury associated with neurogenic pulmonary edema following subarachnoid hemorrhage.

    abstract:OBJECTIVE:To describe the clinical features of cardiac injury associated with neurogenic pulmonary edema (NPE) in patients with acute subarachnoid hemorrhage (SAH). BACKGROUND:NPE is generally viewed as a form of noncardiogenic pulmonary edema related to massive sympathetic discharge. METHODS:Case series. RESULTS:We...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.44.5.815

    authors: Mayer SA,Fink ME,Homma S,Sherman D,LiMandri G,Lennihan L,Solomon RA,Klebanoff LM,Beckford A,Raps EC

    更新日期:1994-05-01 00:00:00

  • The impact of new pharmaceutical agents on the cost of neurologic care.

    abstract::Since the emergence of the specialty, neurologists have worked with a rather restricted list of relatively inexpensive pharmacologic agents. This is rapidly changing with the development of new agents for the treatment of migraine, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and epilepsy, accelerated...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.45.3.569

    authors: Gunderson CH

    更新日期:1995-03-01 00:00:00

  • Recanalization after thrombolysis in stroke patients: predictors and prognostic implications.

    abstract:OBJECTIVE:To estimate rates, predictors, and prognostic importance of recanalization in an unselected series of patients with stroke treated with IV thrombolysis. METHODS:We performed a CT angiography or transcranial Doppler (TCD) follow-up examination 24 hours after IV thrombolysis in 64 patients with documented occl...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000250341.38014.d2

    authors: Zangerle A,Kiechl S,Spiegel M,Furtner M,Knoflach M,Werner P,Mair A,Wille G,Schmidauer C,Gautsch K,Gotwald T,Felber S,Poewe W,Willeit J

    更新日期:2007-01-02 00:00:00

  • Reasons for exclusion from thrombolytic therapy following acute ischemic stroke.

    abstract::Despite evidence for the efficacy of thrombolytic therapy in acute ischemic stroke, only 1 to 7% of patients receive this therapy. The authors sought to determine the reasons for exclusion from tissue plasminogen activator (tPA) in an acute setting and found avoidable causes in 18% of patients. Improvements in intraho...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000152041.20486.2F

    authors: Cocho D,Belvís R,Martí-Fàbregas J,Molina-Porcel L,Díaz-Manera J,Aleu A,Pagonabarraga J,García-Bargo D,Mauri A,Martí-Vilalta JL

    更新日期:2005-02-22 00:00:00

  • Naming vs knowing faces in primary progressive aphasia: a tale of 2 hemispheres.

    abstract:OBJECTIVES:This study examines the anatomical correlates of naming vs recognizing faces using a novel measure that utilizes culturally relevant and age-appropriate items, the Northwestern University Famous Faces (NUFFACE) Test, in primary progressive aphasia (PPA), a syndrome characterized by progressive language defic...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3182a08f83

    authors: Gefen T,Wieneke C,Martersteck A,Whitney K,Weintraub S,Mesulam MM,Rogalski E

    更新日期:2013-08-13 00:00:00

  • Neural transplantation in Huntington disease: long-term grafts in two patients.

    abstract:OBJECTIVE:Clinical trials of fetal neural tissue transplantation for Huntington disease (HD) have been conducted with variable clinical results. However, no long-term analysis of graft survival and integration has been published. Here, we report the pathologic findings in two patients with HD who died 74 and 79 months ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000264504.14301.f5

    authors: Keene CD,Sonnen JA,Swanson PD,Kopyov O,Leverenz JB,Bird TD,Montine TJ

    更新日期:2007-06-12 00:00:00

  • Neuropathy in Parkinson disease: prevalence and determinants.

    abstract:OBJECTIVE:To ascertain the prevalence and determinants of neuropathy in patients with Parkinson disease (PD), in particular, the roles of vitamin B12 and levodopa exposure. METHODS:We performed a cross-sectional study of 37 patients with PD and 37 age- and gender-matched controls, using a sensitive and validated neuro...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31823a0ee4

    authors: Rajabally YA,Martey J

    更新日期:2011-11-29 00:00:00

  • History of multiple sclerosis in 2 successive pregnancies: A French and Italian cohort.

    abstract:OBJECTIVE:To evaluate the risk of relapses during pregnancy and in the first 3 months after delivery in 2 successive pregnancies in a cohort of French and Italian women with multiple sclerosis (MS). METHODS:A total of 93 women were included if they had had 2 pregnancies followed prospectively after MS onset between Ja...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000003036

    authors: Benoit A,Durand-Dubief F,Amato MP,Portaccio E,Casey R,Roggerone S,Androdias G,Gignoux L,Ionescu I,Marrosu MG,Cocco E,Ghezzi A,Annovazzi P,Trojano M,Simone M,Marignier R,Confavreux C,Vukusic S

    更新日期:2016-09-27 00:00:00

  • Thrombectomy vs medical management in low NIHSS acute anterior circulation stroke.

    abstract:OBJECTIVE:To undertake an effectiveness and safety analysis of EVT in patients with LVO and NIH Stroke Scale (NIHSS) score ≤6 using datasets of multicenter and multinational nature. METHODS:We pooled patients with anterior circulation occlusion from 3 prospective international cohorts. Patients were eligible if presen...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000010955

    authors: Volny O,Zerna C,Tomek A,Bar M,Rocek M,Padr R,Cihlar F,Nevsimalova M,Jurak L,Havlicek R,Kovar M,Sevcik P,Rohan V,Fiksa J,Cernik D,Jura R,Vaclavik D,Cimflova P,Puig J,Dowlatshahi D,Khaw AV,Fainardi E,Najm M,De

    更新日期:2020-12-15 00:00:00

  • Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy.

    abstract::Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke. Conversely, the systemic effects of a wide variety of critical illnesses can lead to CNS dysfunction, which can precipitate respiratory failure. Reported is a patient in whom an acute encephalop...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000064166.82077.eb

    authors: Dyken ME,Yamada T,Berger HA

    更新日期:2003-05-27 00:00:00

  • Estimating cerebral microinfarct burden from autopsy samples.

    abstract:OBJECTIVE:To estimate whole-brain microinfarct burden from microinfarct counts in routine postmortem examination. METHODS:We developed a simple mathematical method to estimate the total number of cerebral microinfarcts from counts obtained in the small amount of tissue routinely examined in brain autopsies. We derived...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31828c2f52

    authors: Westover MB,Bianchi MT,Yang C,Schneider JA,Greenberg SM

    更新日期:2013-04-09 00:00:00