Summary of evidence-based guideline: complementary and alternative medicine in multiple sclerosis: report of the guideline development subcommittee of the American Academy of Neurology.

abstract：:Four patients developed postural tremor after ingestion of sodium valproate. The tremor was recorded by a variable-capacitance transducer and was of the "benign essential" type. The dosages of sodium valproate varied between 1000 mg and 2000 mg daily and serum levels were between 34.9 microgram per milliliter and 154....

journal_title：Neurology

authors： Hyman NM,Dennis PD,Sinclair KG

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:To study the long-term dual inhibitory effects of rivastigmine on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in patients with AD. METHODS:Eleven patients with mild AD received rivastigmine for 12 months. Cholinesterase (ChE) activities in the CSF and plasma were assessed colorimetrically. ...

journal_title：Neurology

authors： Darreh-Shori T,Almkvist O,Guan ZZ,Garlind A,Strandberg B,Svensson AL,Soreq H,Hellström-Lindahl E,Nordberg A

更新日期：2002-08-27 00:00:00

abstract：:To explore the clinical heterogeneity associated with the Friedreich's ataxia (FRDA) expanded repeat and provide preliminary guidance for future gene testing in patients suspected of having FRDA, we tested patients with typical FRDA (group I), late-onset FRDA or FRDA with retained reflexes (group II), as well as those...

journal_title：Neurology

authors： Geschwind DH,Perlman S,Grody WW,Telatar M,Montermini L,Pandolfo M,Gatti RA

更新日期：1997-10-01 00:00:00

abstract：:Acid protease activity was increased in skeletal muscle of patients with ALS. The highest levels of activity were found in individuals with the clinically and histologically most affected muscle. High levels of proteolytic activity correlated with the extent of muscle atrophy, the presence of target fibers and the ove...

journal_title：Neurology

authors： Antel JP,Chelmicka-Schorr E,Sportiello M,Stefansson K,Wollmann RL,Arnason BG

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVE:To determine whether, and to what degree, preclinical Alzheimer disease (AD) confounds studies of healthy aging where "healthy" is based on cognitive normality alone. METHODS:We examined the effects of preclinical AD in cognitively normal older individuals using resting-state functional connectivity MRI. We ...

journal_title：Neurology

authors： Brier MR,Thomas JB,Snyder AZ,Wang L,Fagan AM,Benzinger T,Morris JC,Ances BM

更新日期：2014-10-28 00:00:00

abstract：OBJECTIVE:To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. METHODS:The study population consisted of 597 patients with MS and 104 control subjects....

journal_title：Neurology

authors： Tedeschi G,Lavorgna L,Russo P,Prinster A,Dinacci D,Savettieri G,Quattrone A,Livrea P,Messina C,Reggio A,Bresciamorra V,Orefice G,Paciello M,Brunetti A,Coniglio G,Bonavita S,Di Costanzo A,Bellacosa A,Valentino P,Quar

更新日期：2005-07-26 00:00:00

abstract：OBJECTIVE:To conduct a systematic review on the association between tetanus vaccination and the risk of multiple sclerosis (MS). METHODS:The authors searched the databases Medline, LILACS, EMBASE, and Science Citation Index including the period 1966 to September 1, 2005. Eligible studies had to meet the following incl...

journal_title：Neurology

authors： Hernán MA,Alonso A,Hernández-Díaz S

更新日期：2006-07-25 00:00:00

abstract：:The incidence of MS was assessed in a nationwide cohort study of 31,990 employees of Danish utility companies between 1900 and 1993. Overall, 32 cases of MS were diagnosed, as compared with 23.7 expected from national incidence rates, to yield a standardized incidence ratio of 1.35 (95% confidence interval, 0.92 to 1....

journal_title：Neurology

authors： Johansen C,Koch-Henriksen N,Rasmussen S,Olsen JH

更新日期：1999-04-12 00:00:00

abstract：:We present six patients with acute fulminant episodes of CNS inflammatory demyelination who responded to therapeutic plasmapheresis after failing a course of high-dose methylprednisolone administered IV. Neurologic improvement occurred in three of the patients following the second plasmapheresis. Dramatic improvement ...

journal_title：Neurology

authors： Rodriguez M,Karnes WE,Bartleson JD,Pineda AA

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, tolerability, and efficacy of glatiramer acetate (GA) 40 mg daily vs the approved 20-mg formulation in relapsing-remitting multiple sclerosis. METHODS:Eligibility criteria included clinically definite multiple sclerosis, Expanded Disability Status Scale score 0 to 5.0, no previous use...

journal_title：Neurology

authors： Cohen JA,Rovaris M,Goodman AD,Ladkani D,Wynn D,Filippi M,9006 Study Group.

更新日期：2007-03-20 00:00:00

abstract：:Treatment of functional symptoms has a long history, and interventions were often used in soldiers returning from battle. On the 75th anniversary of the end of the Second World War, I review the portrayal of neurology in documentary film. Two documentaries were released in 1946 and 1948 (Let There Be Light and Shades ...

journal_title：Neurology

authors： Wijdicks EFM

更新日期：2020-06-09 00:00:00

abstract：:Use of neuroleptic medications is common among elderly patients. Using multivariate models, the authors found that use of antipsychotic medications, age, and disability were strong predictors of developing self-reported Parkinson disease (PD) in the subsequent year among 1992 to 2000 Medicare Current Beneficiary Surve...

journal_title：Neurology

authors： Noyes K,Liu H,Holloway RG

更新日期：2006-03-28 00:00:00

abstract：:We previously reported a large Charcot-Marie-Tooth family not linked to the Duffy blood group marker, supporting the existence of genetic heterogeneity in this neuropathy. In order to investigate the possibility of another disease locus on chromosome 1, we analyzed this family further, using DNA polymorphisms of 6 gen...

journal_title：Neurology

authors： Raeymaekers P,De Jonghe P,Backhovens H,Wehnert A,De Winter G,Swerts L,Gheuens J,Martin JJ,Vandenberghe A,Van Broeckhoven C

更新日期：1989-06-01 00:00:00

abstract：:The authors describe a patient with sporadic distal myopathy associated with reduced caveolin-3 in muscle fibers in which the muscle atrophy was restricted to the small muscles of the hands and feet. Gene analysis disclosed a heterozygous 80 G-->A substitution in the caveolin-3 gene that was identical to that of repor...

journal_title：Neurology

authors： Tateyama M,Aoki M,Nishino I,Hayashi YK,Sekiguchi S,Shiga Y,Takahashi T,Onodera Y,Haginoya K,Kobayashi K,Iinuma K,Nonaka I,Arahata K,Itoyama Y

更新日期：2002-01-22 00:00:00

abstract：:A 42-year-old man had progressive distal weakness and muscle atrophy, stocking-type sensory loss, upper motor-neuron and visual pathway lesions, and dysautonomia. Electrodiagnostic tests revealed a generalized sensorimotor peripheral neuropathy that largely involved axons. Low recumbent and upright norepinephrine leve...

journal_title：Neurology

authors： Rechthand E,Reife R,Kaplan JG

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:To determine the patterns of diffusivity associated with cognitive domain functions in older adults without dementia. METHODS:We studied older adults without dementia (n = 220) who underwent neuropsychometric testing and a diffusion tensor imaging (DTI) examination at 3 T in a cross-sectional study. Memory, ...

journal_title：Neurology

authors： Kantarci K,Senjem ML,Avula R,Zhang B,Samikoglu AR,Weigand SD,Przybelski SA,Edmonson HA,Vemuri P,Knopman DS,Boeve BF,Ivnik RJ,Smith GE,Petersen RC,Jack CR Jr

更新日期：2011-07-05 00:00:00

abstract：:Isovaleric acidemia (IVA) is an inborn error of leucine metabolism, resulting in an accumulation of isovaleric acid in the body fluids. The neuropathologic findings in an 11-day-old infant with IVA consisted of diffuse cerebral edema, massive cerebellar hemorrhage, upward transtentorial herniation, and focal degenerat...

journal_title：Neurology

authors： Fischer AQ,Challa VR,Burton BK,McLean WT

更新日期：1981-06-01 00:00:00

abstract：:The role of gender in the pathogenesis of Alzheimer's disease (AD) is an important issue that remains controversial. We compared men and women in late-onset familial AD kindreds for the risk of developing AD by studying 26 well-characterized familial AD kindreds from the Oregon Alzheimer Disease Center and, for confir...

journal_title：Neurology

authors： Payami H,Montee K,Grimslid H,Shattuc S,Kaye J

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To investigate clinical and economic consequences following generic substitution of one vs multiple generics of topiramate (Topamax; Ortho-McNeil Neurologics, Titusville, NJ). METHODS:Medical and pharmacy claims data of Régie de l'Assurance-Maladie du Québec from January 2006 to October 2007 were used. Patie...

journal_title：Neurology

authors： Duh MS,Paradis PE,Latrémouille-Viau D,Greenberg PE,Lee SP,Durkin MB,Wan GJ,Rupnow MF,LeLorier J

更新日期：2009-06-16 00:00:00

abstract：:A 57-year-old chronically immunosuppressed woman with systemic lupus erythematosus developed fulminant meningoencephalitis due to Acanthamoeba castellanii. Amebic trophozoites were also found in the lungs, suggesting a primary pulmonary focus of infection. This case illustrates that Acanthamoeba can cause a fulminant,...

journal_title：Neurology

authors： Grunnet ML,Cannon GH,Kushner JP

更新日期：1981-02-01 00:00:00

abstract：:A two-octapeptide repeat deletion of the prion protein gene has been recently observed in a patient with a 2-year history of dementia and a clinical diagnosis of possible Creutzfeldt-Jakob disease (CJD). The authors report a similar deletion in a patient with a definitive diagnosis of CJD. Since the two-repeat deletio...

journal_title：Neurology

authors： Capellari S,Parchi P,Wolff BD,Campbell J,Atkinson R,Posey DM,Petersen RB,Gambetti P

更新日期：2002-11-26 00:00:00

abstract：:About 9% of patients presenting to a Huntington disease (HD) clinic for evaluation of possible HD lacked a family history of the disorder. HD was the final diagnosis in 53 to 83% of these patients. As a group, HD-affected individuals without a family history of HD were older and had fewer CAG repeats than the average ...

journal_title：Neurology

authors： Nance MA,Westphal B,Nugent S

更新日期：1996-12-01 00:00:00

abstract：:A patient presented with bilateral brachial plexus neuropathy which 2 weeks later evolved into a polyneuropathy involving all four extremities. On further investigation, the patient was found to have systemic lupus erythematosus. Treatment with steroids was accompanied by complete resolution of the neurologic findings...

journal_title：Neurology

authors： Bloch SL,Jarrett MP,Swerdlow M,Grayzel AI

更新日期：1979-12-01 00:00:00

abstract：:A 47-year-old woman had myasthenia gravis with only moderate weakness and a consistently poor response to anticholinesterase medication. She was investigated with routine electrophysiologic studies and single-fiber electromyography. The studies showed a limited effect of anticholinesterase medication. There was a decr...

journal_title：Neurology

authors： Schwartz MS,Stålberg E

更新日期：1975-01-01 00:00:00

abstract：:We compared 42 myasthenia gravis (MG) patients with thymoma with 42 generalized MG patients without thymoma using a modified Osserman classification. The mean Osserman grades at diagnosis, 6 months, and 5 and 10 years post-thymectomy did not differ between groups. Our results indicate that thymoma is not a negative de...

journal_title：Neurology

authors： Bril V,Kojic J,Dhanani A

更新日期：1998-10-01 00:00:00

abstract：:Spinal cord compression by extramedullary hemopoietic tissue is a rare complication of hemolytic anemias. This is the first report of this complication in hemolytic anemia caused by pyruvate-kinase deficiency. Indium scan, computed tomography (CT) scan, and myelography were helpful in diagnosis. Surgery and radiothera...

journal_title：Neurology

authors： Rutgers MJ,van der Lugt PJ,van Turnhout JM

更新日期：1979-04-01 00:00:00

abstract：:In a 24-week, randomized, double-blind, placebo-controlled, multicenter study of rivastigmine, 487 patients with dementia associated with Parkinson disease underwent assessment of attention on the Cognitive Drug Research computerized cognitive assessment system before dosing and 16 and 24 weeks later. Significant bene...

journal_title：Neurology

authors： Wesnes KA,McKeith I,Edgar C,Emre M,Lane R

更新日期：2005-11-22 00:00:00

abstract：:The long-term evolution of Hu antibody (Hu-Ab) titers in patients with paraneoplastic neurologic syndromes (PNSs) is not known. Described is the evolution of Hu-Ab titers in 35 patients with PNS with a median follow-up of 32 months (range 6 to 108 months). No correlation was observed between Hu-Ab titers and neurologi...

journal_title：Neurology

authors： Lladó A,Mannucci P,Carpentier AF,Paris S,Blanco Y,Saiz A,Delattre JY,Graus F

更新日期：2004-11-23 00:00:00

abstract：:Neurogenic left ventricular dysfunction is a recognized complication of subarachnoid hemorrhage, but this condition has not been reported after seizure activity. The authors present two cases of neurogenic stunned myocardium after convulsive seizures, suggesting that ictal activity can lead to sympathetically mediated...

journal_title：Neurology

authors： Chin PS,Branch KR,Becker KJ

更新日期：2005-06-14 00:00:00

abstract：:A 78-year-old woman presented with a right basal ganglia infarct 6 weeks after a left herpes zoster ophthalmicus. MR angiography showed focal segmental stenosis of the proximal segments of the anterior, middle, and posterior cerebral arteries. Varicella DNA was detected in the CSF by polymerase chain reaction (PCR). T...

journal_title：Neurology

authors： Melanson M,Chalk C,Georgevich L,Fett K,Lapierre Y,Duong H,Richardson J,Marineau C,Rouleau GA

更新日期：1996-08-01 00:00:00