Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes.

Abstract:

:The long-term evolution of Hu antibody (Hu-Ab) titers in patients with paraneoplastic neurologic syndromes (PNSs) is not known. Described is the evolution of Hu-Ab titers in 35 patients with PNS with a median follow-up of 32 months (range 6 to 108 months). No correlation was observed between Hu-Ab titers and neurologic outcome, tumor evolution, or type of treatment. Serial Hu-Ab determinations are not useful for monitoring the clinical outcome of patients with PNS.

journal_name

Neurology

journal_title

Neurology

authors

Lladó A,Mannucci P,Carpentier AF,Paris S,Blanco Y,Saiz A,Delattre JY,Graus F

doi

10.1212/01.wnl.0000144340.03364.bf

subject

Has Abstract

pub_date

2004-11-23 00:00:00

pages

1947-9

issue

10

eissn

0028-3878

issn

1526-632X

pii

63/10/1947

journal_volume

63

pub_type

杂志文章,评审
  • Reemergence of activation with poststroke somatosensory recovery: a serial fMRI case study.

    abstract::The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortic...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.59.5.749

    authors: Carey LM,Abbott DF,Puce A,Jackson GD,Syngeniotis A,Donnan GA

    更新日期:2002-09-10 00:00:00

  • Long-term survival and neurologic status after resuscitation from out-of-hospital cardiac arrest.

    abstract::Thirty-eight survivors from among 117 patients hospitalized after out-of-hospital cardiac arrest were evaluated approximately 3 1/2 years later. Twenty patients were living; 18 had died. Fifty-three percent had resumed independent social activities, but only 32% had returned to work. Eight of 14 patients tested were n...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.30.12.1298

    authors: Earnest MP,Yarnell PR,Merrill SL,Knapp GL

    更新日期:1980-12-01 00:00:00

  • A Japanese boy with myalgia and cramps has a novel in-frame deletion of the dystrophin gene.

    abstract::We report a Japanese Becker muscular dystrophy (BMD) patient with occasional myalgia and cramps during normal activity that developed at the age of 28 months. His family history was negative for neuromuscular diseases. Muscle biopsy analyses, including dystrophin immunostaining, disclosed no clinically relevant findin...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.46.5.1347

    authors: Ishigaki C,Patria SY,Nishio H,Yabe M,Matsuo M

    更新日期:1996-05-01 00:00:00

  • Caloric stimulation and unilateral visual neglect.

    abstract::We studied performance on tests of visual neglect and left lateral gaze after caloric stimulation in 18 patients with left-sided visual neglect after strokes. Except for one patient with absent vestibulo-ocular responses, all improved during caloric stimulation on the left by cold (LC) or on the right by warm water (R...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.35.7.1019

    authors: Rubens AB

    更新日期:1985-07-01 00:00:00

  • Effect of L-carnitine treatment for valproate-induced hepatotoxicity.

    abstract::The authors analyzed the association of L-carnitine treatment with hepatic survival in 92 patients with severe, symptomatic, valproate-induced hepatotoxicity. Forty-eight percent of the 42 patients treated with L-carnitine survived, but only 10% of the 50 patients treated solely with aggressive supportive care survive...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.56.10.1405

    authors: Bohan TP,Helton E,McDonald I,König S,Gazitt S,Sugimoto T,Scheffner D,Cusmano L,Li S,Koch G

    更新日期:2001-05-22 00:00:00

  • A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults.

    abstract::Carbamazepine was compared with phenytoin in a double-blind study. Of 87 patients, data on 70 patients were complete and used for analysis. Thirty-five patients were treated with each drug. The incidence of major side effects, minor side effects, and complete control (85%) was the same in both groups. A mild but signi...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1212/wnl.33.7.904

    authors: Ramsay RE,Wilder BJ,Berger JR,Bruni J

    更新日期:1983-07-01 00:00:00

  • Long-term benefit from prednisone therapy in Duchenne muscular dystrophy.

    abstract::Two successive, 6-month, randomized, double-blind, controlled trials of prednisone showed that 0.75 mg/kg/d was the optimal dose to improve strength in boys with Duchenne muscular dystrophy (DMD). We attempted to maintain 93 boys on that dose for an additional 2 years. During the 3 years of observation, the decline in...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1212/wnl.41.12.1874

    authors: Fenichel GM,Florence JM,Pestronk A,Mendell JR,Moxley RT 3rd,Griggs RC,Brooke MH,Miller JP,Robison J,King W

    更新日期:1991-12-01 00:00:00

  • Rate of spontaneous resolution of a solitary cysticercus granuloma in patients with seizures.

    abstract::The rate of spontaneous resolution of a recently diagnosed solitary cerebral cysticercus granuloma as visualized on CT scan was prospectively studied in 210 patients presenting with seizures. The proportion of granulomas that had resolved completely at different time intervals after the index scan was 18.8% at 3 month...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.12.2315

    authors: Rajshekhar V

    更新日期:2001-12-26 00:00:00

  • AAN position statement: The COVID-19 pandemic and the ethical duties of the neurologist.

    abstract::Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of th...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009744

    authors: Rubin MA,Bonnie RJ,Epstein L,Hemphill C,Kirschen M,Lewis A,Suarez JI,Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society; in collabor

    更新日期:2020-07-28 00:00:00

  • Attentional bias induced by viewing actual or illusory movements.

    abstract:OBJECTIVE:To learn to which portions of a line normal subjects would attend when watching this line actually moving or when perceiving movement even in the absence of actual movement, an illusory movement. METHODS:Twenty normal subjects watched a computer monitor on which either lines or dots moved to the right or lef...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000120546.14213.c7

    authors: Jeong Y,Lee BH,Ahn HJ,Park KC,Heilman KM,Na DL

    更新日期:2004-04-27 00:00:00

  • Quantitative correlation between plasma pyridostigmine levels and neuromuscular function in myasthenia gravis.

    abstract::In 10 patients with myasthenia gravis, we studied the relationship between plasma pyridostigmine levels and five measures of neuromuscular function (NMF) following single oral doses of 60 to 120 mg. The NMF measures were percent decrement of the evoked muscle compound potential, maximum force, force-time integral, vit...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.37.5.800

    authors: Milner-Brown HS,Mellenthin M,Sharma ML,Miller RG

    更新日期:1987-05-01 00:00:00

  • Latency and duration of the muscle silent period following transcranial magnetic stimulation in multiple sclerosis, cerebral ischemia, and other upper motoneuron lesions.

    abstract::In muscles with sustained voluntary contraction, EMG activity is transiently inhibited after transcranial magnetic stimulation. We recorded this postexcitatory silent period (SP) at 1.5 times individual stimulus threshold level from the first dorsal interosseus muscle in 65 neurologic patients aged 11 to 80 years. Whe...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.44.5.936

    authors: Haug BA,Kukowski B

    更新日期:1994-05-01 00:00:00

  • Mild behavioral impairment is linked to worse cognition and brain atrophy in Parkinson disease.

    abstract:OBJECTIVE:To evaluate the associations of mild behavioral impairment (MBI) with cognitive deficits and patterns of gray matter changes in Parkinson disease (PD). METHODS:Sixty patients with PD without dementia and 29 healthy controls underwent a cognitive neuropsychological evaluation and structural MRI scan. MBI was ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000007968

    authors: Yoon EJ,Ismail Z,Hanganu A,Kibreab M,Hammer T,Cheetham J,Kathol I,Sarna JR,Martino D,Furtado S,Monchi O

    更新日期:2019-08-20 00:00:00

  • Investigation of leptomeningeal enhancement in MS: a postcontrast FLAIR MRI study.

    abstract:OBJECTIVE:To investigate possible leptomeningeal contrast enhancement using postcontrast fluid-attenuated inversion recovery (FLAIR) MRI as an additional marker of inflammation in patients with multiple sclerosis (MS). METHODS:A cohort of 112 patients (73 women) with clinically definitive MS or a clinically isolated s...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000001286

    authors: Eisele P,Griebe M,Szabo K,Wolf ME,Alonso A,Engelhardt B,Hennerici MG,Gass A

    更新日期:2015-02-24 00:00:00

  • Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis.

    abstract:OBJECTIVE:This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). METHODS:A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were en...

    journal_title:Neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1212/WNL.0b013e318271f76a

    authors: Meng R,Asmaro K,Meng L,Liu Y,Ma C,Xi C,Li G,Ren C,Luo Y,Ling F,Jia J,Hua Y,Wang X,Ding Y,Lo EH,Ji X

    更新日期:2012-10-30 00:00:00

  • Journal club: pretreatment EEG in childhood absence epilepsy.

    abstract::Childhood absence epilepsy (CAE) is defined by absence seizures in a normally developing child, with onset between 4 and 10 years of age.(1) Typical absence seizures consist of behavioral arrest with or without automatisms, usually last 30-60 seconds, and demonstrate a characteristic 3-Hz generalized spike-wave (GSW) ...

    journal_title:Neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1212/WNL.0000000000000380

    authors: Bernson-Leung ME,Mazumdar M

    更新日期:2014-05-06 00:00:00

  • Apolipoprotein E and functional recovery from brain injury following postacute rehabilitation.

    abstract:OBJECTIVE:APOE epsilon4 has been associated with late-onset familial and sporadic AD and delayed recovery from head injury. The authors examined the relationship between functional recovery of patients with head injury and the APOE alleles. METHODS:Thirty-one patients with head injury who had completed the Acute Neuro...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.55.10.1536

    authors: Lichtman SW,Seliger G,Tycko B,Marder K

    更新日期:2000-11-28 00:00:00

  • Cervical dural sac and spinal cord in juvenile muscular atrophy of distal upper extremity.

    abstract:OBJECTIVE:To investigate specificity and significance of dynamic changes of the cervical dural sac and spinal cord during neck flexion in juvenile muscular atrophy of the distal upper extremity. BACKGROUND:The disorder affects young people-predominantly men-and is progressive for several years. One autopsy case showed...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.10.1922

    authors: Hirayama K,Tokumaru Y

    更新日期:2000-05-23 00:00:00

  • Incidence of seizures with phenytoin toxicity.

    abstract::Among 50 patients with phenytoin intoxication, 14 had seizures during the episode. Seizures in 9 of these 14 patients probably resulted from poor seizure control despite high phenytoin levels, but in 5 cases, attacks were attributed to phenytoin toxicity. The only factor that seemed to correlate with seizures was a se...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.35.12.1769

    authors: Stilman N,Masdeu JC

    更新日期:1985-12-01 00:00:00

  • Distribution of partial seizures during the sleep--wake cycle: differences by seizure onset site.

    abstract:OBJECTIVE:To evaluate the effects of sleep on partial seizures arising from various brain regions. METHODS:The authors prospectively studied 133 patients with localization-related epilepsy undergoing video-EEG monitoring over a 2-year period. Seizure type, site of onset, sleep/wake state at onset, duration, and epilep...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.56.11.1453

    authors: Herman ST,Walczak TS,Bazil CW

    更新日期:2001-06-12 00:00:00

  • Severe dysarthria with right hemisphere stroke.

    abstract::Ten patients are presented with severe dysarthria from a right hemisphere stroke, 4 with autopsies, emphasizing that this lesion alone is compatible with severely slurred speech. Most had oropharyngeal weakness; the accompanying hemiparesis was of variable severity. Superficial or deep infarctions were responsible, th...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.37.6.1061

    authors: Ropper AH

    更新日期:1987-06-01 00:00:00

  • Competency to consent to medical treatment in cognitively impaired patients with Parkinson's disease.

    abstract:OBJECTIVES:To investigate capacity to consent to medical treatment (competency) in cognitively impaired patients with PD. BACKGROUND:Although competency has been studied empirically in patients with cortical dementia (AD), no empirical studies have examined competency in patients with PD or other subcortical neurodege...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.56.1.17

    authors: Dymek MP,Atchison P,Harrell L,Marson DC

    更新日期:2001-01-09 00:00:00

  • Correlation of enzyme-inducing anticonvulsant use with outcome of patients with glioblastoma.

    abstract:BACKGROUND:Clinical trials involving patients with glioblastoma (GBM) distinguish cohorts who are treated with enzyme-inducing anticonvulsants (EIAC). Such anticonvulsants induce hepatic P450 microsomal enzymes, which accelerate the metabolism of certain chemotherapy and molecular targeted agents. However, the resultan...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181bbfeca

    authors: Jaeckle KA,Ballman K,Furth A,Buckner JC

    更新日期:2009-10-13 00:00:00

  • Basal ganglia pathology in ALS is associated with neuropsychological deficits.

    abstract:OBJECTIVES:To evaluate basal ganglia changes along the amyotrophic lateral sclerosis (ALS)-ALS-frontotemporal dementia (FTD) continuum using multiple, complementary imaging techniques. METHODS:Sixty-seven C9orf72-negative patients with ALS and 39 healthy controls were included in a cross-sectional quantitative MRI stu...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000002017

    authors: Machts J,Loewe K,Kaufmann J,Jakubiczka S,Abdulla S,Petri S,Dengler R,Heinze HJ,Vielhaber S,Schoenfeld MA,Bede P

    更新日期:2015-10-13 00:00:00

  • The prevalence of MS in the United States: A population-based estimate using health claims data.

    abstract:OBJECTIVE:To generate a national multiple sclerosis (MS) prevalence estimate for the United States by applying a validated algorithm to multiple administrative health claims (AHC) datasets. METHODS:A validated algorithm was applied to private, military, and public AHC datasets to identify adult cases of MS between 200...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000007035

    authors: Wallin MT,Culpepper WJ,Campbell JD,Nelson LM,Langer-Gould A,Marrie RA,Cutter GR,Kaye WE,Wagner L,Tremlett H,Buka SL,Dilokthornsakul P,Topol B,Chen LH,LaRocca NG,US Multiple Sclerosis Prevalence Workgroup.

    更新日期:2019-03-05 00:00:00

  • The biphasic pattern of age-specific malignant brain tumor mortality rates.

    abstract::Many aging-associated neurologic disorders, including primary malignant brain tumors (MBT), share a common biphasic age-specific mortality rate pattern: initially increasing exponentially with age, and then declining. A modeling study using MBT mortality was conducted to determine if the observed biphasic pattern of M...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/wnl.55.6.750

    authors: Riggs JE

    更新日期:2000-09-26 00:00:00

  • Amino acid abnormalities in cerebrospinal fluid of patients with parkinsonism and extrapyramidal disorders.

    abstract::Free amino acid determinations in the cerebrospinal fluid of patients with Parkinson's disease or other extrapyramidal disorders showed that in both groups most amino acids were increased. Significantly increased amino acids were neutral and basic amino acids. Amino acid clusters were present and corresponded with the...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.26.5.489

    authors: Lakke JP,Teelken AW

    更新日期:1976-05-01 00:00:00

  • 18F-FDG-PET correlates of cognitive impairment in ALS.

    abstract:OBJECTIVE:To identify the metabolic signature of the various levels of cognitive deficits in amyotrophic lateral sclerosis (ALS) using 18F-2-fluoro-2-deoxy-d-glucose-PET (18F-FDG-PET). METHODS:A total of 170 ALS cases consecutively enrolled at the ALS Center of Turin underwent brain 18F-FDG-PET and were classified as ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000002242

    authors: Canosa A,Pagani M,Cistaro A,Montuschi A,Iazzolino B,Fania P,Cammarosano S,Ilardi A,Moglia C,Calvo A,Chiò A

    更新日期:2016-01-05 00:00:00

  • Normal pressure hydrocephalus, parkinsonism, and primary empty sella--coincidence or cause-effect?

    abstract::The triad of normal-pressure hydrocephalus, parkinsonism, and primary empty sella appeared in a 70-year-old woman. There was dramatic resolution of the extrapyramidal signs and symptoms on treatment with levodopa-carbidopa and ventriculojugular shunt. The syndrome may be the result of several mechanisms, but an altera...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.11.1191

    authors: Spagna VA,Maeder MC,Johnson JC,Mazzaferri EL

    更新日期:1978-11-01 00:00:00

  • Effect of insurance status on postacute care among working age stroke survivors.

    abstract:OBJECTIVE:Utilization of postacute care is associated with improved poststroke outcomes. However, more than 20% of American adults under age 65 are uninsured. We sought to determine whether insurance status is associated with utilization and intensity of institutional postacute care among working age stroke survivors. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3182563bf5

    authors: Skolarus LE,Meurer WJ,Burke JF,Prvu Bettger J,Lisabeth LD

    更新日期:2012-05-15 00:00:00