Abstract:
:We identified seven patients with refractory partial epilepsy and sleep apnea. Treatment of the sleep apnea with nasal continuous positive airway pressure (CPAP), protriptyline, trazodone, acetazolamide, or tracheostomy reduced seizure frequency and severity in six patients. Success with CPAP depended largely on compliance. Four of five patients had a clear reduction in seizure frequency with the use of CPAP. Sleep apnea may exacerbate epilepsy by causing sleep disruption and deprivation, hypoxemia, and decreased cerebral blood flow. In epilepsy patients with risk factors (eg, obesity) or markers (eg, habitual snoring, daytime somnolence) for sleep apnea, a careful sleep history should be elicited and a polysomnogram obtained when indicated. Treatment of the sleep disorder can improve seizure control.
journal_name
Neurologyjournal_title
Neurologyauthors
Devinsky O,Ehrenberg B,Barthlen GM,Abramson HS,Luciano Ddoi
10.1212/wnl.44.11.2060subject
Has Abstractpub_date
1994-11-01 00:00:00pages
2060-4issue
11eissn
0028-3878issn
1526-632Xjournal_volume
44pub_type
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