Abstract:
:A 71-year-old man developed severe limb, bulbar, and respiratory weakness over 18 months. A muscle biopsy showed only a moderate degree of type 2 atrophy, but immunocytochemistry showed absence of chondroitin sulfate C glycosaminoglycan in the endomysium. Prednisone produced a marked increase in strength. Diffuse loss of endomysial chondroitin sulfate C was a feature of this treatable myopathy with severe weakness, but few pathologic changes.
journal_name
Neurologyjournal_title
Neurologyauthors
al-Lozi MT,Hemelt VB,Pestronk Adoi
10.1212/wnl.50.2.526subject
Has Abstractpub_date
1998-02-01 00:00:00pages
526-9issue
2eissn
0028-3878issn
1526-632Xjournal_volume
50pub_type
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