Infarcts with a cardiac source of embolism in the NINCDS Stroke Data Bank: historical features.

abstract：OBJECTIVE:To determine the prevalence, incidence, and predictors of epilepsy among older adults in the Cardiovascular Health Study (CHS). METHODS:We analyzed data prospectively collected in CHS and merged with data from outpatient Medicare administrative claims. We identified cases with epilepsy using self-report, ant...

journal_title：Neurology

authors： Choi H,Pack A,Elkind MS,Longstreth WT Jr,Ton TG,Onchiri F

更新日期：2017-02-28 00:00:00

abstract：:We determined the horizontal and vertical components of brain displacement on coronal MRIs in 10 patients with acute supratentorial masses. The vertical distances from the superior sagittal sinus to the pontomesencephalic junction (PMJ) and from the vertical midline of the brain to the PMJ did not differ from measurem...

journal_title：Neurology

authors： Ropper AH

更新日期：1989-05-01 00:00:00

abstract：:The authors estimated the sample sizes needed for exploratory trials of MS assessing the efficacy of new treatments in reducing the number of new enhancing lesions vs those of interferon-beta or glatiramer acetate. The sample sizes per arm ranged from 868 (effect: 20%) to 94 (effect: 50%) for patients with relapsing-r...

journal_title：Neurology

authors： Sormani MP,Rovaris M,Bagnato F,Molyneux P,Bruzzi P,Pozzilli C,Miller DH,Comi G,Filippi M

更新日期：2001-11-27 00:00:00

abstract：:Anti-Leu 7 antibody reacts with determinants on a subset of natural killer (NK) cells and myelin-associated glycoprotein (MAG). In a patient patient with peripheral neuropathy and IgM autoantibodies against MAG, we found the distribution and functions of NK cells to be normal. ...

journal_title：Neurology

authors： Sriram S,Lanier L

更新日期：1986-04-01 00:00:00

abstract：:Disturbed deglutition is common in diseases of the brainstem and lower cranial nerves, but little is known about the mechanisms involved. We studied a 49-year-old man with symptoms of syringomyelia and syringobulbia lasting 7 years. Esophageal motility studies showed inability to initiate swallowing, esophageal hypomo...

journal_title：Neurology

authors： Bleck TP,Shannon KM

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Using a stereologic approach, the density of nerve fibers innervating sweat gland (SG) fragments in patients with diabetes mellitus (DM) and healthy controls using protein gene product (PGP), tyrosine hydroxylase (TH), and vasoactive intestinal peptide (VIP) was measured to determine which marker best detect...

journal_title：Neurology

authors： Liu Y,Billiet J,Ebenezer GJ,Pan B,Hauer P,Wei J,Polydefkis M

更新日期：2015-04-21 00:00:00

abstract：:There has been disagreement about the precise characteristics of "subcortical aphasia." We evaluated 14 patients with aphasia after subcortical lesions and controlled for duration, general anatomic site of lesions (capsulostriatal only), and etiology. The clinical profiles of the patients were quite similar, varying i...

journal_title：Neurology

authors： Mega MS,Alexander MP

更新日期：1994-10-01 00:00:00

abstract：:T, B, and "null" lymphocytes were determined in peripheral blood obtained from 24 control subjects and 15 multiple sclerosis patients. The total number of lymphocytes and T lymphocytes were reduced significantly in multiple sclerosis patients as compared with those of controls. Although the percentage of B lymphocytes...

journal_title：Neurology

authors： Reddy MM,Goh KO

更新日期：1976-10-01 00:00:00

abstract：:Six members of a family had a neurologic disease with autosomal dominant transmission and adolescent onset of progressive wasting of predominantly distal axial muscles and muscles innervated by cranial nerves V, VII, X, and XII, leading to severe morbidity in adulthood. Muscle biopsy of the propositus revealed "ragged...

journal_title：Neurology

authors： Dobkin BH,Verity MA

更新日期：1976-08-01 00:00:00

abstract：OBJECTIVE:APOE ε2 and ε4 alleles have been associated with lobar intracerebral hemorrhage (ICH) in predominately white populations; we sought to evaluate whether this held true among black and Hispanic populations. METHODS:The Ethnic/Racial Variations of Intracerebral Hemorrhage study is a prospective, multicenter cas...

journal_title：Neurology

authors： Sawyer RP,Sekar P,Osborne J,Kittner SJ,Moomaw CJ,Flaherty ML,Langefeld CD,Anderson CD,Rosand J,Woo D

更新日期：2018-07-31 00:00:00

abstract：OBJECTIVE:To determine the associations between amyloid-PET, tau-PET, and atrophy with the behavioral/dysexecutive presentation of Alzheimer disease (AD), how these differ from amnestic AD, and how they correlate to clinical symptoms. METHODS:We assessed 15 patients with behavioral/dysexecutive AD recruited from a ter...

journal_title：Neurology

authors： Therriault J,Pascoal TA,Savard M,Benedet AL,Chamoun M,Tissot C,Lussier F,Kang MS,Thomas E,Terada T,Rej S,Massarweh G,Nasreddine Z,Vitali P,Soucy JP,Saha-Chaudhuri P,Gauthier S,Rosa-Neto P

更新日期：2021-01-05 00:00:00

abstract：OBJECTIVES:Many patients with traumatic brain injury (TBI) report chronic fatigue, and previous studies showed a potential relationship between sleepiness and fatigue in these patients. Our study first looked at the impact of objective and subjective sleepiness on fatigue in patients with TBI. We then investigated how ...

journal_title：Neurology

authors： Chaumet G,Quera-Salva MA,Macleod A,Hartley S,Taillard J,Sagaspe P,Mazaux JM,Azouvi P,Joseph PA,Guilleminault C,Bioulac B,Léger D,Philip P

更新日期：2008-11-11 00:00:00

abstract：:We observed acute onset of delayed psychosis in 8 patients 1 month to 11 years after right temporoparietooccipital (TPO) stroke or trauma. The psychotic disorder included hallucinations and, in some patients delusions and agitation. All patients had spatioconstructional difficulties. None had an earlier psychiatric di...

journal_title：Neurology

authors： Levine DN,Finklestein S

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:The paradoxical phenomenon of relative longevity among obese patients with established diseases has been reported for various disease conditions. The authors sought to investigate whether the obesity paradox also applies to intracerebral hemorrhage (ICH) survivors. METHODS:A total of 1,604 patients with ICH...

journal_title：Neurology

authors： Kim BJ,Lee SH,Ryu WS,Kim CK,Lee J,Yoon BW

更新日期：2011-02-08 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be associated with neurocognitive deficits. The Hemophilia Growth and Development Study enrolled HIV-infected and HIV-uninfected patients and a group of nonhemophiliac siblings. After controlling for multiple factors, HCV monoinfection was not associated with deficits in adaptive ...

journal_title：Neurology

authors： Soogoor M,Lynn HS,Donfield SM,Gomperts E,Bell TS,Daar ES,Hemophilia Growth and Development Study.

更新日期：2006-10-24 00:00:00

abstract：OBJECTIVE:The present retrospective cohort study compares the long-term functional outcome, improvement or deterioration, of patients considered in a vegetative state (VS) or a minimally conscious state (MCS) 1 year after coma onset, then yearly for up to 5 years. METHODS:We reviewed the clinical courses of 12 patient...

journal_title：Neurology

authors： Luauté J,Maucort-Boulch D,Tell L,Quelard F,Sarraf T,Iwaz J,Boisson D,Fischer C

更新日期：2010-07-20 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of childhood ataxia resulting from both genetic and acquired causes. METHODS:A systematic review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement. Five databases were searched for articles reporting a frequency measur...

journal_title：Neurology

authors： Musselman KE,Stoyanov CT,Marasigan R,Jenkins ME,Konczak J,Morton SM,Bastian AJ

更新日期：2014-01-07 00:00:00

abstract：:To determine the frequency of subjective sleep problems in spinocerebellar ataxia type 6 (SCA6), the authors surveyed 25 patients and 25 age-matched controls with the Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). The ESS was higher in patients with SCA6 (9.12 +/- 5.80; CI: 2.28) than in con...

journal_title：Neurology

authors： Howell MJ,Mahowald MW,Gomez CM

更新日期：2006-05-09 00:00:00

abstract：OBJECTIVE:To investigate whether the presence of cerebral microbleeds, which present as focal lesions on imaging, is associated with a diffuse loss of white matter microstructural integrity in the brain. METHODS:In the prospective, population-based Rotterdam Scan Study, a total of 4,493 participants underwent brain MR...

journal_title：Neurology

authors： Akoudad S,de Groot M,Koudstaal PJ,van der Lugt A,Niessen WJ,Hofman A,Ikram MA,Vernooij MW

更新日期：2013-11-26 00:00:00

abstract：:The concept of earlier diagnosis of amyotrophic lateral sclerosis (ALS) requires in-depth investigation of its benefits and consequences. First, how good must a treatment be before ALS is determined to be a treatable condition? Analogy with cancer therapy suggests that a good quality of life after treatment is an esse...

journal_title：Neurology

authors： Brooks BR

更新日期：1999-01-01 00:00:00

abstract：:The aim of this randomized, double-blind, placebo-controlled cross-over study was to test whether valproic acid relieves painful polyneuropathy. Thirty-one patients completed two treatment phases of 4 weeks' duration with valproic acid (1,500 mg daily) and placebo. There was no significant difference between valproic ...

journal_title：Neurology

authors： Otto M,Bach FW,Jensen TS,Sindrup SH

更新日期：2004-01-27 00:00:00

abstract：:To elucidate the possible role of vitamin E in the pathogenesis of Parkinson's disease (PD), we compared serum levels of alpha-tocopherol (vitamin E), measured by high-performance liquid chromatography, and the vitamin E/cholesterol ratio of 42 Parkinson's disease (PD) patients using their spouses as the control group...

journal_title：Neurology

authors： Férnandez-Calle P,Molina JA,Jiménez-Jiménez FJ,Vázquez A,Pondal M,García-Ruiz PJ,Urra DG,Domingo J,Codoceo R

更新日期：1992-05-01 00:00:00

abstract：:The authors studied immunoglobulin G (IgG) Fc receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms in 62 patients with Guillain-Barré syndrome (GBS) and in 89 healthy controls. The FcgammaR genotypes and allele frequencies did not differ significantly between the patients with GBS and the controls. Patients homozygou...

journal_title：Neurology

authors： Vedeler CA,Raknes G,Myhr KM,Nyland H

更新日期：2000-09-12 00:00:00

abstract：:Article abstract Depressive disorders (DDs) are the most common type of psychiatric co-morbidity in patients with epilepsy. They are more likely to occur in patients with partial seizure disorders of temporal and frontal lobe origin and are more frequent among patients with poorly controlled seizures. Despite their re...

journal_title：Neurology

authors： Kanner AM,Balabanov A

更新日期：2002-04-23 00:00:00

abstract：:Three sisters with adult fucosidosis showed prominent psychomotor retardation, gargoyle features, and angiokeratoma corporis diffusum, meeting the criteria for type II fucosidosis. By histochemical and ultrastructural studies, biopsy of rectal mucosa revealed many abnormal macrophages that were filled with fucose-rich...

journal_title：Neurology

authors： Ikeda S,Kondo K,Oguchi K,Yanagisawa N,Horigome R,Murata F

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Idiopathic REM sleep behavior disorder (RBD) is characterized by loss of atonia during REM sleep, resulting in motor activity during dreams. Studies estimate that approximately half of patients with RBD will eventually develop Parkinson disease (PD), so RBD may be an indicator of presymptomatic PD. Several p...

journal_title：Neurology

authors： Postuma RB,Lang AE,Massicotte-Marquez J,Montplaisir J

更新日期：2006-03-28 00:00:00

abstract：BACKGROUND:Treatment of aneurysmal subarachnoid hemorrhage (SAH) has changed substantially over the last 25 years but there is a lack of reliable population-based data on whether case-fatality or functional outcomes have improved. METHODS:We determined changes in the standardized incidence and outcome of SAH in the sa...

journal_title：Neurology

authors： Lovelock CE,Rinkel GJ,Rothwell PM

更新日期：2010-05-11 00:00:00

abstract：OBJECTIVE:To determine whether the cytokine tumor necrosis factor alpha (TNF-alpha) acts as a pain mediator in neuropathic pain in humans. BACKGROUND:In animal models, inflammatory cytokines such as TNF-alpha have been shown to facilitate neuropathic pain. METHODS:The expression of TNF-alpha was analyzed immunohistoc...

journal_title：Neurology

authors： Empl M,Renaud S,Erne B,Fuhr P,Straube A,Schaeren-Wiemers N,Steck AJ

更新日期：2001-05-22 00:00:00

abstract：:Quantitative studies of the afferent pathways from hollow viscera have been limited by the lack of an easily controlled, reproducible visceral stimulus. We adapted a slow distention device to allow for rapid distention to study the afferent pathways from the rectum. The device produced a pressure increase of 10 mm Hg ...

journal_title：Neurology

authors： Loening-Baucke V,Anderson RH,Yamada T,Zhu YX

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The epsilon 4 allele of the APOE gene (APOE) is more frequent in patients with AD than in the general population, but studies are inconclusive as to whether it affects rate of progression or survival. Because survival in AD is generally longer in women than in men, the authors investigated whether APOE affec...

journal_title：Neurology

authors： Dal Forno G,Carson KA,Brookmeyer R,Troncoso J,Kawas CH,Brandt J

更新日期：2002-04-09 00:00:00