Inverse cerebellum and occipital encephalocele. A dorsal fusion defect uniting the Arnold-Chiari and Dandy-Walker spectrum.

abstract：BACKGROUND:In the late 19th century, a man with a psychogenic movement disorder was evaluated by many of the Philadelphia neurologists associated with Silas Weir Mitchell. In 1885, prior to the development of movie cameras or projectors, the patient was photographed by pioneering photographer Eadweard Muybridge, in col...

journal_title：Neurology

authors： Lanska DJ

更新日期：2015-01-27 00:00:00

abstract：OBJECTIVE:To examine whether the incidence, comorbidity, and mortality of first-time ischemic stroke changed in Denmark between 1996 and 2016 overall and according to age and sex using a nationwide cohort design. METHODS:In this cohort study, 224,617 individuals ≥18 years of age admitted with first-time ischemic strok...

journal_title：Neurology

authors： Yafasova A,Fosbøl EL,Christiansen MN,Vinding NE,Andersson C,Kruuse C,Johnsen SP,Gislason GH,Torp-Pedersen C,Køber L,Butt JH

更新日期：2020-10-27 00:00:00

abstract：:A 71-year-old man developed severe limb, bulbar, and respiratory weakness over 18 months. A muscle biopsy showed only a moderate degree of type 2 atrophy, but immunocytochemistry showed absence of chondroitin sulfate C glycosaminoglycan in the endomysium. Prednisone produced a marked increase in strength. Diffuse loss...

journal_title：Neurology

authors： al-Lozi MT,Hemelt VB,Pestronk A

更新日期：1998-02-01 00:00:00

abstract：:This multicenter, double-blind, crossover study compared Tegretol-XR and Tegretol tablets with respect to trough plasma carbamazepine (CBZ) concentrations, seizure control, tolerability, and safety. We randomized 96 patients with epilepsy to 56-day monotherapy with their usual daily CBZ dose administered as (1) Tegret...

journal_title：Neurology

authors：

更新日期：1995-09-01 00:00:00

abstract：:The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortic...

journal_title：Neurology

authors： Carey LM,Abbott DF,Puce A,Jackson GD,Syngeniotis A,Donnan GA

更新日期：2002-09-10 00:00:00

abstract：OBJECTIVE:The aim of this study was to review 4 patients with encephalomyeloradiculoneuropathy (EMRN) and assess for autoantibodies against neutral glycolipids. METHODS:We studied the progression of clinical, radiologic, neurophysiologic, and CSF findings, as well as anti-neutral glycolipid antibodies in sera. RESULT...

journal_title：Neurology

authors： Shima S,Kawamura N,Ishikawa T,Masuda H,Iwahara C,Niimi Y,Ueda A,Iwabuchi K,Mutoh T

更新日期：2014-01-14 00:00:00

abstract：OBJECTIVES:(1) To assess the diagnostic accuracy of EMG in radiculopathy. (2) To evaluate the intrarater reliability and interrater reliability of EMG in radiculopathy. (3) To assess the presence of confirmation bias in EMG. METHODS:Three experienced academic electromyographers interpreted 3 compact discs with 20 EMG ...

journal_title：Neurology

authors： Narayanaswami P,Geisbush T,Jones L,Weiss M,Mozaffar T,Gronseth G,Rutkove SB

更新日期：2016-01-19 00:00:00

abstract：BACKGROUND:Several lines of evidence suggest that inflammatory mechanisms contribute to AD. OBJECTIVE:To examine whether several markers of inflammation are associated with cognitive decline in African-American and white well-functioning elders. METHODS:The authors studied 3,031 African-American and white men and wom...

journal_title：Neurology

authors： Yaffe K,Lindquist K,Penninx BW,Simonsick EM,Pahor M,Kritchevsky S,Launer L,Kuller L,Rubin S,Harris T

更新日期：2003-07-08 00:00:00

abstract：:Essential tremor (ET) is a common movement disorder that often causes functional disability, potentially leading to physical and emotional difficulties. The paucity of data available regarding the underlying pathophysiologic mechanism of ET hinders the development of innovative approaches to pharmacotherapeutic treatm...

journal_title：Neurology

authors： Koller WC,Hristova A,Brin M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To discuss the indications and timing for resective surgery in patients with Sturge-Weber syndrome (SWS) and medication-resistant epilepsy. BACKGROUND:SWS that causes epilepsy severe enough to merit surgery is rare. Because of the variable natural history of the disease, it is difficult to establish clear-cu...

journal_title：Neurology

authors： Arzimanoglou AA,Andermann F,Aicardi J,Sainte-Rose C,Beaulieu MA,Villemure JG,Olivier A,Rasmussen T

更新日期：2000-11-28 00:00:00

abstract：:We performed a retrospective study on a series of 119 of our patients who have Friedreich's disease to assess the predictive value of age at onset, gender, and left ventricular hypertrophy in regard to disease progression. Outcome variables were survival, time to loss of independent gait, and time to confinement in a ...

journal_title：Neurology

authors： De Michele G,Perrone F,Filla A,Mirante E,Giordano M,De Placido S,Campanella G

更新日期：1996-11-01 00:00:00

abstract：:We studied 15 dystonic patients with positron emission tomography (PET) and (18F)-2-fluoro-2-deoxy-D-glucose (FDG). The group comprised patients with focal (n = 5), multifocal (n = 1), and generalized (n = 4) dystonia as well as patients with hemidystonia (n = 5). The age at onset was during childhood in four, during ...

journal_title：Neurology

authors： Karbe H,Holthoff VA,Rudolf J,Herholz K,Heiss WD

更新日期：1992-08-01 00:00:00

abstract：:Erythrocyte calcium transport as a function of free [Ca++] was examined using inside-out vesicles from eight pairs of patients with Duchenne dystrophy and age- and sex-matched controls. The Km for Ca++ of the transport protein and the Vmax were higher in the Duchenne vesicles in seven of the eight pairs. The mean Km a...

journal_title：Neurology

authors： Mollman JE,Cardenas JC,Pleasure DE

更新日期：1980-11-01 00:00:00

abstract：:The authors report three patients with acute, chronic, and recurrent neuropathy associated with varicella zoster virus (VZV) infection but without zoster rash. CSF of all three patients contained VZV immunoglobulin G antibody, but not herpes simplex virus. In two patients, serum/CSF ratios of VZV immunoglobulin G were...

journal_title：Neurology

authors： Fox RJ,Galetta SL,Mahalingam R,Wellish M,Forghani B,Gilden DH

更新日期：2001-07-24 00:00:00

abstract：:Fatal familial insomnia (FFI), a condition characterized by inability to sleep, dysautonomia, motor disturbances, and selective thalamic atrophy is a prion disease linked to a GAC----AAC mutation at codon 178 of the prion gene. These data were obtained from one kindred. We now report a second kindred affected by FFI a...

journal_title：Neurology

authors： Medori R,Montagna P,Tritschler HJ,LeBlanc A,Cortelli P,Tinuper P,Lugaresi E,Gambetti P

更新日期：1992-03-01 00:00:00

abstract：:Primary deficiency of merosin is the cause of the classic form of congenital muscular dystrophy (CMD) accompanied by brain white matter abnormalities. We report a female infant with dystrophinopathy who was deficient in merosin in skeletal muscle. The patient had a phenotype of typical CMD and white matter abnormaliti...

journal_title：Neurology

authors： Tachi N,Ohya K,Chiba S,Matsuo M,Patria SY,Matsumura K

更新日期：1997-08-01 00:00:00

abstract：:Behavioral testing following division of the corpus callosum has shown that the anterior commissure can transfer information related to visual tasks interhemispherically in nonhuman primates but not in humans. We have found that the ratio of anterior commissure cross-sectional area to total neocortical commissural are...

journal_title：Neurology

authors： Foxman BT,Oppenheim J,Petito CK,Gazzaniga MS

更新日期：1986-11-01 00:00:00

abstract：:Two women with myasthenia gravis became apneic immediately after IV injection of iodinated contrast material for CT. Aggravation of myasthenia continued for days after this initial reaction. ...

journal_title：Neurology

authors： Chagnac Y,Hadani M,Goldhammer Y

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:To investigate patient susceptibility to neuropsychiatric symptoms in the context of progression of more classic motor symptoms in amyotrophic lateral sclerosis (ALS) and to examine the impact of neuropsychiatric symptoms on survival. METHODS:The study cohort consisted of 219 patients with ALS (limb onset =...

journal_title：Neurology

authors： Mioshi E,Caga J,Lillo P,Hsieh S,Ramsey E,Devenney E,Hornberger M,Hodges JR,Kiernan MC

更新日期：2014-01-14 00:00:00

abstract：OBJECTIVE:To study the difference in risk for dementing diseases between men and women. BACKGROUND:Previous studies suggest women have a higher risk for dementia than men. However, these studies include small sample sizes, particularly in the older age groups, when the incidence of dementia is highest. METHODS:Pooled...

journal_title：Neurology

authors： Andersen K,Launer LJ,Dewey ME,Letenneur L,Ott A,Copeland JR,Dartigues JF,Kragh-Sorensen P,Baldereschi M,Brayne C,Lobo A,Martinez-Lage JM,Stijnen T,Hofman A

更新日期：1999-12-10 00:00:00

abstract：OBJECTIVE:To determine whether groups of surrogates for patients with severe acute brain injury (SABI) with poor prognosis can be identified based on their prioritization of goals-of-care (GOC) decisional concerns, an online survey of 1,588 adults recruited via a probability-based panel representative of the US populat...

journal_title：Neurology

authors： Hwang DY,Knies AK,Mampre D,Kolenikov S,Schalk M,Hammer H,White DB,Holloway RG,Sheth KN,Fraenkel L

更新日期：2020-05-12 00:00:00

abstract：:The authors searched for mutations in CACNA1A in patients with episodic ataxia and describe the clinical spectrum in genetically defined patients. Eighteen families and nine sporadic cases of episodic ataxia were evaluated for mutations in CACNA1A. The families were first genotyped to check for linkage to the chromoso...

journal_title：Neurology

authors： Jen J,Kim GW,Baloh RW

更新日期：2004-01-13 00:00:00

abstract：:Alzheimer's disease is characterized by relative sparing of primary sensory and motor cortex and a lack of sensory or motor symptomatology. We report a case of presenile onset dementia accompanied by a slowly progressive hemiparesis. Autopsy examination showed severe pathologic involvement of somatosensory cortex with...

journal_title：Neurology

authors： Jagust WJ,Davies P,Tiller-Borcich JK,Reed BR

更新日期：1990-01-01 00:00:00

abstract：:The intracarotid amobarbital test (IAT) examines hemispheric memory and language. We set out to determine whether memory performance on the IAT correlated with seizure relief after anterior temporal lobectomy in 117 patients with refractory epilepsy. The IAT assessed recognition memory performance for nine items with ...

journal_title：Neurology

authors： Sperling MR,Saykin AJ,Glosser G,Moran M,French JA,Brooks M,O'Connor MJ

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To describe a kindred with a dominantly inherited neurologic disorder manifested either as uncomplicated spastic paraplegia or ataxia, spastic paraplegia, and mental retardation. METHODS:Neurologic examinations and molecular genetic analysis (exclusion of known SCA and HSP genes and loci; and trinucleotide r...

journal_title：Neurology

authors： Hedera P,Rainier S,Zhao XP,Schalling M,Lindblad K,Yuan QP,Ikeuchi T,Trobe J,Wald JJ,Eldevik OP,Kluin K,Fink JK

更新日期：2002-02-12 00:00:00

abstract：OBJECTIVES:Observational and experimental studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer disease (AD); however, clinical trials and other observational studies, including the Adult Changes in Thought (ACT) study, show no protection or promotion of AD. The objective of t...

journal_title：Neurology

authors： Sonnen JA,Larson EB,Walker RL,Haneuse S,Crane PK,Gray SL,Breitner JC,Montine TJ

更新日期：2010-09-28 00:00:00

abstract：BACKGROUND:In cerebral small vessel disease, the core MRI findings include white matter lesions (WML) and lacunar infarcts. While the clinical significance of WML is better understood, the contribution of lacunes to the rate of cognitive decline has not been established. This study investigated whether incident lacunes...

journal_title：Neurology

authors： Jokinen H,Gouw AA,Madureira S,Ylikoski R,van Straaten EC,van der Flier WM,Barkhof F,Scheltens P,Fazekas F,Schmidt R,Verdelho A,Ferro JM,Pantoni L,Inzitari D,Erkinjuntti T,LADIS Study Group.

更新日期：2011-05-31 00:00:00

abstract：:Oligoclonal bands ( OCBs ) were examined in CSF from 23 normal controls, 8 cases of inflammatory neurologic diseases, 24 cases of noninflammatory neurologic diseases, 27 sporadic cases of MS, and the 29 MS twin pairs, by isoelectric focusing followed by silver staining or western transblotting and immunoperoxidase sta...

journal_title：Neurology

authors： Xu XH,McFarlin DE

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To use punch skin biopsies to evaluate the loss of intra-epidermal nerve fibers in sensory neuropathies. BACKGROUND:Previous assessments of epidermal nerve fibers have been constrained by relatively insensitive staining techniques and variability in quantification. METHODS:Punch skin biopsies were performed...

journal_title：Neurology

authors： McCarthy BG,Hsieh ST,Stocks A,Hauer P,Macko C,Cornblath DR,Griffin JW,McArthur JC

更新日期：1995-10-01 00:00:00

abstract：:Medical therapy is the mainstay for epilepsy, with most patients well controlled on a single antiepileptic drug (AED). In this non-refractory group, many patients have medication side effects and occasional seizures. Approximately 30% of patients with partial epilepsy and 25% of patients with generalized epilepsy are ...

journal_title：Neurology

authors： Nadkarni S,LaJoie J,Devinsky O

更新日期：2005-06-28 00:00:00