Molecular cloning of rat bone morphogenetic protein (BMP) type IA receptor and its expression during ectopic bone formation induced by BMP.

abstract：:Cholestasis and hepatitis can cause continuous liver damage that may ultimately result in liver fibrosis. In a previous study, we demonstrated that microRNA-29a (miR-29a) protects against liver fibrosis. Toll-like receptor 2 (TLR2) and TLR4 are pattern recognition receptors of bacterial lipoprotein and lipopolysacchar...

journal_title：Biochemical and biophysical research communications

authors： Lin YC,Wang FS,Yang YL,Chuang YT,Huang YH

更新日期：2018-02-12 00:00:00

abstract：:Transgenic (TG) mice expressing porcine GH receptor (pGHR) directed by a 762-bp proximal leptin promoter were used to analyze the capability of the promoter to drive and regulate pGHR expression in vivo. Transgene expression occurred in inguinal, retroperitoneal, and epididymal/parametrial fat depots in both male and ...

journal_title：Biochemical and biophysical research communications

authors： Chen XL,Hartzell DL,McGraw RA,Hausman GJ,Dean RG

更新日期：1999-08-19 00:00:00

abstract：:The potential antiatherogenic actions of the angiotensin II receptor antagonist, losartan were investigated in apolipoprotein (apo) E deficient mice, an animal model with severe hypercholesterolemia and extensive atherosclerosis. In these animals accelerated atherosclerosis is associated with increased lipid peroxidat...

journal_title：Biochemical and biophysical research communications

authors： Keidar S,Attias J,Smith J,Breslow JL,Hayek T

更新日期：1997-07-30 00:00:00

abstract：:Several studies have shown that transplantation of embryonic stem cells into diabetic animals either improved or normalized blood glucose levels. In this study, we examined the dose-dependent effect of early (prediabetic stage) intravenous administration of human umbilical cord blood (HUCB) mononuclear cells on blood ...

journal_title：Biochemical and biophysical research communications

authors： Ende N,Chen R,Reddi AS

更新日期：2004-12-17 00:00:00

abstract：:MicroRNA let-7i is up-regulated in T cells from patients with Ankylosing Spondylitis (AS). In this study, we investigated the role of let-7i in T cells survival. Our results demonstrated down-regulation of insulin-like growth factor-1 receptor (IGF1R) in T cells from patients with AS. Luciferase reporter assay suggest...

journal_title：Biochemical and biophysical research communications

authors： Hou C,Zhu M,Sun M,Lin Y

更新日期：2014-10-31 00:00:00

abstract：:In multiple myeloma (MM), bone marrow microenvironment has an important role for the survival and growth of plasma cells. We previously showed that a high bone turnover, induced by ovariectomy, increased MM cells growth in the 5T2MM model. The present study characterized a new plasma cell line (5THL) which was isolate...

journal_title：Biochemical and biophysical research communications

authors： Libouban H,Moreau MF,Baslé MF,Bataille R,Chappard D

更新日期：2004-04-09 00:00:00

abstract：:The synthetic (1-->6)-alpha-D-glucopyranan with branching and without branching were tested as a new hypoglycaemic drug. (1-->6)-alpha-D-glucopyranan having an alpha-D-glucopyranosyl branch at the C-3 position (1) showed a remarkable hypoglycaemic activity on i.p. injection to mice. The polysaccharide having both alph...

journal_title：Biochemical and biophysical research communications

authors： Hatanaka K,Song SC,Maruyama A,Kobayashi A,Kuzuhara H,Akaike T

更新日期：1992-10-15 00:00:00

abstract：:We have identified two types of homologous DNA pairing activity in mouse cell extracts by a strand-transfer assay. Both activities are separated from each other by anion-exchange chromatography; neither of them needs ATP. One requires magnesium ion and is stimulated by Escherichia coli single-stranded DNA binding prot...

journal_title：Biochemical and biophysical research communications

authors： Mishina Y,Shimokawa T,Kawasaki K,Arai N,Shibata T,Koyama H

更新日期：1992-06-30 00:00:00

abstract：:The DiFi and HT-29 human colorectal cancer cell lines were characterized and compared with respect to binding properties of alpha adrenoceptors present on the cell surface. Both cell lines possessed alpha-1 and alpha-2 adrenoceptors of high affinity; however, DiFi cells were rich in alpha-1 adrenoceptors, whereas HT-2...

journal_title：Biochemical and biophysical research communications

authors： Agrawal DK,Wildrick DM,Boman BM

更新日期：1992-05-29 00:00:00

abstract：:To investigate the identity determinants of E. coli threonine tRNA, various transcripts were prepared by in vitro transcription system with T7 RNA polymerase. Substitutions of the anticodon second letter G35 and the third letter U36 to other nucleotides led to a remarkable decrease of threonine charging activity. Char...

journal_title：Biochemical and biophysical research communications

authors： Hasegawa T,Miyano M,Himeno H,Sano Y,Kimura K,Shimizu M

更新日期：1992-04-15 00:00:00

abstract：:It has been suggested that stress stimuli from the microenvironment maintain a subset of tumor cells with stem-like properties, including drug resistance. Here, we investigate whether Sp1, a stress-responsive factor, regulates stemness gene expression and if its inhibition sensitizes cancer cells to chemotherapy. Hydr...

journal_title：Biochemical and biophysical research communications

authors： Chang KY,Huang CT,Hsu TI,Hsu CC,Liu JJ,Chuang CK,Hung JJ,Chang WC,Tsai KK,Chuang JY

更新日期：2017-11-04 00:00:00

abstract：:The 15-kDa selenoprotein (Sep15) has been implicated in etiology of some types of cancer. Herein, inducible RNAi cell lines were established and cell morphology and motility were analyzed. The majority of Sep15-deficient cells (>95%) formed membrane blebs in a dynamic manner. Blebbing cells transformed cell morphology...

journal_title：Biochemical and biophysical research communications

authors： Bang J,Jang M,Huh JH,Na JW,Shim M,Carlson BA,Tobe R,Tsuji PA,Gladyshev VN,Hatfield DL,Lee BJ

更新日期：2015-01-24 00:00:00

abstract：:N(6)-methyl-2(')-deoxyadenosine (MedAdo) is a nucleoside naturally found in prokaryotic DNA. Interestingly, the N(6)-methylation of adenine in DNA seems to have been counter-selected during the course of evolution since MedAdo has not been detected in mammalian DNA until now. We show here that treatment with MedAdo in...

journal_title：Biochemical and biophysical research communications

authors： Charles MP,Ravanat JL,Adamski D,D'Orazi G,Cadet J,Favier A,Berger F,Wion D

更新日期：2004-02-06 00:00:00

abstract：:Using a subtraction cloning approach we had previously isolated a series of murine cDNA clones representing the genes predominantly expressed in the embryonic brain and down-regulated during development. We now report that one of these cDNA clones encodes a novel type of GTP-binding protein. The predicted protein of 4...

journal_title：Biochemical and biophysical research communications

authors： Sazuka T,Tomooka Y,Ikawa Y,Noda M,Kumar S

更新日期：1992-11-30 00:00:00

abstract：:A biological synthesis of phosphocitrate is described from precursors, citrate and adenosinetriphosphate reacting in the presence of rat liver homogenate. Identity of the newly formed product was examined by enzymatic digestion of reactions mixtures, HPLC chromatography and 1H-NMR spectra. Authenticity of product was ...

journal_title：Biochemical and biophysical research communications

authors： Moro L,Stagni N,Luxich E,Sallis JD,de Bernard B

更新日期：1990-07-16 00:00:00

abstract：:PILRα is an immune inhibitory receptor possessing an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain enabling it to deliver inhibitory signals. Binding of PILRα to its ligand CD99 is involved in immune regulation; however, whether there are other PILRα ligands in addition to CD99 is not...

journal_title：Biochemical and biophysical research communications

authors： Kogure A,Shiratori I,Wang J,Lanier LL,Arase H

更新日期：2011-02-18 00:00:00

abstract：:Diverse inner arm dyneins cooperate with outer arm dyneins to produce ciliary beating. This study demonstrates an expression system for inner arm dyneins in Tetrahymena. The motor domain of inner arm dynein (Dyh8p or Dyh12p) was fused with the tail of outer arm dynein (Dyh3p) and expressed in viable DYH3-knockout (vKO...

journal_title：Biochemical and biophysical research communications

authors： Edamatsu M

更新日期：2020-02-26 00:00:00

abstract：:In Dictyostelium discoideum, a novel type of RNA (dutA RNA), which is untranslatable, cytosolic and 1.3 kb in size, appears specifically after the aggregation stage [Yoshida, H. et al. (1994) Nucleic Acids Res. 22, 41-46]. We here show that the dutA gene is transcribed by RNA polymerase II, based on its alpha-amanitin...

journal_title：Biochemical and biophysical research communications

authors： Kumimoto H,Yoshida H,Okamoto K

更新日期：1995-11-02 00:00:00

abstract：:Caspases are the primary executioners of apoptosis. Although procaspases believe to exist as inactive forms in cells, the detailed regulatory system remains unclear. Here we show that glucocorticoid modulatory element-binding protein 1 (GMEB1) is capable of binding to the prodomain of caspase-2. We found that this mol...

journal_title：Biochemical and biophysical research communications

authors： Tsuruma K,Nakagawa T,Shirakura H,Hayashi N,Uehara T,Nomura Y

更新日期：2004-12-24 00:00:00

abstract：:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) may play important roles during hepatitis B virus (HBV) infection. In this study, we used a recombinant human soluble death receptor 5 (sDR5) to explore its effect in a mouse model of HBV-induced acute hepatitis. By measuring blood transaminase activity a...

journal_title：Biochemical and biophysical research communications

authors： Liu YG,Liu SX,Liang XH,Zhang Q,Gao LF,Han LH,Cao YL,Hou N,Du J,Sun WS

更新日期：2007-01-12 00:00:00

abstract：:Mutations in the WNK1 and WNK4 genes result in an inherited hypertensive disease, pseudohypoaldosteronism type II (PHAII). Recently, the KLHL3 and Cullin3 genes were also identified as responsible genes for PHAII. Although we have reported that WNK4 is a substrate for the KLHL3-Cullin3 E3 ligase complex, it is not cle...

journal_title：Biochemical and biophysical research communications

authors： Takahashi D,Mori T,Wakabayashi M,Mori Y,Susa K,Zeniya M,Sohara E,Rai T,Sasaki S,Uchida S

更新日期：2013-08-02 00:00:00

abstract：:To assess the effect of angiotensin II on ion transport in rat isolated proximal tubules and establish the arachidonic acid cytochrome P450 metabolites' role mediating angiotensin II effect and to analyze whether corticosteroids play a role modulating this effect, we studied the effect of low (10 and 100 pM) and high ...

journal_title：Biochemical and biophysical research communications

authors： Sánchez-Mendoza A,López-Sánchez P,Vázquez-Cruz B,Rios A,Martínez-Ayala S,Escalante B

更新日期：2000-06-07 00:00:00

abstract：:We previously described the identification of the 3'end of an unknown gene CDK7 using differential display which appeared to be up-regulated in diabetic kidneys [R.A. Page, C.A. Morris, J.D. Williams, C.J. von Ruhland, A.N. Malik, Isolation of diabetes-associated kidney genes using differential display, Biochem. Bioph...

journal_title：Biochemical and biophysical research communications

authors： Malik AN,Rossios C,Al-Kafaji G,Shah A,Page RA

更新日期：2007-05-25 00:00:00

abstract：:SND p102 is a rat liver endoplasmic reticulum cholesterol ester hydrolase recently described as a member of a conserved family of transcriptional coactivators that promotes phospholipid secretion into lipoproteins when overexpressed in hepatocytes. In this work, we report first evidence for a mechanism of transcriptio...

journal_title：Biochemical and biophysical research communications

authors： Rodríguez L,Ochoa B,Martínez MJ

更新日期：2007-04-27 00:00:00

abstract：:Calcineurin (CN), a calcium-activated phosphatase, plays a critical role in various biological processes including T cell activation. Cabin1, a calcineurin binding protein 1, has been shown to bind directly to CN using its C-terminal region and inhibit CN activity. However, no increase in CN activity has been found in...

journal_title：Biochemical and biophysical research communications

authors： Jang H,Cho EJ,Youn HD

更新日期：2007-07-20 00:00:00

abstract：:By DNA sequence analysis, we have determined a spectrum of 61 spontaneous mutations occurring in the endogenous tonB gene in the polA1 strain of Escherichia coli. The overall mutation frequency was approximately 2.4-fold higher in the polA1 strain and this was attributable to enhanced rates of deletion and frameshift ...

journal_title：Biochemical and biophysical research communications

authors： Agemizu Y,Uematsu N,Yamamoto K

更新日期：1999-08-11 00:00:00

abstract：:We have investigated the effect of chloroform on the phosphorylation of myelin basic proteins because tumor-promoting agents such as phorbol esters and chloroform are known to enhance the activity of protein kinase C. We report that the presence of chloroform, at a concentration known to enhance protein kinase C activ...

journal_title：Biochemical and biophysical research communications

authors： Ulmer JB,Braun PE

更新日期：1987-08-14 00:00:00

abstract：:The uptake of a photolabile taurocholate derivative, (7,7-azo-3 alpha, 12 alpha-dihydroxy-5 beta-cholan-24-oyl)-2-aminoethanesulfonate, 7,7-azo-TC, into rat renal brush-border membrane vesicles was stimulated by Na+ and inhibited by taurocholate indicating an interaction with the Na+/bile salt cotransport system. Irra...

journal_title：Biochemical and biophysical research communications

authors： Burckhardt G,Kramer W,Kurz G,Wilson FA

更新日期：1987-03-30 00:00:00

abstract：:We investigated the effect of ziprasidone, a widely used treatment for schizophrenia, on voltage-dependent K+ (Kv) channels of coronary arterial smooth muscle cells using the patch-clamp technique. Ziprasidone dose-dependently inhibited Kv channels with an IC50 value of 0.39 ± 0.06 μM and a Hill coefficient of 0.62 ± ...

journal_title：Biochemical and biophysical research communications

authors： An JR,Seo MS,Jung HS,Heo R,Kang M,Ha KS,Park H,Park WS

更新日期：2020-08-20 00:00:00

abstract：:To study the effect of interleukin-6 (IL-6) on glucose transport, 2-deoxy-D-glucose (2-DOG) uptake in 3T3-L1 adipocytes after incubation with IL-6 was measured. IL-6 increased 2-DOG uptake maximally after 5 hours by 30 +/- 12%, with a half-maximal effect at an IL-6 concentration of approximately 800 U/mL. 3-O-methylgl...

journal_title：Biochemical and biophysical research communications

authors： Stouthard JM,Oude Elferink RP,Sauerwein HP

更新日期：1996-03-18 00:00:00