CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.

Abstract:

:CXC chemokines have been found to be important in the regulation of angiogenesis and tumor-related immunity, and in promoting organ-specific metastases. This review highlights the importance of CXC chemokine ligands and receptors in mediating non-small cell lung cancer tumor-associated angiogenesis, "immunoangiostasis," and organ-specific metastases. These findings may ultimately lead to clinical strategies to target CXC chemokines in non-small cell lung cancer.

journal_name

Ann N Y Acad Sci

authors

Strieter RM,Belperio JA,Burdick MD,Sharma S,Dubinett SM,Keane MP

doi

10.1196/annals.1322.041

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

351-60

eissn

0077-8923

issn

1749-6632

pii

1028/1/351

journal_volume

1028

pub_type

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