Non-linear microscale alterations in membrane transport by electropermeabilization.

Abstract:

:The purpose of this study was to quantify the changes in cell membrane conductance in response to electropermeabilization, which may elucidate the mechanisms of tissue injury resulting from high-voltage electrical shock. A high-speed, space-clamp and voltage-clamp experimental configuration was used. The pulse parameters of an imposed transmembrane potential that are instrumental in membrane properties alteration were precisely controlled. The dynamics of the non-linear electroporation response was characterized.

journal_name

Ann N Y Acad Sci

authors

Gowrishankar TR,Chen W,Lee RC

doi

10.1111/j.1749-6632.1998.tb10154.x

subject

Has Abstract

pub_date

1998-09-11 00:00:00

pages

205-16

eissn

0077-8923

issn

1749-6632

journal_volume

858

pub_type

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