Epigenetics in lupus.

abstract：:The presence of R. prowazekii in lice using R. prowazekii-specific qPCR cassettes showed the changes of the rickettsial burden in the lice post-infection. ...

journal_title：Annals of the New York Academy of Sciences

authors： Rozmajzl PJ,Houhamdi L,Jiang J,Raoult D,Richards AL

更新日期：2006-10-01 00:00:00

abstract：:About 1 of 10 women, particularly those older than 60 years of age, shows some degree of thyroid hormone deficiency. Thyroid diseases are generally characterized by perturbations of thyroid signaling homeostasis. The most common examples of thyroid diseases include hypothyroidism, hyperthyroidism, and several types of...

journal_title：Annals of the New York Academy of Sciences

authors： Pistollato F,Masias M,Agudo P,Giampieri F,Battino M

更新日期：2019-05-01 00:00:00

abstract：:The finding of an association between the epsilon 4 allele of the APOE locus and the early expression of late-onset Alzheimer's disease (AD) is robust. However, the estimates of the proportion of AD cases carrying one or more copies of the epsilon 4 allele vary dramatically between studies (highest estimates being 180...

journal_title：Annals of the New York Academy of Sciences

authors： Mullan M,Scibelli P,Duara R,Fallin D,Gold M,Schinka J,Hoyne J,Osborne A,Sevush S,Crawford F

更新日期：1996-12-16 00:00:00

abstract：:Clinicians use the combination of Tanner stage 5 (T5) of puberty, final height, and epiphyseal fusion to define maturity. We tested the hypothesis that changes in body composition related to age are identifiable during T5. Asian, Black, Hispanic, and White T5 adolescents (n = 148, 72 females) had measurements taken of...

journal_title：Annals of the New York Academy of Sciences

authors： Horlick M,Thornton J,Wang J,Levine LS,Fedun B,Pierson RN Jr

更新日期：2000-05-01 00:00:00

abstract：:Uncertainty in exposure assessment and uncertainty in kinetic models of early effects after exposure to a toxin are addressed in this paper. Sources of uncertainty in the determination of exposure of workers in chemical industry exposed to dioxins are exhibited and a simple kinetic model for biomonitor measurements of...

journal_title：Annals of the New York Academy of Sciences

authors： Edler L

更新日期：1999-01-01 00:00:00

abstract：:Pheochromocytomas (PCCs) are neuroendocrine tumors of chromaffin tissue that produce catecholamines. They are usually located in the adrenal medulla, although in about 10% the tumors arise from extra-adrenal chromaffin tissue. The majority of PCCs arise sporadically, but PCCs occur also in the context of hereditary ca...

journal_title：Annals of the New York Academy of Sciences

authors： Korpershoek E,Van Nederveen FH,Dannenberg H,Petri BJ,Komminoth P,Perren A,Lenders JW,Verhofstad AA,De Herder WW,De Krijger RR,Dinjens WN

更新日期：2006-08-01 00:00:00

abstract：:The computation of ITD begins with preservation of the phase angle of spectral components by eighth-nerve fibers and by cells of the nucleus magnocellularis. At the level of the nucleus laminaris, the difference in phase angle of corresponding spectral components in the left and right ears is extracted. At the next le...

journal_title：Annals of the New York Academy of Sciences

authors： Takahashi TT

更新日期：1989-01-01 00:00:00

abstract：:Pregnancy rates among adolescents have not decreased over the last 10 years, despite numerous efforts. To solve this important health problem, the major strategy recommended is to encourage contraceptive use among sexually active teenagers. An important means of obtaining this is by promoting methods that are not depe...

journal_title：Annals of the New York Academy of Sciences

authors： Wildemeersch D,Van Kets H,Vrijens M,Delbarge W,Van Trappen Y,Temmerman M,Depypere H,Thiery M

更新日期：1997-06-17 00:00:00

abstract：:Approximately 40 to 50 infants and children with similar epidemiologic, clinical, and laboratory features of AIDS have been described. The occurrence of significant numbers of patients with PAIDS in geographic areas that are associated with similar risk factors and clinical features of AIDS suggests a common cause. Im...

journal_title：Annals of the New York Academy of Sciences

authors： Ammann AJ,Wara DW,Cowan MJ

更新日期：1984-01-01 00:00:00

abstract：:Cardiac development is characterized by a complex interplay of chemical, mechanical, and electrical forces, which together contribute to the proper formation of the heart muscle. In adult myocardium, cardiomyocytes are elongated, well-coupled by gap junctions, and organized in spatially well-defined muscle fibers. Thi...

journal_title：Annals of the New York Academy of Sciences

authors： Pijnappels DA,Gregoire S,Wu SM

更新日期：2010-02-01 00:00:00

abstract：:Tick burdens cause direct damage to hosts and transmit several disease agents, the majority of which are secreted into feeding lesions through tick salivary glands. Reduced incidence of naturally transmitted tick-borne diseases was recently observed among cattle immunized with tick salivary gland extracts (TSGE). The ...

journal_title：Annals of the New York Academy of Sciences

authors： Jittapalapong S,Phichitrasilp T,Chanphao H,Rerkamnuychoke W,Stich RW

更新日期：2008-12-01 00:00:00

abstract：:The human ABO(H) blood group phenotypes arise from the evolutionarily oldest genetic system found in primate populations. While the blood group antigen A is considered the ancestral primordial structure, under the selective pressure of life-threatening diseases blood group O(H) came to dominate as the most frequently ...

journal_title：Annals of the New York Academy of Sciences

authors： Arend P

更新日期：2018-08-01 00:00:00

abstract：:Epidermal growth factor receptor (EGF-R) has been implicated in the growth of endometrial cancer. In the present study, immunostaining of EGF-R was investigated in different endometrial cancer histotypes. For this purpose 34 surgical samples of primary endometrial carcinoma were studied using monoclonal anti-EGF-R ant...

journal_title：Annals of the New York Academy of Sciences

authors： Jasonni VM,Santini D,Amadori A,Ceccarelli C,Naldi S

更新日期：1994-09-30 00:00:00

abstract：:During food shortage, organisms activate defense mechanisms to maximize their chance of survival. At least in part, these responses are triggered by changes in hormonal status and neural status during starvation. The hypothalamus is organized as a collection of distinct autonomously active nuclei and is considered to ...

journal_title：Annals of the New York Academy of Sciences

authors： Chiba T,Fujita S,Kubota H,Inoue D,Mizuno A,Komatsu T,Yamaza H,Higami Y,Shimokawa I

更新日期：2007-11-01 00:00:00

abstract：:The molecular genetic basis of adaptive change in phenotype is a major outstanding issue in evolutionary biology. Evolutionary change in coat and plumage color is a promising system for making progress in this field. Most notably, recent work on the molecular genetic basis of hair and feather color has identified seve...

journal_title：Annals of the New York Academy of Sciences

authors： Mundy NI,Kelly J,Theron E,Hawkins K

更新日期：2003-06-01 00:00:00

abstract：:Environments are changing rapidly, and to cope with these changes, organisms have to adapt. Adaptation can take many shapes and occur at different speeds, depending on the type of response, the trait, the population, and the environmental conditions. The biodiversity crisis that we are currently facing illustrates tha...

journal_title：Annals of the New York Academy of Sciences

authors： Kristensen TN,Ketola T,Kronholm I

更新日期：2020-09-01 00:00:00

abstract：:Mounting evidence suggests that oxidative processes contribute to the pathogenesis of atherosclerosis and that antioxidants may represent a strategy to complement the lowering of lipids in the therapy of this disease. Although multiple molecular events have been identified in vitro and although it is tempting to ascri...

journal_title：Annals of the New York Academy of Sciences

authors： Sigal E,Laughton CW,Mulkins MA

更新日期：1994-04-18 00:00:00

abstract：:Calcium-dependent activator protein for secretion (CAPS) was initially identified in brain cytosol based on its ability to reconstitute calcium-triggered dense-core vesicle (DCV) exocytosis in permeable cell lines (PC12) of adrenal chromaffin origin. Current evidence indicates that CAPS functions selectively in DCV ex...

journal_title：Annals of the New York Academy of Sciences

authors： Wassenberg JJ,Martin TF

更新日期：2002-10-01 00:00:00

abstract：:Henry Kandrup wrote prolifically on the problem of relaxation of stellar systems. His picture of relaxation was significantly more refined than the standard description in terms of phase mixing and violent relaxation. In this article, I summarize Henry's work in this and related areas. ...

journal_title：Annals of the New York Academy of Sciences

authors： Merritt D

更新日期：2005-06-01 00:00:00

abstract：:The objective of this article is to investigate the influence of endothelin-1 (ET-1) on human monocyte Na(+)/H(+) exchanger (NHE) activity and on the atherosclerosis-related monocyte functions. ET-1 caused an increase in pHi and in (22)Na influx of monocytes. A reversal of ET-1 effect on pHi was observed in the presen...

journal_title：Annals of the New York Academy of Sciences

authors： Koliakos G,Befani C,Paletas K,Kaloyianni M

更新日期：2007-01-01 00:00:00

abstract：:Within the past few years, developmental scientists have switched their attention from the study of DNA sequencing to the epigenetic state of the genome. Studying epigenetics could present the key to understanding gene expression changes without altering the basic structure of DNA. For example, the blastocyst, trophec...

journal_title：Annals of the New York Academy of Sciences

authors： Palini S,De Stefani S,Scala V,Dusi L,Bulletti C

更新日期：2011-03-01 00:00:00

abstract：:Infertility is defined as the inability of a couple to conceive despite trying for a year, and it affects approximately 15% of the reproductive-age population. It is considered a genetically lethal factor, as the family lineage stops at that individual with no progeny produced. A genetic defect associated with an infe...

journal_title：Annals of the New York Academy of Sciences

authors： Hwang K,Yatsenko AN,Jorgez CJ,Mukherjee S,Nalam RL,Matzuk MM,Lamb DJ

更新日期：2010-12-01 00:00:00

abstract：:Molecular genetics teaches three lessons relevant to the nature of genetic change during evolution: (1) Genomes are organized as hierarchies of composite systems (multidomain protein-coding sequences; functional loci made up of regulatory, coding, processing, and intervening sequences; and multilocus regulons and repl...

journal_title：Annals of the New York Academy of Sciences

authors： Shapiro JA

更新日期：1999-05-18 00:00:00

abstract：:Several years of survey data indicate that illicit drug use among U.S. youth was at its highest level in 1979. Generally, the use of some illicit drugs declined progressively throughout the 1980s, stabilized, and then decreased slightly. Reducing illicit drug use among U.S. youth continues to be a priority of federal,...

journal_title：Annals of the New York Academy of Sciences

authors： Banken JA

更新日期：2004-10-01 00:00:00

abstract：:The following on molecular mechanisms of Barrett's esophagus and adenocarcinoma contains commentaries on the mechanism of bile and gastric acid induced damage; the roles of BMP-4 and CDX-2 in the development of intestinal metaplasia; the transcription factors driving intestinalization in Barrett's esophagus; the contr...

journal_title：Annals of the New York Academy of Sciences

authors： Dvorak K,Goldman A,Kong J,Lynch JP,Hutchinson L,Houghton JM,Chen H,Chen X,Krishnadath KK,Westra WM

更新日期：2011-09-01 00:00:00

abstract：:Recent perceptual experiments with normal adult listeners show that phonetic information can readily be conveyed by sinewave replicas of speech signals. These tonal patterns are made of three sinusoids set equal in frequency and amplitude to the respective peaks of the first three formants of natural-speech utterances...

journal_title：Annals of the New York Academy of Sciences

authors： Remez RE,Rubin PE,Pisoni DB

更新日期：1983-01-01 00:00:00

abstract：:The same retinal image motion can be produced by a variety of combinations of eye and target motion. In natural conditions, extraretinal information disambiguates retinal information for motion perception. By controlling the timing of visual motion with respect to saccades, it was possible to appraise the roles for mo...

journal_title：Annals of the New York Academy of Sciences

authors： Lee C,Lee J

更新日期：2005-04-01 00:00:00

abstract：:Lipogenesis occurs primarily in the liver, where dietary carbohydrates control the expression of key enzymes in glycolytic and lipogenic pathways. We have recently discovered that the transcription factor XBP1, best known as a key regulator of the unfolded protein response (UPR), is required for de novo fatty acid syn...

journal_title：Annals of the New York Academy of Sciences

authors： Glimcher LH,Lee AH

更新日期：2009-09-01 00:00:00

abstract：:This study investigates the effects of agmatine on naloxone-precipitated withdrawal syndrome in morphine-dependent guinea pig ileum. Male guinea pigs that were starved for 24 hours were decapitated after cervical dislocation, and terminal portions of the ilea were removed. Segments were fixed at a resting tension of 1...

journal_title：Annals of the New York Academy of Sciences

authors： Aricioglu F,Ercil E,Dulger G

更新日期：2003-12-01 00:00:00

abstract：:Epithelial cell sheet formation is central to many aspects of vertebrate development and function. For example, it is a major principle of differentiation in embryogenesis and regeneration, enables the compartmentalization of tissues, and is the basis for the maintenance of homeostasis throughout the body. A key chara...

journal_title：Annals of the New York Academy of Sciences

authors： Yano T,Kanoh H,Tamura A,Tsukita S

更新日期：2017-10-01 00:00:00