Molecular mechanisms of Barrett's esophagus and adenocarcinoma.

Abstract:

:The following on molecular mechanisms of Barrett's esophagus and adenocarcinoma contains commentaries on the mechanism of bile and gastric acid induced damage; the roles of BMP-4 and CDX-2 in the development of intestinal metaplasia; the transcription factors driving intestinalization in Barrett's esophagus; the contribution of bone marrow to metaplasia and adenocarcinoma; activation and inactivation of transcription factors; and a novel study design targeting molecular pathways in Barrett's esophagus.

journal_name

Ann N Y Acad Sci

authors

Dvorak K,Goldman A,Kong J,Lynch JP,Hutchinson L,Houghton JM,Chen H,Chen X,Krishnadath KK,Westra WM

doi

10.1111/j.1749-6632.2011.06062.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

381-91

eissn

0077-8923

issn

1749-6632

journal_volume

1232

pub_type

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