Construction of an auditory space map.

Abstract:

:The computation of ITD begins with preservation of the phase angle of spectral components by eighth-nerve fibers and by cells of the nucleus magnocellularis. At the level of the nucleus laminaris, the difference in phase angle of corresponding spectral components in the left and right ears is extracted. At the next level, the central nucleus, neurons are consolidated into tonotopic ensembles in which preferred delta phi and frequency covary, so that only a single ITD coactivates all constituent neurons. Neurons of such ensembles project convergently on space-specific neurons, endowing the space-specific neuron with a selectivity for ITD and, therefore, a selectivity for azimuth. Ensembles representing ITDs corresponding to ipsilateral and contralateral auditory hemi-fields are found in the core and lateral shell of the central nucleus, respectively. The lateral shell receives its representation of the contralateral hemi-field from the opposite central nucleus core. The central nucleus core is innervated by the contralateral nucleus laminaris, which contains a representation of contralateral space. The projection from the lateral shell to the ipsilateral external nucleus forms a map of contralateral space in the external nucleus.

journal_name

Ann N Y Acad Sci

authors

Takahashi TT

doi

10.1111/j.1749-6632.1989.tb42193.x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

101-13

eissn

0077-8923

issn

1749-6632

journal_volume

563

pub_type

杂志文章
  • Orbital versus dorsolateral prefrontal cortex: anatomical insights into content versus process differentiation models of the prefrontal cortex.

    abstract::Content differentiation models posit that different areas of the prefrontal cortex perform similar operations but differ in terms of the content that is operated on. For example, it has been suggested that the orbitofrontal cortex (OFC) and the dorsolateral prefrontal cortex (DLPFC) perform similar working memory or i...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1401.012

    authors: Zald DH

    更新日期:2007-12-01 00:00:00

  • SPR imaging-based salivary diagnostics system for the detection of small molecule analytes.

    abstract::Saliva is an underused fluid with considerable promise for biomedical testing. Its potential is particularly great for monitoring small-molecule analytes since these are often present in saliva at concentrations that correlate well with their free levels in blood. We describe the development of a prototype diagnostic ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1384.026

    authors: Fu E,Chinowsky T,Nelson K,Johnston K,Edwards T,Helton K,Grow M,Miller JW,Yager P

    更新日期:2007-03-01 00:00:00

  • Cardiomyopathy and encephalopathy in AIDS.

    abstract::HIV encephalopathy has been in the past years the most typical CNS disorder in patients with AIDS. Histologic abnormalities consist in astrocytosis, myelin pallor, infiltration by infected macrophages, resident microglia and multinucleated giant cells, generally in absence of direct infection of neurons. Mononuclear p...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2001.tb03907.x

    authors: Antinori A,Giancola ML,Alba L,Soldani F,Grisetti S

    更新日期:2001-11-01 00:00:00

  • The viral eukaryogenesis hypothesis: a key role for viruses in the emergence of eukaryotes from a prokaryotic world environment.

    abstract::Understanding how the gulf between prokaryotic and eukaryotic cellular design arose is a major challenge. The viral eukaryogenesis (VE) hypothesis addresses the challenge of eukaryotic origins by suggesting the first eukaryotic cell was a multimember consortium consisting of a viral ancestor of the nucleus, an archaea...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.04994.x

    authors: Bell PJ

    更新日期:2009-10-01 00:00:00

  • LHRH and sexual dimorphism.

    abstract::An increasing amount of evidences suggests that galanin plays an important role in the regulation of reproduction in the rat. Galanin is colocalized with luteinizing hormone-releasing hormone (LHRH) in a subset of LHRH neurons, and the pattern of coexpression is sexually dimorphic, with a higher incidence of colocaliz...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1998.tb10694.x

    authors: Merchenthaler I

    更新日期:1998-12-21 00:00:00

  • The role of input-output analysis of energy and ecologic systems. In the early development of ecological economics--a personal perspective.

    abstract::A summary is provided of the early history of research on the flow of nonrenewable energy resources through the economy and of the flow of renewable energy resources through a natural ecosystem. The techniques are similar, and many specific applications are provided. A combined economic and ecological technique is als...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.05165.x

    authors: Hannon B

    更新日期:2010-01-01 00:00:00

  • Evolutionary genetics of the melanocortin-1 receptor in vertebrates.

    abstract::The molecular genetic basis of adaptive change in phenotype is a major outstanding issue in evolutionary biology. Evolutionary change in coat and plumage color is a promising system for making progress in this field. Most notably, recent work on the molecular genetic basis of hair and feather color has identified seve...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2003.tb03194.x

    authors: Mundy NI,Kelly J,Theron E,Hawkins K

    更新日期:2003-06-01 00:00:00

  • Cross-linking of T-cell receptors is insufficient to induce IL-2 responsiveness (activation) in resting Lyt-2+ T cells. IL-4 or RIF are essential as second signal.

    abstract::High-density (resting) murine Lyt-2+ T cells exposed in vitro to the ligand concanavalin A (Con A), or immobilized F23.1 monoclonal antibody (mAb) recognizing an allotypic determinant on the T-cell receptor (TCR), or high-density (resting) allogeneic B stimulator cells remain IL-2-unresponsive; such cells do not expre...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1988.tb36332.x

    authors: Wagner H,Heeg K,Hardt C

    更新日期:1988-01-01 00:00:00

  • Contextual inhibitory gating of impulse traffic in the intra-amygdaloid network.

    abstract::New data on the organization of the intra-amygdaloid circuit is reviewed, beginning with the basolateral (BL) complex, the main input station of the amygdala for sensory afferents, and concluding with the central (CE) nucleus, an important source of projections to brain-stem structures mediating fear responses. The BL...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2003.tb07073.x

    authors: Paré D,Royer S,Smith Y,Lang EJ

    更新日期:2003-04-01 00:00:00

  • Antigenic profile, prevalence, and clinical significance of antiphospholipid antibodies in women referred for in vitro fertilization.

    abstract::The aim of this prospective study was to assess the prevalence of antiphospholipid antibodies (aPL) in women who had undergone in vitro fertilization (IVF) and the relationship between aPL and IVF outcome. A total of 101 infertile women with at least three unsuccessful IVF attempts were consecutively included in this ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1422.048

    authors: Sanmarco M,Bardin N,Camoin L,Beziane A,Dignat-George F,Gamerre M,Porcu G

    更新日期:2007-06-01 00:00:00

  • Phase-amplitude coupling between theta and gamma oscillations adapts to speech rate.

    abstract::Low- and high-frequency cortical oscillations play an important role in speech processing. Low-frequency neural oscillations in the delta (<4 Hz) and theta (4-8 Hz) bands entrain to the prosodic and syllabic rates of speech, respectively. Theta band neural oscillations modulate high-frequency neural oscillations in th...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/nyas.14099

    authors: Lizarazu M,Lallier M,Molinaro N

    更新日期:2019-10-01 00:00:00

  • Design and synthetic considerations of matrix metalloproteinase inhibitors.

    abstract::Experimental evidence confirms that the matrix metalloproteinases (MMPs) play a fundamental role in a wide variety of pathologic conditions that involve connective tissue destruction including osteoarthritis and rheumatoid arthritis, tumor metastasis and angiogenesis, corneal ulceration, multiple sclerosis, periodonta...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1999.tb07674.x

    authors: Skotnicki JS,Zask A,Nelson FC,Albright JD,Levin JI

    更新日期:1999-06-30 00:00:00

  • Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits.

    abstract::Alexithymia has been associated with both posttraumatic stress disorder and neuroendocrine responses to stress. This study examined the relationship of alexithymia to salivary cortisol and 3-methoxy-4-hydroxy-phenylglycol (MHPG) in a sample of police academy recruits exposed to a video stress challenge. Alexithymia sc...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1364.034

    authors: McCaslin SE,Inslicht SS,Neylan TC,Metzler TJ,Otte C,Lenoci M,Henn-Haase C,Best S,Yehuda R,Marmar CR

    更新日期:2006-07-01 00:00:00

  • Analysis of foreign protein overproduction in recombinant CHO cells. Effect of growth kinetics and cell cycle traverse.

    abstract::Intracellular foreign protein (beta-galactosidase) expression in recombinant CHO cell lines in continuous culture was analyzed by developing a mathematical model that includes the effects of metabolic burden and cell cycle dependence of intracellular foreign protein expression. This combined growth kinetic and cell cy...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1994.tb47392.x

    authors: Gu MB,Todd P,Kompala DS

    更新日期:1994-05-02 00:00:00

  • Mouse 5-HT2B receptor-mediated serotonin trophic functions.

    abstract::5-HT2B receptors, in addition to phospholipase C stimulation, are able to trigger activation of the proto-oncogene product p21ras. During mouse embryogenesis, a peak of 5-HT2B receptor expression is detected at the neurulation stage; we localized the 5-HT2B expression in neural crest cells, heart myocardium, and somit...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1998.tb10174.x

    authors: Choi DS,Kellermann O,Richard S,Colas JF,Bolaños-Jimenez F,Tournois C,Launay JM,Maroteaux L

    更新日期:1998-12-15 00:00:00

  • Insulin regulation of gluconeogenesis.

    abstract::The coordinated regulation between cellular glucose uptake and endogenous glucose production is indispensable for the maintenance of constant blood glucose concentrations. The liver contributes significantly to this process by altering the levels of hepatic glucose release, through controlling the processes of de novo...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/nyas.13435

    authors: Hatting M,Tavares CDJ,Sharabi K,Rines AK,Puigserver P

    更新日期:2018-01-01 00:00:00

  • Oxidative stress and energy crises in neuronal dysfunction.

    abstract::Mitochondrial dysfunction is implicated in many forms of cell death, particularly in the central nervous system. The mitochondria are required at the same time to generate adenosine 5'-triphosphate (ATP) for the cell, sequester excess cytoplasmic Ca(2+), and both produce and detoxify superoxide free radicals. The elec...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1427.002

    authors: Nicholls DG

    更新日期:2008-12-01 00:00:00

  • Total body dual X-ray absorptiometry is a good measure of both fat mass and fat-free mass in liver cirrhosis compared to "gold-standard" techniques. Melbourne Liver Group.

    abstract::Liver cirrhosis is a condition in which overnutrition, edema, and undernutrition can coexist simultaneously, or successively, over a period of time, giving rise to alterations in body composition, as well as systemic and multiorgan manifestations. We undertook a cross-sectional study of body composition in 198 adult p...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2000.tb06421.x

    authors: Strauss BJ,Gibson PR,Stroud DB,Borovnicar DJ,Xiong DW,Keogh J

    更新日期:2000-05-01 00:00:00

  • Influence of aging and enriched environment on motor activity and emotional responses in mice.

    abstract::We have evaluated different behavioral parameters in ICR (CD1) female mice of three different ages (38-39 weeks: mature; 62 weeks: late mature; 90 weeks: old), and addressed the effects of an enriched housing condition. We employed the following battery of tests: Holeboard, open field, elevated plus-maze (EPM), and fo...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1395.060

    authors: Zambrana C,Marco EM,Arranz L,de Castro NM,Viveros MP,de la Fuente M

    更新日期:2007-04-01 00:00:00

  • Cyclic nucleotide-gated channels. Molecular mechanisms of activation.

    abstract::Activation of cyclic nucleotide-gated (CNG) channels represents the final step in the transduction pathways in both vision and olfaction. Over the past several years, CNG channels have been found in a variety of other cell types where they might fulfill various physiological functions. The olfactory and photoreceptor ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1999.tb11352.x

    authors: Broillet MC,Firestein S

    更新日期:1999-04-30 00:00:00

  • Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids.

    abstract::Tocopherols and tocotrienols (vitamin E) and ascorbic acid (vitamin C) as well as the carotenoids react with free radicals, notably peroxyl radicals, and with singlet molecular oxygen (1O2), this being the basis of their function as antioxidants. RRR-alpha-tocopherol is the major peroxyl radical scavenger in biologica...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1992.tb17085.x

    authors: Sies H,Stahl W,Sundquist AR

    更新日期:1992-09-30 00:00:00

  • Human experience with canalith repositioning maneuvers.

    abstract::Three distinct pathological conditions, related to different means by which dense intralabyrinthine particles interfere with the function of a semicircular canal and cause nystagmus and vertigo, are amenable to treatment with repositioning maneuvers. Known as benign paroxysmal positional vertigo and variants, these co...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2001.tb03744.x

    authors: Epley JM

    更新日期:2001-10-01 00:00:00

  • Dielectric properties of skeletal muscle during ischemia in the frequency range from 50 Hz to 200 MHz.

    abstract::The complex dielectric properties of canine skeletal muscles were measured at 25 degrees C during ischemia in the frequency range from 50 Hz to 200 MHz. The dielectric spectrum of skeletal muscle shows an alpha-dispersion below 1 kHz and a beta-dispersion with a relaxation frequency of about 100 kHz. The alpha-dispers...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1999.tb09449.x

    authors: Schäfer M,Kirlum HJ,Schlegel C,Gebhard MM

    更新日期:1999-04-20 00:00:00

  • Development of the eye after gestational exposure to cocaine. Vascular disruption in the retina of rats and humans.

    abstract::Clinical and basic research in the area of drugs of abuse are of utmost importance since they provide the necessary background for health programs in one of the main problems of contemporary society. The available data in this field demonstrate that acute, subacute and/or chronic abuse of illicit drugs, e.g., cocaine,...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1996.tb17448.x

    authors: Silva-Araújo A,Tavares MA

    更新日期:1996-10-31 00:00:00

  • Coagulation and splenectomy: an overview.

    abstract::Venous thromboembolic events, such as pulmonary embolism, deep venous thrombosis, and portal vein thrombosis, have been observed in adult thalassemia patients, mainly in beta-thalassemia intermedia. The clinical findings are consistent with the observation of several alterations that indicate a state of activation of ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1345.039

    authors: Cappellini MD,Grespi E,Cassinerio E,Bignamini D,Fiorelli G

    更新日期:2005-01-01 00:00:00

  • Memory for tonal pitches: a music-length effect hypothesis.

    abstract::One of the most studied effects of verbal working memory (WM) is the influence of the length of the words that compose the list to be remembered. This work aims to investigate the nature of musical WM by replicating the word length effect in the musical domain. Length and rate of presentation were manipulated in a rec...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.04787.x

    authors: Akiva-Kabiri L,Vecchi T,Granot R,Basso D,Schön D

    更新日期:2009-07-01 00:00:00

  • What effect does controlling platelets have on atherosclerosis?

    abstract::Platelets play important roles for hemostasis with activated platelets adhering to the injured vessel wall to initiate platelet aggregation. At the same time, our study revealed the cytotoxic effect on endothelial cells characterized by an increase of intracellular Ca++ and a decrease of EDRF production, which may cau...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1994.tb17334.x

    authors: Numano F,Kishi Y,Ashikaga T,Hata A,Makita T,Watanabe R

    更新日期:1995-01-17 00:00:00

  • Differential phosphorylation of occludin and tricellulin by CK2 and CK1.

    abstract::In epithelial and endothelial cell layers tight junctions form selective apicolateral paracellular barriers separating luminal and extracellular spaces from the underlying tissues. Within the tight junctions the tetraspan transmembrane proteins occludin, claudins, and tricellulin form anastomosing strands of protein c...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.04043.x

    authors: Dörfel MJ,Westphal JK,Huber O

    更新日期:2009-05-01 00:00:00

  • A role for the CISD2 gene in lifespan control and human disease.

    abstract::CISD2, the causative gene for Wolfram syndrome 2 (WFS2), is an evolutionarily conserved novel gene. Recently, we have demonstrated that CISD2 is involved in mammalian lifespan control; this work also establishes WFS2 as a mitochondria-mediated disorder and effectively links CISD2 gene function, mitochondrial integrity...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2010.05619.x

    authors: Chen YF,Wu CY,Kirby R,Kao CH,Tsai TF

    更新日期:2010-07-01 00:00:00

  • A fusion protein composed of IL-2 and caspase-3 ameliorates the outcome of experimental inflammatory colitis.

    abstract::Targeted depletion of immune cells expressing the interleukin-2 (IL-2) receptor can exacerbate inflammatory bowel disease (IBD) through elimination of regulatory T (Treg) cells, or ameliorate its course by depletion of cytotoxic cells. To answer this question we used a fusion protein composed of IL-2 and caspase-3 (IL...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.04877.x

    authors: Sagiv Y,Kaminitz A,Lorberboum-Galski H,Askenasy N,Yarkoni S

    更新日期:2009-09-01 00:00:00