Immortal ethics.

abstract：:Phosphomannose isomerase (PMI), an enzyme not present in many plants, catalyzes the reversible interconversion of mannose 6-phosphate and fructose 6-phosphate. Plant cells lacking this enzyme are incapable of surviving on synthetic medium containing mannose. Thus PMI/mannose selection has utility in the identification...

journal_title：Annals of the New York Academy of Sciences

authors： Privalle LS

更新日期：2002-05-01 00:00:00

abstract：:It is well known that hemodynamic load is one of the most important determinants of cardiac structure and function. Circadian variations in blood pressure (BP) values are usually accompanied by consensual changes in peripheral resistance and/or cardiac output. In recent years, in hypertensive patients with left ventri...

journal_title：Annals of the New York Academy of Sciences

authors： Rizzoni D,Agabiti-Rosei E

更新日期：1996-08-15 00:00:00

abstract：:In the history of science, technical advances often precede periods of rapid accumulation of knowledge. Within the past three decades, discoveries that enabled the noninvasive measurement of the psychobiology of stress (in saliva) have added new dimensions to the study of health and human development. This widespread ...

journal_title：Annals of the New York Academy of Sciences

authors： Granger DA,Kivlighan KT,el-Sheikh M,Gordis EB,Stroud LR

更新日期：2007-03-01 00:00:00

abstract：:Acetaldehyde covalently binds to purified tubulin in vitro to form both stable and unstable adducts. The formation of stable adducts can be greatly facilitated by the inclusion of the relatively gentle and Schiff base specific reducing agent, sodium cyanoborohydride. Although the tubulin molecule has multiple lysine r...

journal_title：Annals of the New York Academy of Sciences

authors： Tuma DJ,Jennett RB,Sorrell MF

更新日期：1987-01-01 00:00:00

abstract：:The effects of TCDD exposure on the developing immune system were investigated in Wistar/Fischer hybrid or Fischer rats. Fetal and neonatal rats were exposed to TCDD through maternal dosing (5 muk/kg) on day 18 of gestation and on days 0, 7, and 14 of postnatal life (group 1). Another group of neonatal rats was expose...

journal_title：Annals of the New York Academy of Sciences

authors： Luster MI,Faith RE,Clark G

更新日期：1979-05-31 00:00:00

abstract：:The coordinated regulation between cellular glucose uptake and endogenous glucose production is indispensable for the maintenance of constant blood glucose concentrations. The liver contributes significantly to this process by altering the levels of hepatic glucose release, through controlling the processes of de novo...

journal_title：Annals of the New York Academy of Sciences

authors： Hatting M,Tavares CDJ,Sharabi K,Rines AK,Puigserver P

更新日期：2018-01-01 00:00:00

abstract：:Solid evidence has established the negative impact of high iron burden and related tissue damage on the outcome of hemopoietic stem cell transplantation for thalassemia major. Recent improvements in our knowledge of iron metabolism have been focused on elevated non-transferrin-bound iron and labile plasma iron levels ...

journal_title：Annals of the New York Academy of Sciences

authors： Angelucci E,Pilo F

更新日期：2016-03-01 00:00:00

abstract：:An EEG profile for cannabis preparations equated for delta 9-THC activity has been defined in occasional cannabis users in New York and in long-term, high-dose hashish users in Athens. The EEG effects of enhanced alpha activity, decreased beta activity, and decreased mean frequency are dose dependent, both in intensit...

journal_title：Annals of the New York Academy of Sciences

authors： Fink M

更新日期：1976-01-01 00:00:00

abstract：:Neocortex is an important part of the mammalian brain that is quite different from its homologue of the dorsal cortex in the reptilian brain. Whereas dorsal cortex is small, thin, and composed of a single layer of neurons, neocortex is thick and has six layers, while being variable across species in size, number of fu...

journal_title：Annals of the New York Academy of Sciences

authors： Kaas JH

更新日期：2011-04-01 00:00:00

abstract：:Every year thousands of young teenagers are afflicted with different types of cancer and receive gonadotoxic chemotherapy and radiotherapy regimens, causing depletion of germ cells in the gonads and premature gonadal failure. In this review, we discuss and outline the current strategies and the future directions of fe...

journal_title：Annals of the New York Academy of Sciences

authors： Oktem O,Oktay K

更新日期：2008-01-01 00:00:00

abstract：:A total of 1,098 serum samples were analyzed against Anaplasma phagocytophilum by immunofluorescent antibody (IFA) test. These serum samples belonged to four different populations distributed throughout two provinces of Galicia (Ourense and Pontevedra) located in northwestern Spain: bovine population (456 samples); ov...

journal_title：Annals of the New York Academy of Sciences

authors： Amusategui I,Sainz A,Tesouro MA

更新日期：2006-10-01 00:00:00

abstract：:Saliva testing for drugs of abuse can provide both qualitative and quantitative information on the drug status of an individual undergoing testing. Self-administration by the oral, intranasal, and smoking routes often produces "shallow depots" of drug that contaminate the oral cavity. This depot produces elevated drug...

journal_title：Annals of the New York Academy of Sciences

authors： Cone EJ

更新日期：1993-09-20 00:00:00

abstract：:We have presented evidence indicating that P2-purinergic receptors may activate the polyphosphoinositide-phospholipase C in HL60 cells via the mediation of a pertussis-toxin-sensitive GTP-binding protein, which also mediates the actions of chemotactic peptide receptors in these and other phagocytic white blood cells. ...

journal_title：Annals of the New York Academy of Sciences

authors： Dubyak GR,Cowen DS,Lazarus HM

更新日期：1988-01-01 00:00:00

abstract：:At the alpha(2A)-autoreceptors on the sympathetic nerve terminals of the human atrial appendages and rabbit pulmonary artery, rilmenidine and oxymetazoline exhibit different properties (antagonism and agonism, respectively). These opposite pharmacodynamic properties of alpha(2)-adrenoceptor ligands seem to be due to s...

journal_title：Annals of the New York Academy of Sciences

authors： Molderings GJ,Bonisch H,Bruss M,Gothert M

更新日期：2003-12-01 00:00:00

abstract：:The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK polymorphism, a relative GC resistance has been demonstrated. In vivo, this was suggested by a smaller response to a dexamethasone supp...

journal_title：Annals of the New York Academy of Sciences

authors： Manenschijn L,van den Akker EL,Lamberts SW,van Rossum EF

更新日期：2009-10-01 00:00:00

abstract：:The lobster stomatogastric ganglion contains 30 neurons and when modulated can produce two distinct rhythmic motor patterns--the gastric mill and the pyloric. The complete neural circuitry underlying both patterns is well known. Without modulatory input no patterns are produced, and the neurons fire tonically or are s...

journal_title：Annals of the New York Academy of Sciences

authors： Selverston A,Elson R,Rabinovich M,Huerta R,Abarbanel H

更新日期：1998-11-16 00:00:00

abstract：:Conservation translocation of species varies from restoring historic populations to managing the relocation of imperiled species to new locations. We review the literature in three areas--translocation, managed relocation, and conservation decision making--to inform conservation translocation under changing climates. ...

journal_title：Annals of the New York Academy of Sciences

authors： Schwartz MW,Martin TG

更新日期：2013-05-01 00:00:00

abstract：:West Nile virus (WNV) caused disease outbreaks in Israel in the 1950s and the late 1970s. In 1998 an outbreak of WNV in goose farms and evidence of infection in dead migratory birds were reported. Consequently, human diagnostic services for WNV were resumed, including virus isolation, serology, and RT-PCR. Risk factor...

journal_title：Annals of the New York Academy of Sciences

authors： Bin H,Grossman Z,Pokamunski S,Malkinson M,Weiss L,Duvdevani P,Banet C,Weisman Y,Annis E,Gandaku D,Yahalom V,Hindyieh M,Shulman L,Mendelson E

更新日期：2001-12-01 00:00:00

abstract：:Hamster sperm DNA is packaged so tightly that it is the most highly condensed eukaryotic DNA known. Nevertheless, the sperm genome is also organized in a very specific fashion by two nuclear structures, the nuclear matrix and the nuclear annulus. The nuclear matrix organizes sperm DNA into loop domains approximately 4...

journal_title：Annals of the New York Academy of Sciences

authors： Farrington JE,Patel R,Ward WS

更新日期：1991-01-01 00:00:00

abstract：:There is a significant increase in the percentage and absolute number of activated lymphocytes (OKT10+, IL2R1+) after ECT treatment of major depressive disorder. There is an acute decrease in the absolute number of total lymphocytes, T8+ and Leu11+ cells one hour after a single ECT. ...

journal_title：Annals of the New York Academy of Sciences

authors： Fischler B,Bocken R,Schneider I,De Waele M,Thielemans K,Derde MP

更新日期：1992-04-15 00:00:00

abstract：:The human organism is in a state of dynamic equilibrium, homeostasis. The stress system is activated when homeostasis is challenged by extrinsic or intrinsic forces, the stressors. This system, whose central component is the central nervous system (CNS) and includes corticotropin-releasing hormone (CRH) and noradrener...

journal_title：Annals of the New York Academy of Sciences

authors： Stratakis CA,Chrousos GP

更新日期：1995-12-29 00:00:00

abstract：:In this study, we measured the lymphocyte levels of proteins involved in apoptosis regulation, such as Bcl-2, the peripheral benzodiazepine receptor (PBR), caspase-3, and Cu/Zn superoxide dismutase (Cu/Zn SOD), in patients with Parkinson's disease (PD), either untreated or under therapy with dopaminergic agents (l-Dop...

journal_title：Annals of the New York Academy of Sciences

authors： Blandini F,Mangiagalli A,Cosentino M,Marino F,Samuele A,Rasini E,Fancellu R,Martignoni E,Riboldazzi G,Calandrella D,Frigo GM,Nappi G

更新日期：2003-12-01 00:00:00

abstract：:Isolation of Coxiella Burnetii in the standard laboratory setting is hazardous; therefore most diagnoses are based on retrospective detection of a rising antibody titer to C. burnetti. As a result, this disease is usually undiagnosed or misdiagnosed. Methods for the rapid detection of C. burnetti have now been develop...

journal_title：Annals of the New York Academy of Sciences

authors： Frazier ME,Mallavia LP,Samuel JE,Baca OG

更新日期：1990-01-01 00:00:00

abstract：:We investigated Ca2+ clearance mechanisms (CCMs) at the axon terminals of mammalian central neurons: neurohypophysial (NHP) axon terminals and calyces of Held. Ca2+ transients were evoked by applying a short depolarization pulse via a patch pipette containing Ca2+ indicator dye. Quantitative analysis of the Ca2+ decay...

journal_title：Annals of the New York Academy of Sciences

authors： Lee SH,Kim MH,Lee JY,Lee SH,Lee D,Park KH,Ho WK

更新日期：2007-03-01 00:00:00

abstract：:While the ventral pallidum (VP) is known to be important in relaying information between the nucleus accumbens and target structures, it has become clear that substantial information processing occurs within the VP. We evaluated the possibility that opioid modulation of other transmitters contained in VP afferents is ...

journal_title：Annals of the New York Academy of Sciences

authors： Napier TC,Mitrovic I

更新日期：1999-06-29 00:00:00

abstract：:The Guillain Barré syndromes (GBS) are the world's leading cause of acute autoimmune neuromuscular paralysis. Understanding the pathophysiological events of GBS, and improving immunotherapies are fundamental to improving the clinical outcome. Recent research into GBS and the Miller Fisher syndrome (MFS) variant has fo...

journal_title：Annals of the New York Academy of Sciences

authors： Willison HJ,Plomp JJ

更新日期：2008-01-01 00:00:00

abstract：:Data Sets used in reverse engineering of biochemical networks contain usually relatively few high-dimensional data points, which makes the problem in general vastly underdetermined. It is therefore important to estimate the probability that a given algorithm will return a model of acceptable quality when run on a data...

journal_title：Annals of the New York Academy of Sciences

authors： Just W

更新日期：2007-12-01 00:00:00

abstract：:In amphibians, alpha-MSH secreted by the pars intermedia of the pituitary plays a pivotal role in the process of skin color adaptation. Reciprocally, the skin of amphibians contains a number of regulatory peptides, some of which have been found to regulate the activity of pituitary melanotrope cells. In particular, th...

journal_title：Annals of the New York Academy of Sciences

authors： Vaudry H,Chartrel N,Desrues L,Galas L,Kikuyama S,Mor A,Nicolas P,Tonon MC

更新日期：1999-10-20 00:00:00

abstract：:A major challenge in systems biology is to evaluate the feasibility of a biological research project prior to its realization. Since experiments are animals-, cost- and time-consuming, approaches allowing researchers to discriminate alternative hypotheses with a minimal set of experiments are highly desirable. Given a...

journal_title：Annals of the New York Academy of Sciences

authors： Maiwald T,Kreutz C,Pfeifer AC,Bohl S,Klingmüller U,Timmer J

更新日期：2007-12-01 00:00:00

abstract：:The objectives of ExoMars are to inject an orbiter around Mars and to land a rover on the surface to look for possible traces of life. During the first stages of the feasibility analysis, the mass margin of the orbiter was very small for a direct transfer in the Soyuz/Fregat scenario. An analysis of the combined use o...

journal_title：Annals of the New York Academy of Sciences

authors： Gil-Fernández J,Van Damme CC,Graziano M,Amata GB,Cogo F,Perino MA

更新日期：2005-12-01 00:00:00