Malaria virulence genes controlling expression through chromatin modification.

Abstract:

:Mutually exclusive expression within the var gene family of the malaria parasite Plasmodium falciparum is important for parasite survival and virulence. In this issue of Cell, Duraisingh et al. and Freitas-Junior et al. provide evidence for the role of Sir2-dependent alterations in chromatin structure and changes in subnuclear chromatin localization in regulating var gene expression (Duraisingh et al., 2005; Freitas-Junior et al., 2005).

journal_name

Cell

journal_title

Cell

authors

Deitsch KW

doi

10.1016/j.cell.2005.03.019

subject

Has Abstract

pub_date

2005-04-08 00:00:00

pages

1-2

issue

1

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(05)00291-6

journal_volume

121

pub_type

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