Abstract：
:We have analyzed two mutations of the white-eye gene, which arose in flies subject to I-R hybrid dysgenesis. These mutations are associated with insertions of apparently identical 5.4 kb sequences, which we have cloned. We believe that these insertions are copies of the I factor controlling I-R hybrid dysgenesis. The I factor is not a member of the copia-like or fold-back classes of transposable elements and has no sequence homology with the P factor that controls P-M dysgenesis. All strains of D. melanogaster contain I-factor sequences. Those present in reactive strains must represent inactive I elements. I elements have a remarkably similar sequence organization in all reactive strains and are located in peri-centromeric regions. Inducer strains appear to contain both I elements, located in peri-centromeric regions, and 10-15 copies of the complete I factor at sites on the chromosome arms.
journal_name
Celljournal_title
Cellauthors
Bucheton A,Paro R,Sang HM,Pelisson A,Finnegan DJdoi
10.1016/0092-8674(84)90536-1subject
Has Abstractpub_date
1984-08-01 00:00:00pages
153-63issue
1eissn
0092-8674issn
1097-4172pii
0092-8674(84)90536-1journal_volume
38pub_type
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