The ABA-1 allergen of the nematode Ascaris suum: epitope stability, mass spectrometry, and N-terminal sequence comparison with its homologue in Toxocara canis.

abstract：:The supernatants of hybrids produced by fusion of splenocytes from normal, germ free, nude and neonatal BALB/c mice with mouse NS-1 myeloma cells were examined for immunofluorescence reactivity with viable and acetone fixed monolayers of syngeneic mouse fibroblasts and mouse 3T3 cells and with viable cell suspensions ...

journal_title：Clinical and experimental immunology

authors： Underwood JR,Pedersen JS,Chalmers PJ,Toh BH

更新日期：1985-05-01 00:00:00

abstract：:The effect of a standard laparatomy on antibody synthesis was studied in Wistar R/A rats recieving an intravenous injection of 10(9) sheep red blood cells (SRBC) during the surgical procedure. Anti-SRBC antibody titres were significantly higher in operated animals than in controls. When SRBC were given 2 hr after the ...

journal_title：Clinical and experimental immunology

authors： Kinnaert P,Mahieu A,Van Geertruyden N

更新日期：1978-05-01 00:00:00

abstract：:Antibody reactivity against the 'mitochondrial M2 antigen' was determined in sera from 10 patients with primary biliary cirrhosis (PBC), using Western blotting after SDS-PAGE separation of rat liver mitochondria (RLM) and plasma membrane proteins. The molecular weights of the major M2 antigens in rat liver mitochondri...

journal_title：Clinical and experimental immunology

authors： Sundin U,Sundqvist KG

更新日期：1991-03-01 00:00:00

abstract：:Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with multiple myeloma and systemic lupus erythematosus (SLE). These antibodies desialylate biomolecules, such as glycoproteins, gangliosides and red blood cells. Desialylati...

journal_title：Clinical and experimental immunology

authors： Tomin A,Dumych T,Tolstyak Y,Kril I,Mahorivska I,Bila E,Stoika R,Herrmann M,Kit Y,Bilyy R

更新日期：2015-01-01 00:00:00

abstract：:We assessed whether complement and its factor C4 or abnormal immunoglobulin levels are associated with chronic or recurrent rhinosinusitis. We used multiple patient and control groups to obtain clinically meaningful data. Adult chronic or recurrent rhinosinusitis and acute purulent rhinosinusitis patients were compare...

journal_title：Clinical and experimental immunology

authors： Seppänen M,Suvilehto J,Lokki ML,Notkola IL,Järvinen A,Jarva H,Seppälä I,Tahkokallio O,Malmberg H,Meri S,Valtonen V

更新日期：2006-08-01 00:00:00

abstract：:Neoplastic cells from 49 patients with B cell chronic lymphocytic leukaemia (B-CLL) were studied and compared with normal peripheral and tonsillar B cells using CD21 monoclonal antibodies. Membrane expression of CR2 was quantified by calibrated flow cytometry and by binding analysis with radiolabelled antibody. Both a...

journal_title：Clinical and experimental immunology

authors： Tooze JA,Bevan DH

更新日期：1991-03-01 00:00:00

abstract：:The aim of this study was to evaluate prospectively cytokine levels and disease activity in juvenile idiopathic arthritis (JIA) patients treated with and without tumour necrosis factor (TNF)-α inhibitors. TNF-α inhibitor-naive JIA subjects were followed prospectively for 6 months. Cytokine levels of TNF-α, interleukin...

journal_title：Clinical and experimental immunology

authors： Walters HM,Pan N,Lehman TJ,Adams A,Kalliolias GD,Zhu YS,Santiago F,Nguyen J,Sitaras L,Cunningham-Rundles S,Walsh TJ,Toussi SS

更新日期：2016-06-01 00:00:00

abstract：:Sarcoidosis is a multisystem disease of unknown etiology characterized by non-caseating granulomata, formed mainly from macrophages surrounded by lymphocytes and plasma cells. Using a novel method for the preparation of blood leucocytes for flow cytometry, we report increased expression of LeuCAMs (CD11/CD18) on perip...

journal_title：Clinical and experimental immunology

authors： Shakoor Z,Hamblin AS

更新日期：1992-10-01 00:00:00

abstract：:A microplate radioimmunoassay for IgG, IgA and IgM antiglobulins reactive with rabbit IgG was performed on sera from 69 patients with various connective tissue diseases. IgM antiglobulins were detected in rheumatoid arthritis, systemic sicca syndrome and some patients with systemic vasculitis. IgA antiglobulins were f...

journal_title：Clinical and experimental immunology

authors： Elkon KB,Caeiro F,Gharavi AE,Patel BM,Ferjencik PP,Hughes GR

更新日期：1981-12-01 00:00:00

abstract：:We have examined the cell-mediated immunity (CMI) to Staphylococcus aureus (S. aureus) and Staphylococcal enterotoxin B (SEB) in peripheral blood mononuclear cells (PBMC) from children with atopic dermatitis (AD) and from non-atopic child controls by measurement of proliferative responses and production of the cytokin...

journal_title：Clinical and experimental immunology

authors： Campbell DE,Kemp AS

更新日期：1997-02-01 00:00:00

abstract：:This study examined the expression of the inhibitory receptor, leucocyte-associated immunoglobulin (Ig)-like receptor-1 (LAIR-1) in fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA) patients to investigate its potential role in the modulation of inflammatory cytokines, matrix metalloproteinases (MMPs) an...

journal_title：Clinical and experimental immunology

authors： Zhang Y,Wang S,Dong H,Yi X,Zhang J,Liu X,Zhuang R,Ding Y

更新日期：2018-05-01 00:00:00

abstract：:CD4+CD25+ T regulatory cells may play a role in the different clinical presentations of chronic hepatitis C virus (HCV) infection by suppressing CD4+ T cell responses. Peripheral CD4+CD25+ T cells from chronic HCV carriers with normal and abnormal alanine aminotransferase (ALT) were analysed for specificity and effect...

journal_title：Clinical and experimental immunology

authors： Bolacchi F,Sinistro A,Ciaprini C,Demin F,Capozzi M,Carducci FC,Drapeau CM,Rocchi G,Bergamini A

更新日期：2006-05-01 00:00:00

abstract：:Protection against intracellular pathogens such as Mycobacterium leprae is critically dependent on the function of NK cells at early stages of the immune response and on Th1 cells at later stages. In the present report we evaluated the role of IL-18 and IL-13, two cytokines that can influence NK cell activity, in the ...

journal_title：Clinical and experimental immunology

authors： de la Barrera S,Finiasz M,Fink S,Ilarregui J,Aleman M,Olivares L,Franco MC,Pizzariello G,del Carmen Sasiain M

更新日期：2004-01-01 00:00:00

abstract：:In this study we demonstrate that IgG present in the sera of patients with primary Sjögren's syndrome (PSS) could bind and activate muscarinic acetylcholine receptors (mAChRs) of rat parotid gland. These antibodies were able to inhibit in a non-competitive manner the binding of 3H-quinuclidinyl benzilate (QNB) to mACh...

journal_title：Clinical and experimental immunology

authors： Bacman S,Sterin-Borda L,Camusso JJ,Arana R,Hubscher O,Borda E

更新日期：1996-06-01 00:00:00

abstract：:Activation of human umbilical vein endothelial (HUVE) cells with the inflammatory mediators tumour necrosis factor-alpha (TNF), interleukin-1 (IL-1), lipopolysaccharide (LPS) and phorbol esters enhanced their adhesiveness for leucocytes. The appearance of an activation antigen ELAM-1, recognized by a monoclonal antibo...

journal_title：Clinical and experimental immunology

authors： Leeuwenberg JF,Jeunhomme GM,Buurman WA

更新日期：1990-09-01 00:00:00

abstract：:Both the complement system and tissue factor (TF), a key initiating component of coagulation, are activated in sepsis, and cross-talk occurs between the complement and coagulation systems. C1-inhibitor (C1-INH) can act as a regulator in both systems. Our aim in this study was to examine this cross-talk by investigatin...

journal_title：Clinical and experimental immunology

authors： Landsem A,Nielsen EW,Fure H,Christiansen D,Ludviksen JK,Lambris JD,Østerud B,Mollnes TE,Brekke OL

更新日期：2013-08-01 00:00:00

abstract：:Ro ribonucleoproteins (RNPs) are autoantigens that result from the association of a 60-kDa protein (Ro60) with a small RNA (hY1, hY3, hY4 or hY5 in humans, mY1 or mY3 in mice). Previous studies localized Ro RNPs to the cytoplasm. Because Ro RNPs containing hY5 RNA (Ro(hY5) RNPs) have unique biochemical and immunologic...

journal_title：Clinical and experimental immunology

authors： Gendron M,Roberge D,Boire G

更新日期：2001-07-01 00:00:00

abstract：:One hundred and sixty-two unrelated, healthy normals and 118 unrelated SLE patients were subdivided by sex, race, and disease, and each group was in Hardy-Weinberg equilibrium for autosomal codominant expression of the four CR1 alleles. There were no significant phenotypic differences between males and females (P grea...

journal_title：Clinical and experimental immunology

authors： Van Dyne S,Holers VM,Lublin DM,Atkinson JP

更新日期：1987-06-01 00:00:00

abstract：:Supernatants of concanavalin A (Con A)-activated human spleen cells have been previously shown to inhibit polyclonal immunoglobulin (Ig) biosynthesis by pokeweed mitogen (PWM)-stimulated human spleen and peripheral blood mononuclear cells. In the present study, hydrocortisone was added at the beginning of in vitro cul...

journal_title：Clinical and experimental immunology

authors： Ilfeld D,Krakauer RS

更新日期：1982-04-01 00:00:00

abstract：:It has been shown that bronchoalveolar lavages (BALs) from patients with sarcoidosis and other interstitial lung diseases contain abnormally increased numbers of alveolar macrophages (AM) expressing antigens found on monocytes. The aim of this study was to compare the phenotype of AM from patients with sarcoidosis wit...

journal_title：Clinical and experimental immunology

authors： Barbosa IL,Gant VA,Hamblin AS

更新日期：1991-10-01 00:00:00

abstract：:Serum samples from 64 apparently healthy individuals (32 men and 32 women, mean age 81.0 years) were examined for the prevalence of several autoantibodies, including rheumatoid factor (RF), antinuclear antibodies (ANA), antibodies to extracted cellular antigens Ro (SSA), La (SSB), Sm, U1nRNP and Scl-70. IgG and IgM is...

journal_title：Clinical and experimental immunology

authors： Manoussakis MN,Tzioufas AG,Silis MP,Pange PJ,Goudevenos J,Moutsopoulos HM

更新日期：1987-09-01 00:00:00

abstract：:Antibody response and antigen specific suppression to bovine serum albumin (BSA) in uremic rats have been investigated. Primary immune response was found to be significantly reduced independent of the route of administration or adjuvant while secondary response was affected only in animals in which a weak adjuvant suc...

journal_title：Clinical and experimental immunology

authors： Mezzano S,Pesce A,Peters T Jr,Pollak VE,Reed R,Michael G

更新日期：1982-04-01 00:00:00

abstract：:Primary biliary cholangitis (PBC) is a multi-factorial disease caused by the interaction of both genetic predisposition and environmental triggers. Bacterial infection has been investigated most intensively, both epidemiologically and experimentally, as a prime environmental aetiology in PBC. The association of recurr...

journal_title：Clinical and experimental immunology

authors： Tanaka A,Leung PSC,Gershwin ME

更新日期：2019-01-01 00:00:00

abstract：:Dipeptidyl peptidase IV (DPIV), a T cell enzyme, has been implicated in the regulation of lymphocyte proliferation in response to lectins and allogeneic cells. A sensitive fluorimetric assay has been established for the enzyme and used to investigate DPIV activity, kinetics and the subcellular localization in lymphocy...

journal_title：Clinical and experimental immunology

authors： Harland C,Shah T,Webster AD,Peters TJ

更新日期：1988-11-01 00:00:00

abstract：:Two-stage stimulation of SK activity of normal human peripheral blood lymphocytes by soluble factors was demonstrated. The first stage was initiated by factors present in supernatant derived from normal B-LCL cultures. Only cell lines which could induce SK activity in culture in an MLR-type reaction had the capacity t...

journal_title：Clinical and experimental immunology

authors： Hofman FM,Spina CA

更新日期：1980-12-01 00:00:00

abstract：:Autoantigens in canine autoimmune haemolytic anaemia (AIHA) were identified by immunoprecipitation using autoantibody eluted from the erythrocytes of affected dogs. At least three patterns of precipitated antigen were identified in six cases of AIHA. The most commonly precipitated antigen pattern was a combination of ...

journal_title：Clinical and experimental immunology

authors： Barker RN,Gruffydd-Jones TJ,Stokes CR,Elson CJ

更新日期：1991-07-01 00:00:00

abstract：:It has been demonstrated immunohistologically using cryostat sections that the lectins PHA and Con A bind to human placentae. Both lectins stain trophoblastic basement membrane (TBM), perivascular tissue and stroma. No staining of trophoblasts was observed. It has been shown by blocking experiments that the lectin bin...

journal_title：Clinical and experimental immunology

authors： Johnson PM,Faulk WP

更新日期：1976-06-01 00:00:00

abstract：:Interleukin (IL)-22 is a cytokine involved in inflammatory and wound healing processes that is secreted primarily by T helper type 17 (Th17) cells. IL-22 receptor (IL-22R) expression is limited to epithelial cells of the digestive organs, respiratory tract and skin. Most tumours originating in these sites over-express...

journal_title：Clinical and experimental immunology

authors： Curd LM,Favors SE,Gregg RK

更新日期：2012-05-01 00:00:00

abstract：:This study aimed to examine whether acute intermittent porphyria (AIP) is associated with systemic inflammation and whether the inflammation correlates with disease activity. A case-control study with 50 AIP cases and age-, sex- and place of residence-matched controls was performed. Plasma cytokines, insulin and C-pep...

journal_title：Clinical and experimental immunology

authors： Storjord E,Dahl JA,Landsem A,Fure H,Ludviksen JK,Goldbeck-Wood S,Karlsen BO,Berg KS,Mollnes TE,W Nielsen E,Brekke OL

更新日期：2017-03-01 00:00:00

abstract：:The expression of cytokine mRNA species was determined in liver biopsies from six normal subjects, 18 patients with PBC and 14 patients with hepatitis B e antigen (HBeAg)-positive CHB using a reverse transcriptase-polymerase chain reaction (RT-PCR) technique. cDNA, obtained by reverse transcription using oligo d(T) pr...

journal_title：Clinical and experimental immunology

authors： Shindo M,Mullin GE,Braun-Elwert L,Bergasa NV,Jones EA,James SP

更新日期：1996-08-01 00:00:00