Abstract:
:Ninety-one patients treated with amitriptyline and 60 normal control subjects underwent a standardized heart rate analysis in supine posture. Tests included the determination of time- and frequency-derived measurements of heart rate variability. The patients differed significantly from the control subjects in all parameters investigated. Two-thirds of the patients treated with a tricyclic antidepressant (TCA) reached values that met the criteria for cardiovascular autonomic neuropathy. Our results provide evidence that heart rate analysis might be a more sensitive tool in diagnosing amitriptyline-associated anticholinergic delirium than determination of TCA plasma levels. Further research is needed to elucidate what implications the TCA-associated alteration of autonomic cardiovascular function might have for patients.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Rechlin T,Weis M,Claus D,Kaschka WPdoi
10.1016/0165-1781(95)02511-tsubject
Has Abstractpub_date
1995-04-28 00:00:00pages
279-87issue
3eissn
0165-1781issn
1872-7123pii
0165-1781(95)02511-Tjournal_volume
56pub_type
杂志文章abstract::To evaluate the influence of weight loss on the dexamethasone suppression test (DST), we studied 61 patients with major depressive disorder as defined by the Research Diagnostic Criteria, 59 healthy normal volunteers, and 16 volunteers who lost weight by dieting. Nonsuppression on the DST was not correlated to weight ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90015-5
更新日期:1984-06-01 00:00:00
abstract::Bipolar disorder (BD) adversely affects daily activities/functioning. The Sheehan Disability Scale (SDS) assesses disability in work/school activities, family relationships, and social functioning, and it evaluates the functional impact of psychiatric disorders. BD outpatients from 21 U.S. sites completed a battery of...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.11.018
更新日期:2009-01-30 00:00:00
abstract::To adapt the Center for Epidemiologic Studies Depression Scale for use in non-psychiatric Spanish populations, a Spanish translation of the scale was interviewer-administered to 554 subjects aged 18-34 years (65.9% women) and the ratings so obtained were compared with the SCID-CV-based diagnoses of expert clinicians. ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.03.004
更新日期:2007-01-15 00:00:00
abstract::Cerebral activation during memory encoding and retrieval might depend on subjects' learning capacity, either by corresponding to better performance in superior learners or by reflecting increased effort in inferior learners. To investigate these alternative hypotheses, the study compared cerebral activation during enc...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2004.01.007
更新日期:2004-11-15 00:00:00
abstract::Patients with a first episode of schizophrenia generally have increased phospholipid membrane breakdown products within the brain, while findings in chronic patients have been inconsistent. In this study we examine progressive changes in phosphorus membrane metabolites in the same patient group through the early years...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.06.017
更新日期:2012-01-30 00:00:00
abstract::The Delirium Motor Subtype Scale (DMSS) was developed by discerning the best differentiating motor activity symptoms from the Delirium Motor Checklist (DMC), a compilation of psychomotor symptoms from other subjective scales. To broaden its validation we replicated the original work done in a palliative care populatio...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.08.034
更新日期:2013-03-30 00:00:00
abstract::Veterans with schizophrenia admitted for suicidal ideation were recruited into a post-discharge program consisting of Intensive Case Monitoring (ICM) with daily monitoring with the Health Buddy (HB; experimental group) or ICM alone (control group). This study tested the feasibility of the telehealth monitoring interve...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2016.02.049
更新日期:2016-05-30 00:00:00
abstract::Stigmatisation towards depression has previously been reported amongst medical students from a variety of backgrounds. This study explored personal and perceived stigmas associated with depression, and their relationship with demographics, knowledge of depression, levels of personal stress and history of medical illne...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.03.003
更新日期:2013-10-30 00:00:00
abstract::The purpose of the current study was to evaluate the relationship between emotional exhaustion and suicide risk in emergency responders. Participants included 643 actively employed emergency responders who responded to an online research based survey. Participants were administered the Maslach Burnout Inventory (MBI; ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113379
更新日期:2020-11-01 00:00:00
abstract::The current studies examined the role of 'not just right' experiences (NJREs) and incompleteness (INC) in body dysmorphic disorder (BDD). In Study 1, a clinical BDD sample endorsed more severe NJREs than healthy controls, when controlling co-occurring symptoms of depression and anxiety. In Study 2, INC predicted react...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.11.038
更新日期:2017-01-01 00:00:00
abstract::The DSM-IV describes pathological gambling as a chronic condition with an insidious course. However, several extant studies characterize pathological and problem gambling as fluctuating over time. The present analyses expand on previous reports by evaluating changes in pathological gambling symptoms across the lifetim...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.05.015
更新日期:2007-07-30 00:00:00
abstract::Discrepancies between scores on the Hamilton Depression Rating Scale (HAMD) and the Beck Depression Inventory (BDI), as well as differences regarding their sensitivity to detect change, have been reported. This study investigates discrepancies and their potential prediction on the basis of demographic, personality, an...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.11.014
更新日期:2012-06-30 00:00:00
abstract::Depressive symptoms are common in children and adolescents. The prevalence of depressive symptoms in children and adolescents in China vary significantly across studies. A meta-analysis of the prevalence of depressive symptoms in children and adolescents in China was conducted. Literature search was performed in both ...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2018.12.133
更新日期:2019-02-01 00:00:00
abstract::The main aim of this study was to investigate serum levels of adiponectin in adult patients with attention deficit hyperactivity disorder (ADHD). The second objective was to examine the effects of rare missense mutations in T-cadherin, an adiponectin receptor encoded by the ADHD candidate gene CDH13, on serum adiponec...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.01.025
更新日期:2014-04-30 00:00:00
abstract::The processing of social stimuli generated by one's own voluntary behavior is an element of social adaptation. It is known that self-generated stimuli induce attenuated sensory experiences compared with externally generated stimuli. The present study aimed to examine this self-specific attenuation effect on early stim...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.12.037
更新日期:2019-01-01 00:00:00
abstract::In the current study, we investigated how individual variants in the serotonin promoter gene, previously associated with smoking cessation and linked to anxiety-related personality traits, were associated with individual differences in responsiveness to bupropion and cognitive behavioral therapy (CBT) in a clinical po...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.psychres.2008.12.015
更新日期:2010-01-30 00:00:00
abstract::The prevalence of symptoms of anorexia nervosa among students majoring in the areas of dance, drama, physical education, and English was determined by using the Eating Attitudes Test (EAT). It was hypothesized that female students who might be prone to develop anorexia nervosa as indicated by anorectic symptoms on the...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(82)90052-x
更新日期:1982-08-01 00:00:00
abstract::This study examined whether cognitive measures of response inhibition derived from the AX-CPT are able to differentiate between adult attention deficit/hyperactivity disorder (ADHD), borderline personality disorder (BPD), and healthy controls (HC). Current DSM-IV-TR symptoms of ADHD and BPD were assessed by structured...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.12.034
更新日期:2014-03-30 00:00:00
abstract::The relationship between severity of tardive dyskinesia (TD) and the prominence of negative symptoms was assessed in 25 right-handed, medicated schizophrenic patients. TD was quantified using ultrasound detectors and frequency measurement techniques as well as with observer rating scales. Electromechanical studies rev...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(89)90042-5
更新日期:1989-05-01 00:00:00
abstract::Wisconsin Card Sorting Test (WCST) performances were studied in 33 patients with obsessive-compulsive disorder (OCD) and 33 age-, sex-, and education-matched normal comparison subjects; the OCD patients were divided into four subgroups on the basis of their symptomatology. Neither the two groups of subjects nor the fo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02670-r
更新日期:1995-09-08 00:00:00
abstract::The aim of this study was to assess the association between anhedonia and metabolic syndrome (MetS) in a well-characterized community sample of individuals with a current depressive episode. This is a cross-sectional study with young adults aged 24-30 years old. Depressive episode and the presence of anhedonia was ass...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.009
更新日期:2019-01-01 00:00:00
abstract::Although emotional deficits in schizotypy have been reported, the exact nature of these deficits is not well understood. The goal of the current research was to further differentiate possible emotion deficits in schizotypy. In the current study, individuals with elevated social anhedonia (SocAnh; n=54) and elevated pe...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.12.028
更新日期:2011-05-15 00:00:00
abstract::This study was designed to determine the effects of aging on the volume of the basal ganglia in individuals with Down syndrome (DS) and to examine the relationship between basal ganglia volumes, neuropsychological test performance, and dementia status in this population. Subjects were 32 adults with DS. Basal ganglia ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(97)00011-5
更新日期:1997-05-16 00:00:00
abstract::The cognitive significance of P300 abnormalities in schizophrenia and obsessive-compulsive disorder (OCD) was investigated. P300 was measured by an auditory oddball paradigm, in which a series of standard tones (1000 Hz) and target tones (1500 Hz) were presented. The subject's task was to count the number of the prese...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(03)00045-3
更新日期:2003-06-30 00:00:00
abstract::The aim of this study was to gain a better understanding of schizophrenia patients' strategic use of learning time allocation during encoding, and determine whether they are able to use their monitoring and previous performances to adapt their learning behavior efficiently. Schizophrenia is considered to be a patholog...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.07.036
更新日期:2012-01-30 00:00:00
abstract::Alterations in secretion of stress hormones within the hypothalamic-pituitary-adrenal (HPA) axis have repeatedly been found in substance-related addictive disorders. It has been suggested that glucocorticoids might contribute to the development and maintenance of substance use disorders by facilitatory effects on beha...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.11.078
更新日期:2015-03-30 00:00:00
abstract::The 2-deoxyglucose (2-DG) method was used to study regional metabolic changes in rats following chronic d-amphetamine treatment without subsequent challenges. Four groups of rats were pretreated (intraperitoneal administration) with d-amphetamine (0, 1, 5, or 10 mg/kg) once per day for 14 days. After a 7-day abstinenc...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(95)02496-j
更新日期:1995-06-29 00:00:00
abstract::A number of studies measured lead levels in hair from children with autism spectrum disorder (ASD) to detect the relationship between cumulated lead exposure and the development of ASD, but results are inconsistent. We aimed to conduct a systematic review and meta-analysis using the published studies to explore the ac...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2019.05.022
更新日期:2019-06-01 00:00:00
abstract::We wished to determine whether decreases in prefrontal glutamate concentrations occur in offspring of parents with bipolar disorder with and at high risk for mania. Sixty children and adolescents, 9-18 years old, of parents with bipolar I or II disorder (20 offspring with established history of mania, "BD", 20 offspri...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2010.01.003
更新日期:2010-05-30 00:00:00
abstract::In a review of the current literature, we identified (1)H MRS studies of major depressive disorder (MDD) that examined the metabolites N-acetylaspartate (NAA), choline (Cho), myo-inositol (mI), glutamate/glutamine/gamma-aminobutyric acid-GABA (Glx), and creatine (Cr). Separate meta-analyses comparing adult and pediatr...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.pscychresns.2005.12.004
更新日期:2006-06-30 00:00:00