Abstract:
:Cerebral activation during memory encoding and retrieval might depend on subjects' learning capacity, either by corresponding to better performance in superior learners or by reflecting increased effort in inferior learners. To investigate these alternative hypotheses, the study compared cerebral activation during encoding and retrieval of a motor sequence in groups of subjects with superior and inferior learning performances. Ten healthy subjects underwent functional magnetic resonance imaging (fMRI) while performing a motor sequence encoding paradigm (i.e. finger tapping sequence) and a retrieval paradigm (i.e. reproduction of the learned sequence). Subjects were divided into superior and inferior learners according to the correctness of sequence reproduction during retrieval. During encoding, there was strong bilateral activation in the middle frontal gyrus, the supplementary motor area (SMA), the lateral parietal lobe and the cerebellum. During retrieval, again strong activation was found in identical areas of the prefrontal cortex, the parietal lobe and the cerebellum. During encoding, inferior learners showed more left-sided activations in the left middle frontal and inferior parietal gyri. Superior learners showed increased activation in the corresponding right-sided brain areas during encoding as well as during retrieval. Differences of cerebral activations in the prefrontal and parietal cortex during encoding and retrieval were found to be related to retrieval performance, i.e. success and effort. Further intervention studies are needed to assess whether these interindividual differences are the cause or the consequence of differences in memory performance.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Heun R,Freymann N,Granath DO,Stracke CP,Jessen F,Barkow K,Reul Jdoi
10.1016/j.pscychresns.2004.01.007subject
Has Abstractpub_date
2004-11-15 00:00:00pages
19-32issue
1eissn
0165-1781issn
1872-7123pii
S0925-4927(04)00075-7journal_volume
132pub_type
杂志文章abstract::MIR137, a brain expressed miRNA, has been identified as a top novel susceptibility gene for schizophrenia (SZ). 230 healthy participants completed the Stroop test and were genotyped for a functional Variable Number Tandem Repeat (VNTR) in MIR137 gene. MIR137 VNTR genotypes were associated with differences in Stroop fa...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.01.006
更新日期:2016-02-28 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.09.048
更新日期:2013-03-30 00:00:00
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journal_title:Psychiatry research
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更新日期:2018-07-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2016.11.035
更新日期:2017-05-01 00:00:00
abstract::Bipolar disorder (BD) adversely affects daily activities/functioning. The Sheehan Disability Scale (SDS) assesses disability in work/school activities, family relationships, and social functioning, and it evaluates the functional impact of psychiatric disorders. BD outpatients from 21 U.S. sites completed a battery of...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.11.018
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113250
更新日期:2020-09-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.03.008
更新日期:2015-06-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.037
更新日期:2015-03-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00185-9
更新日期:2003-09-30 00:00:00
abstract::Most investigators have measured binding of 3H-imipramine to platelet membranes, but some of the preparations may have contained varying proportions of intracellular protein because of contamination with incompletely lysed platelets. Since binding to membranes has been expressed with reference to the amount of protein...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90070-4
更新日期:1988-11-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112685
更新日期:2020-02-01 00:00:00
abstract::Proton magnetic resonance spectroscopy ((1)H MRS) has revealed biochemical alterations in various psychiatric disorders. Changes in brain metabolites may be caused not only by the disease's progression or response to treatment, but also by physiological variability. The aim of this study was to use (1)H MRS to assess ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2006.01.010
更新日期:2006-06-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.01.036
更新日期:2014-05-30 00:00:00
abstract::Five women with primary major bipolar affective disorders had variable and at times very high urinary phenylethylamine (PEA) excretion rates. The clinical picture of these patients was characterized by periodic bizarre behaviors and short psychotic episodes. These patients were generally nonresponsive to the usual tre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(82)90009-9
更新日期:1982-04-01 00:00:00
abstract::The Center for Epidemiologic Studies Depression Scale (CES-D) has been used extensively in community-based surveys to describe and explain the prevalence of depression in the general population. Yet, questions have been raised regarding its adequacy for use among ethnic minority because of its factor variance. Employi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2010.06.022
更新日期:2010-08-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.08.008
更新日期:2015-10-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.10.047
更新日期:2018-12-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.041
更新日期:2017-12-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.058
更新日期:2017-04-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.11.020
更新日期:2014-02-28 00:00:00
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journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(92)90093-i
更新日期:1982-10-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.03.040
更新日期:2014-08-15 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2012.08.004
更新日期:2013-03-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(84)90056-8
更新日期:1984-10-01 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.12.012
更新日期:2005-09-15 00:00:00
abstract::While research using Experience Sampling Methodology (ESM) suggests that, in general, contact with relatives or friends may be protective for psychotic experiences, contact with high-Expressed Emotion (high-EE) relatives can have adverse consequences for patients. This study investigated whether contact with high-EE r...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.08.060
更新日期:2016-11-30 00:00:00
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journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.09.029
更新日期:2012-04-30 00:00:00
abstract::Previous studies have shown an association between suicidal behavior and schizophrenia. However, little is known about this association in those with psychotic experiences and symptoms that do not meet the criteria for full psychosis. The aim of the study was to investigate how psychosis risk symptoms are associated w...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.031
更新日期:2015-02-28 00:00:00
abstract::Animal models and clinical trials in humans suggest that probiotics can have an anxiolytic effect. However, no studies have examined the relationship between probiotics and social anxiety. Here we employ a cross-sectional approach to determine whether consumption of fermented foods likely to contain probiotics interac...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.04.023
更新日期:2015-08-15 00:00:00
abstract::Suicidal behavior is a major health risk in psychiatric disorders, especially in schizophrenia, wherein up to 10% patients will commit suicide. However, the neurobiology of suicide is still unclear. Suicidality has been related to decreased central serotonergic (5-hydroxytryptamine, 5-HT) function and reduced choleste...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.08.012
更新日期:2007-02-28 00:00:00