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A functional variant in MIR137, a candidate gene for schizophrenia, affects Stroop test performance in young adults.

Abstract：

:MIR137, a brain expressed miRNA, has been identified as a top novel susceptibility gene for schizophrenia (SZ). 230 healthy participants completed the Stroop test and were genotyped for a functional Variable Number Tandem Repeat (VNTR) in MIR137 gene. MIR137 VNTR genotypes were associated with differences in Stroop facilitation and accuracies in congruent trials and for the total number of errors. This is the first study of the functional VNTR in MIR137 gene and Stroop test performance in healthy subjects. Our results could have important implications for the identification of genetic candidates for endophenotypes for SZ.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

González-Giraldo Y,González-Reyes RE,Forero DA

doi

10.1016/j.psychres.2016.01.006

subject

Has Abstract

pub_date

2016-02-28 00:00:00

pages

202-205

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(15)30349-8

journal_volume

236

pub_type

杂志文章

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