Abstract:
:To evaluate the influence of weight loss on the dexamethasone suppression test (DST), we studied 61 patients with major depressive disorder as defined by the Research Diagnostic Criteria, 59 healthy normal volunteers, and 16 volunteers who lost weight by dieting. Nonsuppression on the DST was not correlated to weight loss in the depressed patients. Of the healthy volunteers, 12.5% converted to nonsuppression status. This conversion rate is not significantly different from nonsuppression rates in the normal population. Implications of these findings are discussed.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Yerevanian BI,Baciewicz GJ,Iker HP,Privitera MRdoi
10.1016/0165-1781(84)90015-5subject
Has Abstractpub_date
1984-06-01 00:00:00pages
155-60issue
2eissn
0165-1781issn
1872-7123pii
0165-1781(84)90015-5journal_volume
12pub_type
杂志文章abstract::Psychomotor changes are reported to be 'nearly always present' in the melancholic subtype of major depressive episode (MDE) in DSM-IV-TR, and are believed by some researchers to be markers of melancholia. The aim of this study was to compare melancholic and atypical forms of MDE and to determine whether psychomotor ch...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00241-x
更新日期:2002-11-15 00:00:00
abstract::The association between orbital frontal cortex (OFC) volume and aggression was investigated in an at-risk psychiatric population. Forty-one psychiatric patients were referred for magnetic resonance imaging and a standardized psychometric assessment of aggression (Lifetime History of Aggression-Revised). Nineteen match...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2008.03.007
更新日期:2009-03-31 00:00:00
abstract::Implementation science is focused on maximizing the adoption, appropriate use, and sustainability of effective clinical practices in real world clinical settings. Many implementation science questions can be feasibly answered by fully experimental designs, typically in the form of randomized controlled trials (RCTs). ...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.06.027
更新日期:2020-01-01 00:00:00
abstract::Stable neuropsychological deficits may provide a reliable basis for identifying etiological subtypes of schizophrenia. The aim of this study was to identify clusters of individuals with schizophrenia based on dimensions of neuropsychological performance, and to characterize their neural correlates. We acquired neurops...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.08.008
更新日期:2015-10-30 00:00:00
abstract::This report describes a computer program for applying a new statistical method for determining levels of agreement, or reliability, when multiple examiners evaluate a single subject. The statistics that are performed include the following: an overall level of agreement, expressed as a percentage, that takes into accou...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(97)00093-0
更新日期:1997-08-29 00:00:00
abstract::Patients with a first episode of schizophrenia generally have increased phospholipid membrane breakdown products within the brain, while findings in chronic patients have been inconsistent. In this study we examine progressive changes in phosphorus membrane metabolites in the same patient group through the early years...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2011.06.017
更新日期:2012-01-30 00:00:00
abstract::The tryptophan catabolite (TRYCAT) pathway is induced by indoleamine 2,3-dioxygenase (IDO), which upon activation depletes plasma tryptophan (TRP) and increases the synthesis of TRYCATs. Both phenomena are associated with somatization and depression. The aims of this study are to examine whether disorders in the TRYCA...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.09.029
更新日期:2012-04-30 00:00:00
abstract::Previous research indicates that interactions between FKBP5 single nucleotide polymorphisms (SNPs) and child abuse are associated with posttraumatic stress disorder (PTSD) in adulthood. We examined the relationship between the T-allele of the rs1360780 FKBP5 SNP and child abuse on PTSD and the HPA axis in a clinical s...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.03.037
更新日期:2018-12-01 00:00:00
abstract::The association of traumatic brain injuries (TBI) with criminality, substance-related disorders and conduct disorders has mainly been studied in adult populations. In our study we examine the association in an adolescent population. We used a population-based clinical sample of 508 psychiatric inpatient adolescents fr...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.04.018
更新日期:2012-12-30 00:00:00
abstract::Cardiovascular and catecholamine responses to mental stressors were investigated in women with bulimia nervosa (BN) and in healthy control subjects. Fifteen women with BN and 15 control subjects completed psychosocial questionnaires before laboratory testing, where they were exposed to an interpersonally based speech ...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-1781(98)00057-2
更新日期:1998-07-27 00:00:00
abstract::Emotion has been conceptualized as a dimensional construct, while the number of dimensions - two or three - has been debated. Research has consistently identified two dimensions - valence and arousal - though ample evidence exists that three dimensions are necessary to describe emotion. One proposed third dimension, i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2013.11.007
更新日期:2014-02-28 00:00:00
abstract::We evaluated the effects of repeated subanesthetic ketamine infusions on suicidal ideation (SI) in patients with major depression. 82 subjects with treatment-resistant unipolar and bipolar depression completed a two-site open-label case-series of repeated (up to four weeks) infusions of ketamine (0.5 mg/kg). Ketamine ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113645
更新日期:2020-12-16 00:00:00
abstract::The phosphoinositide 3 kinase - protein kinase B (PI3K-Akt) signaling pathway plays an important role in the dopamine D2 receptor (DRD2) pathway and in the pathophysiology of schizophrenia. This study measured the mRNA levels of DRD2, PI3KCB, and AKT1 in peripheral blood samples from 24 acute schizophrenia patients an...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.07.010
更新日期:2016-09-30 00:00:00
abstract::Although Adjustment Disorder as a diagnostic category is widely used in clinical practice it is critically discussed that it has not been conceptualized as a category with unique symptoms. Hence, the conceptualization of Adjustment Disorder is subject to substantive change in ICD-11 including core symptoms and additio...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.07.010
更新日期:2015-10-30 00:00:00
abstract::Indirect evidence suggests partially common pathogenetic mechanisms for Neurological Soft Signs (NSS), neurocognition, and social cognition in schizophrenia. However, the possible association between NSS and mentalizing impairments has not yet been examined. In the present study, we assessed the ability to attribute m...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.04.014
更新日期:2014-08-15 00:00:00
abstract::Schema theory and therapy may be an additional therapeutic approach to identify and treat chronic psychological problems, namely early maladaptive schemas (EMSs), in patients with obsessive-compulsive disorder (OCD) and panic disorder (PAD). In the current study, we investigated the characteristics in EMSs between pat...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.11.015
更新日期:2015-12-30 00:00:00
abstract::Neuroendocrine studies that examine the changes in serum prolactin levels following intramuscular (im) neuroleptics have usually monitored prolactin levels before and for 90 minutes to 3 hours after neuroleptic injection. Recent studies have suggested that this may be an inadequate period of time. In the present study...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(79)90056-8
更新日期:1979-10-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) is frequently associated with major depressive disorder, and antidepressants have been reported to ameliorate PTSD symptoms in some patients. The present study assessed the number and affinity of platelet imipramine binding sites, as a marker of the serotonin transporter complex, i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(96)02760-6
更新日期:1996-07-31 00:00:00
abstract::The purpose of the current study was to evaluate the relationship between emotional exhaustion and suicide risk in emergency responders. Participants included 643 actively employed emergency responders who responded to an online research based survey. Participants were administered the Maslach Burnout Inventory (MBI; ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113379
更新日期:2020-11-01 00:00:00
abstract::Several existing laboratory-based stress paradigms have significant shortcomings for assessing neurobiological correlates of stress in healthy volunteers and severely ill psychiatric patients. We have examined neuroendocrine effects of stress associated with the lumbar puncture (LP) procedure in drug-free depressed an...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(88)90050-9
更新日期:1988-08-01 00:00:00
abstract::Suicide is the second cause of death in youth population. The aim of the present study was to analyze demographic characteristics and suicide methods used, as well as to identify gender differences among Mexican children and adolescents (aged 10-17 years) that committed suicide. Between January 2003 and December 2013,...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.09.083
更新日期:2017-12-01 00:00:00
abstract::Evaluating whether certain subtypes of Major Depressive Disorder (MDD) are more strongly associated with Substance Use Disorders (SUDs) may help clarify reasons for MDD-SUD relations. Therefore, this study compared DSM-IV-defined non-atypical/non-melancholic depression (undifferentiated depression; n=365), atypical de...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2007.10.014
更新日期:2008-10-30 00:00:00
abstract::Prior studies found small effects of chronic smoking on spatial and color vision, but they were inconclusive. This study tries to: (1) replicate and extend these previous findings, and (2) rule in that this relationship is pronounced by tobacco addiction. Data were recorded in 71 healthy controls (M = 33.5 years; SD =...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.11.024
更新日期:2019-01-01 00:00:00
abstract::The claim that the prefrontal cortex, particularly its orbito-frontal part, is involved in obsessive-compulsive disorder (OCD) is based upon evidence from neuroimaging as well as behavioral studies. Studies have repeatedly suggested problems with delayed alternation learning in OCD, an executive dysfunction that presu...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.09.003
更新日期:2009-11-30 00:00:00
abstract::Cytochrome P450 C19 (CYP2C19) metabolizes exogenous and endogenous compounds. Although CYP2C19 is highly expressed in the liver, it is also expressed in the brain during early life. Previous human and animal studies have linked CYP2C19 genotype-predicted enzyme activity to hippocampal volumes, depressive symptoms, and...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.112984
更新日期:2020-06-01 00:00:00
abstract::Up to 90% of individuals with schizophrenia suffer from nicotine dependence. Both schizophrenia and nicotine consumption have strong genetic components, which may overlap. The relationship between schizophrenia and nicotine dependence remains unclear, due in part to confounding factors. Studies of the relationship bet...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.07.054
更新日期:2012-12-30 00:00:00
abstract::Although a strong association between alexithymia and somatization has been postulated in numerous studies, no systematic study has investigated the psychometric properties of the 20-item Toronto Alexithymia Scale (TAS-20) in a sample of patients with somatoform disorder yet. The purpose of this study was to ensure a ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.12.013
更新日期:2015-02-28 00:00:00
abstract::Parkinson's disease (PD) has broadly been associated with mild cognitive impairment (PDMCI) and dementia (PDD). Researchers have studied surrogate, neuroanatomic biomarkers provided by magnetic resonance imaging (MRI) that may help in the early diagnosis of this condition. In this article, four classification models (...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2012.06.001
更新日期:2013-08-30 00:00:00
abstract::To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seekin...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-1781(93)90108-s
更新日期:1993-07-01 00:00:00
abstract::The goal of the study was to describe with prospective methodology the therapeutic response to nortriptyline in the respiratory panic disorder (PD) subtype versus the non-respiratory subtype. A total of 118 PD outpatients (DSM-IV) were previously divided into respiratory (n=77) and non-respiratory (n=41) subtypes and ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00132-x
更新日期:2003-10-15 00:00:00