Renin mRNA is synthesized locally in rat ocular tissues.

abstract：PURPOSE:To investigate the association of nailfold capillaroscopy, heart rate variability (HRV), and clinical characteristics of glaucoma with the plasma matrix metalloproteinase-9 (MMP-9) level in normal-tension glaucoma (NTG). MATERIALS AND METHODS:We conducted a prospective, cross-sectional study on 25 patients wit...

journal_title：Current eye research

authors： Lee NY,Park HY,Park SH,Park CK

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Whether there is an interaction between eyes of individual subjects in refractive development is an important issue to guide experimental designs and help understand mechanisms involved in development of refractive errors. This study investigated whether spontaneous high myopia in one eye will affect refractive...

journal_title：Current eye research

authors： Ren Y,Xie R,Zhou X,Pan M,Lu F

更新日期：2011-06-01 00:00:00

abstract：:We have either introduced into the vitreous space or perfused through the anterior chamber of macaque monkey eyes two anionic tracers, anionic ferritin (AF) and horseradish peroxidase (HRP) and a cationic probe, cationic ferritin (CF). We have observed that the anionic molecules, but not the cationic one, are transpor...

journal_title：Current eye research

authors： Raviola G,Butler JM

更新日期：1985-04-01 00:00:00

abstract：PURPOSE:To learn if peripheral nerve pathways are necessary for corneal expansion and anterior segment growth under a 12-hr light:dark cycle or for the inhibition of corneal expansion under constant light rearing. METHODS:Recently hatched White Leghorn chicks under anesthesia received unilateral ciliary ganglionectomy...

journal_title：Current eye research

authors： Stone RA,Sugimoto R,Capehart C,Pendrak K,Lin T

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To investigate the agreement of angular locations of retinal nerve fiber layer (RNFL) defect margins in glaucomatous eyes by using red-free fundus photographs and Cirrus high-definition optical coherence tomography (OCT) RNFL deviation and thickness maps. METHODS:We examined 380 RNFL defects that showed clear ...

journal_title：Current eye research

authors： Hwang YH,Kim YY,Kim HK,Sohn YH

更新日期：2014-11-01 00:00:00

abstract：AIM:To compare patient satisfaction and experience after external dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode laser and to evaluate the change in quality of life following simultaneous bilateral DCR. METHODS:Prospective evaluation of 38 eyes of 19 patients with bilateral nasolacrim...

journal_title：Current eye research

authors： Yeniad B,Uludag G,Kozer-Bilgin L

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Unstable tear film characterized by shorting of tear break-up time (BUT) is associated with discomfort and dryness in contact lens wearers. The glycocalyx is thought to be crucial in maintaining the wettability and lubrication of the ocular surface. We evaluated the ocular surface glycocalyx in soft contact len...

journal_title：Current eye research

authors： Fukui M,Yamada M,Akune Y,Shigeyasu C,Tsubota K

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of this pilot study was to determine the presence of complement activation products in tears from pre- and postkeratoplasty eyes and the fellow eyes in order to investigate the activation of the classical and alternative pathways of the complement system in the early postkeratoplasty period. METHODS:Te...

journal_title：Current eye research

authors： Kerényi A,Nagy G,Veres A,Varga L,Füst A,Nagymihány A,Czumbel N,Süveges I,Füst G

更新日期：2002-02-01 00:00:00

abstract：:The effects of 4% epinephrine bitartrate and 0.5% timolol on ocular and optic nerve blood flow were studied in phakic and aphakic rabbit eyes using a radioactive microsphere (85Sr) technique. Either epinephrine or timolol was given topically as eight drops in the hour immediately preceding blood flow measurements (one...

journal_title：Current eye research

authors： Jay WM,Aziz MZ,Green K

更新日期：1984-10-01 00:00:00

abstract：:An image analyser installed in a 16 bit personal computer was used to measure grey levels in red free photographs of normal and glaucomatous eyes. Regional photographic image intensity and density were correlated with Humphrey Field Analyser results for corresponding areas of visual field. Two methods for standardisin...

journal_title：Current eye research

authors： Cooper RL,Eikelboom RH,Barry C

更新日期：1988-08-01 00:00:00

abstract：PURPOSE:Extracellular matrix (ECM) plays an important role in the regulation of cell function. The aging process may involve chemical modifications to ECM proteins, which may contribute to the aging of the Bruch membrane and pathogenesis of age-related macular degeneration (AMD). The purpose of this study is to investi...

journal_title：Current eye research

authors： Wang Z,Paik DC,Del Priore LV,Burch RL,Gaillard ER

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:The mechanisms involved in the reported beneficial effects of Calcium dobesilate monohydrate (CaD) for the treatment of diabetic retinopathy (DR) remain to be elucidated. The main aim of the present study is to examine whether CaD prevents early events in the pathogenesis of DR such as neurodegeneration and vas...

journal_title：Current eye research

authors： Solà-Adell C,Bogdanov P,Hernández C,Sampedro J,Valeri M,Garcia-Ramirez M,Pasquali C,Simó R

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To examine the effects of external modulation of epithelial-mesenchymal interaction on conjunctival epithelial cell differentiation characteristics. METHODS:Keratin K4 and laminin beta2 chain protein localization was examined in an organotypic model which facilitates the comparison of differentiation character...

journal_title：Current eye research

authors： Kurpakus MA,Lin L

更新日期：1999-01-01 00:00:00

abstract：:The lacrimal gland stores retinyl esters which are synthesized by the enzyme acyl CoA:retinyl acyl transferase. Retinol is released from retinyl ester reserves by retinyl ester hydrolase (REH). Since the lacrimal gland secretes retinol, this gland should also contain this enzyme. To identify bile salt-dependent REH ac...

journal_title：Current eye research

authors： Bernal DL,Ubels JL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:To evaluate the inhibitory effect of human fetal retinal pigment epithelium (HFRPE) on the activation of human T-cells. METHODS:Pure cultures of HFRPE cells were incubated with purified human T-cells in three different activation assays: 1) allogenic peripheral blood mononuclear cells; 2) OKT3 coated beads in ...

journal_title：Current eye research

authors： Rezai KA,Semnani RT,Farrokh-Siar L,Hamann KJ,Patel SC,Ernest JT,van Seventer GA

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the functional connectivity between the primary visual cortex and other cortical areas during rest in normal subjects and patients with comitant strabismus using functional magnetic resonance imaging (fMRI). METHODS:A prospective, observational study was conducted. Ten pati...

journal_title：Current eye research

authors： Yan X,Wang Y,Xu L,Liu Y,Song S,Ding K,Zhou Y,Jiang T,Lin X

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To detect the immunohistochemical changes in the main lacrimal glands of patients suffering from chronic ocular sequelae of Stevens-Johnson syndrome (SJS). METHODS:Histological sections of biopsies from the lacrimal gland of three chronic SJS patients (mean age, 33 years; 2 males) with severe dry eye disease (...

journal_title：Current eye research

authors： Singh S,Ali MJ,Mittal V,Brabletz S,Paulsen F

更新日期：2020-10-18 00:00:00

abstract：:The variation of central corneal thickness with age was measured weekly at 10am by ultrasound pachometry in 10 normal (5 to 19 weeks of age) and 10 alloxan-induced diabetic (9 to 19 weeks of age) rabbits. The diurnal variation of corneal thickness was also measured at 2 hour intervals for a period of 24 hours on both ...

journal_title：Current eye research

authors： Herse PR

更新日期：1990-05-01 00:00:00

abstract：:In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid mice (c57BL/6J-Pa/Pa), and those of littermate black mice (C57BL/6J-+/Pa) were examined ultrastructurally, histochemically, and biochemically. As controls, the eyes of black and congenic albino mice (C57BL/6J +/C2J and -C2J...

journal_title：Current eye research

authors： Ito M,Hashimoto K,Organisciak DT

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Recent studies have shown that the levels of interleukin (IL)-1beta, IL-6 and IL-8 are associated with the severity of infectious diseases. The purpose of this study was to investigate whether IL-1beta regulates the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colo...

journal_title：Current eye research

authors： Xue ML,Zhu H,Willcox M,Wakefield D,Lloyd A,Thakur A

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:Acanthamoeba keratitis is a sight-threatening corneal infection. It is known that: (i) more amoebae bind to the surface of injured corneas than to the normal corneal surface and (ii) mannose-containing glycoproteins (GPs) possess binding sites for Acanthamoeba. The present study was undertaken to determine whet...

journal_title：Current eye research

authors： Jaison PL,Cao Z,Panjwani N

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To investigate the relationship between retinal fractal dimensions (Dfs) and retinal circulation, which is impaired in early-stage diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM). METHODS:Using a laser Doppler velocimetry system, we measured the retinal vessel diameter (D) and blood ve...

journal_title：Current eye research

authors： Nagaoka T,Yoshida A

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:The mechanism by which prostaglandin(PG)F2 alpha increases uveoscleral outflow and lowers intraocular pressure in primates is not known. In cultured human ciliary muscle cells, PGF2 alpha induces the expression of the protooncogene c-fos which is known to induce the transcription of genes such as matrix metallo...

journal_title：Current eye research

authors： Lindsey JD,Kashiwagi K,Boyle D,Kashiwagi F,Firestein GS,Weinreb RN

更新日期：1996-08-01 00:00:00

abstract：PURPOSE:To explore the in vitro proliferative potential of human limbal epithelial cells after 31 degrees C organ-culture storage and to investigate putative factors influencing it. METHODS:185 cultures of limbal explants were carried-out either from full-thickness explants (n = 102) or from enzymatically dissociated ...

journal_title：Current eye research

authors： Zito-Abbad E,Borderie VM,Baudrimont M,Bourcier T,Laroche L,Chapel C,Uzel JL

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To investigate the biomechanical effect induced by radial keratotomy on outflow facility in paired, enucleated whole porcine eyes. METHODS:Freshly enucleated porcine eyes were perfused at a constant pressure of 10 mm Hg. Radial keratotomy (RK), with a 3.5 mm central clear zone and eight radial incisions, was p...

journal_title：Current eye research

authors： Becker HH,Eisenberg DL,Wang N,Steinert RF,Schuman JS

更新日期：1997-12-01 00:00:00

abstract：:DNA sequence analysis of overlapping shotgun and restriction fragments have revealed the entire sequence of the human lens fiber cell intrinsic membrane protein MP19 gene (also termed MP17, MP18, and MP20). The 8,056 bp MP19 gene contains 5 exons encoding a mature protein of 173 amino acids, which displayed a very hig...

journal_title：Current eye research

authors： Church RL,Wang JH

更新日期：1993-12-01 00:00:00

abstract：:Retinal degeneration is a leading cause of untreatable blindness in the industrialised world. It is typically irreversible and there are few curative treatments available. The use of stem cells to generate new retinal neurons for transplantation purposes has received significant interest in recent years and is beginni...

journal_title：Current eye research

authors： Langhe R,Pearson RA

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:1) To elucidate the role of collector channels in the aqueous humor outflow pathway 2) To suggest anatomic and functional methods of imaging collector channels in-vitro and in-vivo and 3) To discuss the role of such imaging modalities in the surgical management of glaucoma. METHODS:A thorough literature sea...

journal_title：Current eye research

authors： M Elhusseiny A,Jamerson EC,Menshawey R,Tam EK,El Sayed YM

更新日期：2020-10-01 00:00:00

abstract：:The new HERPCHEK (Dupont, No. Billerica, MA) enzyme immunosorbent assay (EIA) was used in a double-blind clinical study for rapid and specific detection of ocular herpes simplex virus (HSV) infection. This 4-hour assay can be used to demonstrate conclusively the presence of HSV antigen without culture and thereby rapi...

journal_title：Current eye research

authors： Dunkel EC,Pavan-Langston D,Fitzpatrick K,Cukor G

更新日期：1988-07-01 00:00:00

abstract：PURPOSE:Matrix metalloproteinases (MMPs) play an important role in the degradation of extracellular matrix (ECM) proteins in the retina. Breakdown of ECM proteins results in neovascularization and tractional retinal detachment, which eventually lead to the symptoms of proliferative diabetic retinopathy. Müller cells ar...

journal_title：Current eye research

authors： Miyata Y,Kase M,Sugita Y,Shimada A,Nagase T,Katsura Y,Kosano H

更新日期：2012-09-01 00:00:00