Binding of Acanthamoeba to [corrected] mannose-glycoproteins of corneal epithelium: effect of injury.

abstract：:A prototype automated flicker perimeter was used to investigate flicker luminance thresholds in glaucoma patients (n = 11), ocular hypertensives (high risk n = 10, low and intermediate risk n = 21) and normal controls (n = 10). Differential light sensitivity was measured for one eye of each subject using a flickering ...

journal_title：Current eye research

authors： Austin MW,O'Brien CJ,Wishart PK

更新日期：1994-10-01 00:00:00

abstract：:A reduced nicotinamide adenine dinucleotide phosphate (NAD(P)H)-dependent hydrogen peroxide-generating activity of rat ocular tissue was investigated cytochemically utilizing the cerium method. NADPH or NADH oxidation resulted in electron-dense fine granular deposits on the corneal epithelial and endothelial plasma me...

journal_title：Current eye research

authors： Atalla LR,Sevanian A,Rao NA

更新日期：1988-09-01 00:00:00

abstract：PURPOSE:This study was undertaken in order to investigate whether the production of vasodilatory prostaglandins is increased in the retinal vasculature of the diabetic rat. METHODS:Diabetes was induced in male Sprague-Dawley rats using streptozotocin. Diabetic rats were left uncontrolled for 3-4 weeks or were treated ...

journal_title：Current eye research

authors： Johnson EI,Dunlop ME,Larkins RG

更新日期：1999-02-01 00:00:00

abstract：:The ocular penetration pathways of three alpha 2-adrenergic agents (p-aminoclonidine, AGN 190342, and clonidine) were investigated in rabbits both in vitro and in vivo. The corneal permeabilities of the compounds correlated positively with their octanol/water distribution coefficients. The ocular drug absorption via c...

journal_title：Current eye research

authors： Chien DS,Homsy JJ,Gluchowski C,Tang-Liu DD

更新日期：1990-11-01 00:00:00

abstract：PURPOSE:To study whether there exists a relationship between retinal nerve fiber layer thickness and oxygen saturation and to identify whether perivascular thickness (pRNFL) or quadrant thickness (qRNFL) has a stronger correlation. METHODS:Patients without any detectable ocular abnormality on complete ophthalmic evalu...

journal_title：Current eye research

authors： Mohan A,Dabir S,Kurian M,Shetty R,Chidambara L,Kumar RS

更新日期：2016-09-01 00:00:00

abstract：:The content of rhodopsin in the eyes of 15 donors (30 eyes) was determined. Both retinal and pigment epithelial fractions were collected from each globe, extracted using 1% CTAB, and the rhodopsin difference spectrum of each fraction was obtained separately. The total amount of rhodopsin, obtained by summing the amoun...

journal_title：Current eye research

authors： Fulton AB,Dodge J,Schremser JL,Armstrong A,Lanier F,Dawson WW,Williams TP

更新日期：1990-12-01 00:00:00

abstract：:Two different measures of response to therapy were evaluated in a model of keratitis caused by Aspergillus fumigatus in Dutch-belted rabbits. Combined pre and post-inoculation treatment with oral fluconazole 37.5 mg/kg bid or itraconazole 40 mg/kg bid was compared to post-inoculation treatment only and untreated contr...

journal_title：Current eye research

authors： O'Day DM,Head WS,Robinson RD,Williams TE,Gedde S

更新日期：1992-01-01 00:00:00

abstract：:The cytoskeletal proteins of the human lens were studied by SDS-PAGE, 2-D electrophoresis and immunologically. Spectrin, vimentin and actin were identified in the superficial fiber cells of human lenses even to age 87 years. These proteins are lost from the deeper cortical and nuclear fiber cells, where a broad zone o...

journal_title：Current eye research

authors： Maisel H,Ellis M

更新日期：1984-02-01 00:00:00

abstract：PURPOSE:To evaluate how patient satisfaction after cataract surgery is associated with postoperative visual acuity, visual functioning, dry eye signs and symptoms, health anxiety, and depressive symptoms. PATIENTS AND METHODS:Fifty-four patients (mean age: 68.02 years) were assessed 2 months after uneventful phacoemul...

journal_title：Current eye research

authors： Szakáts I,Sebestyén M,Tóth É,Purebl G

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To investigate the association between corneal temperature on ocular surface and stability of tear film, and define the normal reference range of corneal surface temperature in the population of Pudong New Area, Shanghai, China. METHODS:Temperature of cornea (TOC) and tear film break-up time (BUT) were measu...

journal_title：Current eye research

authors： Yang W,Zhang L

更新日期：2017-05-01 00:00:00

abstract：:An image analyser installed in a 16 bit personal computer was used to measure grey levels in red free photographs of normal and glaucomatous eyes. Regional photographic image intensity and density were correlated with Humphrey Field Analyser results for corresponding areas of visual field. Two methods for standardisin...

journal_title：Current eye research

authors： Cooper RL,Eikelboom RH,Barry C

更新日期：1988-08-01 00:00:00

abstract：PURPOSE/AIMS:To evaluate the prognostic factors for the best corrected visual acuity (BCVA) and central subfield macular thickness (CSMT) after vitrectomy with internal limiting membrane (ILM) peeling for diabetic macular edema. MATERIALS AND METHODS:A total of 44 eyes of 35 patients who had undergone vitrectomy with ...

journal_title：Current eye research

authors： Yamada Y,Suzuma K,Ryu M,Tsuiki E,Fujikawa A,Kitaoka T

更新日期：2013-12-01 00:00:00

abstract：:3-aminotriazole (3AT) is known to reduce catalase levels in ocular tissues when given intravenously or orally. Rabbits were given either 4 ml/kg of a 3M solution of 3AT intravenously or a 2% solution as drinking fluid. Intravenous 3AT administration was followed at 4 hrs by an intracameral injection of hydrogen peroxi...

journal_title：Current eye research

authors： Birnbaum D,Csukas S,Costarides A,Forbes E,Green K

更新日期：1987-12-01 00:00:00

abstract：PURPOSE:The effects of repeated topical administration of the selective beta 2-adrenergic agonist fenoterol on the intraocular pressure and on the adenylyl cyclase activity in ciliary processes in rabbit were examined in order to detect their possible causal relationship. METHODS:Intraocular pressure was measured by p...

journal_title：Current eye research

authors： Cepelík J,Hynie S

更新日期：1997-10-01 00:00:00

abstract：:In the present study, using retinal ischemia as a model, we examined if different periods of ischemia and recirculation influenced the generation of reactive oxygen species, i.e. in hydrogen peroxide generation and nitroblue tetrazolium (NBT) reduction. Ischemia was induced for 30 and 90 min by ligation of the optic n...

journal_title：Current eye research

authors： Zhang H,Agardh CD,Agardh E

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:Psychiatric conditions and not just the treatments themselves might be involved in the pathophysiology of dry eye disease (DED). The aim of our study was to evaluate the association between depression and DED using objective and subjective tests in patients with newly diagnosed depressive disorder who were not ...

journal_title：Current eye research

authors： Tiskaoglu NS,Yazıcı A,Karlıdere T,Sari E,Oguz EY,Musaoglu M,Aslan S,Samet Ermiş S

更新日期：2017-05-01 00:00:00

abstract：AIM:To compare collared silicone punctal plugs to intracanalicular SmartPlugs for the treatment of moderate to severe dry eye. MATERIALS AND METHODS:In this prospective, randomized, single blind, clinical study, 30 patients (60 eyes) who had been diagnosed with moderate to severe dry eye syndrome were enrolled. Study ...

journal_title：Current eye research

authors： Rabensteiner DF,Boldin I,Klein A,Horwath-Winter J

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To determine the effect of prolonged exposure to high glucose on cellular behavior of normal human corneal epithelial cells (HCEC). METHODS:HCEC were cultured in medium under normal or high glucose conditions for 14 days. Proliferation was evaluated by direct cell counting and [(3)H]thymidine incorporation. Ce...

journal_title：Current eye research

authors： Fujita H,Morita I,Takase H,Ohno-Matsui K,Mochizuki M

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:Oxidative stress is considered a major factor in the deterioration of retinal pigment epithelium (RPE) cells in dry age-related macular degeneration (AMD). The MAPK ERK1/2 can be activated by oxidative stress, may exert both pro- and anti-apoptotic functions, and has recently been proposed as a major factor in ...

journal_title：Current eye research

authors： Koinzer S,Reinecke K,Herdegen T,Roider J,Klettner A

更新日期：2015-01-01 00:00:00

abstract：:Adult albino mice received tritiated thymidine either injected subcutaneously (333 microCi) every 6 hours for up to 36 hours, or administered in their drinking water for up to 74 days (about 45 microCi/day). Tissue sections were examined with autoradiography to determine the distribution of the label. Animals receivin...

journal_title：Current eye research

authors： McDonald TF,Green K

更新日期：1988-03-01 00:00:00

abstract：PURPOSE:The high prevalence of positive family history of keratoconus (KC) in KC patients is well-known. However, the results regarding the association between family history of KC and disease severity are controversial. The aim of this study was to evaluate the possible association between family history and severity ...

journal_title：Current eye research

authors： Naderan M,Rajabi MT,Zarrinbakhsh P,Naderan M,Bakhshi A

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:Post-surgical macular edema is an important clinical problem resulting from breakdown of the blood-retinal barrier (BRB) after surgery. This study was designed to develop a mouse model of post-surgical BRB breakdown. METHODS:Two 25-gauge needles, one for infusion and one for aspiration, were inserted through t...

journal_title：Current eye research

authors： Liu H,Demetriades AM,Xiao WH,Campochiaro PA,Vinores SA

更新日期：2004-06-01 00:00:00

abstract：:Purpose: To evaluate the correlation between pain during cataract surgery and preoperative anxiety.Methods: This prospective observational masked study included 103 eyes of 103 consecutive patients who underwent routine clear corneal incision phacoemulsification surgery at the Department of Ophthalmology, Rambam Healt...

journal_title：Current eye research

authors： Socea SD,Abualhasan H,Magen O,Zayit-Soudry S,Blumenthal EZ,Duvdevan N,Mimouni M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:To assess the distribution of dark-light changes in iris features and associated factors amongst American Caucasians, American Chinese and mainland Chinese aged 40 years and over. METHODS:Four gender- and age-matched cohorts: Caucasians, American Chinese, Southern Chinese and Northern Chinese comprised the stu...

journal_title：Current eye research

authors： Wang D,He M,Wu L,Kao A,Pekmezci M,Singh K,Lin S

更新日期：2012-07-01 00:00:00

abstract：:In the bovine lens the gamma IV-crystallin fraction is a principal determinant of the phase separation and opacification temperature, Tc (Siezen et al, Proc. Natl. Acad. Sci. USA 82, 1985, 1701). We have now measured the effect on Tc of purified gamma IV-crystallin solutions produced by a variety of reagents which aff...

journal_title：Current eye research

authors： Siezen RJ,Benedek GB

更新日期：1985-10-01 00:00:00

abstract：:Recently, all the structural features of non-proliferative diabetic retinopathy have been demonstrated in mice fed 30% galactose for 21-26 months. To determine whether changes in retinal matrix protein mRNA levels occur early in the course of murine diabetes we used a competitive RT-PCR method to quantitate retinal mR...

journal_title：Current eye research

authors： Nishikawa T,Giardino I,Edelstein D,Brownlee M

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To evaluate "in vivo" the effect of topical travoprost on the central corneal thickness (CCT) of rabbit eyes, and the changes in the CCT after acute increases of intraocular pressure (IOP) in these eyes. MATERIALS AND METHODS:This is an interventional, prospective, case-control, masked study. Topical travopros...

journal_title：Current eye research

authors： Bolívar G,Teus M,Arranz-Marquez E

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To evaluate choroidal thickness (CT) and retinal morphological changes in eyes with neovascular age-related macular degeneration (nAMD) following ranibizumab or aflibercept intravitreal treatment. MATERIALS AND METHODS:This was a prospective, observational, comparative study where 76 eyes of 76 consecutive pat...

journal_title：Current eye research

authors： Gharbiya M,Giustolisi R,Marchiori J,Bruscolini A,Mallone F,Fameli V,Nebbioso M,Abdolrahimzadeh S

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC). MATERIAL AND METHODS:A total of ...

journal_title：Current eye research

authors： Arslan S,Aydemir O,Güler M,Dağlı AF

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To evaluate changes in biometric parameters in myopic eyes. MATERIALS AND METHODS:412 eyes of 412 young myopic patients underwent ophthalmic examinations including assessments of refractive error, axial length (AL), anterior chamber depth (ACD), and central corneal thickness (CCT). By using spectral domain opt...

journal_title：Current eye research

authors： Chung HJ,Park CK

更新日期：2016-12-01 00:00:00