Abstract:
PURPOSE:To investigate the biomechanical effect induced by radial keratotomy on outflow facility in paired, enucleated whole porcine eyes. METHODS:Freshly enucleated porcine eyes were perfused at a constant pressure of 10 mm Hg. Radial keratotomy (RK), with a 3.5 mm central clear zone and eight radial incisions, was performed using a diamond knife with the blade length set at 100% of the paracentral corneal thickness, as measured by pachymetry. The fellow eye of each pair received sham RK as a control. RESULTS:Seven pairs of eyes were perfused (RK group n = 7, control n = 7). There was no significant difference in the mean baseline of outflow facility between the paired experimental and control eyes preoperatively (p = 0.5). After RK, outflow facility increased by 46% (p < 0.001) in the treatment group, compared to a 7% (p < 0.04) increase in the control group, resulting in a 39% increase in outflow facility attributed to RK (p < 0.001). CONCLUSIONS:Radial keratotomy produced a statistically significant acute increase in outflow facility in freshly enucleated porcine eyes. We believe that this increase results from steepening of the peripheral corneal curvature and the concomitant stretching of the iridocorneal angle. Further studies are needed to evaluate this effect in human eyes and in vivo.
journal_name
Curr Eye Resjournal_title
Current eye researchauthors
Becker HH,Eisenberg DL,Wang N,Steinert RF,Schuman JSdoi
10.1076/ceyr.16.12.1193.5027subject
Has Abstractpub_date
1997-12-01 00:00:00pages
1193-7issue
12eissn
0271-3683issn
1460-2202journal_volume
16pub_type
杂志文章abstract:PURPOSE:Modern refractive surgery and follow up relies on a knowledge of corneal thickness (CT) and shape, and the reliability of modern instrumentation providing such data is important. This study sought to determine the performance of the TOPCON SP-2000P specular microscope in measuring CT. The aims of this study wer...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.21.4.799.5542
更新日期:2000-10-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713683.2016.1221977
更新日期:2017-04-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
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journal_title:Current eye research
pub_type: 杂志文章,评审
doi:10.3109/02713688908995761
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abstract:PURPOSE:To determine the cellular mechanisms involved in the hypoxia-induced alteration of the retinal pigment epithelium (RPE) potentials and the light-evoked responses of the RPE in chicks. In addition, to determine the mechanisms involved in the recovery of the RPE during the post-hypoxic period. METHODS:In vitro p...
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pub_type: 杂志文章
doi:10.1076/ceyr.16.1.26.5116
更新日期:1997-01-01 00:00:00
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journal_title:Current eye research
pub_type: 临床试验,杂志文章
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journal_title:Current eye research
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
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journal_title:Current eye research
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更新日期:2019-10-01 00:00:00
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journal_title:Current eye research
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更新日期:1987-09-01 00:00:00
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更新日期:1999-05-01 00:00:00
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更新日期:2013-12-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
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更新日期:1999-09-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
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更新日期:1998-06-01 00:00:00
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更新日期:1997-02-01 00:00:00
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更新日期:2020-07-30 00:00:00